Yale Postdoctoral Positions

Yale University’s Nondiscrimination/Title IX Statements

Thank you for investigating postdoctoral opportunities at Yale.  Many faculty do not advertise open positions in their research groups, and you are encouraged to contact them directly to inquire about the possibility of training with them.  Other faculty advertise open positions in scholarly journals in their fields.  Finally, some post job openings on our website, and these positions are listed below.  Please click the links below to read more about each position and to find contact information for applying for the job.

Once you find a postdoctoral position your Yale department will contact you to begin the formal hiring process and to assist you in applying for an immigration visa to enter the United States if you require one.  Information about the visa process may be found at the Yale Office of International Students and Scholars website.

Postdoctoral position in the Department of Pathology (Braddock Lab)
Posting Date: September 24, 2020

A Postdoctoral Research Associate is sought in the Braddock laboratory to assist with our development efforts on investigating the pathogenesis and treatment of Rare Diseases. The Braddock lab demonstrable success designing and validating biologic therapeutics for human disease, and the position will span biochemistry, cell biology, protein design, and murine models of human disease. A major focus of the position will be in vitro and in vivo experiments to define the mechanism of a newly described form of osteoporosis described by our laboratory (J Bone Miner Res. 2020 Mar;35(3):528-539). The candidate may also participate in a newly developing project on autoimmune disease and tumor metastasis, and be involved in characterizing an newly developed animal model of metabolic disease associated with polymorphisms in ENPP1.

As discussed above, the candidate must be comfortable performing animal studies. Candidates with experience in primary eukaryotic cell culture, lentiviral transfection assays, murine models of tumor metastasis, and experience with RNAseq and bioinformatics are especially encouraged to apply, but all recent graduates from strong PhD programs in the biological sciences interested in translational research are also encouraged.

Applicants are requested to submit an application packet consisting of a cover letter, updated CV, the names of 3 references, and a copy of their academic transcripts.

Demetrios Braddock M.D. Ph.D.

Associate Professor of Pathology

Yale University School of Medicine

310 Cedar Street

New Haven CT 06510

Demetrios.braddock@yale.edu

Postdoctoral position in the Strazzabosco Lab, Department of Internal Medicine, Section of Digestive Diseases and Yale Liver Center
Posting Date: September 21, 2020

A post-doctoral position is available in Dr. Strazzabosco Lab, Department of Internal Medicine, Section of Digestive Diseases and Yale Liver Center at the Yale University School of Medicine. The primary aim of the project is to study the determinants of peribiliary fibrosis in fibropolycystic liver diseases. The applicant will work with a genetic mouse model harboring a deleting mutation in Pkhd1 and different cell systems including generation and culture of liver organoids and performing studies of scRNAseq.

Dr. Strazzabosco lab is part of the Yale Liver Center and the candidate will take advantage of the Cellular and Molecular Physiology and the Morphology Cores that includes a state-of-the-art imaging facility available for the lab members. The candidate will be supported by the laboratory’s experience in the field of liver cell biology, including handling and characterization of several transgenic mouse models of liver diseases and in vitro establishment of primary cell lines both mouse and human (iPSC) and liver organoids. The candidate will learn how to apply these methodologies to the study of genetic cholangiopathies, such as fibropolycistic liver disease. The candidate will have the opportunity to perform sophisticated molecular analysis such as scRNAseq. Finally, the candidate will participate to the seminars and meetings in the Section of Digestive Diseases, in the Liver Center and in the Department of Internal Medicine at Yale School of Medicine.

The candidate must have a Ph.D and proof of knowledge in molecular and cellular biology preferably but not limited to liver pathophisiology is required. 

Candidates should send a CV, a statement of research interests and the names of two references to: 

mario.strazzabosco@yale.edu

romina.fiorotto@yale.edu

Postdoctoral position in the Section of Pulmonary, Critical Care and Sleep Medicine (PCCSM),
Posting Date: September 9, 2020

Yale School of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine (PCCSM), is looking to hire a highly motivated Postdoctoral Associate to drive innovative translational research forward in the Yale ILD Center of Excellence.

