Yale Postdoctoral Positions

Postdoctoral position for a highly motivated graduate student to join the Yale Psychiatry Division of Human Genetics, a productive and collaborative research environment with a focus on the genetics of psychiatric illnesses, behavioral phenotypes, and other complex traits founded by Dr. Joel Gelernter. The successful candidate will work with Dr. Daniel Levey on projects funded by the Brain & Behavior Research Foundation and the U.S. Department of Veterans Affairs, investigating the genetics of depression and anxiety disorders and related psychiatric traits in the VA Million Veteran Program dataset (one of the world’s largest and most informative biobanks) and the Psychiatric Genomics Consortium (the largest experiment in the history of biological psychiatry). Additional opportunities will include the analysis of a growing sample in the deeply phenotyped Yale-Penn cohort with genetics, RNAseq, and epigenetic data. Collaborations with other investigators within the division will be strongly encouraged.

Applicants must have or be about to be awarded a Ph.D. and/or M.D. The ideal candidate will have a strong background in human genetics or transcriptomics, including knowledge of genome-wide methods or RNAseq, including GWAS and downstream in-silico analyses and comfort with bioinformatics. The candidate should also be able to work cooperatively with peers at Yale and with many other collaborators nationally and internationally, and bring research to publication. The start date is flexible.

Please send your application (including CV and contact information for three references) by email to Dr. Levey at daniel.levey@yale.edu<mailto:daniel.levey@yale.edu> with Postdoctoral Associate in the title.

Cameron Gettel, MD, MHS, Assistant Professor, Clinician Scientist, in the Department of Emergency Medicine is actively seeking a Postdoctoral Associate to add to his growing team. This is a new program where Dr. Gettel plans to blend academic emergency medicine, health services research, and health policy as it relates to the growing geriatric population, including persons living with dementia and their caregivers. See duties and qualifications below.

Job Duties

The initial appointment is one year and renewable for up to six years total, with preference given to those who can commit to at least two years in the position.

The position includes opportunities for professional development and interdisciplinary training, as well as the opportunity to be part of the large and vibrant community of health services researchers at Yale University, Department of Emergency Medicine.

1. Screening, enrollment, medical record data abstraction of in-ED research participants
2. Secondary data analyses of datasets including HCUP, MCBS, and NHATS/NSOC among others
3. Coordination of research efforts between sites
4. Drafting grant proposals and protocols
5. Primary and/or secondary authorship of original research manuscripts

Qualifications and Skills

• Doctoral degree (MD or PhD) with interest in mixed methods research, health services research, geriatrics
• Strong quantitative skills with data cleaning and analysis as well as manuscript drafting and publication
• Focus on team-oriented research

Application Process

Review of applications will begin immediately and will continue until the position is filled. If interested, please send CV, cover letter and references to Dr. Cameron Gettel at cameron.gettel@yale.edu and Jackie Santana at jackeline.santana@yale.edu.

The anticipated start date is September 2021. In accordance with university requirements for a safe return to in-person university operations, all faculty, staff, and postdoctoral and postgraduate trainees will be required to be fully vaccinated against COVID-19 by August 1. For additional information, please visit https://your.yale.edu/work-yale/workplace-guidance/workplace-guidance-faqs.

The Foxman lab at the Yale School of Medicine is seeking postdoctoral researchers to join our team investigating innate immunity, host-virus interactions, and post-injury tissue repair in the human respiratory tract. Our lab spans the basic to translational spectrum, using patient samples, primary human cells, and organoid models, and techniques such as transcriptomics, proteomics, and single cell RNA Seq.  Background/interest in the following areas a plus: immunology, virology, next generation sequencing, single cell analysis. For more information about our recent work on host-virus interactions in the human respiratory tract, including studies of rhinovirus, influenza, and SARS-CoV-2, see our lab website at https://medicine.yale.edu/lab/foxman/.  

Our lab is in the Yale Department of Laboratory Medicine, and is affiliated with the Yale Department of Immunobiology, affording candidates access to a large network of colleagues doing exciting research and outstanding career development opportunities such as participation in departmental retreats, research in progress talks, and career development programming.  Dr. Foxman is also deeply committed to professional development and creating a plan that enables each post-doc to reach their career goals.

