Yale Postdoctoral Positions

Yale University’s Nondiscrimination/Title IX Statements

Thank you for investigating postdoctoral opportunities at Yale.  Many faculty do not advertise open positions in their research groups, and you are encouraged to contact them directly to inquire about the possibility of training with them.  Other faculty advertise open positions in scholarly journals in their fields.  Finally, some post job openings on our website, and these positions are listed below.  Please click the links below to read more about each position and to find contact information for applying for the job.

Once you find a postdoctoral position your Yale department will contact you to begin the formal hiring process and to assist you in applying for an immigration visa to enter the United States if you require one.  Information about the visa process may be found at the Yale Office of International Students and Scholars website.

Postdoctoral position in molecular and circuit mechanisms in the Department of Genetics ( Jiang Lab)
Posting Date: July 1, 2020

The Jiang laboratory is looking for highly motivated candidates with PhD or MD/PhD degree from molecular genetics, molecular biology, and neuroscience for a Postdoctoral Associate appointment.  The successful candidate will work on NIH supported projects to study the molecular and circuit mechanisms underlying autism using mouse models including Shank3, Shank2, and Angelman, and new autism models. Experience and skills in molecular biology, optogenetics and chemo-genetics, ex and in vivo recording, mouse behaviors, and mouse models are preferred.  Anticipated start date will be after September 1, 2020.

Please respond with CV, a short description of relevant expertise, and the names of three references by email to yong-hui.jiang@yale.edu.

Postdoctoral position in molecular genetics and neuro-epigenetic mechanisms in the Department of Genetics (Jiang Lab)
Posting Date: July 1, 2020

The Jiang laboratory is looking for highly motivated candidates with PhD or MD/PhD degree from molecular genetics, molecular biology, and neuroscience for a Postdoctoral Associate appointment.  The successful candidate will work on NIH supported projects to study molecular genetics and neuro-epigenetic mechanisms and develop new treatments for Prader-Will and Angelman syndrome. Dissect the role of epigenetics in brain function and neurodevelopmental disorders.  Experience and skills in molecular genetics and epigenetics, genomics, CRISPR/Cas9, IPSC and brain organoids and mouse models are preferred.  Anticipated start date will be after September 1, 2020.

Please respond with CV, a short description of relevant expertise, and the names/emails of three references by email to yong-hui.jiang@yale.edu.

'Postdoctoral position in Vascular Biology investigating the mechanisms that control arterial disorders
Posting Date: June 30, 2020

Postdoctoral positions are available in the Laboratory of Dr. Raul J Guzman, Chief, Division of Vascular and Endovascular Surgery at Yale University School of Medicine.

The research program focuses on investigating the mechanisms that control arterial disorders including calcification and restenosis. The laboratory uses multiple approaches including gene knockdown, overexpression, and deficiency in cell culture, ex vivo organ culture, small animal models, and transgenic mice. Its goal is to identify novel mechanisms that control pathologic arterial responses and to develop therapeutic agents to prevent them.

Qualified applicants are those who have earned a Ph.D. or equivalent degree with a strong background in vascular biology or related fields. The candidates should have prior experience with cell and molecular biology and small animal techniques. Ideal candidates will have the ability to independently design, execute and troubleshoot experiments. They will have the ability to collect, analyze and interpret data in preparation for manuscript publication. They will also possess the ability to communicate in English both verbally and in writing to present experimental findings at internal meetings and scientific conferences.

To apply for this position please submit your CV, a cover letter, and contact details of three references to yujun.cai@yale.edu

Postdoctoral Position in MDS and Leukemia in the Yale Comprehensive Cancer Center
Posting Date: June 29, 2020

A postdoctoral position is available in Dr. Stephanie Halene’s laboratory at Yale University School of Medicine, to study cancer mutations and aberration in splicing (Liang et al., Leukemia, 2018) and RNA modifications (Gao et al., Immunity  2020) in MDS and Leukemia. The Halene Lab is also studying the effect of COVID 19 on hematologic malignancies. Located in the Yale Comprehensive Cancer Center, the Halene laboratory studies RNA splicing, RNA modifications, and genomics in hematopoietic stem cell biology and in MDS and Leukemia.

We use state of the art tools and techniques, including RNA immunoprecipitation coupled with high-throughput sequencing (eCLIP), single cell sequencing, m6A CLIP,  Riboseq, RNAseq, targeted exome seq, as well as biochemistry and functional genomics in cell lines, primary mouse models, and primary patient samples and state of the art bioinformatic analyses. In collaboration with the laboratory of Dr. Richard Flavell we have developed a unique, highly efficient xenotransplantation model for the study of human hematopoiesis, MDS, and leukemia, presenting a powerful tool to study mechanism and therapeutic approaches in vivo (Song et al., Nat Comm, 2019).