The post-doctoral associate will work under the supervision of Dr. Erica Herzog and Dr. Danielle Antin-Ozerkis on human oriented research projects aimed at developing molecular biomarkers and treatments for patients with pulmonary fibrosis and related disorders.  The post-doctoral associate should be able to work independently as well as in a team of translational lung biologists in the lab which include pulmonologists, postdocs, clinical fellows and students. The major experimental tools that will be used include FACS, single cell RNA sequencing, ELISA, PCR on samples from patients with several forms of pulmonary fibrosis and interstitial lung disease.  

Job Qualification:

1. A recent graduate or about to graduate with an MD, or a PhD in the field of biology and immunology or similarly related fields.

2. Experience with translational work and biomarker studies is preferred but not necessary. Knowledge of major cellular and biochemical techniques such as FACS, single cell sequencing, ELISA and PCR is a plus.  

3. Candidate should be willing to write independent funding applications after first few years of their post-doctoral position with the goal for a career as independent investigator.

The individual will be expected to make a significant contribution to the educational and research missions of the section. There will be opportunities to work on projects autonomously while working collaboratively with faculty, staff, post docs, and students. Supervision of other research personnel and other related duties will be expected.  It is an excellent opportunity to learn about biomarker work in the context of clinical medicine and interventional trials.

Review of applications will begin immediately and will continue until the position is filled.  To apply, please submit a cover letter in the body of an email and CV/references as attachments to erica.herzog@yale.edu

Postdoctoral position in the Department of Pharmacology
Posting Date: September 2, 2020
The Department of Pharmacology at the Yale School of Medicine has immediate openings for highly motivated Postdoctoral Associates to investigate molecular mechanism underlying major and rare human diseases. Applicants with experience in use of murine model systems i.e. developing and characterizing the phenotype of genetically modified mice are encouraged to apply for the position.
 
Applicants should have a degree in Biochemistry, Cell Biology, Biophysics or a related field and should have extensive experience in recombinant protein production (E.coli and mammalian cells), experience with mammalian cell culture, as well as excellent written and
oral communication skills.
 
Interested candidates should send a current CV, a statement of research interests, and the names and contact information of three references to Nathan Kucera (nathan.kucera@yale.edu).
Postdoctoral position defining and modeling severe, pediatric immune diseases in the Department of Immunobiology
Posting Date: September 2, 2020

The laboratory of Dr. Carrie Lucas in the Immunobiology Dept at Yale University is looking to recruit a motivated postdoc scientist to join our team.   

The Lucas lab advances immunology through discovery and mechanistic investigation of severe, pediatric immunodeficiency or autoinflammatory disorders, often caused by single-gene defects. Starting with humans and extending to innovative mouse models, our work dives deeply into translationally relevant fundamental biology of T cells, B cells, and monocytes/macrophages. We use genetic, cellular, molecular, and in-vivo approaches to elucidate immune derangements and novel genes/pathways critical for healthy immune function. Current areas of emphasis include single-cell RNA sequencing and disease mechanisms in COVID-19-related ‘multisystem inflammatory syndrome in children’ (MIS-C), regulation of adaptive immunity, and inflammation at barrier tissues.  https://www.carrielucaslab.org

Interested candidates should send their CV to Dr. Lucas at Carrie.Lucas@yale.edu.  

Postdoctoral position in Early Psychosis Research
Posting Date: August 31, 2020

The Program for Specialized Treatment Early In Psychosis (STEP, www.step.yale.edu) at Yale University School of Medicine is recruiting for an immediately available 1-2 year position.

STEP includes an early detection and intervention service integrated with several clinical and services level research projects. STEP also hosts a Learning Health System with a custom-built informatics platform to support quality improvement and practice-based research.

The PDA will:

- Lead pilot analyses for grant submissions and publications;

- Develop new clinical research projects related to the mission of the Program;

- Oversee and participate in screening, diagnostic evaluation and structured assessment of early psychosis patients and families;

- Oversee and participate in maintaining our research databases;

- Support our clinical informatics platform and support quality improvement projects;

- Assist in referrals to several collaborating laboratories

This an excellent opportunity for those interested in a clinical research career related to serious mental illness. 

A doctoral degree is required (MD or PhD); licensure is preferred but not necessary.  Ideal candidates will have a strong research interest in psychosis and a strong record of publication in the area. At least one year of clinical experience with psychotic disorders in a clinical or research setting is required. Working familiarity with a statistical package is desirable, but statistical consultation is available.

