Yale Postdoctoral Positions

Yale University’s Nondiscrimination/Title IX Statements

Thank you for investigating postdoctoral opportunities at Yale.  Many faculty do not advertise open positions in their research groups, and you are encouraged to contact them directly to inquire about the possibility of training with them.  Other faculty advertise open positions in scholarly journals in their fields.  Finally, some post job openings on our website, and these positions are listed below.  Please click the links below to read more about each position and to find contact information for applying for the job.

Once you find a postdoctoral position your Yale department will contact you to begin the formal hiring process and to assist you in applying for an immigration visa to enter the United States if you require one.  Information about the visa process may be found at the Yale Office of International Students and Scholars website.

In accordance with university requirements for a safe return to in-person university operations, all faculty, staff, and postdoctoral and postgraduate trainees will be required to be fully vaccinated against COVID-19 by August 1. For additional information, please visit Yale University’s Office of the President . Read Here

Postdoctoral positions in microbial pathogenesis and translational medicine(Mamoun Lab)
Posting Date: October 14, 2021

Postdoctoral positions in the fields of microbial pathogenesis and translational medicine are available immediately in the Mamoun Lab. Candidates with Ph.D. or M.D./Ph.D. degrees with prior experience in molecular biology, genetics and immunobiology are encouraged to applyd. Yale University offers a competitive postdoctoral salary, a comprehensive benefits package, and an excellent work environment.

To apply please send a curriculum vitae, description of research experience, and three references to: Dr. Choukri Ben Mamoun, Professor of Medicine and Microbial Pathogenesis, Department of Internal Medicine, Section of Infectious Disease, Yale School of Medicine. TAC-S215, 300 Cedar Street, New Haven, CT 06520. Email: choukri.benmamoun@yale.edu.

Postdoctoral position at the Center for Industrial Ecology at Yale University School of the Environment
Posting Date: October 14, 2021

The Center for Industrial Ecology at Yale University has a Postdoctoral Scholar position available for a project involving the life cycle assessment of additive manufacturing. 3D printing is an emerging manufacturing technology that has gained increasing attention and interest in the industry and the industry itself is looking to improve its environmental footprint overall. The goal of this project is to understand the potential environmental impacts and economic implications of additive manufacturing compared to conventional manufacturing pathways. The postdoc will work with Prof. Marian Chertow and Prof. Yuan Yao.

The position will focus on:

  1. Conducting environmental life cycle assessment (LCA) and life cycle cost analysis (LCC) for metal industrial parts manufactured by binder jetting 3D printing and conventional technologies (e.g., CNC).
  2. Evaluating the potential environmental benefits of lightweighting and part geometry optimization.
  3. Working with internal and external researchers in engineering, environmental science, and industrial ecology and leading the LCA for different additive manufacturing scenarios and technology pathways.

The ideal candidate should have a Ph.D. in Mechanical Engineering or other engineering disciplines with LCA and LCC experience in 3D printing and manufacturing technologies. Candidates with strong publications in relevant topics are highly encouraged.

Interested candidates should email a cover letter and their CV, along with relevant publications and a list of at least three references to Prof. Marian Chertow marian.chertow@yale.edu and Prof. Yuan Yao, y.yao@yale.edu. The position will be open until filled.

Kavli Postdoctoral Award for Academic Diversity
Posting Date: October 8, 2021

The Kavli Institute for Neuroscience at the Yale School of Medicine is committed to fostering and supporting an inclusive and representative neuroscience research community. Diversity is vital to achieving excellence and innovation in scientific research. The Kavli Postdoctoral Award for Academic Diversity seeks to support exceptional scholars who bring a diversity of perspectives, identities, and backgrounds to academic research, including those from groups that are historically underrepresented in the sciences. This Award will support up to two years of mentored research in the neurosciences at Yale University, including salary, benefits, and a research allowance. Awardees will join a nurturing community that promotes scientific excellence through mentorship, training, and professional development.

Important Dates

Please submit all application materials, including letters of reference, at this link: apply.interfolio.com/86909, by November 15th, 2021. The research is anticipated to begin any time in 2022.

Terms

The award will provide $60,000 for salary support, and standard postdoctoral employee benefits for up to two years. An additional $20,000 allowance can support relevant research and travel expenses, including up to $3,000 toward relocation.

Eligibility     

  • Candidates must have completed their doctoral degree prior to the award start date.
  • Candidates must have sponsorship from the Yale faculty mentor with whom they will conduct neuroscience research. Candidates who are not currently at Yale must contact and attain this sponsorship prior to applying.

Application Procedure

You will need written support from the Yale faculty member with whom you would like to complete your research for application submission. Please identify and contact them prior to applying.

Application Form

  • All documents must be uploaded to the application portal in PDF format at apply.interfolio.com/86909

Curriculum Vitae

Please provide a current CV, including publications that are online, in print, pending, or deposited in public repositories such as bioRxiv.

Personal Statement (max one page)

Please include a one-page max (arial 11, single-spaced) personal statement to address the following:

  • Research experience and major accomplishment(s).
  • Statement describing how your unique experiences will contribute to a diversity of perspectives, identities, and backgrounds.
  •  Your future goals.

Research Plan (max two pages)

A two-page research plan (arial 11, single-spaced), excluding references. An additional page with figures may be included.

Letters of Reference

  • The thesis advisor should provide a letter to address the quality and originality of the candidate’s research and their potential for a career in science.
  •   One person familiar with the candidate should provide a letter speaking to the candidate’s research experience, qualifications, and aspirations.

Letter of Faculty Sponsorship (max two pages)

  • The sponsoring Yale faculty mentor should provide a letter of support to address the candidate’s qualifications and proposed research projects. The letter should discuss the candidate’s potential contributions to the mentor’s research program, how the mentor will foster the development and advancement of the candidate, and the mentor’s ability to support the candidate’s effort and research beyond the two-year award.
Postdoctoral position in Cancer Metabolomics (Johnson Lab)
Posting Date: October 8, 2021

A postdoctoral position is available in the laboratory of Dr. Caroline H. Johnson at the Department of Environmental Health Sciences, Yale School of Public Health, Connecticut, USA. The applicant will use LC-MS-based metabolomics analysis to understand the role of dietary and microbial metabolites in colorectal cancer and related signaling pathways. The type of analysis will include preparation of biological samples, mass spectrometry analysis (QTOF), data processing and statistical analysis. The applicant can also be involved in the development of mechanistic studies under additional supervision.

Applicant skills

The individual must hold a Ph.D. degree in a Chemistry or Life Sciences discipline and have demonstrated experience in LC-MS-based metabolomics. Experience in R programming is desirable. The candidate will be expected to apply for additional external postdoctoral funding and assist in writing other grant applications.

Interested applicants should submit a CV, cover letter, and contact information for 3 references.

Please apply online: http://apply.interfolio.com/96418

For questions, please contact Dr. Johnson at caroline.johnson@yale.edu.

http://medicine.yale.edu/lab/cjohnson/

Postdoctoral position in RNA biology and immunology at Yale University (Grace Chen Lab)
Posting Date: October 7, 2021

We are seeking postdoctoral fellows to join the laboratory of Dr. Grace Chen at Yale University in the Department of Immunobiology. The Chen lab aims to generate novel therapies to treat cancer and autoimmune diseases based on our basic science understanding about RNA function and regulation. We investigate the mechanisms and regulation of circular RNAs (circRNAs), a newly identified class of ubiquitous RNAs in essentially all eukaryotes and some viruses. Thus far, circRNAs have been found to function as miRNA sponges, regulate transcription, and act as templates for translation. However, there are still many unanswered questions: What other functions do circRNAs possess? How are circRNAs degraded? What are their interacting proteins? Specifically, we aim to understand how different layers of regulation including RNA modifications, secondary structure, and cellular localization affect RNA function to enable new insights into both normal function and how dysregulation leads to disease. The Chen Laboratory applies molecular, cellular, and chemical biology techniques coupled with next-generation sequencing to address these questions. For more information, visit http://gracechenlab.org.

Applicants should have recently completed a Ph.D. degree in molecular biology, chemical biology, immunology or genomics. High priority will be given to those candidates with strong backgrounds in RNA or chemical biology. Interested applicants please send a brief statement of interest and curriculum vitae with contact information for three references to the PI Dr. Grace Chen at ye.grace.chen@yale.edu.

Postdoctoral position in Metabolism (Vatner Lab)
Posting Date: October 7, 2021

Daniel Vatner M.D., Ph.D. in the Yale School of Medicine Section of Endocrinology and Metabolism is looking to hire a highly motivated postdoctoral fellow to do exciting translational basic science studies, with an emphasis on in vivo physiology and molecular biology.  We investigate the physiology of the metabolic syndrome, studying numerous rodent models and human subjects with state of the art techniques.  We seek to understand the metabolic fluxes that drive excess triglyceride production in the setting of insulin resistance; additionally, in collaboration with other laboratories at the School of Medicine, we are investigating links between metabolic dysfunction and the progression of nonalcoholic fatty liver to NASH.  The postdoctoral fellow will work on projects both independently and in multi-laboratory collaborations (working alongside students, fellows, technicians, and other investigators).

Candidates for this position should be recent graduates with a PhD, MD, or equivalent degree.  Expectations include those important for growing the fellow’s research career, including presenting at meetings and preparing manuscripts, and those important for a properly-functioning laboratory, including participation in mouse colony maintenance and laboratory organization.

Interested applicants should send a cover letter briefly outlining research experiences, career goals, references, and expected availability date, along with a CV to daniel.vatner@yale.edu.

Postdoctoral position in metastasis and drug resistance
Posting Date: October 7, 2021

A fully funded post-doctoral position is available to study mechanisms linking organ specific metastasis to drug resistance in lung cancer. Successful applicants will lead a joint collaboration between the laboratories of Don Nguyen and Katerina Politi, and will further participate in a multi-disciplinary research within the NCI’s Patient-derived models of cancer consortium, the Yale SPORE in lung cancer and additional collaborators. More information can be found at http://medicine.yale.edu/lab/nguyen/ and https://medicine.yale.edu/lab/politi/.

Applicants should recently hold or be nearly completing a PhD or MD/PhD degree in the biological sciences, genomics, or related field. Candidates with experience in one or more of the following areas are encouraged to apply:
 

  • Epigenomics
  • Cancer biology
  • Animal models of disease
  • Tumor microenvironment

Interested applicants should direct their CV, a brief statement of research interests, and arrange for three letters of recommendation to be sent to Wendy Folsom  (wendy.folsom@yale.edu.)

Yale University is an Afirmative Action/Equal Opportunity employer. Our laboratories value diversity among our students, staff, and faculty and we strongly welcome applications from women, persons with disabilities, and underrepresented minorities.

Katerina Politi, PhD
Associate Professor
Department of Pathology and Internal Medicine (Section of Medical Oncology)

Co-leader Cancer Signaling Networks Program
Yale Cancer Center
Yale University School of Medicine
333 Cedar Street, SHM-I 234D
New Haven, CT 06510 USA
 

Don X. Nguyen, Ph.D

Associate Professor

Yale University School of Medicine

Department of Pathology

Assistant Cancer Center Director for Research Development

Yale Cancer Center

Brady Memorial Laboratory

P.O. Box 208023

New Haven, Connecticut, 06520-8023

Postdoctoral position available at Yale School of Medicine – mTOR signaling and mRNA translation (Thoreen Lab)
Posting Date: October 7, 2021

A postdoctoral position is available in the laboratory of Carson Thoreen in the Department of Cellular and Molecular Physiology at Yale School of Medicine. We are a multi-disciplinary lab that studies the mTOR signaling pathway, a master regulator of growth and metabolism. Our lab previously discovered how mTOR post-transcriptionally controls the ATF4 transcription factor, a master regulator of amino acid metabolism (Park et al. Cell Reports, 2017), and terminal oligopyrimidine (TOP) mRNAs, a conserved mRNA family that encode hundreds of essential proteins (Thoreen et al, Nature, 2012; Philippe et al., PNAS, 2020).

A position is currently available for creative and motivated RNA-loving candidates. Strong organizational and communication skills are a must. Proficiency in transcriptome-scale methodology, RNA biochemistry, and basic bioinformatics are desired. Available projects are focused on new mechanisms linking mRNA translation and stability, nutrient regulation of mRNA translation in the liver, and localized translation of mRNAs in neurons.

Applicants should email a current CV and cover letter describing research interests to carson.thoreen@yale.edu. Lab website: http://campuspress.yale.edu/thoreenlab.

Postdoctoral position at Yale School of Medicine, Department of Psychiatry, Program for Recovery and Community Health
Posting Date: October 5, 2021

The Yale School of Medicine, Department of Psychiatry, Program for Recovery and Community Health is recruiting one postdoctoral fellow for a 2-year appointment to begin July 1st, 2022. The fellowship provides focused research training in the area of competitive and integrated employment for people with psychiatric disabilities. 

To ensure that we provide the highest quality research training, we have designed our program to be comprised of the following combination of didactic, experiential, practical, and individualized components. Each postdoc will:  

1) Receive training in recovery-oriented practice and participatory, community-engaged research, highlighting, in particular, the role of competitive employment as a central pathway to recovery; 2) acquire hands-on research experience by being offered choices of engaging as a collaborator in on-going research projects; 3) develop, conduct, and complete their own independent research project under the close supervision and mentorship of senior faculty; and 4) have access to the full range of elective lectures, seminars, discussion groups, and social support offered by the Postdoctoral Affairs Office of the Yale School of Medicine and the Yale Center for Clinical Investigation.  