Please email statement of interest, C.V., and names of three references to ellen.foxman@yale.edu.

Requirements: PhD, MD, or MD/PhD and relevant training and publication record.

We are inviting motivated Postdoctoral Scientists to join our group to study the physiology, and the molecular and genetic mechanisms involved in host-pathogen interactions in the tsetse fly-African trypanosome system. We study the role of the fly immune system and the influences of tsetse’s endosymbiotic bacteria in the parasite infection process.  We also investigate parasite mediated mechanisms that modify tsetse’s vector competence efficiency and influences the transmission success of trypanosomes to the next mammal in fly saliva. Finally, we are developing transmission blocking vaccines that target antigens present on the parasites in saliva that are deposited to the mammalian bite site.

We are looking for highly motivated scientists trained in a related field such as entomology, microbiology or immunology.  Our lab provides a collaborative environment and multi-disciplinary training for scientific and career development. Our lab has a track record of training postdoctoral researchers: our postdocts have international conference presentations and first authored original articles in high impact journals. We also have extensive international collaborations with researchers in Africa which provide a rich training environment for our researchers in global health.

The successful candidate will likely have (a) a recent (,4-years) PhD degree in entomology, microbiology or immunology or a related discipline; (b) a track record of research productivity , as evidenced by first authored original publications in high quality peer-reviewed journals; (c) experience in–omics based technologies, and parasite or insect cultures; (d) experience with BSL2 procedures; (e) independence to lead a project as well as willingness to work in a team; (f) an open mind to learn new methods from collaborators and (g) good scientific presentation and writing skills. Previous experience in immunology, parasitology and bioinformatics are preferred. Salary and benefits are according to Yale and NIH guidelines.

Interested candidates may send a CV, personal statement and contact information for three references to Serap Aksoy (serap.aksoy@yale.edu).  Interested candidates can obtain additional information on our work https://ysph.yale.edu/profile/serap_aksoy/.  Below are a few of our recent publications.

1. Aksoy E, Vigneron A, Bing X, Zhao X, O’Neill M, Wu YN, Bangs JD, et al. (2016) Mammalian African trypanosome VSG coat enhances tsetse’s vector competence. Proc Natl Acad Sci U S A 113: 6961-6966.

2. Bing X, Attardo GM, Vigneron A, Aksoy E, Scolari F, Malacrida A, Weiss BL, et al. (2017) Unravelling the relationship between the tsetse fly and its obligate symbiont Wigglesworthia: transcriptomic and metabolomic landscapes reveal highly integrated physiological networks. Proc Biol Sci 284.

3. Vigneron A, O’Neill MB, Weiss BL, Savage AF, Campbell OC, Kamhawi S, Valenzuela JG, Aksoy S. Single-cell RNA sequencing of Trypanosoma brucei from tsetse salivary glands unveils metacyclogenesis and identifies potential transmission blocking antigens. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2613-2621.

4. Michalkova V, Benoit JB, Weiss BL, Attardo GM, Aksoy S (2014) Vitamin B6 generated by obligate symbionts is critical for maintaining proline homeostasis and fecundity in tsetse flies. Appl Environ Microbiol 80: 5844-5853.

5. Weiss BL, Savage AF, Griffith BC, Wu Y, Aksoy S (2014) The Peritrophic Matrix Mediates Differential Infection Outcomes in the Tsetse Fly Gut following Challenge with Commensal, Pathogenic, and Parasitic Microbes. J Immunol 193: 773-782.

6. Vigneron A, Aksoy E, Weiss BL, Bing X, Zhao X, Awuoche EO, O’Neill MB, et al. (2018) A fine-tuned vector-parasite dialogue in tsetse’s cardia determines peritrophic matrix integrity and trypanosome transmission success. PLoS Pathog 14: e1006972.

7. Weiss BL, Wang J, Maltz MA, Wu Y, Aksoy S. Trypanosome infection establishment in the tsetse fly gut is influenced by microbiome-regulated host immune barriers. PLoS Pathog. 2013;9(4):e1003318.

Come join a community dedicated to understanding the mind and cognition through integration across disciplines, organisms, and scales.