Interested candidates should submit a CV, writing sample and two letters of recommendation to: 

Vinod H. Srihari, MD (vinod.srihari@yale.edu)
Professor and Director, STEP Program

Department of Psychiatry

Yale University School of Medicine

Connecticut Mental Health Center (CMHC)
34 Park Street
New Haven, CT 06519
 

Postdoctoral position in regenerative and immunomodulating effects of stem cells (Dr. Dereck Steinbacher Lab)
Posting Date: August 27, 2020

Postdoctoral research fellowships for highly qualified applicants are now available in the lab of Dr. Derek Steinbacher at the Yale School of Medicine. The laboratory focuses on a broad range of questions relevant to our understanding of bone, chondrogenic, and adipose tissue engineering. We are seeking postdoctoral scholars interested in research on the regenerative and immunomodulating effects of stem cells derived from various tissue sources (e.g. adipose, bone, muscle).

Among the current research projects include: 1) how chondrocyte respond to crush injury when combined with adipose-derived stem cells in vitro 2) how adipose-derived stem cells modulate vascularization and bone regeneration in 3D-printed bone scaffolds; and 3) how arteriovenous microvascular flow channels can enhance bone regeneration. The postdoctoral scholar will reside in a supportive environment with experienced mentors that will provide a research experience combined with training in grant writing and other critical academic skills. Applicants with a recent Ph.D. or M.D./Ph.D., publications in major journals and a strong background in tissue engineering, stem cell biology, immunology, cell biology, animal models and/or imaging are encouraged to apply.

Interested applicants should have a recent PhD degree in Biology, Biotechnology, Bioengineering Genetics, Biochemistry or equivalent research related field in addition to a strong background in molecular biology assays. Ideally, these will include experience with mammalian cell culture techniques, PCR, qPCR, immunostaining, ELISA, Western blot and FACS analysis. Experience in stem cell or bone biology is a plus. Prospective candidates will be part of a research team and expected to be highly motivated, passionate about science and collaborative.

Qualifications Required/Academic Background
Applicants with a recent Ph.D. or M.D./Ph.D., publications in major journals and a strong background in tissue engineering, stem cell biology, immunology, cell biology, animal models and/or imaging are encouraged to apply.

Salary/Stipend
commensurate with previous accomplishments and experience.

Application Procedure
Please submit interests, Curriculum Vita and names of three references to:  Derek.Steinbacher@yale.edu

Derek Steinbacher MD DMD, Professor, Yale School of Medicine
Director, Cleft and Craniofacial Surgery

Chief, Oral and Maxillofacial Surgery
Department of Surgery

Post-doctoral fellowship position in epigenetic dysregulation mechanisms in gastrointestinal cancers
Posting Date: August 24, 2020

A Postdoctoral Fellowship position is available in the laboratory of Dr. Nita Ahuja at the Department of Surgery, Yale School of Medicine. The research in the Ahuja laboratory is focused on understanding the epigenetic dysregulation in various cancers during disease progression using patient samples, patient derived organoids, PDX mouse and various cell line models, as well as translating the findings to develop novel detection biomarkers and identify novel treatment targets.

We are looking for motivated individuals interested in studying the molecular, cellular, and epigenetic dysregulation of gastrointestinal cancers and other disorders. Applicants should have a PhD or MD/PhD in biological sciences, molecular/cell biology, genetics or related fields. The candidate should be self-motivated and have a proven track record of productivity. Experience in RNA biology, epigenetic techniques, CRISPR and other gene editing techniques, immune-priming using epigenetic drugs, and analyzing genomic data sets will be an advantage. Candidates with a PhD in epigenetics would be given preference; however, candidates with 1 to 2 years of post-doctoral experience with a strong focus in epigenetics would also be considered. Any relevant experience in chromatin modulation biology will be plus. The candidate should possess excellent written and verbal communication skills, as well as ability to work collaboratively.

We are also looking for a lab manager with masters and minimum 2-3 years of experience with basic molecular and cell biology expertise and animal experience will be a plus.

Qualified applicants should email the application package (statement of interest, CV, and contact information for three referees) as a single pdf document. To apply or any other questions regarding the position please directly contact Anup Sharma (anup.sharma@yale.edu) for consideration.