To be eligible to apply, prospective postdoctoral candidates must hold a doctoral degree or its equivalent at the time of appointment. All trainees will be required to pursue research training full-time. Applications of persons with a disability and/or part of an underrepresented minority population are encouraged. To apply, please send a single PDF documenting the following to mark.costa@yale.edu: 1) Cover letter detailing previous research experience, interests, and career goals; 2) CV; 3) Names and contact information of three academic references. 

Postdoctoral position in the Department of Genetics (Reilly Lab)
Posting Date: September 28, 2021

The Reilly Lab in the Genetics Department Yale School of Medicine is seeking postdoctoral researchers for funded projects to understand how genetic variants impact human health, evolution, and disease. We seek to answer a fundamental question remaining in biology: “how do genetic changes lead to functional changes at the molecular, cellular, and phenotypic level?”

We’re especially interested in understanding the role of non-coding, cis-regulatory elements (CREs) in the genome, with a focus on variation within them. Genome-wide association studies have identified hundreds of thousands of genetic variants associated with human health and disease, but mechanistic traction has been limited. Similarly, natural selection is a powerful driver of human genetic variation between populations and may still impact modern traits or disease (e.g. height, sickle cell anemia).

The Reilly lab develops and applies new high-throughput experimental approaches to interrogate the genome, such as non-coding CRISPR screens and the Massively Parallel Reporter Assay, as part of our work in an ENCODE functional characterization center. Computationally, we also develop machine-learning approaches to predict the functions of these CRE perturbations. Together with these new tools, we use evolution as a powerful lens for characterizing genomic signals of positive selection that impact modern human phenotypes and diseases.

The lab has three main foci:

1. Developing new, large-scale experimental screens to perturb CREs, and new computational tools to model their function
2. Identifying evolutionary adaptive alleles likely impacting modern human phenotypes
3. Applying these functional genomic tools to phenotypically interesting loci important for human disease and evolution.

We’re looking for inquisitive, creative, and passionate researchers to join our team. We’re a multi-disciplinary group with a variety of backgrounds including genomics, math, biochemistry, machine-learning, and population genetics. Similar backgrounds are a good fit, but many PhD or MDs interested in human evolution, building new genomic tools, or analyzing complex data would find a project in our lab. The lab prides itself on building an inclusive, supportive, and collaborative environment, deeply committed to the tailored professional development of all of the lab’s trainees.

Interested applications should email Steve<mailto:steven.k.reilly@yale.edu>, briefly describing your scientific interests, how they intersect with our lab’s interests, and include your CV. Post-doctoral applicants should also submit a Diversity, Equity, and Inclusion statement and include copies of their major manuscripts.

Postdoctoral position in the Clinical Cytogenetics Lab in the Department of Genetics
Posting Date: September 28, 2021

The Clinical Cytogenetics Lab in the Department of Genetics at Yale School of Medicine is seeking a postdoctoral candidate interested in validating and utilizing genomic technologies for clinical diagnosis.
 

Our lab provides conventional cytogenetic analyses and chromosome microarray assay for detecting chromosomal abnormalities and pathogenic copy number variants in both clinical and research settings ( https://medicine.yale.edu/lab/cytogenetics/ ).
We are looking for a highly motivated Postdoctoral Associate to (1) develop and validate novel genomic testing for detecting recurrent structural rearrangements in various types of cancers; (2) perform independent research on specific case cohort, and (3) participate in collaborative research.
 

Candidates with experience in molecular and cytogenetics techniques, microarray analysis, next-generation sequencing (especially long read genome sequencing), and bioinformatics are encouraged to apply. Ideal candidates would have a background in genetics or molecular biology. Excellent communication and writing skills are required. Salary is on the standard of school and department guidelines.
 

Interested applicants should send a CV, a cover letter and three references to peining.li@yale.edu

Postdoctoral Fellowship on Qualitative Methods for Implementation Science in the Prevention, Screening and Treatment of Heart, Lung, and Blood Health Disorders
Posting Date: September 24, 2021

Application Deadline: Applications are reviewed on a rolling basis and reviews will begin on October 1, 2021.

http://apply.interfolio.com/95240

Fellowship Overview

The Center for Methods in Implementation and Prevention Science (CMIPS) in the Yale School of Public Health and the Yale School of Medicine are seeking a Postdoctoral Research Fellow on Qualitative Methods for Implementation Science in Heart, Lung, and Blood Health Promotion to contribute to research advancing the use and development of qualitative methods in implementation science research. Expertise in implementation science theories, models and frameworks, and/or interest in gaining expertise in these and their application to implementation science are important aspects of this Fellowship. Current projects that may be of interest to applicants include (but are not limited to) qualitative and implementation science research on integration of hypertension screening and treatment into HIV clinics in Sub-Saharan Africa; reduction of cardiometabolic risk through improvements in the workplace food and physical activity environment in India, Nepal and South Africa; developing rapid approaches for qualitative research in global multilingual settings, a systematic review identifying trends and gaps in qualitative methods use in implementation research, and developing qualitative approaches to complement digital health technology implementation. The Fellow will have the opportunity to pursue a Masters in Health Science focused on implementation science through the Yale Medical School, supported by this training grant.

We invite scholars from diverse backgrounds to apply for this Fellowship. The Fellow should be prepared to address critical gaps in knowledge by 1) conducting research to inform the development, implementation, and evaluation of qualitative methods in intervention-based or implementation research focused on the prevention, screening and treatment of heart, lung and blood disorders, 2) innovating new and improved qualitative methodological approaches, and 3) provide technical assistance and training to other scholars, students, and communities in the use of qualitative  and implementation science approaches to research. The primary goal of the Fellowship is to support the further career development of a scholar with the potential to become an innovative research leader working to enhance qualitative and implementation science methods. We seek scholars who can publish at the highest level, reach the widest audience, and impact both their substantive topical field, and the methodological field. The postdoctoral fellow will receive mentorship and support from CMIPS, Yale School of Public Health and Yale Medical School leadership and staff and closely collaborate on projects.

Requirements

Required qualifications include a Ph.D. in public health, anthropology, sociology, or a related field. Candidates should demonstrate qualitative research skills, experience in qualitative data analysis, excellence in scientific written and oral communication skills, experience or training in qualitative methods, and a strong commitment and passion to advance methods innovation, appreciation for the importance of racial/ethnic diversity in science, and the desire and ability to work both independently and collaboratively as part of a team. Applicants must be US citizens or non-citizen nationals, or individuals lawfully admitted for permanent residence at the time of appointment. Additional details on citizenship requirements are available in the HHS Grants Policy Statement.

The position will be at least 1 year, renewed annually, for at least two years, as interest and funding permit. The position will begin as early as February 2022, but is flexible depending on the candidate’s timeline. 

To apply, please provide a cover letter outlining qualifications specific to this description, a paragraph outlining two potential ideas for qualitative methods innovation in health intervention research, your academic CV, and the names and emails of 3 individuals who could serve as references via the application portal. This is a 100% FTE position using the standard NIH postdoctoral position salary range.

Any questions related to the position can be directed to Professor Ashley Hagaman, Department of Social and Behavioral Sciences and Center for Methods in Implementation and Prevention Science, Yale School of Public Health, at ashley.hagaman@yale.edu..

Apply here: http://apply.interfolio.com/95240

Postdoctoral position in Cancer Biology (Muzumdar Lab)
Posting Date: September 23, 2021

The Muzumdar Lab (Department of Genetics and Yale Cancer Biology Institute) is seeking a postdoctoral associate interested in cancer biology to join our growing research team.
 

Our lab is an inclusive team that seeks to understand how genetic alterations cooperate with environmental and host factors to drive the progression of the most recalcitrant cancers in hopes of devising novel strategies for cancer prevention, interception, and therapy. As part of the Yale Cancer Biology Institute and Yale Cancer Center, the lab offers an outstanding and fully-resourced training environment to prepare for a career in academia or industry.
 

We leverage genetically-engineered cell line and mouse models to study genetic and adaptive (epigenetics, metabolic, signaling) mechanisms that mediate: 1) response and resistance to oncogene (KRAS) inhibition in pancreatic cancer; 2) progression from early to advanced disease in lung and pancreatic cancers; and 3) and obesity as a cancer driver. We further strive to train the next generation of cancer research scientists in a diverse work environment that fosters belonging and growth. Read more about our team and current projects on our lab website (https://medicine.yale.edu/lab/muzumdar/) or on Twitter (@MuzumdarLab).
 

Candidates with recent MD, PhD, or MD/PhD degrees and experience in cancer biology, molecular biology, genetics, or signal transduction are encouraged to apply. Successful candidates will be expected to develop their own projects aligned with the lab’s core focus and work collaboratively with other postdocs, graduate students, and other trainees in the lab towards reaching their research goals. Experience with genetically-engineered mouse cancer models is preferred but not required.
Interested applicants should send 1) a cover letter describing their background, research interests, and career goals; 2) CV with bibliography; and 3) names/contact information for three references to mandar.muzumdar@yale.edu<mailto:mandar.muzumdar@yale.edu>.

Postdoctoral position Environmental Health Sciences Department at the Yale School of Public Health (Deziel Lab)
Posting Date: September 23, 2021
Dr. Nicole Deziel, Associate Professor in the Environmental Health Sciences Department at the Yale  School of Public Health, has an immediate opening for a postdoctoral associate in environmental  exposure science and environmental epidemiology. Professor Deziel’s research is focused on applying spatial metrics, biomonitoring techniques, and environmental measurements to provide comprehensive 
and quantitative assessments of exposure to traditional and emerging environmental contaminants in population-based studies of cancer and adverse birth outcomes.Particular exposures of interest include environmental carcinogens, thyroid hormone disrupting  chemicals, and unconventional oil and gas development (“fracking”). Consideration of disproportionate burdens of exposures (“environmental justice”) and the combination of environmental and social stressors are important aspects of the work.
 
Position Details
Position will involve leading innovative research that includes quantitative data analysis,  graphical exploration and display of data, and writing manuscripts. The position is available for  one year at a competitive salary with benefits, with a possibility of extension. The postdoctoral  associate will receive dedicated mentoring and training and have opportunities to present at  professional conferences and apply for grant funding.
 
Qualifications
Qualifications include a PhD in environmental health, epidemiology, biostatistics, or related  discipline, strong quantitative and coding skills, excellent oral and written communication skills,  and a strong interest in exposure science.
 
Please send a cover letter explaining your qualifications and interests, along with a current CV 
and contact information for three references to Nicole.deziel@yale.edu.
For further information about our school, please visit http://publichealth.yale.edu
 
 
Postdoctoral position in the Department of Pathology (Gopal Lab)
Posting Date: September 20, 2021

Motivated PhD graduates seeking postdoctoral fellowship training in the cell biology of neurodegenerative disease are invited to apply to the Gopal Laboratory in the Department of Pathology at Yale University.  Successful candidates will utilize live cell and super-resolution imaging techniques, biochemistry, and mass spectroscopy/CyTOF, in primary neurons and mouse models, iPSC-derived neurons, and/or patient tissue samples to define the molecular mechanisms driving assembly, transport, and cellular functions of neuronal ribonucleoprotein (RNP) complexes under physiologic conditions and in neurodegenerative disease. Emphasis will be placed on defining molecular mechanisms relevant to the pathophysiology of age-related inherited and sporadic neurodegenerative diseases, including Amyotrophic lateral sclerosis (ALS), Frontotemporal dementia, and Alzheimer’s disease, with a long-term goal of guiding the development of novel therapies. Recent work has used live cell and super-resolution imaging techniques to study the biophysical properties of neuronal ribonucleoprotein granules and has shown that ALS-linked mutations fundamentally perturb the dynamic properties and transport of neuronal RNP complexes.

Successful candidates will be guided to develop independent research careers under the mentorship of Dr. Gopal.  Strong written and verbal communication skills, as well as a track record of publications in peer-reviewed journals, are required.  Candidates should have prior expertise in cellular and molecular neurobiology, genetics, and the design and characterization of CRISPR and/or transgenic mouse models. Prior experience with iPSC-derived neurons, CRISPR gene-editing techniques, RNA imaging, quantitative analysis of imaging data, and/or characterizing mouse models of neurodegenerative or neurodevelopmental disorders is highly desirable.

Interested candidates should forward a cover letter, curriculum vitae, and a 1-2 page description of their research interests, together with the names and contact information of three references via email to:  pallavi.gopal@yale.edu

Pallavi Gopal, M.D., Ph.D.

Assistant Professor of Pathology

Department of Pathology

Yale School of Medicine

310 Cedar Street, Lauder Hall LH108

New Haven, CT 06519

Review of applications will begin on September 30, 2021.

Postdoctoral position in the Department of Ophthalmology and Visual Science (Bakhoum Lab)
Posting Date: September 15, 2021

Post-doctoral positions available for highly motivated and creative candidates to join the Mathieu Bakhoum Laboratory at Yale University School of Medicine.

Candidates with a background in cell biology, genetics, epigenetics or mouse work are highly encouraged to apply.

The Bakhoum laboratory (www.bakhoumlab.org) focuses on understanding mechanisms that drive metastasis in melanoma. Our goal is to translate this knowledge to develop non-invasive biomarkers for diagnosis and metastatic surveillance, and to identify targets that can be employed to treat the primary and metastatic disease.

Approaches utilized will include next-Generation sequencing, single-cell genomics, high-resolution imaging, mouse models, molecular cloning and biochemical assays.

Postdoctoral researchers will have direct access to state-of-the-art microscopy as well as world-class animal and core facilities. Furthermore, they will be part of a vibrant and collaborative scientific environment at Yale University.

Post-doctoral fellow candidates must hold a PhD., MD., or other equivalent doctoral degree and have strong laboratory and analytical skills.