Candidates with strong background in RNA biology, hematopoiesis/leukemia, genomics,  mouse models, and/or molecular biology are particularly encouraged to apply. Strong bioinformatic skills are a plus. Applicants with a Ph.D. should submit curriculum vitae and names of three references to Dr. Stephanie Halene (halene.lab.yale@gmail.com).  Please enter “Postdoc Position” in subject line of e-mail.

Postdoctoral position in the Department of Psychiatry Division of Substance Abuse
Posting Date: June 24, 2020

The Department of Psychiatry at Yale School of Medicine invites applications for two postdoctoral associate positions focused on research in the areas of tobacco use prevention, cessation, and regulation. We have three available positions with start dates ranging from now until the positions are filled.

The postdoctoral associates could participate in projects focused on the 1) development and evaluation of e-cigarette cessation interventions in adolescent populations in collaboration with the Tobacco Research in Youth (TRY) Group, and 2) the conduct of tobacco regulatory research in adolescent and adult populations within the Yale Tobacco Center of Regulatory Science (TCORS). Within the TCORS, postdoctoral associates will have access to training on tobacco regulatory science and the opportunity to participate in a programmatic line of research aimed at investigating how flavors, sweeteners, and other constituents, as well as social media content, impact use behaviors and the appeal and addictive potential, of e-cigarettes and other tobacco products.

Competitive candidates should have: 1) a PhD in clinical, developmental, counseling, or health psychology, or a doctoral degree in public health, family studies, social work, or social welfare; 2) a strong research background; 3) interest in pursuing an academic career; 4) interest and/or background in tobacco regulatory science or tobacco prevention and cessation among youth and young adults. Strong data analytical skills would be appreciated but not required.

All postdoctoral associates will participate in core seminars on research and data analytic methods, grant development, and professional development as well as in seminars and colloquia that cover related topics, such as the ethical conduct of research and current topics in substance abuse prevention and tobacco regulatory science. Post-doctoral associates will have an opportunity to conduct independent research under the mentorship of Drs. Suchitra Krishnan-Sarin and Grace Kong.

To apply: Applicants should email a CV, a statement of interests that outlines their qualifications, research interests, and future goals, and three letters of recommendation to Dr. Grace Kong: Grace.Kong@yale.edu.

Postdoctoral position in translational research in multiple sclerosis (Pitt Laboratory)
Posting Date: June 11, 2020

The Pitt laboratory is looking for a talented senior postdoctoral fellow with background in cell biology to join our team. We conduct translational research in multiple sclerosis (MS) with the goal of understanding the mechanisms that underlie MS progression and neurodegeneration.

Our laboratory in the Department of Neurology, Yale School of Medicine, is embedded in a highly collaborative, translational neuroimmunology program that includes T cell biology, genetics and computational biology. 

The candidate will participate in our larger effort to examine how genetic risk variants dysregulate glial cell function in multiple sclerosis and Alzheimer’s disease (Ponath et al. Nature Comm. 2018), and to identify cellular subpopulations and their interactome in chronic and remyelinating MS lesions (Park et al. Acta Neuropath Comm. 2019).

Our laboratory uses cutting-edge technologies such as generation of human iPSC-derived astrocytes and microglia, highly multiplexed histological imaging (staining of individual section with 40+ antibodies), advanced computational tools for spatial analysis, as well as purification of astrocyte and oligodendrocyte nuclei from MS, Alzheimer and Parkinson’s tissue for transcriptomic and genomic profiling with sNuc-Seq and ATAC-Seq.

The candidate should have a broad neurobiology background and experience with cell-based assays in primary cultures. Expertise in generating and differentiating of iPSCs into CNS cells is desirable. Please respond with CV, a short description of relevant expertise, representative publications and the names of three references by email to david.pitt@yale.edu. The successful candidate will join the Department of Neurology for a minimum of 2 years.

Postdoctoral position in the Department of Neurology (Pitt Laboratory)
Posting Date: June 11, 2020

The Pitt laboratory is looking for a motivated junior postdoctoral fellow with background in cell biology to join our team. We conduct translational research in multiple sclerosis (MS) with the goal of understanding the mechanisms that underlie MS progression and neurodegeneration.

Our laboratory in the Department of Neurology, Yale School of Medicine, is embedded in a highly collaborative, translational neuroimmunology program that includes T cell biology, genetics and computational biology. 