Postdoctoral position in epigenetic dysregulation mechanisms in gastrointestinal cancers
Posting Date: August 18, 2020

A Postdoctoral Fellowship position is available in the laboratory of Dr. Nita Ahuja at the Department of Surgery, Yale School of Medicine. The research in the Ahuja laboratory is focused on understanding the epigenetic dysregulation in various cancers during disease progression using patient samples, patient derived organoids, PDX mouse and various cell line models, as well as translating the findings to develop novel detection biomarkers and identify novel treatment targets.

We are looking for motivated individuals interested in studying the molecular, cellular, and epigenetic dysregulation of gastrointestinal cancers and other disorders. Applicants should have a PhD or MD/PhD in biological sciences, molecular/cell biology, genetics or related fields. The candidate should be self-motivated and have a proven track record of productivity. Experience in RNA biology, epigenetic techniques, CRISPR and other gene editing techniques, immune-priming using epigenetic drugs, and analyzing genomic data sets will be an advantage. Candidates with a PhD in epigenetics would be given preference; however, candidates with 1 to 2 years of post-doctoral experience with a strong focus in epigenetics would also be considered. Any relevant experience in chromatin modulation biology will be plus. The candidate should possess excellent written and verbal communication skills, as well as ability to work collaboratively.

Qualified applicants should email the application package (statement of interest, CV, and contact information for three referees) as a single pdf document. To apply or any other questions regarding the position please directly contact Anup Sharma (anup.sharma@yale.edu) for consideration.

Postdoctoral positions in the Yale Cancer Prevention and Control Training Program
Posting Date: August 12, 2020

The Yale School of Public Health and the Yale Comprehensive Cancer Center (YCC) have received a Cancer Prevention and Control (CPC) T32 training award from the National Institutes of Health (NIH, T32 CA250803, 08/01/2020 – 07/31/2025), under which up to three (3) postdoctoral trainees are being recruited. Below are key aspects of the training program:

  • The Yale CPC Training Program aims to train postdoctoral fellows in five thematic areas critical to CPC: cancer etiology, cancer outcomes, lifestyle behavioral interventions, implementation science and community-engaged research.
  • The program is enabled by 22 Primary Faculty and 14 Resource Faculty at the Yale School of Public Health and School of Medicine, who have an outstanding track record in CPC research and mentoring of junior investigators.
  • Fellows will also directly participate and interact with the 7 YCC Research Programs and 14 YCC Disease-Aligned Research Teams.
  • Our training program will include a comprehensive mentoring program; a structured CPC Fellows research in progress meetings; participation in CPC research assistantship; and annual ½ day workshops in our 5 thematic areas.
  • Our program will select highly qualified and diverse candidates who wish to pursue a career in CPC. It is our goal that CPC Fellows will develop the knowledge and skills necessary to function independently, and develop and carry out innovative, impactful studies filling key gaps in CPC research, potentially changing the standard of care and impacting policy.
  • Selected candidates will receive stipend support at the prescribed NIH postdoctoral level based on NIH Notice NOT-OD-  20-070, and may request training related expenses up to $11,000 each year.

Application Details:

Review of applications will commence on August 21, 2020 at 5:00 PM and will continue until positions are filled.

Earliest start date: October 1, 2020.

Applications must be submitted online: http://apply.interfolio.com/77888

Requirements:

  • Applicants should have a doctoral degree in epidemiology, biostatistics, environmental health sciences, social and behavioral sciences, health policy, medicine, or other areas in life or data sciences, as well as a strong interest in CPC. Previous research experience in CPC is desirable but not required.
  • Applicants will need to meet NIH eligibility requirements for appointment to NRSA training grants. In particular, applicants must be US citizens or permanent residents at the time of application.
  • Applicants may not have received more than two years of previous support through a NIH postdoctoral training grant. Their support by the CPC T32 training program will not exceed two years.
  • Applicants must submit
    • A curriculum vitae that includes the names and contact information of two references; and
    • A one-page statement about your aims for postdoctoral training through the Yale CPC T32 training program.

Questions:

For questions about the application process, please contact Melinda Irwin (melinda.irwin@yale.edu) or Xiaomei Ma (xiaomei.ma@yale.edu) and be sure to include “CPC T32” in the Subject line of your email. 

Postdoctoral position in the laboratory of Dr. Vincent Pieribone at the John B. Pierce Laborator
Posting Date: August 6, 2020

A full-time position is available for a Postdoctoral Research Associate in the laboratory of Dr. Vincent Pieribone at the John B. Pierce Laboratory (http://jbpierce.org/research-laboratory/cellular-neurophysiology/), a nonprofit research institute affiliated with Yale University.