All applications should be sent to mbakhoumlab@gmail.com and include the following items merged as a single-PDF file:

1) Cover letter (2-page maximum) indicating current and future research interests and expected availability dates;
2) Curriculum Vitae;
3) Reprints of up to two publications (optional);
4) Names of three references

Postdoctoral position with the Adolescent Initiatives Team at the Yale Center for Emotional Intelligence
Posting Date: September 15, 2021

The Yale Center for Emotional Intelligence, part of the Child Study Center at the Yale University School of Medicine, conducts research and teaches people of all ages how to develop their emotional intelligence. Our work focuses on (1) the development and impact of social and emotional skills among diverse populations, including education settings and organizations, and (2) the mechanisms by which social and emotional skills and training impact significant life outcomes.

We are looking for a Postdoctoral Associate to join the Adolescent Initiatives Team (PI: Dr. Jessica Hoffmann) on a series of three, 3-year Deep Dive projects meant to work closely with partner schools to support and follow their SEL progress and practices over time. Each branch of this project has its own unique elements: (1) Detail the

implementation of RULER in two middle schools through quantitative and qualitative data collection; (2) Employ YCEI’s suite of assessment tools to support a Connecticut private school in achieving their communitywellness

priorities; (3) Collaborate with a local district on understanding the benefits of parallel implementation of RULER for High School and inspirED (the YCEI’s flagship approach to SEL and complementary student empowerment program).

The postdoctoral associate’s primary responsibility will be to execute data collection and analysis across the three projects. They will also be expected to support in other tasks related to the team’s research, such as the preparation of research articles, grant writing, and the design of future studies. Dr. Jessica Hoffmann will oversee day-to-day work assignments and be the primary supervisor. The Director of Research, Dr. Christina Cipriano, will provide additional supervision and professional support.

Skills and Qualifications

  • Doctorate (PhD or EdD) in psychology, education, or a related field

  • Specialization or demonstrated interest in the study of adolescent development, emotions, and psychological assessment

  • Excellent statistics skills, including experience with multi-level modeling and working with qualitative data

  • Demonstrated ability to work with school communities (educators, students, families), conduct focus groups, and maintain school relations

  • Excellent communication skills (e.g., writing research papers, giving presentations)

  • Strong project management skills

  • Ability to work both independently and collaboratively

The anticipated start date is November 1, 2021.

In accordance with university requirements for a safe return to in-person university operations, all faculty, staff, and postdoctoral and postgraduate trainees will be required to be fully vaccinated against COVID-19. For additional information, please visit https://your.yale.edu/work-yale/workplace-guidance/workplace-guidance-faqs.

To Apply

Please send a cover letter and CV to jessica.hoffmann@yale.edu. Review of applications will begin immediately and continue until the position is filled. Please have contact information available for three references upon request.

ABOUT THE YALE CENTER FOR EMOTIONAL INTELLIGENCE

Emotions drive learning, decision making, creativity, relationships, and health. The Yale Center for Emotional Intelligence uses the power of emotions to create a more effective and compassionate society. Helping children and adults develop emotional intelligence is central to the mission of the Center. To date, schools have been at the center of these efforts. RULER, the Center’s signature program, draws on leading pedagogical practices as well as advances in psychology and neuroscience, and it has been honed through years of classroom observation, interviews, and the most demanding evaluations. Creating awareness—both of self and others—about emotions and developing the skills of emotional intelligence can improve children’s prospects in life and contribute, in turn, to healthier, more compassionate families, workplaces, and communities. RULER does this by teaching adults and children the skills of emotional intelligence. Since 2005, more than 600 schools have implemented RULER, affecting the lives of over 500,000 students. Accordingly, we integrate emotional intelligence skill building, the basis of RULER, into their everyday practices and into classroom curricula across grade levels.

Posdoctoral position at the Yale Cancer Center (Patel Lab)
Posting Date: September 15, 2021

A postdoctoral position is available in the laboratory of Dr. Abhijit Patel at the Yale Cancer Center and the Yale School of Medicine (www.patel-lab.org).  Our laboratory has a highly translational focus, with the overall goal of developing non-invasive diagnostic tools for early detection and surveillance of cancer.  We have developed innovative technologies to enable ultrasensitive measurement of cancer-associated genomic and epigenomic alterations in cell-free DNA in blood.  Most recently, we have developed methods for measuring genome-wide methylation signatures in blood to identify early-stage cancers or early recurrences after therapy.  In addition, this platform technology is generating rich whole-methylome datasets from which insights can be gained on tumor heterogeneity, clonal evolution, and therapeutic sensitivity/resistance.  Our lab is currently focused on establishing the clinical utility of these technologies and exploring potential new translational applications.

We seek a highly motivated individual with an interest in cancer genomics, epigenomics, and translational cancer research.  Candidates must have a strong research track record, and must hold a Ph.D. and/or M.D. degree.  A background in nucleic acid biochemistry, bioinformatics, and/or data science is advantageous, but we welcome talented applicants from all fields of biomedicine.  Researchers with a background in chemistry might find our lab to be a particularly good fit. 

If you would like to join our efforts to create new diagnostic tools with the ultimate goal of improving cancer outcomes, please send your CV and a brief cover letter to:  abhijit.patel@yale.edu

Selected candidates will be asked to provide contact information for telephone references. Interviews can be conducted in person or via Zoom, depending on geographic constraints.

Postdoctoral position in the Department of Pathology (Braddock Lab)
Posting Date: September 10, 2021

The Yale School of Medicine, Department of Pathology, is seeking a highly motivated postdoctoral associate to work in the Braddock lab, which investigates severe unmet medical illness through the study of Rare Diseases with a focus on dysregulated mineralization of the vasculature and the skeleton. The laboratory uses a combination of biochemistry, protein engineering, novel transgenic animal models, RNAseq, bio-informatics, and proteomics to identify novel regulators of mineralization. Our goal is directed toward discovery of mechanisms explaining these severe phenotypes and to design innovative therapeutic approaches relevant to disorders of mineralization. Recent work includes the identification of osteoporosis associated with heterozygous ENPP1 deficiency and the successful development of a therapeutic entering clinical trials for Generalized Arterial Calcification of Infancy (GACI), Autosomal Recessive Hypophosphatemic Rickets Type-2 (ARHR2) and Pseudoxanthoma Elasticum (PXE).

The recent success of the lab translating basic scientific findings into the clinical arena offers a unique and valuable training opportunity for motivated scientific researchers seeking training in translational medicine. The laboratory has a record of close collaborations with clinicians treating patients with ENPP1 deficiency to correlate preclinical findings with novel human phenotypes and therapeutic responses. The ideal candidate will have experience with one or more of the following techniques: osteoblastic differentiation assays, molecular biology, RNAseq, and proteomics based assays to identify protein-protein interaction.

Interested candidates should forward a CV and short description of research interests together with the names and addresses of three references to:

Demetrios.braddock@yale.edu

-or-

Demetrios Braddock, M.D./Ph.D.

Departments of Pathology

Yale University School of Medicine

310 Cedar Street, BML-165

New Haven, CT 06510

Postdoctoral positions in the Department of Pharmacology
Posting Date: September 9, 2021

Two postdoctoral associate positions are now available for enthusiastic individuals who are interested in studying protein tyrosine phosphatases and chemokine-GPCR’s. The projects involve 1) investigating the mechanisms of MAP kinase phosphatases as novel therapeutic targets for the treatment of human diseases such as metabolic disease, heart disease and cancer and 2) using mouse genetics to generate and characterize humanized chemokine and GPCR models of cancer. These projects will utilize chemical biology, structural biology, biochemical and mouse genetic techniques to define the molecular basis of MAP kinase phosphatase and chemokine-GPCR signaling. There are opportunities to study small molecules and other biological and cell-based therapeutics under development. The two individuals will be responsible for developing and maintaining an independent research project and will require expertise in either structural and chemical biology or biochemical and mouse genetic skills.The position will necessitate a high level of collaborative interactions with other research teams at Yale University in a multi-disciplinary environment. Support for academic enrichment and career development will be core to the postdoctoral research positions.

Successful candidates should have a Ph.D. with experience in mouse genetics, molecular biology, signaling, and biochemistry. Interested candidates that have a broad interest in intracellular signal transduction should send their CV and names of three references to:

Professors Anton M. Bennett, Ph.D. 

and Elias Lolis, Ph.D.

Yale University School of Medicine

Department of Pharmacology

333 Cedar Street

New Haven, CT 06520-8066

anton.bennett@yale.edu

elias.lolis@yale.edu

Open Postdoctoral position in pediatric immune diseases in the Department of Immunobiology (Lucas Lab)
Posting Date: September 1, 2021

We are looking to recruit motivated postdoc scientists to join our team.   

The Lucas lab strives to advance basic and translational immunology through discovery and mechanistic investigation of severe, pediatric immunodeficiency and autoinflammatory disorders, often caused by single-gene defects. Starting with patients and extending to mouse models, our work aims to dive deeply into translationally relevant biology of adaptive and innate immune cells by combining genetic, cellular, molecular, and in-vivo approaches. 

Interested candidates should send their CV to Carrie.Lucas@yale.edu.  

Postdoctoral Associate in Stem Cell and Organoid Modeling for Dyslexia
Posting Date: September 1, 2021

Postdoctoral Associate position in Stem Cell and Organoid Modeling for Dyslexia available in the Departments of Pediatrics, Genetics,the Yale Progam for Learning Disability Research, and the Yale Child Health Research Center at the Yale University School of Medicine. This is a position in a collaborative, multi-disciplinary laboratory studying the function of dyslexia genetic variants in neurons and brain organoids differentiated from human embryonic stem cells (hESCs). The Gruen lab uses genomic approaches including CRISPR/CAS to interrogate mechanisms of genes associated with learning disabilities, especially dyslexia, specific language impairment, and verbal trait disorders.

The current research focus is directed toward characterizing the role of dyslexia genes and variants: 1) in neuronal differentiation and migration; 2) knock-out/knock-down/knock-in models and their effects on transcription, neuronal stage-specific markers of differentiation, electrophysiologic properties, and conductivity; 3) cerebellar differentiation and cerebellar-cortical connections; and 4) in critical metabolic pathways that could be tested as potential small-molecule drug targets. These studies capitalize on the laboratory’s expertise in human genetics, stem cell biology, imaging-genetics, and computational methods.

Candidates should have a PhD with experience in stem cell biology, related areas of biology or genetics, and possess skills in stem cells and approaches to genomic editing. Candidates should understand the context and implications of the research so as to be able to interpret and apply the theoretical knowledge required to conduct these studies. The range of duties includes, but is not limited to: project planning, experimental design, developing methodology, conducting procedures, modifying procedures as needed, data collection and analysis, project management. The candidate will be expected to regularly develop and deliver presentations at lab meetings, and prepare publications and reports. Candidates will also have the opportunity to present to the larger Yale community and external scientific community through national and international meetings. Candidates with a strong interest in neurobehavioral genetics—including reading disability, attention deficit/hyperactivity disorder, and language impairment—are particularly encouraged to apply.

Requirements:
PhD in life sciences, biological sciences, stem cell biology, genetics, or related discipline
 
Key Responsibilities & Essential Functions:
• Expand subject matter expertise and research awareness through investigation of the primary literature towards effective study design and independent research project leadership
• Successful execution of complex experiments and procedures in the context of a larger study design; and ability to recognize and implement quality control measures where needed
• Data analysis and design of data documentation / reporting; leads efforts to modify and adapt research methodologies; ensures compliance with regulatory standards
 
Knowledge, Skills, and Abilities:
• Previous experience in an academic setting performing statistical analysis; interpreting and evaluating results, and compiling data preferred.
• Explicit interest in pursuing and completing eligibility requirements for continuing studies or career in biomedical and/or clinical research; or in pursuing a medical profession.
• The ability to work in a demanding, fast paced, team-oriented environment, while maintaining a high-level of professionalism
• Leads and initiates good safety practices and a demonstrated history of safe conduct
• Exceptional technical skills, facility with technical software and databases and ability develop technical documents and presentations
• Ability to interact in a productive, professional and positive manner to enhance the outcome of the goals of the research program
• Demonstrated team player with professional, positive attitude and willingness to be flexible
• Consistently maintains a positive work environment
• Demonstrated ability to positively influence the behavior of teammates
• Ability to work flexible shifts (evening/week-end/holiday)
• Regular, reliable and consistent attendance
 
Interested applicants should send curriculum vitae and contact information for three references to Dr. Jeffrey R. Gruen, Yale Child Health Research Center, 464 Congress Avenue, New Haven, CT 06520-8081, or E-mail: jeffrey.gruen@yale.edu
 
 
EMPLOYER:
Yale University School of Medicine
COMPANY URL:
LOCATION:
New Haven, CT, USA
Postdoctoral position in liver biology in the Section of Digestive Diseases and Liver Center (Iwakiri Lab)
Posting Date: August 30, 2021

The Iwakiri Lab in the Section of Digestive Diseases and Liver Center at Yale School of Medicine is seeking a postdoctoral candidate interested in studying liver vasculature and lymphatics in association with liver disease.

Our lab provides an excellent multidisciplinary environment with collaborators in the Vascular Biology and Therapeutics Program and Liver Center at Yale University.

Candidates with experience in flow cytometry analysis, confocal microscopy and bioinformatics are encouraged to apply.  Ideal candidates would have a background in immunology, neurobiology or molecular biology.  Excellent communication and writing skills are requirements for this position.  Salary is on the NIH standard.

Interested applicants should send a CV and a cover letter describing research interest, reasons to apply to my lab and 3 references to yasuko.iwakiri@yale.edu.