The candidate will drive the development of astrocyte-derived exosomes as biomarkers for MS progression and other neurodegenerative conditions. Our laboratory uses cutting-edge technologies such as generation of human iPSC-derived astrocytes and microglia, highly multiplexed histological imaging (staining of individual section with 40+ antibodies), advanced computational tools for spatial analysis, as well as purification of astrocyte and oligodendrocyte nuclei from MS, Alzheimer and Parkinson’s tissue for transcriptomic and genomic profiling with sNuc-Seq and ATAC-Seq.

The candidate should have a broad neurobiology background and experience with cell-based assays in primary cultures. Please respond with CV, a short description of relevant expertise, representative publications and the names of three references by email to david.pitt@yale.edu. The successful candidate will join the Department of Neurology for a minimum of 2 years.

Postdoctoral position to study brain and leptomeningeal metastasis in the Department of Pathology (Nguyen Lab)
Posting Date: June 1, 2020

A fully funded post-doctoral position is available to study the molecular mechanisms of metastasis in the central nervous system. Applicants will have the opportunity to develop various aspects of their career, working in the departments of Pathology, Medicine, and Cancer Center. The applicant will also be part of a multi-disciplinary team working in collaboration with the Yale SPORE in lung cancer, Yale Brain Metastasis program, and pharmaceutical companies. More information can be found at http://medicine.yale.edu/lab/nguyen/

Applicants should recently hold or be nearly completing an MD or PhD degree in the biological sciences or related field. Candidates with experience in one or more of the following areas are encouraged to apply:

-Epigenomics.
-Immunofluorescent microscopy.
-Animal models of disease.
-Neuroinflammation.

Interested applicants should direct their CV, a brief statement of research interests, and arrange for three letters of recommendation to be sent to don.nguyen@yale.edu.

Don X. Nguyen
Associate Professor

Yale University School of Medicine

Department of Pathology

Assistant Cancer Center Director for Research Development

Yale Cancer Center

Postdoctoral position in the Department of Radiology and Biomedical Imaging (Payabvash Lab)
Posting Date: May 19, 2020

The Neuroimaging and Informatics Lab in the Department of Radiology and Biomedical Imaging at Yale University is seeking highly motivated postdoctoral fellows to join our team. The research focus is on application of deep-learning for automated assessment of brain CT and MRI scans in patients with stroke and brain injury. Our goal is to devise novel tools for diagnosis, outcome prediction, and risk-stratification of patients with cerebrovascular diseases, based on wealth of information extracted from medical images and clinical records.

Successful applicants will have the opportunity to work in close collaboration with Department of Bioengineering, and Department of Neurology at Yale. We are working on a large cohort of multi-institutional multi-national datasets to address some of the most pressing needs in patients who are susceptible to brain injury. Postdocs are expected to develop and deploy deep neural networks for medical image analysis, utilizing the available datasets. The postdocs will also oversee and lead graduate students and RAs working in the lab.

Preferred qualifications include:

  • PhD in computer science, electrical engineering, or biomedical engineering
  • Experience with application of CNN for image classification and segmentation – preferably medical images
  • Advanced programming experience and analytical skills
  • A record of publication and/or conference presentations

Qualified candidates should submit a cover letter describing previous programming experience, CV, and three references to the PI: sam.payabvash@yale.edu

Postdoctoral position in Neuroscience (Kim Lab)
Posting Date: May 12, 2020

The Kim Laboratory at Yale School of Medicine is inviting applications for a postdoctoral position to investigate mechanisms regulating visual circuit formation. We are specifically focusing on the assembly of the neural circuits mediating visual threat-triggered defensive behavior. Our research methodology combines mouse genetics, AAV-mediated neurocircuit analysis, bioinformatics, confocal microscopy and behavioral tests. The ultimate goal is to define molecular mechanisms that underlie development of previously unexplored visual circuits contributing to function and dysfunction of fear-related brain circuitry.

The ideal candidate would have a background in neuroscience, molecular genetics, cell biology or a related field. Previous experience in molecular biology and histology is required. Familiarity with mouse models, experience in in vivo surgery or behavioral testing is a plus but not a requirement.

Interested candidates should e-mail their application to in-jung.kim@yale.edu. The application should include: (1) CV with the publication list, (2) a brief description of research interests, (3) contact information for 2-3 references.