The Wu Tsai Postdoctoral Fellowship program at Yale seeks scientists who are excited about frontiers in interdisciplinary neuroscience and who represent a diversity of identities, including those from historically underrepresented backgrounds in science.

Apply to one of four priority co-mentored projects, carefully selected for their science and inclusive and supportive training environments, or submit an application to our open track.

Fellows receive:

• Competitive stipend ($60,000), health benefits, and discretionary training funds for a maximum of three years, upon annual review
• Cohort-based professional development and community-building activities
• Access to cutting-edge facilities at the new Wu Tsai Institute

Eligibility:

• PhD degree or equivalent, awarded within past three years
• Track record of discoveries and demonstrated level of scientific independence appropriate for a beginning postdoc
• Self-identifying as being a member of a group underrepresented science. and/or demonstrated commitment to fostering diversity, equity, and inclusion.
• Interdisciplinary orientation
• International applicants welcome
• Current Yale postdocs and PhD students are not eligible to apply

Deadline for applications is August 15.

To apply and for more info see: https://bit.ly/WTIPostdocFellows

Priority areas include:

• Uncovering the molecular basis of neuroticism, a fundamental personality trait - Explore the effect neuroticism-associated DNA variants on gene expression and develop massively parallel reporter assays to test effects on neural systems. Applicants should have expertise in stem cell biology, neuroscience, massively parallel reporter assays, high-throughput CRISPR genomic manipulations, and/or statistical genetics and epigenetics, and be interested in bridging computational and experimental approaches.
• Learning the language of thought: machine learning to infer spatiotemporal rules of cognition from mesoscopic calcium imaging data – Infer patterns in brain activity by applying natural language processing to large-scale calcium imaging datasets from awake behaving mice. A background in computer science, applied math, computational biology, machine learning, and experience working with large datasets is preferred. A strong interest (but not necessarily experience) in neuroscience is required.
• Toward the neural bases of cooperative social interactions through a unique primate model - Unravel the prefrontal mechanisms underlying cooperation using a unique freely behaving marmoset model. Candidates should have experience in at least two of the following areas: non-human primate behavior, electrophysiology, or computational analysis.
• The functional genomics of human cognition: from molecular and cellular processes though large-scale brain networks - Explore how genetic variation results in cognitive and behavioral differences by developing processes to link data across genetics, genomics, neuroimaging, and behavioral domains. Applicants should have demonstrated expertise in clinical, cognitive, translational, or network neuroscience, computational biology, or genetics.
• Open Area – If you are an early-career researcher interested in foundational studies of the mind, but do not fit the priority areas above, we still welcome your application. We are particularly interested in candidates from underrepresented backgrounds with expertise in molecular and cellular neuroscience, systems and cognitive neuroscience, computational neuroscience, psychology, data science, artificial intelligence, biomedical engineering, brain-machine interfaces, and neuroethology. Applications in this track will be considered depending on mentor and funding availability.

Peggy Myung, MD, PhD, is seeking a highly motivated post-doctoral research fellow (Ph.D., M.D., or M.D./Ph.D.) for a position in her laboratory in the Department of Dermatology, Yale School of Medicine. In the Myung lab, we study how programs of hair follicle development work at the interface of regeneration and skin tumorigenesis (Developmental Cell, 2019; Cell, 2016). In particular, our lab aims to dissect the molecular and cellular mechanisms that govern embryonic hair follicle development to gain insight into how these same mechanisms are reutilized during adult hair follicle regeneration and or dysregulated in basal cell carcinoma, the most common human skin cancer. As a post-doctoral fellow in our lab, you will have the opportunity to work within a team to perform basic science research that explores the cellular and molecular dynamics that controls these processes, using novel in vivo and genomic approaches. The projects employ a broad range of techniques, including mouse genetics, multi-photon live imaging, quantitative RNA fluorescent in situ hybridization, and single-cell RNA/ATAC sequencing.  Prior research experience using these techniques is a plus but not required. The candidate will also have opportunities to present his/her data at weekly lab meetings and at intramural and national/international conferences. The overall goal is to construct and perform scientific experiments that can be shared with the scientific community at large through peer-reviewed publications and speaking opportunities. In addition, the candidate will be given career development opportunities (e.g. grant-writing and public speaking skills) that are individually tailored to his/her long-term career goals. The ultimate goal is to create an experience that is rewarding and engaging for everyone in the lab and that fosters scientific and professional growth!