Postdoctoral position in gene therapy and immunotherapy
Posting Date: August 26, 2021

Postdoctoral positions are available in the Department of Internal Medicine Section of Infectious Diseases, (Priti Kumar, PI) at the Yale University, School.  Our lab conducts translational research with a focus on treatment of diseases caused by RNA viruses such as HIV-1, SARS-Cov2, and West Nile (https://medicine.yale.edu/profile/priti_kumar/).

We are looking for highly talented, creative, and independent-minded post-doc candidates to fit into any one of the major endeavors of the lab:

-Developing targeted in vivo delivery systems for CRISPR/Cas-based tools as gene therapy for HIV

-Investigating therapeutics for the cure of HIV in humanized mouse models of HIV infection

-Investigating interventions for the treatment of SARS-Cov2 in rodent models

The expertise/experiences required for this position include:

  • Expertise in basic virology/molecular/cell biology/immunology techniques such as virus culture, neutralization detection, lentiviral vector production molecular cloning, cell culture, Western blot, flow cytometry, ELISA, protein expression and purification, knowledge of CRISPR technology, microscopy, etc.);
  • Prior experience in working with animal model systems is highly desirable. Experience in generating humanized mouse models is a strong positive, but not a requirement. Relevant training is available upon hire.
  • Previous experience working in BSL-3 laboratories is a plus;
  • Basic statistical knowledge is highly desirable;
  • Excellent oral communication and written skills in English, with good organizational and analytical abilities.

Candidates should have a Ph.D.  in Biological Sciences such as immunology, virology, biochemistry, molecular and cell biology, and other related fields. The salary will be according to NIH guideline, and commensurate with experience.

Applicants should submit (in a single PDF file) a brief letter of interest summarizing qualifications, a curriculum vitae, and the names and addresses of three individuals willing to provide letters of reference to Priti Kumar, PhD via email: priti.kumar@yale.edu

Postdoctoral position in metastasis and drug resistance
Posting Date: August 24, 2021

A fully funded post-doctoral position is available to study mechanisms linking organ specific metastasis to drug resistance in lung cancer. Successful applicants will lead a joint collaboration between the laboratories of Don Nguyen and Katerina Politi, and will further participate in a multi-disciplinary research within the NCI’s Patient-derived models of cancer consortium, the Yale SPORE in lung cancer and additional collaborators. More information can be found at http://medicine.yale.edu/lab/nguyen/ and https://medicine.yale.edu/lab/politi/.

Applicants should recently hold or be nearly completing a PhD or MD/PhD degree in the biological sciences, genomics, or related field. Candidates with experience in one or more of the following areas are encouraged to apply:
 

  • Epigenomics
  • Cancer biology
  • Animal models of disease
  • Tumor microenvironment

Interested applicants should direct their CV, a brief statement of research interests, and arrange for three letters of recommendation to be sent to Wendy Folsom  (wendy.folsom@yale.edu.)

Yale University is an Afirmative Action/Equal Opportunity employer. Our laboratories value diversity among our students, staff, and faculty and we strongly welcome applications from women, persons with disabilities, and underrepresented minorities.

Katerina Politi, PhD
Associate Professor
Department of Pathology and Internal Medicine (Section of Medical Oncology)

Co-leader Cancer Signaling Networks Program
Yale Cancer Center
Yale University School of Medicine
333 Cedar Street, SHM-I 234D
New Haven, CT 06510 USA
 

Don X. Nguyen, Ph.D

Associate Professor

Yale University School of Medicine

Department of Pathology

Assistant Cancer Center Director for Research Development

Yale Cancer Center

Brady Memorial Laboratory

P.O. Box 208023

New Haven, Connecticut, 06520-8023

Postdoctoral position Oktay Laboratory, Department of Obstetrics, Gynecology & Reproductive Sciences
Posting Date: August 20, 2021

To understand the background of the Oktay laboratory’s theme, please refer to our recent publications in Science Translational Medicine, Scientific Reports and Journal of Clinical Oncology.   

  1. Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans.Titus S, Li F, Stobezki R, Akula K, Unsal E, Jeong K, Dickler M, Robson M, Moy F, Goswami S, Oktay K. Sci Transl Med. 2013 Feb 13;5(172):172ra21. doi: 10.1126/scitranslmed.3004925
  2. Turan V, Lambertini M, Lee DY, Wang E, Clatot F, Karlan BY, Demeestere I, Bang H, Oktay K. Association of Germline BRCA Pathogenic Variants With Diminished Ovarian Reserve: A Meta-Analysis of Individual Patient-Level Data. J Clin Oncol. 2021 Jun 20;39(18):2016-2024. doi: 10.1200/JCO.20.02880. Epub 2021 Apr 23. PMID: 33891474; PMCID: PMC8260903
  3. Titus S, Szymanska KJ, Musul B, Turan V, Taylan E, Garcia-Milian R, Mehta S, Oktay K. Individual-oocyte transcriptomic analysis shows that genotoxic chemotherapy depletes human primordial follicle reserve in vivo by triggering proapoptotic pathways without growth activation. Sci Rep. 2021 Jan 11;11(1):407. doi: 10.1038/s41598-020-79643-x. PMID: 33431979; PMCID: PMC7801500.).

Education:  Leading NIH-funded laboratory in ovarian biology, aging, and fertility preservation is looking for a postdoctoral candidate with strong background in molecular biology. Experience with single-cell qRT-PCR and RNA sequencing, epigenomics, bisulfite sequencing techniques will be preferred. Interpersonal skills will be highly important as this is a multidisciplinary translational project.

Training:  The Postdoctoral Fellow will train and work on the role of DNA repair in oocyte aging as well as the relationship of BRCA and related mutations to reproductive and overall aging.

Mentoring:  Mentorship is provided by Kutluk Oktay, MD, PhD, Principal Investigator.

Those who feel strongly qualified can email a cover letter and a CV to Colleen.Goble@Yale.edu, Faculty & Staff Affairs Manager, Department of Obstetrics, Gynecology, and Reproductive Sciences.

Postdoctoral position in Cancer Biology(Sheltzer Lab)
Posting Date: August 29,2021

The Sheltzer Lab at Cold Spring Harbor is seeking postdoctoral researchers for a funded project identifying novel cancer drug targets.

Our laboratory is using CRISPR mutagenesis to uncover unique cancer “dependencies” and to

characterize the mechanism-of-action of different anti-cancer agents. Unexpectedly, we have found that many drugs used in human patients have been designed to target proteins that are non-essential for cancer proliferation. Moreover, we’ve demonstrated that these drugs necessarily act by inhibiting some other offtarget protein(s).

We are applying a combination of techniques, including CRISPR screens, targeted mutagenesis, live-cell microscopy, and molecular pharmacology, to study a variety of cancer drugs and to figure out how they actually work. Through these approaches, we have found that one mis-characterized drug functions by targeting the cyclin-dependent kinase CDK11B – the first inhibitor of this kinase to be discovered. This finding sheds light on a poorly-studied cell cycle regulator and unlocks an entirely new target for cancer drug development. We are seeking to both learn more CDK11B’s function in cancer and to apply similar approaches to characterize other small molecule drugs. By discovering the true mechanism-of-action of mis-characterized inhibitors, we hope to identify biomarkers that can be used to accurately predict patient sensitivity and to monitor drug efficacy in vivo.

More information can be found in our publications, including:

Lin A., and Sheltzer J.M. (2020). Discovering and validating cancer genetic dependencies: approaches and pitfalls. Nature Reviews Genetics. doi:10.1038/s41576-020-0247-7.

Lin, A., Giuliano, C.J., Palladino, A., John, K.M., Abramowicz, C., Yuan, M.L., Sausville, E.L.,

Lukow, D.A., Luwei, L., Chait, A.R., Galluzzo., Z.C., Tucker, C., Sheltzer, J.M. (2019). Off-target

toxicity is a common mechanism-of-action of cancer drugs undergoing clinical trials. Science

Translational Medicine. 11, eaaw8412.

The Sheltzer Lab is a highly-collaborative environment that values rigorous research and that welcomes scientists from all backgrounds. We are located at Yale University, an internationally-renowned research university located in the historic city of New Haven, Connecticut. Yale has long been recognized as an outstanding environment for nurturing young scientists, with postdoctoral researchers being an integral part of the discovery process.

Additional information on research in the Sheltzer Lab can be found on our website: www.sheltzerlab.org.

Candidates who are interested in applying to this position should send a CV and cover letter to Dr. Sheltzer at Jason.Sheltzer@yale.edu.

Postdoctoral Associate position in the DNA Diagnostics Laboratory, Department of Genetics
Posting Date: August 17, 2021

The DNA Diagnostics Laboratory seeks highly motivated candidates for a position in cutting-edge translational human genomics.  The focus of this laboratory is application of high-throughput DNA and RNA sequencing technology for diagnosis of human disease.  Elements of this position include:

  • Learning to interpret whole-exome and whole genome sequence data from patients with hereditary disorders including gaining skills with human-genetics databases, reviewing medical literature to identify and summarize evidence of pathogenicity for genetic variants, and becoming familiar with medical standards of care in reporting genetic tests to health care providers and patients
  • Helping to assure accurate and efficient operation of the laboratory in the context of quality control regulations that guide clinical laboratories (e.g., CLIA)
  • Participation in the development and validation of software for variant interpretation
  • Independent development of new wet-lab or bioinformatic technologies for applications such as clinical use of RNAseq, long-read genomic sequencing, and epigenetic analysis.

Applicants must have a PhD and/or MD degree in genetics or bioinformatics with experience in human genetics.  Clear, concise written and oral communication with a multidisciplinary team will be an essential part of this job. Successful candidates should have keen organizational skills, attention to detail, and ability to work efficiently to complete projects within assigned deadlines.  This position provides an excellent background to those interested in a future fellowship in Laboratory Genetics and Genomics. 

Candidates should send a Curriculum Vitae, a personal statement of relevant background and future plans, and three references (include names / contact information) to: hui.zhang@yale.edu and allen.bale@yale.edu

Postdoctoral Position in Neuroscience (Kim Lab)
Posting Date: August 16, 2021
The Kim Laboratory at Yale University School of Medicine is inviting applications for two postdoctoral positions to investigate mechanisms regulating subcortical circuit formation. We are focusing on the assembly of the neural circuitry mediating visual threat-triggered defensive behavior. Our research methodology includes mouse genetics, AAV-mediated neurocircuit analysis, bioinformatics, confocal microscopy, and behavioral tests. The ultimate goal of the project is to define molecular mechanisms that underlie development of previously unexplored visual circuits and regulate their functions in fear-related behavioral responses.
 
The ideal candidate would have a background in neuroscience, molecular genetics, cell biology, or a related field. Previous experience in molecular biology and histology is required. Familiarity with mouse models, in vivo surgery, and behavioral testing would be a plus.
 
Interested candidates should e-mail their applications directly to in-jung.kim@yale.edu. The application should include: (1) CV with a full publication list; (2) Brief description of research interests; (3) Contact information for 2-3 references.
Postdoctoral position in the Department of Neurology (Kim Lab)
Posting Date:

The Division of Neurocritical Care in the Department of Neurology at Yale University is inviting applications for a two-to-three-year postdoctoral position with experience in one or more of the following: physiologic signal processing (e.g., EEG), image processing and machine learning methods. The applicant would be joining the lab of Dr. Jennifer A. Kim MD-PhD, which focuses on predicting complications and poor outcomes after acute brain injuries injuries, such as trauma, stroke or brain hemorrhage, using data from multiple diagnostic modalities.

The main goal of the research will be development of signal processing and/or image processing and machine learning methods for prediction of complications and poor outcomes after acute brain injury. The position will require both the processing of already collected datasets as well as assistance with the ongoing effort of establishing a larger data set of recordings and images, which may include some practical implementation, execution, storage, and transfer of new data.

Applicant must have a background in signal processing, or image processing and some experience in statistical modeling or machine learning methods. Programming experience in Matlab, Python and/or R is a prerequisite. Experience with EEG, other brain physiology recordings and/or MRI analyses is an advantage but not required. Experience with a range of machine learning methods including random forest and deep learning methods also an advantage, but not required.

Good oral and written English communication skills, the ability to work both independently and as part of a team, is a prerequisite. Candidates must be self-motivated. Responsibilities will include design, implementation and dissemination of research including data processing, modeling, and drafting manuscripts.

This appointment as a postdoctoral researcher requires academic qualifications at the PhD or MD level, preferably in Computational Neuroscience, Engineering, Bio/Statistics, Computer Science, or related areas.

To apply: Please send an email with your CV, contact information for 3 references, and cover letter to: Sara.jasak@yale.edu

Postdoctoral position in Human Evolutionary Genomics(Tucci Lab)
Posting Date: August 9, 2021

The Tucci lab at Yale University invites applications for Postdoctoral Research Associate positions. Our research addresses fundamental questions in Human Evolutionary Genomics by using field work, laboratory work, and cutting-edge computational approaches to disentangle the evolutionary forces that have shaped patterns of genetic variation in human populations.

Responsibilities:

A successful candidate will develop and use statistical frameworks to analyze large-scale genomic data sets to reconstruct the evolutionary history of modern and ancient human populations (as well as human and non-human primates) and to gain insights into genetic adaptations.

Expected responsibilities include conducting research, attending weekly lab meetings, participating to scientific journal clubs, preparing research findings for publication and presenting reports at professional meetings. Opportunities exist for mentoring graduate and undergraduate students.

Qualifications

  • PhD in Evolutionary Biology, Computational Biology, Population Genetics, Statistics, Biostatistics, Computer Science, Biological Anthropology, or disciplines with strong quantitative backgrounds
  • Strong programming and bioinformatics skills (R, Python Perl, or C/C++, Bash scripting, cluster computing,etc)
  • Research experience in population genetics analyses and working with large sequencing data sets.
  • Strong background in statistical inference
  • Independent, motivated, creative, and collegial
  • Strong writing skills.