Postdoctoral position in the Department of Nephrology (Somlo Lab)
Posting Date: May 5, 2020

Yale School of Medicine is seeking a several motivated Postdoctoral Associates to join research programs in the laboratory of Stefan Somlo focused on the study of human genetics, cilia biology and signaling as it pertains to human genetic kidney, liver and intracranial aneurysm diseases—all part of the spectrum of human polycystic kidney disease. The research opportunities run the spectrum from human disease modifier gene discovery to utilization of novel mouse and fish disease models for in vivo pathway discovery and validation. The approaches are founded on interpretation of large data sets from human genome level sequence data and mouse cell type specific transcriptome sequence data coupled with model organism genetics and basic cellular and molecular biology. The goals of the program are to discovery new biology and define targets for human disease treatment.

Applicants should have a Ph.D. and/or M.D., with interest in genetics, model organisms, molecular biology, cell biology, or related fields. Interest in combining these with basic bioinformatics analyses is desirable but not necessary.

All applications materials should be submitted electronically to: Carol Brown, HR Administrator at carol.brown@yale.edu. Review of applications will begin immediately and will continue until the position is filled.

Postdoctoral position on COVID-19 (virology/immunology)-Wilen lab
Posting Date: April 20, 2020

The laboratory of Craig Wilen, MD, Ph.D, located at the Yale School of Medicine in the Departments of Laboratory Medicine and Immunobiology, is looking to recruit highly motivated and passionate postdoctoral scientists interested in virology and immunology.

The Wilen lab interested in how viruses interact with and evade the immune system.  We currently have two areas of focus: COVID-19 and norovirus.  This position would work primarily on COVID-19.  We use a variety of techniques including CRISPR screening, single-cell RNA sequencing and organoids to understand host-viral interactions and to identify therapeutic targets.

Successful candidates should have backgrounds in virology, immunology, or a related field. Individuals with a track record of publications, prior experience in a BSL-3 facility, and recent PhD graduates are strongly encouraged to apply. The Wilen Lab provides a stimulating and highly collaborative training environment.

Interested candidates should send their CV to Dr. Wilen at craig.wilen@yale.edu

Postdoctoral Associate in Psychosis and Computational Psychiatry Yale School of Medicine, Department of Psychiatry
Posting Date: March 23,2020

The Powers Laboratory at Yale is recruiting two full-time post-doctoral fellows to work on two new NIMH-funded studies in psychosis. 

The first is a multi-site study involving Yale, Northwestern University, UMBC, and UGA, evaluating the efficacy of a battery of behavioral tests for tracking symptom severity and risk of conversion among patients at Clinical High Risk for Psychosis (CHR-P).  In addition to collaborating across sites, candidates will also work with Drs. Phil Corlett, Scott Woods, and Barbara Walsh at Yale. 

The second project uses performance on a simple perceptual task and computational modeling to predict behavioral and neural responses to cholinergic manipulation.  Our goal is to use the knowledge generated to take the first steps toward a computationally-informed, personalized treatment approach to hallucinations.

Activities for both positions will include data collection, analysis of behavioral and functional imaging data using cutting-edge computational modeling, and reporting in the form of journal articles and presentations at national and international meetings.  Ideal candidates will have experience with behavioral data collection and analysis, basic working knowledge of MATLAB or other technical computing languages, expertise in sensory neuroscience, and a background in working with individuals with psychosis-spectrum illness. Duration and start date are negotiable but a minimum of a two-year commitment is required.  Timing of hire will also depend on resolution of hiring restrictions currently in place due to the COVID-19 crisis.

Salary and benefits package are highly competitive. Interested candidates should send a letter of interest, CV, and the names of three references to Al Powers, M.D., Ph.D. by email: albert.powers@yale.edu

Postdoctoral position in Metabolism
Posting Date: March 11, 2020

Daniel Vatner M.D., Ph.D. in the Yale School of Medicine Section of Endocrinology and Metabolism is looking to hire a highly motivated postdoctoral fellow to do exciting translational basic science studies, with an emphasis on in vivo physiology and molecular biology.  We investigate the physiology of the metabolic syndrome, studying numerous rodent models and human subjects with state of the art techniques.  We seek to understand the metabolic fluxes that drive excess triglyceride production in the setting of insulin resistance; additionally, in collaboration with other laboratories at the School of Medicine, we are investigating links between metabolic dysfunction and the progression of nonalcoholic fatty liver to NASH.  The postdoctoral fellow will work on projects both independently and in multi-laboratory collaborations (working alongside students, fellows, technicians, and other investigators).