The Pieribone lab is developing state-of-the-art genetically encoded fluorescent voltage indicators and bioluminescent indicators for recording neuronal activity. The projects also include the study of bioluminescence pathways in native organisms in efforts to identify and characterize novel luciferases and their substrates that can be adopted for functional imaging.

The work involves design and development of high throughput screening platforms, and further optimization of the indicators for in vitro and in vivo imaging in various model organisms using multi- and single-photon microscopy.

REQUIREMENTS:
Candidates should hold a PhD in the field of Neuroscience, Molecular Biology, or Biochemistry and have an interest in systems neuroscience and the development and application of optical methods to study neuronal activity. Techniques of interest include electrophysiology, behavior, optical imaging using 2P and 1P microscopy, molecular cloning, protein expression and purification, protein engineering, and biochemistry. Applicants are expected to be able to design and execute independent research projects.

A coterminous postdoctoral appointment in the Department of Cellular and Molecular Physiology in the Yale School of Medicine is anticipated. The John B. Pierce Laboratory offers excellent benefits with employer paid health insurance and free parking.

TO APPLY:

Please submit a single PDF file to pdneuro@jbpierce.org including:
1) A cover letter with a (brief) statement of research experience and interest, 2) Curriculum Vitae, and 3) A list of three references.

Job Code: VP010

The John B. Pierce Laboratory is an Equal Employment Opportunity employer that does not unlawfully discriminate in any of its programs or activities on the basis of race, color, religion, sex, national origin, age, disability, veteran status, sexual orientation, gender identity or expression, or on any other basis prohibited by applicable law.

Postdoctoral postion in Optical imaging and optogenetics of the mouse olfactory bulb during virtual odor navigation
Posting Date: August 6, 2020

A postdoctoral position is available in the laboratory of Dr. Justus Verhagen at the John B. Pierce Laboratory, a nonprofit research institute affiliated with Yale University. The position is supported by a large collaborative NSF research project to elucidate the neurobiological basis odor source localization in transgenic mice. The project uses optical imaging and optogenetics of the olfactory bulb in a virtual odor navigation task to further our understanding of how animals navigate to odor sources.

REQUIREMENTS:

Candidates should be a new or recent PhD working in neuroscience or a related discipline, proficient in spoken and written English, efficient and self-motivated, and work well in a team environment. Prior experience with rodent behavior, imaging and surgery, Matlab, and the chemical senses is preferred.

A coterminous postdoctoral appointment in the Department of Neuroscience in the Yale School of Medicine is anticipated. The John B. Pierce Laboratory offers competitive salary and excellent benefits with employer paid health insurance and free parking.

TO APPLY:

Please send application with C.V., contact information for three references, and statement of interests to neuropd@jbpierce.org. Anticipated start date of October 2020. Job Code: JV003

Visit us at:  Verhagen Lab and Publications
 

The John B. Pierce Laboratory is an Equal Employment Opportunity employer that does not unlawfully discriminate in any of its programs or activities on the basis of race, color, religion, sex, national origin, age, disability, veteran status, sexual orientation, gender identity or expression, or on any other basis prohibited by applicable law.

Postdoctoral positions in microbial pathogenesis and translational medicine
Posting Date: July 17th, 2020

Two postdoctoral positions in the fields of microbial pathogenesis and translational medicine are available immediately. Ph.D. and M.D./Ph.D. degree with prior experience in the fields of cellular, molecular biology, genetics and biochemistry is required. Yale University offers a competitive postdoctoral salary, a comprehensive benefits package, and an excellent work environment.

To apply please send a curriculum vitae, description of research experience, and three references to: Dr. Choukri Ben Mamoun, Professor of Medicine and Microbial Pathogenesis, Department of Internal Medicine, Section of Infectious Disease, Yale School of Medicine. TAC-S215, 300 Cedar Street, New Haven, CT 06520. Email: choukri.benmamoun@yale.edu.