Salary and duration

 The initial appointment is for one year, renewable annually up to three more years, pending satisfactory performance and continued funding. Salary is commensurate with qualifications and experience. Flexible start date in Fall 2021 or Spring 2022.

Applications must be submitted online at: tucci.serena@gmail.com and will be reviewed until the positions are filled.

Applications should include:

  • A curriculum vitae
  • A list of publications (for each publication please add a brief description of your contribution).
  • A brief statement of research interests and goals
  • A 2-page research proposal
  • Names and contact information for three references.

Informal inquiries are welcome. Please contact Principal Investigator Serena Tucci at serena.tucci@yale.edu

Postdoctoral position in Behavioral Neuroscience (Girgenti Lab)
Posting Date: August 4, 2021

The Girgenti Laboratory at Yale University is recruiting a behavioral neuroscience post-doctoral position, available in the fall.

Research in the Girgenti lab is directed at determining the molecular pathologies underlying stress disorders such post-traumatic stress disorder (PTSD), major depressive disorder (MDD), and suicidal behavior. We are looking for an enthusiastic and motivated postdoctoral researcher to take a key role in planning and executing both behavioral and basic neuroscience experiments. Major projects in the lab include translational neuroscience projects designed to derive biological meaning from large-scale genomic findings and characterize the behavioral and molecular mechanisms of stress disorders. Trainee-led projects are also encouraged, and there are ample opportunities for growth in the lab and at Yale.  We have world class collaborations locally, nationally, and abroad to support an exciting and rich training experience. Please reach out if you have any questions.

Required Qualifications

  • A Ph.D. and relevant research experience in neuroscience or related fields (e.g. Biological Psychology, Behavioral Neuroscience, Pharmacology).
  • Highly organized and extremely reliable.
  • Prior experience working with mice and rats and conducting behavioral studies, and also have technical experience with rodent surgery (e.g. stereotaxic, catheterization). Special consideration will be given to those with experience in behavioral models of chronic and traumatic stress and anxiety.

To apply:

Please send an email with your CV, contact information for 3 references, and cover letter to: Dr. Matt Girgenti (matthew.girgenti@yale.edu) using the subject line: Postdoctoral applicant: Your name. Applicants are encouraged to outline research projects of interest.

More information about our labs can be found at: https://medicine.yale.edu/profile/matthew_girgenti/.

Postdoctoral position in Psychiatric Genomics(Girgenti Lab)
Posting Date: August 4, 2021

The Girgenti Laboratory at Yale University is recruiting a molecular neuroscience post-doctoral position, available in the fall.

Research in the Girgenti lab is directed at determining the molecular pathologies underlying stress disorders such post-traumatic stress disorder (PTSD), major depressive disorder (MDD), and suicidal behavior. We are looking for an enthusiastic and motivated postdoctoral researcher to take a key role in planning and executing experiments identifying functional genomic elements of neuropsychiatric disorders in human postmortem brain tissue by using single cell gene expression and chromatin approaches, RNAscope, ChIP-seq and HiC assays. Major projects in the lab include translational neuroscience projects designed to derive biological meaning from large-scale genomic findings and postmortem genomic approaches to dissect epigenetic and cell-type-specific regulatory elements underlying the genetics of stress-related mental disorders. Trainee-led projects are also encouraged, and there are ample opportunities for growth in the lab and at Yale.  We have world class collaborations locally, nationally, and abroad to support an exciting and rich training experience. Please reach out if you have any questions.

Required Qualifications

  • A Ph.D. and relevant research experience in neuroscience or related fields (e.g. molecular biology or molecular neuroscience).
  • Highly organized and extremely reliable.
  • Prior experience working with postmortem brain tissue and genomic assays such as RNA- and ATAC-seq, RNAscope (or equivalent FISH assay).  Special consideration for candidates with experience in single cell type genomics assays.

To apply:

Please send an email with your CV, contact information for 3 references, and cover letter to: Dr. Matt Girgenti (matthew.girgenti@yale.edu) using the subject line: Postdoctoral applicant: Your name. Applicants are encouraged to outline research projects of interest.

More information about our labs can be found at: https://medicine.yale.edu/profile/matthew_girgenti/.

Postdoctoral position in the Department of Psychology
Posting Date: August 3, 2021

The Yale Psychology Department is pleased to announce a postdoctoral scholar position in honor of Professor Susan Nolen-Hoeksema that has been endowed by her husband, Richard Nolen-Hoeksema. The Susan Nolen-Hoeksema Postdoctoral Associate in Integrative Psychology is for a two-year period. Eligible applicants must have a PhD in Psychology or a related field by June 30 of the year in which the appointment begins. Applications in any area of psychology are encouraged, especially from candidates with research interests that are integrative across areas and levels of analysis and applicable to one or more domains of psychopathology or its treatment (i.e., areas in which Professor Nolen-Hoeksema took special interest).

Applicants for the position, to begin July 1, 2022, should identify one or more Yale faculty member(s) with whom they desire to work during the term of the appointment, and include a personal statement, curriculum vitae, reprints of selected papers, and letters of recommendation from two to three individuals familiar with the applicant’s research background and promise. Review of applications will begin on December 1, 2021 and continue until the position is filled.

Applications should be submitted via Interfolio: http://apply.interfolio.com/90895

For questions please contact Jessica Hermann, Senior Administrative Assistant, Jessica.hermann@yale.edu

 

Postdoctoral position to Study Circuits Underlying Social Behavior Development (Che Lab)
Posting Date: August 3, 2021

The Che lab at Yale Psychiatry (thechelab.org) is looking for a highly motivated individual to join a young and vibrant research group, and lead the project studying how early-life tactile experience contribute to the development of social behaviors. The postdoctoral associate will develop and apply in vivo imaging techniques in combination with behavioral testing to elucidate the effects of early-life experiences. This will be combined with the lab’s expertise in using two-photon imaging tools, circuit mapping, electrophysiology and mouse genetics to generate a multi-dimensional dataset. The postdoctoral associate is expected to bring these aspects together in an impactful project.

An ideal candidate will have background in in vivo imaging and image processing, animal behavior, advanced data analysis and in-depth knowledge of a programing language, or bioengineering.

Interested applicants should send a CV, research interests and accomplishments, names and contact information of three references to Dr. Alicia Che (alicia.che@yale.edu).

Postdoctoral position in Cancer Biology and Genetics (Wilson Lab)
Posting Date: July 30, 2021

The Wilson laboratory in the Section of Medical Oncology and the Yale Cancer Center is seeking highly-motivated candidates for a postdoctoral position.  Interests in the laboratory focus on identifying and characterizing genetic vulnerabilities in cancer and molecular mechanisms of drug resistance with an emphasis on lung cancer therapeutics (https://medicine.yale.edu/bbs/people/frederick_wilson-1.profile). The lab leverages genome-scale CRISPR-based functional genomic screening platforms to identify genetic cancer vulnerabilities and to dissect resistance mechanisms in relevant cancer cell models.  The lab also applies DNA- and RNA-based next-generation sequencing technologies to identify candidate driver gene alterations and other potentially actionable genomic features from patient tumor specimens.  Mechanistic studies are then leveraged in cell model systems to assess the functional impact of identified genetic alterations.  A major priority is to translate laboratory findings into therapeutic strategies for patients with advanced lung and other cancers.

A major emphasis in the laboratory is to provide scientific mentorship through regular meetings with the principal investigator and opportunities for professional development in a supportive and collaborative environment.  An important goal is for the postdoc to generate a body of scientific work leading to a first-author peer-reviewed publication.
 
Applicants must have experience in molecular biology, genetics / genomics, cancer biology, or other related field in the biological sciences.  The candidate must have a recent PhD or MD/PhD degree in a relevant field with a proven track record of scientific productivity including at least one first author publication in a peer-reviewed journal.  Excellent written and oral communication skills are expected.  The candidate will be expected to work independently in the design and execution of experiments with guidance from the principal investigator.  As projects in the laboratory are often highly collaborative, the candidate should be able to work effectively and enthusiastically in a team environment.
 
Candidates should send a Curriculum Vitae, a statement of research interests and career goals, and names / contact information for three references to: frederick.wilson@yale.edu.
 

Postdoctoral position in Neuroinfectious Disease (Farhadian Lab)
Posting Date: July 26, 2021

The Farhadian Lab, in the division of Neuroinfectious Diseases, seeks a postdoctoral associate. Our group studies brain effects of systemic infections through translational studies of diseases including HIV, COVID-19, lyme disease, and syphilis. We seek a post-doctoral associate to join our team to use approaches including single cell RNA sequencing and mass cytometry, to understand the roles of host immune activity and viral persistence in contributing to the brain effects of these and other infections. 

We specifically seek applicants with background/interest in transcriptomics, bioinformatics, and/or immunology. Depending on the candidate, there are opportunities to contribute to computational or wet-lab projects.

The Farhadian lab is led by Dr. Shelli Farhadian, a physician-scientist with expertise in neuroinfectious diseases. Our studies focus on curated cohorts of patients with acute neurological infections and are supported by the NIH and others. We collaborate with labs in computational biology (Kleinstein and Kluger labs), Neurology (Spudich lab), and others in the Departments of Medicine, Neurology, and Immunobiology, and at the School of Public Health. Dr. Farhadian emphasizes strong mentorship and working with each member of the lab to achieve their career goals. More information can be found here: https://medicine.yale.edu/profile/shelli_farhadian/

Qualifications

  • MD and/or PhD with research experience in immunology or computational biology
  • Experience with RNAseq and/or experience with basic molecular and immunology techniques (flow cytometry; cytof) is a plus

Please email statement of interest, C.V., and names of two references to shelli.farhadian@yale.edu. In the subject line, please write “Your Full Name, Postdoc application”.

Postdoctoral position with the Center for Outcomes Research and Evaluation (CORE)
Posting Date: July 23, 2021

The Yale/Yale New Haven Hospital Center for Outcomes Research and Evaluation (CORE) is a leading national outcomes research center dedicated to transforming healthcare for the betterment of people and society by leveraging data, analytics, and technology. We have assembled a talented, multidisciplinary group who are committed to developing solutions to the practical needs of medicine and healthcare. Our organization combines the highest academic ideals with a pragmatic approach that emphasizes the production of useful knowledge. We are distinguished by our creativity, dedication, experience, and skills – and our commitment to having our work make a tangible difference to patients, the public, and society. For additional information on CORE, please visit our website: www.medicine.yale.edu/core.

CORE is recruiting a Postdoctoral Associate for its ongoing research program in computational health. The program is recruiting candidates with coding experience in Python and R, with a specific background in analytics on large relational datasets and the electronic health record (EHR). The specific skills include masters or doctoral training in computer science/informatics with an understanding of basics of informatics, and distributed computing with Spark (using Python or R). Successful candidates will participate in a range of research projects spanning various disease conditions with the opportunity to work with leading investigators in the space working on the next generation of knowledge generation in medicine. Career development will be supported through scholarly contributions, including research publications and presentations at national meetings. A PhD or equivalent is a requirement for this position; a background in healthcare analytics is preferred, but not required. The position is currently being offered for 2 years, with the option for extending beyond that time. The renumeration for the position is in line with Yale’s institutional standards.

Interested applicants should send a brief statement of interest and curriculum vitae with contact information for three references to kendall.getek@yale.edu.

Postdoctoral position in Omics of Psychiatry (Levey Lab)
Posting Date: July 23, 2021

Postdoctoral position for a highly motivated graduate student to join the Yale Psychiatry Division of Human Genetics, a productive and collaborative research environment with a focus on the genetics of psychiatric illnesses, behavioral phenotypes, and other complex traits founded by Dr. Joel Gelernter. The successful candidate will work with Dr. Daniel Levey on projects funded by the Brain & Behavior Research Foundation and the U.S. Department of Veterans Affairs, investigating the genetics of depression and anxiety disorders and related psychiatric traits in the VA Million Veteran Program dataset (one of the world’s largest and most informative biobanks) and the Psychiatric Genomics Consortium (the largest experiment in the history of biological psychiatry). Additional opportunities will include the analysis of a growing sample in the deeply phenotyped Yale-Penn cohort with genetics, RNAseq, and epigenetic data. Collaborations with other investigators within the division will be strongly encouraged.

Applicants must have or be about to be awarded a Ph.D. and/or M.D. The ideal candidate will have a strong background in human genetics or transcriptomics, including knowledge of genome-wide methods or RNAseq, including GWAS and downstream in-silico analyses and comfort with bioinformatics. The candidate should also be able to work cooperatively with peers at Yale and with many other collaborators nationally and internationally, and bring research to publication. The start date is flexible.

Please send your application (including CV and contact information for three references) by email to Dr. Levey at daniel.levey@yale.edu<mailto:daniel.levey@yale.edu> with Postdoctoral Associate in the title.

Postdoctoral position in Psychiatric Genetics (Gelernter Lab)
Posting Date: July 23, 2021

A postdoctoral position is available for a highly motivated graduate student to join a productive and collaborative research group working on the genetics of psychiatric illness – especially PTSD and substance use disorders. Work will focus on (1) genetics of posttraumatic stress disorder, depression and anxiety, substance use disorders, and many related psychiatric traits in the uniquely-informative Million Veteran Program dataset; and (2) Psychiatric Genomics Consortium projects including these traits, and (3) studies in non-European populations. Through these and several other current projects, we explore large datasets including the Million Veteran Program and the Psychiatric Genomics Consortium. Other projects include a pharmacogenomics clinical trial for depression taking place in the VA system; a study of methamphetamine genetics in Thailand; a new mental health biobank project in the MVP; and studies of epigenetics of psychiatric traits.