Candidates for this position should be recent graduates with a PhD, MD, or equivalent degree.  Candidates must be eligible for a position on an NIH T32 training grant restricted to US citizens and permanent residents.  Expectations include those important for growing the fellow’s research career, including presenting at meetings and preparing manuscripts, and those important for a properly-functioning laboratory, including participation in mouse colony maintenance and laboratory organization.

Interested applicants should send a cover letter briefly outlining research experiences, career goals, references, and expected availability date, along with a CV to daniel.vatner@yale.edu.

Postdoctoral position in the Section of Pulmonary, Critical Care and Sleep Medicine
Posting Date: March 6, 2020

Yale School of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine (PCCSM), is looking to hire a highly motivated Postdoctoral Fellow to drive innovative research projects forward in the laboratory of Dr. Charles Dela Cruz, MD, PhD. The post-doctoral fellow will work on understanding the host-pathogen interactions at cellular and molecular levels during bacterial and viral infections in disease models of pneumonia, COPD and fibrosis. The post-doctoral fellow should be able to work independently as well as in a team of other researchers in the lab which include other postdocs, clinical fellows and students. The major experimental tools that will be used include animal models, multicolor flow cytometry, knockdown and overexpression studies and imaging techniques using bacterial and viral infection along with techniques of viral and or bacterial culture, western blotting and ELISA.

Job Qualification:

1. A recent graduate or about to graduate from PhD in the field of biology, immunology, bacteriology, virology or similarly related fields.

2. Experience with animal handling is preferred but not necessary. Knowledge about the major cellular and biochemical techniques will be plus.

3. Candidate should be willing to write independent funding applications after first few years of their post-doctoral position with the goal for a career as independent investigator.

The Postdoctoral Fellow is expected to make a significant contribution to the educational and research missions of the section. There will be opportunities to work on projects autonomously while working collaboratively with faculty, staff, post docs, and students. Supervision of other research personnel and other related duties will be expected.

Review of applications will begin immediately, and will continue until the position is filled.  To apply, please submit a cover letter in the body of an email and CV/references as attachments to charles.delacruz@yale.edu

Postdoctoral position in the Dept. of Molecular, Cellular and Developmental Biology (Breslow's Lab)
Posting Date: March 3, 2020

David Breslow’s lab, part of the Dept. of Molecular, Cellular and Developmental Biology at Yale University, is seeking a post-doctoral researcher interested in understanding the functions of the mammalian primary cilium, with a focus on defining the mechanisms that regulate cilium assembly and disassembly.

Located in the newly constructed Yale Science Building, the Breslow lab aims to understand the mammalian primary cilium – a micron-scale structure protruding from the surface of most cells in the human body. Using a combination of functional screening, microscopy and biochemistry, we are investigating the basic processes by which cilia are assembled, maintained, and disassembled. Areas of particular interest include understanding how the cilium serves as an organizing center for select signaling pathways and dissecting the complex interplay between cilium assembly/disassembly and the cell cycle. Additionally, we have a strong interest in developing and applying new functional genomic and imaging technologies. Collectively, our studies aim to provide fundamental biological insights, to shed light on the pathogenic mechanisms of cilium-based diseases, and to reveal new strategies for targeting cancers in which ciliary function is altered.

Applicants should hold (or anticipate award of) a Ph.D. in a relevant area of biological research such as cell biology, biochemistry, or genetics. A multi-year position is available from April 1, 2020.  Please send a cover letter briefly summarizing your research experience and goals, a CV, and contact information for 2-3 references to david.breslow@yale.edu

Cancer Biology Postdoctoral position in Medical Oncology
Posting Date: March 2, 2020

The Wilson laboratory in the Section of Medical Oncology and the Yale Cancer Center is seeking candidates for a postdoctoral position.  Interests in the laboratory focus on identifying and characterizing genetic vulnerabilities in cancer and molecular mechanisms of drug resistance with an emphasis on lung cancer therapeutics (https://medicine.yale.edu/bbs/people/frederick_wilson-1.profile). The lab leverages genome-scale functional genomic screening approaches (such as CRISPR and RNA interference) to identify cancer vulnerabilities and dissect resistance mechanisms in relevant cancer cell models.  The lab also applies sequencing-based approaches to identify candidate driver gene alterations from patient tumor specimens for mechanistic studies in cell model systems.  A major priority is to translate laboratory findings into therapeutic strategies for patients with lung and other cancers.
 
Applicants must have a recent PhD degree in a relevant field and at least one first author publication in a peer-reviewed journal. Applicants should have experience in molecular biology, genetics / genomics, tumor cell biology, or other related fields.  Excellent written and oral communication skills are expected.
 