The candidate will be expected to perform the following:

1. Assist with mouse colony management, husbandry and genotyping
2. RNA in situ hybridization and immunohistochemical stains of mouse or human tissue followed by visualization using various microscopy techniques including multiphoton microscopy, confocal microscopy, and basic immunofluorescence/brightfield microscopy
3. Basic molecular biology techniques such as quantitative PCR, subcloning, and preparation of RNA for bulk and single-cell RNA sequencing
4. Preparation of single-cell suspensions from mouse skin for flow cytometry and FACS sorting
5. Basic tissue culture techniques using primary skin cells and cell lines
6. Embryonic and adult skin dissections
7. Intraperitoneal and gavage administration of soluble compounds (e.g. tamoxifen) to mice
8. Use basic software/statistical tools to analyze genomic data, including R packages for single-cell RNA sequence analysis
9. Assist with data analysis, interpretation, and generation of figure quality data for publication and/or presentations
10. Attend intra-mural and extra-mural conferences where he/she can present research data and build professional relationships
11. Review and present relevant literature at journal clubs or lab meetings
12. Attend weekly dermatology and/or pathology research in progress conferences as well as weekly lab meetings
13. Attend one-on-one meetings with the PI to review scientific data/progress and goals and to provide reciprocal constructive feedback
14. Prepare manuscripts of his/her primary research for publication
15. Assist with lab organization

Interested candidates should email a cover letter that briefly describes their personal and career goals as well as their research/scientific background, their CV, and at least 3 letters of reference to peggy.myung@yale.edu. 

A postdoctoral position is available immediately to study a novel tumor-targeting antibody for cancer therapy. Research in the lab is focused on developing novel approaches to cancer therapy by exploiting synthetic lethal vulnerabilities and leveraging tumor targeting strategies and fundamental mechanistic studies of cancer biology. Recent publications include Sulkowski Nature 2020 (PMID: 32494005) and Kaplan Science Translational Medicine 2019 (PMID: 31092693).

We offer a dynamic and stimulating work environment for conducting cutting-edge research and for facilitating career development. Interested candidates should have a strong research track record. While prior experience in cancer biology, molecular biology, and mouse tumor models is advantageous, we welcome researchers from all biomedical research backgrounds.

Qualified candidates should send their CV and contact information for at least two references to Peter Glazer, Departments of Therapeutic Radiology and Genetics, Yale School of Medicine at: peter.glazer@yale.edu

The Schlieker laboratory (https://medicine.yale.edu/lab/schlieker/) is seeking highly motivated researchers to join our collaborative and interdisciplinary team at Yale. Help us to characterize the role of nuclear envelope dynamics and nuclear protein homeostasis in relation to human disease. We also want to build the next generation of global scientific leaders, offering our scientists the mentoring, resources, and creative environment to launch successful careers.

We apply a broad range of interdisciplinary approaches including CRISPR-based genome wide screens, advanced life cell imaging, biochemical reconstitution and structural approaches. With these techniques, we investigate functional genetic networks operating within the nuclear envelope, monitor membrane dynamics both in vivo and in vitro, and mechanistically dissect molecular machines that sculp and remodel nuclear membranes. Ultimately, we want to understand how defects in these processes are tied to human pathology, informing corrective therapy.

Projects are available in these areas: (i) identifying the molecular function of Torsins (essential AAA+ ATPases) in the context of nuclear pore complex assembly (https://doi.org/10.1083/jcb.201910185); (ii) analyzing the function of chaperones in modulating phase separation and protein quality control in the nucleus. (iii) functional and molecular analysis of NOMO, a novel membrane-shaping protein (https://doi.org/10.1101/2021.01.28.428001).

Research environment: Being affiliated with two departments (Department of Molecular Biophysics and Biochemistry and Department of Cell Biology), we embrace collaborative approaches and provide a diverse and nurturing training environment. As a member of the Yale Nucleus Club, we hold regular joint lab meetings labs across three departments, offering exciting opportunities for intellectual exchange, collaborations and skill development in a vibrant scientific community. Postdocs will have access to an impressive variety of state-of-the-art core facilities as well as outstanding educational resources through the Yale Center for Teaching and Learning (https://poorvucenter.yale.edu/Postdocs).