The ideal candidate should hold an MD or PhD, and have a strong background in human genetics, including knowledge of genomewide methods, including GWAS and post-GWAS analysis; and comfort with bioinformatics. The candidate should also be able to work cooperatively with peers at Yale and with many other collaborators nationally and internationally; and bring research to publication. Faculty in our closely-collaborative division at Yale School of Medicine includes Drs Renato Polimanti, Janitza Montalvo-Ortiz, and Daniel Levey. Start date is flexible. Applicants should preferably have US citizenship or permanent residency.

Please send application (including CV and contact information for at least three references) by email to Prof. Joel Gelernter at joel.gelernter@yale.edu<mailto:joel.gelernter@yale.edu>

Postdoctoral position in Wildlife Molecular Ecology at Yale University
Posting Date: July 16, 2021

The Applied Wildlife Ecology (AWE) Lab in the Yale School of the Environment invites applications for a Postdoctoral Associate in Wildlife Molecular Ecology. The successful candidate will assist with protocol develop and implication leverage existing carnivore fecal samples as well as future collected soil and snow samples to understand spatial and temporal variation in prey consumption and availability. This work contributes to a new National Science Foundation-funded project (#2140322) on risk management in Detroit coyotes under the supervision of Prof. Nyeema C. Harris. At the frontier of behavioral and urban ecology, results from this project will garner new insights on how resources govern risk assessment, discrimination, and mitigation in apex predators living in cities where 81% of US residents live.

The ideal candidate has a Ph.D. focusing on topics in molecular ecology with exceptional research, writing, and verbal communication skills as well as an inclusive and flexible approach to collaborating with a diverse team of individuals and organizations. Experience with next-generation sequencing, metabarcoding, and eDNA are required. This is a one-year position with an expected reappointment for two additional years upon outstanding performance. The hire will be expected to perform sample processing and molecular analyses, co-author papers, mentor students, and contribute to public engagement and efforts to broaden participation. In addition to a competitive salary and full research support, the successful candidate will receive an annual professional development budget for additional trainings and scouting trips for future research based on their interests.

Yale values diversity among its students, staff, and faculty and strongly encourages applications from minoritized people especially BIPOC scholars and persons with disabilities. Consideration of applicants will begin immediately with the start date negotiable between September 2021 - January 2022.

Interested candidates should email a cover letter and their CV (hyperlink publications) along with a contact list of at least three references and “Coyote Molecular Postdoc” in the subject line to Nyeema C Harris, PhD, Associate Professor of Wildlife and Land Conservation at nyeema.harris@yale.edu.

 
Postdoctoral position in the Department of Neuroscience (Liang Lab and Crair Lab)
Posting Date: July 9, 2021

We are looking for a postdoctoral associate to join a collaborative project between the laboratories of Dr. Liang Liang and Dr. Michael Crair in the Department of Neuroscience at Yale School of Medicine. The project will focus on understanding how neural activity contributes to the establishment of thalamic visual function during development. The Liang lab has established an advanced in vivo imaging platform for studying the detailed functional and spatial organization of the visual thalamus in adult mice. The Crair lab has extensive experience imaging and manipulating neural activity in early postnatal mice, and has identified characteristic spatiotemporal patterns of retinal activity that guide neural circuit development. The postdoctoral associate is expected to bridge strengths from both labs to unveil the mechanisms underlying the development of functional selectivity in the early visual system. This position is funded by a Kavli Institute Innovative Research Award. The candidate is expected to lead the project and will be co-mentored by Dr. Liang Liang and Dr. Michael Crair.

An ideal applicant will be someone who can demonstrate the following:

Essential

  • The candidate should be in his/her last year of a PhD program in Neuroscience, Biology or related field, or within 1 year of receiving his/her PhD degree. 
  • An outstanding record of research and scholarly activity.
  • A demonstrable commitment to scientific discovery.
  • Be creative, thoughtful, strongly self-driven and well organized.
  • Have skills and experience in advanced neurophysiological techniques and quantitative data analysis.
  • Have skills and experience with complex surgery in model organisms.

Desirable

  • A good track record of securing fellowship and research funding.
  • In-depth knowledge of a programing language.
  • A good knowledge of the visual system.
  • Have skills and experience in two-photon calcium imaging and image processing

Interested candidates should contact Dr. Liang Liang (liang.liang@yale.edu) and Dr. Michael Crair (michael.crair@yale.edu). The application should include: (1) CV; (2) A brief description of research interests and motivation; (3) Contact information for 3 references.

Postdoctoral position in innate immunity and host-virus interactions (Foxman Lab)
Posting Date: July 7, 2021

The Foxman lab at the Yale School of Medicine is seeking postdoctoral researchers to join our team investigating innate immunity, host-virus interactions, and post-injury tissue repair in the human respiratory tract. Our lab spans the basic to translational spectrum, using patient samples, primary human cells, and organoid models, and techniques such as transcriptomics, proteomics, and single cell RNA Seq.  Background/interest in the following areas a plus: immunology, virology, next generation sequencing, single cell analysis. For more information about our recent work on host-virus interactions in the human respiratory tract, including studies of rhinovirus, influenza, and SARS-CoV-2, see our lab website at https://medicine.yale.edu/lab/foxman/.  

Our lab is in the Yale Department of Laboratory Medicine, and is affiliated with the Yale Department of Immunobiology, affording candidates access to a large network of colleagues doing exciting research and outstanding career development opportunities such as participation in departmental retreats, research in progress talks, and career development programming.  Dr. Foxman is also deeply committed to professional development and creating a plan that enables each post-doc to reach their career goals.

Please email statement of interest, C.V., and names of three references to ellen.foxman@yale.edu.

Requirements: PhD, MD, or MD/PhD and relevant training and publication record.

Forest Carbon in Southern New England Postdoctoral Associate
Posting Date: July 6, 2021
The Forest School at The Yale School of the Environment (YSE) invites applications for a Postdoctoral Associate in Forest Carbon. The successful candidate will assess forest carbon dynamics as they relate to natural disturbance and forest products, with a focus on southern New England. The candidate will work under the mentorship of faculty at The Forest School within YSE, and data from the Yale Forests and Great Mountain Forest will be available. Professors Mark Bradford and Yuan Yao will jointly serve as the primary supervisors, and other faculty at The Forest School will serve as collaborators.
 
The forests of southern New England have received significant attention in recent years for their potential as nature-based climate solutions. However, the carbon dynamics of these forests are highly complex and influenced by past land use, stand dynamics, invasive species, changing climate, and carbon tradeoffs related to forest products. Political debate has often simplified to two alternatives: active management and no management, yet the reality is far more complex. The person in this position will investigate the risks and longevity of carbon stored in forests and forest products in the region in the context of changing forests.
 
Results of this project will include peer-reviewed publication(s) and policy briefs related to carbon stability in southern New England’s forests as it relates to disturbance, stand dynamics, and management. The successful candidate will also investigate the carbon tradeoffs of local forest products and lead the development of best management practices for carbon as a management objective in southern New England forests, while working with a collaborative team of faculty and graduate students at The Forest School focused on forest carbon. We expect this research will better our understanding of the climate mitigation and adaptation of regional forests.
Support for this postdoctoral position comes from the Joseph Steven Taylor Fund at YSE.
 
The position is a one-year appointment with the possibility of two additional years of renewal contingent upon satisfactory performance and availability of funding. Candidates who have a Ph.D. degree in forestry or related fields with peer-reviewed publications related to silviculture and/or forest carbon and statistical modeling/ life-cycle assessment are highly encouraged to apply.
 
Consideration of applicants will begin immediately, but applications will be accepted until July 30, 2021. The start date of the position is negotiable, with a target of September 1, 2021.
 
Interested candidates should email a cover letter and their CV, along with a list of at least three references to Mark Bradford at mark.bradford@yale.edu
 
Application Deadline: July 30th 2021
Anticipated Start Date: September 1st 2021
Postdoctoral position at the School of Public Health (Aksoy Lab)
Posting Date: July 6, 2021

We are inviting motivated Postdoctoral Scientists to join our group to study the physiology, and the molecular and genetic mechanisms involved in host-pathogen interactions in the tsetse fly-African trypanosome system. We study the role of the fly immune system and the influences of tsetse’s endosymbiotic bacteria in the parasite infection process.  We also investigate parasite mediated mechanisms that modify tsetse’s vector competence efficiency and influences the transmission success of trypanosomes to the next mammal in fly saliva. Finally, we are developing transmission blocking vaccines that target antigens present on the parasites in saliva that are deposited to the mammalian bite site.

We are looking for highly motivated scientists trained in a related field such as entomology, microbiology or immunology.  Our lab provides a collaborative environment and multi-disciplinary training for scientific and career development. Our lab has a track record of training postdoctoral researchers: our postdocts have international conference presentations and first authored original articles in high impact journals. We also have extensive international collaborations with researchers in Africa which provide a rich training environment for our researchers in global health.

The successful candidate will likely have (a) a recent (,4-years) PhD degree in entomology, microbiology or immunology or a related discipline; (b) a track record of research productivity , as evidenced by first authored original publications in high quality peer-reviewed journals; (c) experience in–omics based technologies, and parasite or insect cultures; (d) experience with BSL2 procedures; (e) independence to lead a project as well as willingness to work in a team; (f) an open mind to learn new methods from collaborators and (g) good scientific presentation and writing skills. Previous experience in immunology, parasitology and bioinformatics are preferred. Salary and benefits are according to Yale and NIH guidelines.

Interested candidates may send a CV, personal statement and contact information for three references to Serap Aksoy (serap.aksoy@yale.edu).  Interested candidates can obtain additional information on our work https://ysph.yale.edu/profile/serap_aksoy/.  Below are a few of our recent publications.

1. Aksoy E, Vigneron A, Bing X, Zhao X, O’Neill M, Wu YN, Bangs JD, et al. (2016) Mammalian African trypanosome VSG coat enhances tsetse’s vector competence. Proc Natl Acad Sci U S A 113: 6961-6966.

2. Bing X, Attardo GM, Vigneron A, Aksoy E, Scolari F, Malacrida A, Weiss BL, et al. (2017) Unravelling the relationship between the tsetse fly and its obligate symbiont Wigglesworthia: transcriptomic and metabolomic landscapes reveal highly integrated physiological networks. Proc Biol Sci 284.

3. Vigneron A, O’Neill MB, Weiss BL, Savage AF, Campbell OC, Kamhawi S, Valenzuela JG, Aksoy S. Single-cell RNA sequencing of Trypanosoma brucei from tsetse salivary glands unveils metacyclogenesis and identifies potential transmission blocking antigens. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2613-2621.

4. Michalkova V, Benoit JB, Weiss BL, Attardo GM, Aksoy S (2014) Vitamin B6 generated by obligate symbionts is critical for maintaining proline homeostasis and fecundity in tsetse flies. Appl Environ Microbiol 80: 5844-5853.

5. Weiss BL, Savage AF, Griffith BC, Wu Y, Aksoy S (2014) The Peritrophic Matrix Mediates Differential Infection Outcomes in the Tsetse Fly Gut following Challenge with Commensal, Pathogenic, and Parasitic Microbes. J Immunol 193: 773-782.

6. Vigneron A, Aksoy E, Weiss BL, Bing X, Zhao X, Awuoche EO, O’Neill MB, et al. (2018) A fine-tuned vector-parasite dialogue in tsetse’s cardia determines peritrophic matrix integrity and trypanosome transmission success. PLoS Pathog 14: e1006972.

7. Weiss BL, Wang J, Maltz MA, Wu Y, Aksoy S. Trypanosome infection establishment in the tsetse fly gut is influenced by microbiome-regulated host immune barriers. PLoS Pathog. 2013;9(4):e1003318.

Postdoctoral position in Human Systems Immunology(Konnikova)
Posting Date: June 27, 2021

Research in the Konnikova group is directed at studying the development and maintenance of mucosal immunity at barrier sites such as the intestine and placenta. We are interested in understanding how homeostasis is established and maintained in humans and what goes awry to cause disease such as necrotizing enterocolitis and inflammatory bowel disease in relationship to intestinal health and preterm labor in case of placental biology. We are seeking a motivated and dynamic postdoctoral candidate to join our team who is interested in applying cutting edge techniques including mass cytometry and single cell RNA sequencing in combination with cell biology and organoid approaches to studying development of human mucosal immunity at barrier sites. My group has access to the CyTOF and genomics cores at Yale as well as state-of-the-art cell and molecular imaging facilities. During this time, the successful applicant will obtain further training in translational research, in vivo model systems and a range of immunological techniques.

The candidate will be expected to have an MD, PhD, or MD/PhD with experience in immunology. Preference to candidates with involvement in human immunology will be given, but it is not a requirement. The successful candidate will be self-motivated and have the capacity for independent evaluation of the literature. Prior knowledge in primary cell isolation, flow cytometry, imaging techniques and single cell techniques would be an added benefit. For more information on our group, please visit our website – www.konnikovalab.com.

Interested applicants should send a brief statement of interest and curriculum vitae with contact information for three references to the Principal Investigator, Dr. Liza Konnikova – liza.konnikova@yale.edu.

Wu Tsai Postdoctoral Fellowship
Posting Date: June 23, 2021

Come join a community dedicated to understanding the mind and cognition through integration across disciplines, organisms, and scales.

The Wu Tsai Postdoctoral Fellowship program at Yale seeks scientists who are excited about frontiers in interdisciplinary neuroscience and who represent a diversity of identities, including those from historically underrepresented backgrounds in science.