Candidates should send a Curriculum Vitae, a statement of research interests and career goals and the names / contact information for three references to: frederick.wilson@yale.edu.
 

Postdoctoral Fellow position in HIV/AIDS
Posting Date: February 27, 2020

A Postdoctoral Fellow position is now open to study host genetic control of HIV, in the Department of Internal Medicine, Section of Infectious Diseases at Yale School of Medicine (New Haven, CT, USA).  A PhD or equivalent advanced degree in Biomedical, Biochemistry, Biology, Cell Biology, Microbiology, Veterinary Medicine, Animal Sciences, or related field is required.

This is a research based position and prior investigative experience in the areas of molecular biology, cell biology, immunology, and microbiology are required. The incumbent will be responsible for planning and conducting experiments, maintaining laboratory records and writing/editing manuscripts and articles, completing diagnostic tests and determining, carrying out and modifying methods, procedures and techniques, designing, fabricating, calibrating and repairing research equipment as necessary; preparing grant applications. Knowledge of mammalian cell culture, propagation of HIV, and related molecular biology methods is essential.

If interested, please contact Richard Sutton, MD-PhD; email: richard.sutton@yale.edu.

Postdoctoral position in Cancer Biology
Posting Date: February 20, 2020

The Escobar-Hoyos lab in the Department of Therapeutic Radiology and Yale Cancer Center at Yale University is seeking a highly motivated and creative post-doctoral researcher with a background in cancer biology and/or RNA biology, or related fields to join our team.

We are seeking a dynamic individual who will be responsible, as a member of a team, for designing and executing studies focused on understanding and targeting altered RNA processing mechanisms in pancreatic cancer.

As the most common form of pancreatic cancer, pancreatic ductal adenocarcinoma (PDAC) has emerged as the 3rd leading cause of cancer death in the United States, in part because this malignancy is highly resistant to chemotherapeutic  intervention.

Recently, it’s been shown that PDAC is composed of distinct molecular subtypes, based on RNA expression and patient outcome, underscoring that much remains to be understood about RNA expression, processing and regulation in this disease. Our research is focused on 1) characterizing the molecular pathways and functions controlled by aberrant RNA splicing and 2) designing RNA- targeted therapies to uncover novel therapeutic vulnerabilities in this disease.

Our group is heavily involved with RNA Sequencing of human and mouse pancreatic cancers. The candidate is expected to perform experiments exploring alterations in RNA splicing and additional steps in RNA processing, using a variety of preclinical model systems that include cell lines, xenografts, genetically engineered mouse models, and patient-derived models. A desire to develop and implement new methodologies is highly advantageous. There will be numerous opportunities for training to complement current skills, collaborate with other outstanding scientists, and to enhance grant writing skills.

The candidate will work within an integrated, multidisciplinary team composed of basic scientists, computational biologists, pathologists, medical oncologists, and radiologists, with significant resources for bioinformatics support, access to clinical specimens, and studies in human and animal tissues.

Applicants should have completed a PhD in cell biology or a related field and have a strong publication record, excellent verbal and written communication skills and strong research experience in signal transduction, transcriptional control, RNA splicing, genomics and bioinformatics, or related fields. Recent PhD graduates or current PhD candidates completing their studies are encouraged to apply.

Experience with several of the following activities are desirable: characterization of genetically engineered mouse models, work with patient-derived xenografts or organoids, and culture of primary cells. Initial salary is commensurate with experience. Applying for independent funding is not required but is strongly encouraged for the career development of the candidate.

Qualified candidates should send a curriculum vitae, a cover letter detailing research interests and career goals, and contact information for three references to Dr. Luisa Escobar-Hoyos (luisa.escobar-hoyos@yale.edu).

Postdoctoral position in the Schalper Research Lab in the Department of Pathology
Posting Date: February 18, 2020

The Schalper Research Lab in the Department of Pathology at Yale University has an opening for a postdoctoral position.  The lab is focused on understanding the immunobiology of human solid tumors using quantitative pathology, computational image analysis, in vitro cell models and molecular biology to interrogate relevant immunomodulatory pathways and identify determinants of sensitivity and resistance to treatments. Our lab has access to cutting-edge technology and has unique opportunities to develop translational research projects in human lung and colorectal cancer.  More information can be found at https://medicine.yale.edu/lab/schalper/

We are looking for a highly motivated individual interested in studying tumor-immune cell interactions focusing on dominant T-cell regulatory pathways with therapeutic potential. Interested applicants should hold a Ph.D. or MD/Ph.D. degree and a strong background in the field of immunology and/or translational oncology/pathology. The candidate should be self-motivated with a proven track record of productivity.  In addition to individual projects, the lab encourages a collaborative and positive working environment with other lab members and throughout the University and Cancer Center.