Postdoctoral position in the Grace Chen Lab in Immunobiology
Posting Date: July 9, 2020

We are seeking postdoctoral fellows to join the laboratory of Dr. Grace Chen in the Department of Immunobiology at Yale University. The Chen lab investigates the mechanisms and regulation of circular RNAs (circRNAs), a newly identified class of ubiquitous RNAs in essentially all eukaryotes and some viruses. Thus far, circRNAs have been found to function as miRNA sponges, regulate transcription, and act as templates for translation. However, there are still many unanswered questions: What other functions do circRNAs possess? How are circRNAs degraded? What are their interacting proteins? Specifically, we aim to understand how different layers of regulation including RNA modifications and cellular localization affect RNA function to enable new insights into both normal function and how dysregulation leads to disease. The Chen Laboratory applies molecular, cellular, and chemical biology techniques coupled with next-generation sequencing to address these questions. We aim to generate novel therapies based on our new insight about circRNA function and regulation. For more information, visit gracechenlab.org.

Applicants should have recently completed a Ph.D. degree in molecular biology, chemical biology, immunology or genomics. High priority will be given to those candidates with strong backgrounds in RNA or chemical biology. 

Interested applicants please send a brief statement of interest and curriculum vitae with contact information for three references to the PI Dr. Grace Chen at ye.grace.chen@yale.edu.

Postdoctoral position in Cancer Biology in the Department of Therapeutic Radiology (Hayman Lab)
Posting Date: July 8, 2020

The Hayman Lab, led by Thomas Hayman, MD, PhD, in the Department of Therapeutic Radiology at Yale University is recruiting a highly motivated and creative postdoctoral associate.  We are a cancer biology lab that is focused on utilizing genetic approaches to understand and exploit resistance mechanisms to DNA damage. 

Our research program has a particular interest in studying the interplay between the cell intrinsic immune machinery and DNA repair processes using in vitro cell models, genetic screens (such as CRISPR and RNA interference), and animal models.  We have a strong translational focus that is founded in a preclinical mechanistic understanding of basic biological processes with the ultimate goal of shaping these discoveries into therapeutic strategies for cancer patients.

We are seeking a candidate who will contribute to the discovery and translation of biological processes that modulate tumor responses to DNA damaging therapies (e.g. radiation) and immunotherapy.  Interested applicants should hold a PhD. or M.D. with considerable laboratory experience and a strong background in cancer biology, molecular biology, genetics, radiation biology or other related fields.  Prior experience with in vivo animal tumor models, CRISPR/Cas9, IF/IHC and DNA damage assays is highly desired, but not a requirement.  The candidate should be self-motivated and have a proven track record of productivity.  Excellent written and oral communication skills are expected. 

How to Apply:

Candidates should send a Curriculum Vitae, a cover letter detailing research interests and career goals, and contact information for three references to Dr. Thomas Hayman (thomas.hayman@yale.edu).

Postdoctoral position in molecular and circuit mechanisms in the Department of Genetics ( Jiang Lab)
Posting Date: July 1, 2020

The Jiang laboratory is looking for highly motivated candidates with PhD or MD/PhD degree from molecular genetics, molecular biology, and neuroscience for a Postdoctoral Associate appointment.  The successful candidate will work on NIH supported projects to study the molecular and circuit mechanisms underlying autism using mouse models including Shank3, Shank2, and Angelman, and new autism models. Experience and skills in molecular biology, optogenetics and chemo-genetics, ex and in vivo recording, mouse behaviors, and mouse models are preferred.  Anticipated start date will be after September 1, 2020.

Please respond with CV, a short description of relevant expertise, and the names of three references by email to yong-hui.jiang@yale.edu.

Postdoctoral position in molecular genetics and neuro-epigenetic mechanisms in the Department of Genetics (Jiang Lab)
Posting Date: July 1, 2020

The Jiang laboratory is looking for highly motivated candidates with PhD or MD/PhD degree from molecular genetics, molecular biology, and neuroscience for a Postdoctoral Associate appointment.  The successful candidate will work on NIH supported projects to study molecular genetics and neuro-epigenetic mechanisms and develop new treatments for Prader-Will and Angelman syndrome. Dissect the role of epigenetics in brain function and neurodevelopmental disorders.  Experience and skills in molecular genetics and epigenetics, genomics, CRISPR/Cas9, IPSC and brain organoids and mouse models are preferred.  Anticipated start date will be after September 1, 2020.

Please respond with CV, a short description of relevant expertise, and the names/emails of three references by email to yong-hui.jiang@yale.edu.