Qualified candidates should have a PhD in biochemistry, cell biology or molecular biology and have strong communication and team skills.

If interested, please contact christian.schlieker@yale.edu with a copy of your resume.

A postdoctoral position is available immediately to apply the tools of chemical biology to characterize and target novel melanoma driver proteins. Techniques include peptide selection and preparation, chemoproteomics, and cell-based assays. Successful candidates will have a Ph.D. or equivalent with strong preparation in protein or peptide biochemistry, recombinant DNA technology, and cell and molecular biology. Chemical biology experience is preferred. We particularly welcome candidates from backgrounds underrepresented in science to apply.

The position is supported by funding from the Melanoma Research Alliance and the YCC Meyers Award Funds . The candidate will be part of a vibrant collaboration between the research groups of Dr. Ruth Halaban, Yale University Department of Dermatology, and Dr. Sarah Slavoff, Yale University Department of Chemistry. For representative recent publications, see PMID: 33357462, PMID: 33479206, PMID: 31040916, and bioRxiv preprint doi: https://doi.org/10.1101/2021.04.20.440286.

Interested candidates are encouraged to send a CV, description of research interests, and three letters of reference to:

Sarah Slavoff, Ph.D.

Department of Chemistry
Institute of Biomolecular Design and Discovery

Yale University

West Haven, CT 06511

Email: sarah.slavoff@yale.edu

The Department of Radiology and Biomedical Imaging at Yale University is seeking highly motivated postdoctoral associate to join our team at Payabvash Lab. The research focus is on application of deep-learning for automated assessment of brain CT and MRI scans in patients with stroke and brain injury. Our goal is to devise novel tools for diagnosis, outcome prediction, and risk-stratification of patients with cerebrovascular diseases, based on wealth of information extracted from medical images and clinical records.

Successful applicants will have the opportunity to work in close collaboration with Department of Biomedical Engineering, and Department of Neurology at Yale. We are working on a large cohort of multi-institutional multi-national datasets to address some of the most pressing needs in patients who are susceptible to brain injury. Postdocs are expected to develop and deploy deep neural networks for medical image analysis, utilizing the available datasets. The postdocs will also oversee and lead graduate students and RAs working in the lab.

Preferred qualifications include:

• PhD in computer science, electrical engineering, or biomedical engineering
• Experience with application of CNN for image classification and segmentation – preferably medical images
• Advanced programming experience and analytical skills
• A record of publication and/or conference presentations

Qualified candidates should submit a cover letter describing previous programming experience, CV, and three references to: The Department of Radiology and Biomedical Imaging at Yale University is seeking highly motivated postdoctoral associate to join our team at Payabvash Lab. The research focus is on application of deep-learning for automated assessment of brain CT and MRI scans in patients with stroke and brain injury. Our goal is to devise novel tools for diagnosis, outcome prediction, and risk-stratification of patients with cerebrovascular diseases, based on wealth of information extracted from medical images and clinical records.

Successful applicants will have the opportunity to work in close collaboration with Department of Biomedical Engineering, and Department of Neurology at Yale. We are working on a large cohort of multi-institutional multi-national datasets to address some of the most pressing needs in patients who are susceptible to brain injury. Postdocs are expected to develop and deploy deep neural networks for medical image analysis, utilizing the available datasets. The postdocs will also oversee and lead graduate students and RAs working in the lab.

Preferred qualifications include:

• PhD in computer science, electrical engineering, or biomedical engineering
• Experience with application of CNN for image classification and segmentation – preferably medical images
• Advanced programming experience and analytical skills
• A record of publication and/or conference presentations

Qualified candidates should submit a cover letter describing previous programming experience, CV, and three references to: Payabvash_lab@yale.edu

The Yale Center for Emotional Intelligence, part of the Child Study Center at the Yale University School of Medicine, conducts research and teaches people of all ages how to develop their emotional intelligence. Our work focuses on: (1) the development and impact of social and emotional skills among diverse populations, including education settings and organizations, and (2) the mechanisms by which social and emotional skills and training impact significant life outcomes.