The competitive candidate should have knowledge and expertise in the following areas:

  1. T-cell biology, immune-oncology and immunomodulatory therapies
  2. Solid tumor oncology and translational pathology
  3. Advanced cancer diagnostics and immune-based anti-cancer therapeutics
  4. Computational analysis of images and large datasets

Candidates with the following qualifications will be given preference:

  1. Interest and expertise in the field of immunology/immune-oncology
  2. Productivity, quality of previous projects and independence
  3. Ability and interest to work in translational research within a multidisciplinary team

Qualified candidates who are interested in applying should e-mail an application package, including; statement of interest, CV, and contact information for three references. Please send your application package to Dr. Kurt Schalper (kurt.schalper@yale.edu) and in the subject line include your last name and reference to the job posting.  For technical assistance and questions, please e-mail Lindsey Behlman (lindsey.behlman@yale.edu).   

Postdoctoral position in the Myung Laboratory in the Department of Dermatology
Posting Date: February 18, 2020

Peggy Myung, MD, PhD, is seeking a highly motivated Postdoctoral Associate (Ph.D., M.D., or M.D./Ph.D.) in her laboratory in the Department of Dermatology, Yale School of Medicine. In the Myung lab, we study how programs of hair follicle development work at the interface of regeneration and skin tumorigenesis (Developmental Cell, 2019; Cell, 2016). In particular, our lab aims to dissect the molecular and cellular mechanisms that govern embryonic hair follicle development to gain insight into how these same mechanisms are reutilized during adult hair follicle regeneration and or dysregulated in basal cell carcinoma, the most common human skin cancer. As a post-doctoral fellow in our lab, you will have the opportunity to work within a team to perform basic science research that explores the cellular and molecular dynamics that controls these processes, using novel in vivo and genomic approaches. The projects employ a broad range of cutting-edge techniques, including mouse genetics, multi-photon live imaging, quantitative RNA fluorescent in situ hybridization, and single-cell RNA/ATAC sequencing.  Prior research experience using these techniques is a plus but not required. The candidate will also have opportunities to present his/her data at weekly lab meetings and at intramural and national/international conferences. The overall goal is to construct and perform scientific experiments that can be shared with the scientific community at large through peer-reviewed publications and speaking opportunities. In addition, the candidate will be given career development opportunities (e.g. grant-writing and public speaking skills) that are individually tailored to his/her long-term career goals. The ultimate goal is to create an experience that is rewarding and engaging for everyone in the lab and that fosters scientific and professional growth!

The Postdoctoral Associate candidate will be expected to perform the following:

  1. Assist with mouse colony management, husbandry and genotyping
  2. RNA in situ hybridization and immunohistochemical stains of mouse or human tissue followed by visualization using various microscopy techniques including multiphoton microscopy, confocal microscopy, and basic immunofluorescence/brightfield microscopy
  3. Basic molecular biology techniques such as quantitative PCR, subcloning, and preparation of RNA for bulk and single-cell RNA sequencing
  4. Preparation of single-cell suspensions from mouse skin for flow cytometry and FACS sorting
  5. Basic tissue culture techniques using primary skin cells and cell lines
  6. Embryonic and adult skin dissections
  7. Intraperitoneal and gavage administration of soluble compounds (e.g. tamoxifen) to mice
  8. Use basic software/statistical tools to analyze genomic data, including R packages for single-cell RNA sequence analysis
  9. Assist with data analysis, interpretation, and generation of figure quality data for publication and/or presentations
  10. Attend intra-mural and extra-mural conferences where he/she can present research data and build professional relationships
  11. Review and present relevant literature at journal clubs or lab meetings
  12. Attend weekly dermatology and/or pathology research in progress conferences as well as weekly lab meetings
  13. Attend one-on-one meetings with the PI to review scientific data/progress and goals and to provide reciprocal constructive feedback
  14. Prepare manuscripts of his/her primary research for publication
  15. Assist with lab organization

Interested candidates should email a cover letter that briefly describes their personal and career goals as well as their research/scientific background, their CV, and at least 3 letters of reference to peggy.myung@yale.edu

Postdoctoral Associate position in Internal Medicine- Infectious Diseases
Posting Date: February 12, 2020

The scientific focus of the laboratory is to study the intersection of immunology, infection, and cancer biology.  The lab studies the immunology of cancer incidence in the setting of chronic viral infection, including HIV, HPV and EBV.  Focus of lab will be to determine immune correlates of increased cancer incidence and biomarkers of worse prognosis in the setting of chronic viral infection like HIV.  The laboratory has clinical, translational, and basic science components and is highly collaborative with other laboratories in Pathology, Surgery, Neurology, the Cancer Center, and Immunology.  Under the direction of the PI but with expectation to exercise independent judgment, this position will have the role of planning research projects, designing experiments, training staff, ensuring all safety and research compliances are met, and managing sponsored research awards.