'Postdoctoral position in Vascular Biology investigating the mechanisms that control arterial disorders
Posting Date: June 30, 2020

Postdoctoral positions are available in the Laboratory of Dr. Raul J Guzman, Chief, Division of Vascular and Endovascular Surgery at Yale University School of Medicine.

The research program focuses on investigating the mechanisms that control arterial disorders including calcification and restenosis. The laboratory uses multiple approaches including gene knockdown, overexpression, and deficiency in cell culture, ex vivo organ culture, small animal models, and transgenic mice. Its goal is to identify novel mechanisms that control pathologic arterial responses and to develop therapeutic agents to prevent them.

Qualified applicants are those who have earned a Ph.D. or equivalent degree with a strong background in vascular biology or related fields. The candidates should have prior experience with cell and molecular biology and small animal techniques. Ideal candidates will have the ability to independently design, execute and troubleshoot experiments. They will have the ability to collect, analyze and interpret data in preparation for manuscript publication. They will also possess the ability to communicate in English both verbally and in writing to present experimental findings at internal meetings and scientific conferences.

To apply for this position please submit your CV, a cover letter, and contact details of three references to yujun.cai@yale.edu

Postdoctoral Position in MDS and Leukemia in the Yale Comprehensive Cancer Center
Posting Date: June 29, 2020

A postdoctoral position is available in Dr. Stephanie Halene’s laboratory at Yale University School of Medicine, to study cancer mutations and aberration in splicing (Liang et al., Leukemia, 2018) and RNA modifications (Gao et al., Immunity  2020) in MDS and Leukemia. The Halene Lab is also studying the effect of COVID 19 on hematologic malignancies. Located in the Yale Comprehensive Cancer Center, the Halene laboratory studies RNA splicing, RNA modifications, and genomics in hematopoietic stem cell biology and in MDS and Leukemia.

We use state of the art tools and techniques, including RNA immunoprecipitation coupled with high-throughput sequencing (eCLIP), single cell sequencing, m6A CLIP,  Riboseq, RNAseq, targeted exome seq, as well as biochemistry and functional genomics in cell lines, primary mouse models, and primary patient samples and state of the art bioinformatic analyses. In collaboration with the laboratory of Dr. Richard Flavell we have developed a unique, highly efficient xenotransplantation model for the study of human hematopoiesis, MDS, and leukemia, presenting a powerful tool to study mechanism and therapeutic approaches in vivo (Song et al., Nat Comm, 2019).

Candidates with strong background in RNA biology, hematopoiesis/leukemia, genomics,  mouse models, and/or molecular biology are particularly encouraged to apply. Strong bioinformatic skills are a plus. Applicants with a Ph.D. should submit curriculum vitae and names of three references to Dr. Stephanie Halene (halene.lab.yale@gmail.com).  Please enter “Postdoc Position” in subject line of e-mail.

Postdoctoral position in the Department of Psychiatry Division of Substance Abuse
Posting Date: June 24, 2020

The Department of Psychiatry at Yale School of Medicine invites applications for two postdoctoral associate positions focused on research in the areas of tobacco use prevention, cessation, and regulation. We have three available positions with start dates ranging from now until the positions are filled.

The postdoctoral associates could participate in projects focused on the 1) development and evaluation of e-cigarette cessation interventions in adolescent populations in collaboration with the Tobacco Research in Youth (TRY) Group, and 2) the conduct of tobacco regulatory research in adolescent and adult populations within the Yale Tobacco Center of Regulatory Science (TCORS). Within the TCORS, postdoctoral associates will have access to training on tobacco regulatory science and the opportunity to participate in a programmatic line of research aimed at investigating how flavors, sweeteners, and other constituents, as well as social media content, impact use behaviors and the appeal and addictive potential, of e-cigarettes and other tobacco products.

Competitive candidates should have: 1) a PhD in clinical, developmental, counseling, or health psychology, or a doctoral degree in public health, family studies, social work, or social welfare; 2) a strong research background; 3) interest in pursuing an academic career; 4) interest and/or background in tobacco regulatory science or tobacco prevention and cessation among youth and young adults. Strong data analytical skills would be appreciated but not required.

All postdoctoral associates will participate in core seminars on research and data analytic methods, grant development, and professional development as well as in seminars and colloquia that cover related topics, such as the ethical conduct of research and current topics in substance abuse prevention and tobacco regulatory science. Post-doctoral associates will have an opportunity to conduct independent research under the mentorship of Drs. Suchitra Krishnan-Sarin and Grace Kong.