Apply to one of four priority co-mentored projects, carefully selected for their science and inclusive and supportive training environments, or submit an application to our open track.

Fellows receive:

  • Competitive stipend ($60,000), health benefits, and discretionary training funds for a maximum of three years, upon annual review
  • Cohort-based professional development and community-building activities
  • Access to cutting-edge facilities at the new Wu Tsai Institute

Eligibility:

  • PhD degree or equivalent, awarded within past three years
  • Track record of discoveries and demonstrated level of scientific independence appropriate for a beginning postdoc
  • Self-identifying as being a member of a group underrepresented science. and/or demonstrated commitment to fostering diversity, equity, and inclusion.
  • Interdisciplinary orientation
  • International applicants welcome
  • Current Yale postdocs and PhD students are not eligible to apply

Deadline for applications is August 15.

To apply and for more info see: https://bit.ly/WTIPostdocFellows

Priority areas include:

  • Uncovering the molecular basis of neuroticism, a fundamental personality trait - Explore the effect neuroticism-associated DNA variants on gene expression and develop massively parallel reporter assays to test effects on neural systems. Applicants should have expertise in stem cell biology, neuroscience, massively parallel reporter assays, high-throughput CRISPR genomic manipulations, and/or statistical genetics and epigenetics, and be interested in bridging computational and experimental approaches.
  • Learning the language of thought: machine learning to infer spatiotemporal rules of cognition from mesoscopic calcium imaging data – Infer patterns in brain activity by applying natural language processing to large-scale calcium imaging datasets from awake behaving mice. A background in computer science, applied math, computational biology, machine learning, and experience working with large datasets is preferred. A strong interest (but not necessarily experience) in neuroscience is required.
  • Toward the neural bases of cooperative social interactions through a unique primate model - Unravel the prefrontal mechanisms underlying cooperation using a unique freely behaving marmoset model. Candidates should have experience in at least two of the following areas: non-human primate behavior, electrophysiology, or computational analysis.
  • The functional genomics of human cognition: from molecular and cellular processes though large-scale brain networks - Explore how genetic variation results in cognitive and behavioral differences by developing processes to link data across genetics, genomics, neuroimaging, and behavioral domains. Applicants should have demonstrated expertise in clinical, cognitive, translational, or network neuroscience, computational biology, or genetics.
  • Open Area – If you are an early-career researcher interested in foundational studies of the mind, but do not fit the priority areas above, we still welcome your application. We are particularly interested in candidates from underrepresented backgrounds with expertise in molecular and cellular neuroscience, systems and cognitive neuroscience, computational neuroscience, psychology, data science, artificial intelligence, biomedical engineering, brain-machine interfaces, and neuroethology. Applications in this track will be considered depending on mentor and funding availability.
Postdoctoral position in Inflammatory Skin Disease (Damsky lab)
Posting Date: June 18, 2021

The Damsky lab in the Department of Dermatology is seeking a postdoctoral associate. Broadly, our group studies the immunology of inflammatory skin diseases and novel treatment approaches. More specifically, our interests include:

  • Understanding basic mechanisms of inflammation in the skin
  • Evaluating novel therapies in clinical trials with translational immunologic components that teach us how a targeted intervention alters the underlying immune response
  • Current disease areas include atopic dermatitis, psoriasis, sarcoidosis, alopecia areata, other inflammatory alopecias, granuloma annulare, and others.
  • We also have active projects to evaluate novel molecular diagnostics to inform personalized disease selection in these areas
  • We are also developing new murine models of skin inflammation

Depending on the applicant’s specific interests there would be an opportunity to take a leading role in multiple areas.

Qualifications

  • PhD in relevant fields such as immunobiology, cellular biology, or molecular biology
  • Experience in cell culture, flow cytometry, and other cellular methods
  • Experience with basic molecular techniques, experience with RNAseq, scRNAseq, ATAC-seq a plus but not required
  • Experience with immunofluorescence staining of tissue and fluorescence microscopy a plus but not required
  • Experience with data analysis in R a big plus, if not, a willingness to learn
  • Experience working with mice a plus but not required

Interested candidates should email a CV to:

william.damsky@yale.edu

We are looking to hire immediately and will review applications as they are received, continuing until the position is filled.

Postdoctoral position in the Department of Dermatology(Myung Lab)
Posting Date: June 18, 2021

Peggy Myung, MD, PhD, is seeking a highly motivated post-doctoral research fellow (Ph.D., M.D., or M.D./Ph.D.) for a position in her laboratory in the Department of Dermatology, Yale School of Medicine. In the Myung lab, we study how programs of hair follicle development work at the interface of regeneration and skin tumorigenesis (Developmental Cell, 2019; Cell, 2016). In particular, our lab aims to dissect the molecular and cellular mechanisms that govern embryonic hair follicle development to gain insight into how these same mechanisms are reutilized during adult hair follicle regeneration and or dysregulated in basal cell carcinoma, the most common human skin cancer. As a post-doctoral fellow in our lab, you will have the opportunity to work within a team to perform basic science research that explores the cellular and molecular dynamics that controls these processes, using novel in vivo and genomic approaches. The projects employ a broad range of techniques, including mouse genetics, multi-photon live imaging, quantitative RNA fluorescent in situ hybridization, and single-cell RNA/ATAC sequencing.  Prior research experience using these techniques is a plus but not required. The candidate will also have opportunities to present his/her data at weekly lab meetings and at intramural and national/international conferences. The overall goal is to construct and perform scientific experiments that can be shared with the scientific community at large through peer-reviewed publications and speaking opportunities. In addition, the candidate will be given career development opportunities (e.g. grant-writing and public speaking skills) that are individually tailored to his/her long-term career goals. The ultimate goal is to create an experience that is rewarding and engaging for everyone in the lab and that fosters scientific and professional growth!

The candidate will be expected to perform the following:

  1. Assist with mouse colony management, husbandry and genotyping
  2. RNA in situ hybridization and immunohistochemical stains of mouse or human tissue followed by visualization using various microscopy techniques including multiphoton microscopy, confocal microscopy, and basic immunofluorescence/brightfield microscopy
  3. Basic molecular biology techniques such as quantitative PCR, subcloning, and preparation of RNA for bulk and single-cell RNA sequencing
  4. Preparation of single-cell suspensions from mouse skin for flow cytometry and FACS sorting
  5. Basic tissue culture techniques using primary skin cells and cell lines
  6. Embryonic and adult skin dissections
  7. Intraperitoneal and gavage administration of soluble compounds (e.g. tamoxifen) to mice
  8. Use basic software/statistical tools to analyze genomic data, including R packages for single-cell RNA sequence analysis
  9. Assist with data analysis, interpretation, and generation of figure quality data for publication and/or presentations
  10. Attend intra-mural and extra-mural conferences where he/she can present research data and build professional relationships
  11. Review and present relevant literature at journal clubs or lab meetings
  12. Attend weekly dermatology and/or pathology research in progress conferences as well as weekly lab meetings
  13. Attend one-on-one meetings with the PI to review scientific data/progress and goals and to provide reciprocal constructive feedback
  14. Prepare manuscripts of his/her primary research for publication
  15. Assist with lab organization

Interested candidates should email a cover letter that briefly describes their personal and career goals as well as their research/scientific background, their CV, and at least 3 letters of reference to peggy.myung@yale.edu

Postdoctoral position in the Center of Molecular and Cellular Oncology (Müschen Lab)
Posting Date: June 18, 2021

Our group is interested in comparative analyses of normal lymphocyte development and malignant transformation towards leukemia. We cover research areas with relevance to Immunology, Hematology and Cancer Biology. Our research involves experiments with primary human leukemia cells, normal lymphocyte development in humanized mice, leukemia and stem cell transplantation models, mouse genetics, gene editing, genetic biosensors of signal transduction, optogenetics, classical molecular and cell biology, a strong emphasis on mechanistic studies in oncogenic signal transduction. We strive to promote a culture of diversity and inclusivity for all its members, focusing on career development and innovative approaches to science.

Qualifications: PhD in cell or molecular biology, enthusiasm for science, willingness to think beyond established concepts and to try and learn new experimental and analytical tools. The lab takes a team science approach, being collaborative is important as well.

Your application should include in one single PDF:

CV, brief motivation statement, coordinates of three scientific mentors (references)

Methods/Techniques: Flow cytometry, mass spectrometry/quantitative phosphoprofiling, genetic biosensors of signal transduction, optogenetics, mouse genetics, bone marrow transplantation assays, retroviral gene delivery, whole exome sequencing and RNA-seq-analysis of clonal evolution of leukemia, pre-clinical drug testing in xenotransplantation models.

Recent work of the laboratory: To prevent the production of harmful autoantibodies and autoimmune disease, autoreactive B-cells and pre-malignant clones are eliminated by a process termed negative selection. Despite strict and rigorous negative selection, B-cells frequently give rise to autoimmune diseases and B-cell malignancies such as leukemia and lymphoma. Since humans can live without B-cells for extended periods of time, the Müschen laboratory systematically investigated lineage-specific vulnerabilities that are common in B-cell leukemia/lymphoma but not any other cell type. Contrary to the established dogma, these mechanisms are not only active in preventing autoimmune disease but also represent a novel class of therapeutic oncogenic targets in malignant B-cell tumors. Over the past five years, the Müschen Laboratory established innovative conceptual frameworks for the understanding of B-cell signaling mechanisms and negative selection, some of which are summarized below:

·      We discovered regulation of energy-abundance as the central determinant of negative B-cell selection: Hyperactivation of kinases downstream of an autoreactive B-cell receptor induces ATP-depletion and energy stress (Chen Nature 2015, Shojaee Nature Med 2016, Chan Nature 2017; Pan PNAS 2020).

·      Studying changes of energy-metabolism during B-cell transformation, we discovered that glucose carbon-flux was diverted in a way that left transformed B-cells uniquely vulnerable to inhibition of PP2A, an enzyme that coordinates glycolytic flux with antioxidant protection (Xiao Cell 2018).

·      We discovered that changes in cell-size are orchestrated by BCL6 and MYC. Opposed by MYC, BCL6 decreases cell-size by transcriptionally repressing glucose-uptake in favor of autophagy (Duy Nature 2012; Geng Cancer Cell 2015; Hurtz Genes & Dev 2019).

·      Tracking mechanisms of leukemia-initiation in 1,100 patients, we discovered pathway convergence as a novel therapeutic vulnerability in B-ALL. Only mutations that converged on one central pathway promoted leukemia progression. Genetic reactivation of divergent (suppressed) pathways engaged conflicting biochemical and transcriptional programs and subverted leukemia development. Pharmacological pathway reactivation to create a diverse signaling environment represents a novel strategy to prevent B-ALL relapse and drug-resistance (Chan Nature 2020).

·      Studying biophysical mechanisms of B-cell activation, we discovered that the short endosomal protein IFITM3 acts as a central scaffold for lipid-raft assembly and surface-expression of rafts-associated receptors. Membrane-recruitment of IFITM3 was essential for the initiation of PI3K-signaling, antibody affinity maturation and oncogenic B-cell transformation (Lee Nature 2020).

https://medicine.yale.edu/lab/muschen/

http://www.hhmi.org/scientists/markus-muschen

Postdoctoral position in Cardiovascular Research (Mani Lab)
Posting Date: June 17, 2021

A NIH funded postdoctoral position is immediately available in the laboratory of Dr. Arya Mani at the Cardiovascular Research Center at Yale University. The exciting project involves in vivo and in vitro molecular- and cellular-based studies to examine the role of Cela2a, a disease gene identified in the lab for atherosclerosis, diabetes and hyperlipidemia (Nature Genetics 2019) in glucose and lipid homeostasis in a mouse model of the disease.

Basic knowledge of molecular biology, cloning, expression analyses in cultured mammalian cells, protein purification, analysis of protein-protein interaction, FACS analysis, small animal handling is necessary. The applicants are closely mentored with the expectation that they work at the bench independently, interpret data, and contribute to the troubleshooting of their experiments. Excellent communication and interpersonal skills are a requirement for this position. Salary based on research experience.

Please submit a single PDF file containing a brief cover letter, CV, research experience and publications and information for 3 references to arya.mani@yale.edu

Postdoctoral position in cancer biology and therapy (Glazer lab)
Posting Date: June 17, 2021

A postdoctoral position is available immediately to study a novel tumor-targeting antibody for cancer therapy. Research in the lab is focused on developing novel approaches to cancer therapy by exploiting synthetic lethal vulnerabilities and leveraging tumor targeting strategies and fundamental mechanistic studies of cancer biology. Recent publications include Sulkowski Nature 2020 (PMID: 32494005) and Kaplan Science Translational Medicine 2019 (PMID: 31092693).

We offer a dynamic and stimulating work environment for conducting cutting-edge research and for facilitating career development. Interested candidates should have a strong research track record. While prior experience in cancer biology, molecular biology, and mouse tumor models is advantageous, we welcome researchers from all biomedical research backgrounds.

Qualified candidates should send their CV and contact information for at least two references to Peter Glazer, Departments of Therapeutic Radiology and Genetics, Yale School of Medicine at: peter.glazer@yale.edu

 

 

Postdoctoral position in nuclear phase separation and protein homeostasis (Schlieker Lab)
Posting Date: June 16, 2021

The Schlieker laboratory (https://medicine.yale.edu/lab/schlieker/) is seeking highly motivated researchers to join our collaborative and interdisciplinary team at Yale. Help us to characterize the role of nuclear envelope dynamics and nuclear protein homeostasis in relation to human disease. We also want to build the next generation of global scientific leaders, offering our scientists the mentoring, resources, and creative environment to launch successful careers.