 

Ideal candidates would have strong background in immunology, virology, molecular biology, genetics, and/or computational biology.  Excellent oral and written communication skills are required.  Interested applicants should send a CV, cover letter describing research experiences and interest, and 3 references to Brinda.emu@yale.edu.

Postdoctoral position at the Yale Center for Environmental Law & Policy
Posting Date: February 5, 2020

The Yale Center for Environmental Law & Policy (envirocenter.yale.edu) seeks a two-year Postdoctoral Associate to serve as the project director for the Environmental Performance Index (EPI) (epi.yale.edu). For over twenty years, the EPI has been a flagship project of the Center, ranking countries on high priority environmental issues in two areas: protection of human health and ecosystem vitality. Leading the project includes mobilizing a team of partners, researchers, and experts, while taking primary responsibility for the framing, data analysis, and production of a high-quality report. In addition to the EPI, we are looking for an individual who can provide intellectual leadership and innovative approaches with other research projects related to environmental data analytics and contribute to various workstreams at the Center.

Essential Duties

  • Oversee all elements of the production of the 2018 EPI report, including data gathering, methodology development, data review and assessment, and communication of results;
  • Work closely with the EPI Team, including Yale faculty and our partners at Columbia University’s Center for International Earth Science Information Network;
  • Contact and consult data partners at other institutions, including academic research centers, think tanks, and non-governmental organizations;
  • Ensure methodological rigor and scientific accuracy of the EPI through surveying the latest advances in environmental data, developing novel metrics and indicators, refining existing methods, and interrogating data and results;
  • Manage data and research materials, including developing and enforcing systems for documentation and retention of data collection and analysis, meeting notes, correspondence, code, written drafts, and all other materials necessary for complete transparency and replication of the project;
  • Coördinate day-to-day operations and administration of the EPI, including hiring and supervising student research assistants, developing and tracking budgets, and managing contracts with vendors;
  • Develop and implement a communication strategy for disseminating the results of the 2020 EPI, including event planning for the release, preparation of the website, engagement with traditional and social media, and other opportunities for presenting the project to diverse audiences;
  • Answer inquiries from international media, government officials, academic researchers, and members of civil society;
  • Lead the writing of the 2020 EPI report, website, summary, and technical appendix;
  • Work with Professor Dan Esty, other Yale faculty, and research partners to produce academic journal articles and other publications related to the EPI results; and
  • Otherwise support the work of the Center, including contributing to fundraising efforts and writing reports and other materials for donors.

Education & Experience

  • Ph.D. in applied, quantitative social science with an environmental emphasis. Possible fields include Public Affairs, Public Policy, Environmental Studies, Sustainability, Geography, International Development, Statistics, Political Science, and Economics.
  • Statistics or Econometric expertise required, through doctoral training and research experience.
  • Broad knowledge of environmental science and policy, especially in the areas of climate change, biodiversity, and international sustainable development.

Skills & Abilities

The ideal candidate will possess

  • Excellent research, writing, interpersonal, and communication skills;
  • Experience with interdisciplinary research and collaborations;
  • Demonstrated leadership and project management experience;
  • Ability to work under pressure, meet tight deadlines, and manage multiple pressing responsibilities with minimal supervision; and
  • A high level of computational ability, including fluency or the ability to rapidly learn data management, GIS, and statistical software, especially R.

Schedule & Compensation

This is a full-time position for two years to run Summer 2020 – Summer 2022. The start date is flexible, but we cannot offer a deferral. The position requires working during normal business hours throughout the calendar year with occasional travel. Salary is competitive and includes a benefits package through Yale University.

Application Guidelines

  • Application deadline is 13 March  2020, though review of applications will continue until the position is filled.
  • Please email a cover letter and CV as a single PDF to epi@yale.edu
    • Letters may be addressed to Prof. Dan Esty, Yale Center for Environmental Law & Policy, 195 Prospect Street, New Haven, CT 06511.
    • Cover letters should address qualifications for this position rather than summaries of research and publications.
  • If invited, candidates may be asked for additional materials, including writing samples and references.