To apply: Applicants should email a CV, a statement of interests that outlines their qualifications, research interests, and future goals, and three letters of recommendation to Dr. Grace Kong: Grace.Kong@yale.edu.

Postdoctoral position in translational research in multiple sclerosis (Pitt Laboratory)
Posting Date: June 11, 2020

The Pitt laboratory is looking for a talented senior postdoctoral fellow with background in cell biology to join our team. We conduct translational research in multiple sclerosis (MS) with the goal of understanding the mechanisms that underlie MS progression and neurodegeneration.

Our laboratory in the Department of Neurology, Yale School of Medicine, is embedded in a highly collaborative, translational neuroimmunology program that includes T cell biology, genetics and computational biology. 

The candidate will participate in our larger effort to examine how genetic risk variants dysregulate glial cell function in multiple sclerosis and Alzheimer’s disease (Ponath et al. Nature Comm. 2018), and to identify cellular subpopulations and their interactome in chronic and remyelinating MS lesions (Park et al. Acta Neuropath Comm. 2019).

Our laboratory uses cutting-edge technologies such as generation of human iPSC-derived astrocytes and microglia, highly multiplexed histological imaging (staining of individual section with 40+ antibodies), advanced computational tools for spatial analysis, as well as purification of astrocyte and oligodendrocyte nuclei from MS, Alzheimer and Parkinson’s tissue for transcriptomic and genomic profiling with sNuc-Seq and ATAC-Seq.

The candidate should have a broad neurobiology background and experience with cell-based assays in primary cultures. Expertise in generating and differentiating of iPSCs into CNS cells is desirable. Please respond with CV, a short description of relevant expertise, representative publications and the names of three references by email to david.pitt@yale.edu. The successful candidate will join the Department of Neurology for a minimum of 2 years.

Postdoctoral position in the Department of Neurology (Pitt Laboratory)
Posting Date: June 11, 2020

The Pitt laboratory is looking for a motivated junior postdoctoral fellow with background in cell biology to join our team. We conduct translational research in multiple sclerosis (MS) with the goal of understanding the mechanisms that underlie MS progression and neurodegeneration.

Our laboratory in the Department of Neurology, Yale School of Medicine, is embedded in a highly collaborative, translational neuroimmunology program that includes T cell biology, genetics and computational biology. 

The candidate will drive the development of astrocyte-derived exosomes as biomarkers for MS progression and other neurodegenerative conditions. Our laboratory uses cutting-edge technologies such as generation of human iPSC-derived astrocytes and microglia, highly multiplexed histological imaging (staining of individual section with 40+ antibodies), advanced computational tools for spatial analysis, as well as purification of astrocyte and oligodendrocyte nuclei from MS, Alzheimer and Parkinson’s tissue for transcriptomic and genomic profiling with sNuc-Seq and ATAC-Seq.

The candidate should have a broad neurobiology background and experience with cell-based assays in primary cultures. Please respond with CV, a short description of relevant expertise, representative publications and the names of three references by email to david.pitt@yale.edu. The successful candidate will join the Department of Neurology for a minimum of 2 years.

Postdoctoral position to study brain and leptomeningeal metastasis in the Department of Pathology (Nguyen Lab)
Posting Date: June 1, 2020

A fully funded post-doctoral position is available to study the molecular mechanisms of metastasis in the central nervous system. Applicants will have the opportunity to develop various aspects of their career, working in the departments of Pathology, Medicine, and Cancer Center. The applicant will also be part of a multi-disciplinary team working in collaboration with the Yale SPORE in lung cancer, Yale Brain Metastasis program, and pharmaceutical companies. More information can be found at http://medicine.yale.edu/lab/nguyen/

Applicants should recently hold or be nearly completing an MD or PhD degree in the biological sciences or related field. Candidates with experience in one or more of the following areas are encouraged to apply:

-Epigenomics.
-Immunofluorescent microscopy.
-Animal models of disease.
-Neuroinflammation.

Interested applicants should direct their CV, a brief statement of research interests, and arrange for three letters of recommendation to be sent to don.nguyen@yale.edu.

Don X. Nguyen
Associate Professor

Yale University School of Medicine

Department of Pathology

Assistant Cancer Center Director for Research Development

Yale Cancer Center