We apply a broad range of interdisciplinary approaches including CRISPR-based genome wide screens, advanced life cell imaging, biochemical reconstitution and structural approaches. With these techniques, we investigate functional genetic networks operating within the nuclear envelope, monitor membrane dynamics both in vivo and in vitro, and mechanistically dissect molecular machines that sculp and remodel nuclear membranes. Ultimately, we want to understand how defects in these processes are tied to human pathology, informing corrective therapy.

Projects are available in these areas: (i) identifying the molecular function of Torsins (essential AAA+ ATPases) in the context of nuclear pore complex assembly (https://doi.org/10.1083/jcb.201910185); (ii) analyzing the function of chaperones in modulating phase separation and protein quality control in the nucleus. (iii) functional and molecular analysis of NOMO, a novel membrane-shaping protein (https://doi.org/10.1101/2021.01.28.428001).

Research environment: Being affiliated with two departments (Department of Molecular Biophysics and Biochemistry and Department of Cell Biology), we embrace collaborative approaches and provide a diverse and nurturing training environment. As a member of the Yale Nucleus Club, we hold regular joint lab meetings labs across three departments, offering exciting opportunities for intellectual exchange, collaborations and skill development in a vibrant scientific community. Postdocs will have access to an impressive variety of state-of-the-art core facilities as well as outstanding educational resources through the Yale Center for Teaching and Learning (https://poorvucenter.yale.edu/Postdocs).

Qualified candidates should have a PhD in biochemistry, cell biology or molecular biology and have strong communication and team skills.

If interested, please contact christian.schlieker@yale.edu with a copy of your resume.

Postdoctoral position in the Section of Pulmonary, Critical Care and Sleep Medicine (Llor Lab)
Posting Date: June 11, 2021

Yale School of Medicine, Section of Digestive Diseases is looking to hire a highly motivated Postdoctoral Associate to drive innovative translational research forward in the field of colorectal cancer. The post-doctoral associate will work under the supervision of Dr. Xavier Llor and Dr. Rosa Xicola on human oriented research projects aimed at understanding several colorectal cancer aspects including disparities, early age of onset, and hereditary forms. The projects encompass a range of aspects that include organoid harvesting and growth, molecular biology, and large data set curation and analysis. The individual will also manage the high-risk registry database. The post-doctoral associate should be able to work independently as well as in a team of translational researchers in the lab and along with other, postdocs, clinical staff, fellows and students. The major experimental tools that will be used include: tissue harvesting and organoid establishment, cell line growth, next-generation sequencing, and data set management and analysis.

Job Qualification:

1. A recent graduate or about to graduate with an MD, MD-PhD, or a PhD in the field of biology or similarly related fields.

2. Experience with translational work is preferred but not necessary.

3. Knowledge of major molecular biology techniques

3. Candidate should be willing to write independent funding applications after first few years of their post-doctoral position with the goal for a career as independent investigator.

The individual will be expected to make a significant contribution to the educational and research missions of the section. There will be opportunities to work on projects autonomously while working collaboratively with faculty, staff, post docs, and students. Supervision of other research personnel and other related duties will be expected. It is an excellent opportunity to learn about biomarker work in the context of clinical medicine and interventional trials.

Review of applications will begin immediately and will continue until the position is filled.  To apply, please submit a cover letter in the body of an email and CV/references as attachments to stacy.giangrande@yale.edu

Postdoctoral position in Chemical Biology Tools to Target Melanoma
Posting Date: June 11, 2021

A postdoctoral position is available immediately to apply the tools of chemical biology to characterize and target novel melanoma driver proteins. Techniques include peptide selection and preparation, chemoproteomics, and cell-based assays. Successful candidates will have a Ph.D. or equivalent with strong preparation in protein or peptide biochemistry, recombinant DNA technology, and cell and molecular biology. Chemical biology experience is preferred. We particularly welcome candidates from backgrounds underrepresented in science to apply.

The position is supported by funding from the Melanoma Research Alliance and the YCC Meyers Award Funds . The candidate will be part of a vibrant collaboration between the research groups of Dr. Ruth Halaban, Yale University Department of Dermatology, and Dr. Sarah Slavoff, Yale University Department of Chemistry. For representative recent publications, see PMID: 33357462, PMID: 33479206, PMID: 31040916, and bioRxiv preprint doi: https://doi.org/10.1101/2021.04.20.440286.

Interested candidates are encouraged to send a CV, description of research interests, and three letters of reference to:

Sarah Slavoff, Ph.D.

Department of Chemistry
Institute of Biomolecular Design and Discovery

Yale University

West Haven, CT 06511

Email: sarah.slavoff@yale.edu

Yale-Boehringer Ingelheim Biomedical Data Science Postdoctoral Fellowship Program 2021-2024
Posting Date: June 4,2021

Yale University and Boehringer Ingelheim are seeking applications for Postdoctoral Researchers for a newly launched Biomedical Data Science Fellowship, which is a three-year full-time program. Applicants with strong biomedical data science background and research experience are invited to submit research proposals for consideration. If approved for a fellowship, they will be jointly mentored throughout the research process by Yale’s faculty and scientists from Boehringer Ingelheim. Fellows will not only have access to Yale’s robust computational resources, biomedical data repositories and faculty expertise, but also benefit from access to Boehringer Ingelheim’s corporate labs, scientists and executives. In addition to receiving research funding and mentorship, program fellows will be invited to participate in campus and corporate visits, networking events, and annual symposia.

A joint selection committee comprising representatives of Yale and Boehringer Ingelheim will set annual data-driven research themes for the program. These themes may include such topics as genomic analysis, biomarkers, data-driven therapeutic research, medical image informatics, precision medicine, and translational medicine. The selection committee will consider proposed research projects’ alignment with prioritized themes in judging submissions and post-doctoral applicants.

The ideal candidate will have earned a PhD degree in the area of, computational biology, bioinformatics, data science, or relevant scientific disciplines, as well as excellent computing skills.

They will have demonstrated analytical and communication skills, including the ability to effectively describe scientific material to both specialized and lay audiences, and strong CVs, preferably having published in high-impact journals and presented at international meetings.

Applicants should submit current CV, short summary of past accomplishments, project proposal that includes a detailed research plan, summary of how the submitted project proposal aligns with the Theme, and a statement of how the Program aligns with your educational and career goals. All information from the applicant should be submitted electronically through https://medicine.yale.edu/cbds/bdsfellowship/application/

The program will be based at the Center for Biomedical Data Science (CBDS) in New Haven, Connecticut. The center is an essential part of a growing data science hub at Yale University, which has identified integrated data science as one of its primary investment areas over the next decade. CBDS is located within Yale School of Medicine and currently supports faculty members and researchers representing such disciplines as bioinformatics, modeling, statistics, computer science, artificial intelligence, mathematics, biology, precision medicine, and public health.

Compensation is competitive and includes health insurance and other benefits afforded to postdoctoral associates at Yale.

Submission deadline: June 21, 2021 12:00am (ET) Review of applications will begin immediately.

Notification to applicants: July 19, 2021

Program start date: September 1, 2021

For more information see https://medicine.yale.edu/cbds/bdsfellowship/            

For questions concerning this search, please contact cbds@yale.edu

Postdoctoral position in Machine Leaning for Brain Image Analysis (Payabvash Lab)
Posting Date: June 4, 2021

The Department of Radiology and Biomedical Imaging at Yale University is seeking highly motivated postdoctoral associate to join our team at Payabvash Lab. The research focus is on application of deep-learning for automated assessment of brain CT and MRI scans in patients with stroke and brain injury. Our goal is to devise novel tools for diagnosis, outcome prediction, and risk-stratification of patients with cerebrovascular diseases, based on wealth of information extracted from medical images and clinical records.

Successful applicants will have the opportunity to work in close collaboration with Department of Biomedical Engineering, and Department of Neurology at Yale. We are working on a large cohort of multi-institutional multi-national datasets to address some of the most pressing needs in patients who are susceptible to brain injury. Postdocs are expected to develop and deploy deep neural networks for medical image analysis, utilizing the available datasets. The postdocs will also oversee and lead graduate students and RAs working in the lab.

Preferred qualifications include:

  • PhD in computer science, electrical engineering, or biomedical engineering
  • Experience with application of CNN for image classification and segmentation – preferably medical images
  • Advanced programming experience and analytical skills
  • A record of publication and/or conference presentations

Qualified candidates should submit a cover letter describing previous programming experience, CV, and three references to: The Department of Radiology and Biomedical Imaging at Yale University is seeking highly motivated postdoctoral associate to join our team at Payabvash Lab. The research focus is on application of deep-learning for automated assessment of brain CT and MRI scans in patients with stroke and brain injury. Our goal is to devise novel tools for diagnosis, outcome prediction, and risk-stratification of patients with cerebrovascular diseases, based on wealth of information extracted from medical images and clinical records.

Successful applicants will have the opportunity to work in close collaboration with Department of Biomedical Engineering, and Department of Neurology at Yale. We are working on a large cohort of multi-institutional multi-national datasets to address some of the most pressing needs in patients who are susceptible to brain injury. Postdocs are expected to develop and deploy deep neural networks for medical image analysis, utilizing the available datasets. The postdocs will also oversee and lead graduate students and RAs working in the lab.

Preferred qualifications include:

  • PhD in computer science, electrical engineering, or biomedical engineering
  • Experience with application of CNN for image classification and segmentation – preferably medical images
  • Advanced programming experience and analytical skills
  • A record of publication and/or conference presentations

Qualified candidates should submit a cover letter describing previous programming experience, CV, and three references to: Payabvash_lab@yale.edu

Postdoctoral position, Bereavement Project, Child Study Center
Posting Date: May 31, 2021

The Yale Child Study Center Bereavement Project is seeking a Postdoctoral Associate to support a grant funded program which provides training and resources for healthcare professionals on topics related to child and family bereavement. The postdoctoral associate’s primary responsibilities will include (1) adapting training materials and developing curricula for various healthcare audiences on topics including (but not limited to) grief theory, child grief, parental grief, perinatal grief, traumatic grief, and how this impacts healthcare professionals, (2) delivering virtual and in-person trainings to nursing students, medical students, residents, fellows, and faculty (3) tracking and evaluating trainings delivered, (4) researching national climate of grief training in medical settings and applying these findings to further adaptations of the curriculum. Under the leadership of Dr. Amanda Lowell (project director) and Dr. Linda Mayes (PI and director of the Yale Child Study Center), the postdoctoral associate will also have a unique opportunity to select and engage in additional research and/or clinical opportunities of interest.

Qualified candidates are those who have recently completed a PhD in psychology, social work, psychiatric nursing, or related field. Competitive applicants will have demonstrated experience in program development, particularly in university health systems. Preference will be given to candidates with prior experience providing trainings, and those with interest in pediatrics and/or grief. Applicants must have strong interpersonal and public speaking skill, as well as the ability to work both independently and collaboratively. Applicants must be citizens or permanent residents of the United States. Applicants need not be licensed in a clinical discipline, as some opportunity for supervised clinical experience will be available if desired.

The position may start remotely in accordance with Yale University guidance around COVID-19 until the university resumes regular on campus operations, which is planned for August 1, 2021 and as determined by the business needs of the department.Review of applications will begin immediately and continue until the position is filled.

In accordance with university requirements for a safe return to in-person university operations, all faculty, staff, and postdoctoral and postgraduate trainees will be required to be fully vaccinated against COVID-19 by August 1. For additional information, please visit  https://your.yale.edu/work-yale/workplace-guidance/workplace-guidance-faqs

To apply, please send a single PDF documenting the following to amanda.lowell@yale.edu

1. Cover letter

2. Curriculum vitae

3. Names and contact information of three academic or clinical references familiar with the applicant’s skills and experience (reference letters are not needed at this time)

Postdoctoral position in Cardiology (Sinusas lab)
Posting Date: May 25, 2021

Work will be under the general direction of Drs. Sinusas and Thorn and will include management of research studies and associated activities in the Yale Translational Research Imaging Center (Y-TRIC). They will actively participate in research design, implementation, and daily operation of the lab related to selected research projects primarily funded by NIH grants.

Essential Duties:

·       Actively participate in research planning and scheduling.

·       Perform literature searches to optimize study protocol and experiments to meet study objectives and aims.

·       Recommend the design and implementation of multifaceted independent research projects related to currently funded projects of Dr. Sinusas.

·       Carry out independent research projects under the guidance of Drs. Sinusas and Thorn with technical support of laboratory staff.

·       Working independently under the general supervision of the Principal Investigator, perform small and large animal experiments that employ novel multimodality imaging techniques including, single photon emission computed tomography (SPECT), computed tomography (CT), echocardiography, x-ray fluoroscopy.

·       Collect, organize, and analyze data for presentation and publication.

·       Prepare reports, tables, and figures and accurately present compiled findings to PI for use in manuscripts and grant applications.

·       Presenting results at local and national meetings.

·       Supervise and train other post-doctoral fellows on techniques, use of equipment, and new experimental techniques.

·       Maintain safety records to comply with Yale policies and procedures regarding use of radiation and biohazards.

·       Prepare documents related to IACUC and IRB submission.

Experience and Training:

Doctoral degree in medicine, veterinary medicine or PhD in biological sciences or engineering.

Skills and Abilities:

·       Preference for experience in imaging and/or image processing.

·       Preference for experience with research on large animals and animal handling (particularly swine).

·       Preference for some surgical experience and post-operative care.

·       Preference for knowledge and or exposure in cardiovascular and/or pulmonary medicine and research.

·       Comfortable with the use of radiotracer and x-ray generating equipment.

Send a CV to Dr. Sinusas at albert.sinusas@yale.edu.