We are looking for a Postdoctoral Associate to join our Mindfulness, Social Connectedness, and Psychological Well-Being Project Team. Our team is launching a randomized controlled trial (RCT) in the Fall of 2021 investigating the effects of Compassion Cultivation Training (CCT), Mindfulness-Based Stress Reduction (MBSR), and control group training on college student social connectedness/loneliness, and psychological health and well-being. We are implementing a biopsychosocial, multiple-levels-of-analysis approach that will index college student subjective experiences, social behavior, and biological functioning (e.g, cortisol and interleukin-6). The project goals are to test the efficacy of prosocially-oriented contemplative interventions (CCT) as compared to the more well-studied mindfulness-based interventions (MBSR) in promoting healthy, connected, and meaningful social lives for college students and beyond. We are also interested in understanding for whom the trainings are most effective (demographic moderators, including gender and racial/ethnicity identity) and why (biopsychosocial mediators of intervention effects). The results of this project will inform larger efforts to foster social health and psychological well-being in college students and other chronically stressed populations, including educators and medical professionals.

The postdoctoral associate will be responsible for contributing to: study design; data collection and cleaning; quantitative, qualitative, and mixed methods data analyses, including using machine learning and AI text-based analytic techniques; programing and troubleshooting online study projects on Qualtrics; liaising with participants and intervention trainers inside and outside of Yale University; preparing academic conference proposals; and attending routine meetings at the Yale Center for Emotional Intelligence with Yale staff and our collaborators, and other related tasks as needed. Dr. James Floman will oversee day-to-day work assignments and be the primary supervisor. The Director of Research, Dr. Christina Cipriano, will provide additional supervision and professional support.

Skills and Qualificiations

·         Qualified candidates will have recently completed a PhD in psychology or affective science

·         Specialization in mindfulness, meditation, and contemplative science, affective science and well-being, and/or compassion and prosociality/positive psychology interventions

·         Proficiency in SPSS, Mplus, R, and/or Python

·         Advanced data analysis including experience with structural equation modeling, growth curve modeling, multi-level modeling, and/or experience sampling methods

·         Experience with randomized control trials in psychological or cognitive science

·         Experience with research using biological markers such as cortisol and interleukin-6

·         Machine learning/AI approaches to analyzing open-ended text

·         Excellent time management skills, including comfort working under deadlines

·         Superior written and oral communication skills

·         Ability to work both independently and collaboratively

The anticipated start date is July 2021. The position may start remotely in accordance with Yale University guidance around COVID-19 until the university resumes regular on-campus operations, which is planned for August 1, 2021 and as determined by the business needs of the department.

In accordance with university requirements for a safe return to in-person university operations, all faculty, staff, and postdoctoral and postgraduate trainees will be required to be fully vaccinated against COVID-19 by August 1. For additional information, please visit https://your.yale.edu/work-yale/workplace-guidance/workplace-guidance-faqs.

To Apply

Please send a cover letter and CV to Dr. Annette Ponnock at annette.ponnock@yale.edu. Review of applications will begin immediately and continue until the position is filled. Please have contact information for three references and an academic writing sample available upon request.

ABOUT THE YALE CENTER FOR EMOTIONAL INTELLIGENCE

Emotions drive learning, decision-making, creativity, relationships, and health. The Yale Center for Emotional Intelligence uses the power of emotions to create a more effective and compassionate society. Helping children and adults develop emotional 

Postdoctoral positions are available in the Laboratory of Dr. Raul J Guzman, Chief, Division of Vascular and Endovascular Surgery at Yale University School of Medicine.

The research program focuses on investigating the mechanisms that control arterial disorders including calcification and restenosis. The laboratory uses multiple approaches including gene knockdown, overexpression, and deficiency in cell culture, ex vivo organ culture, small animal models, and transgenic mice. Its goal is to identify novel mechanisms that control pathologic arterial responses and to develop therapeutic agents to prevent them.

Qualified applicants are those who have earned a Ph.D. or equivalent degree with a strong background in vascular biology or related fields. The candidates should have prior experience with cell and molecular biology and small animal techniques. Ideal candidates will have the ability to independently design, execute and troubleshoot experiments. They will have the ability to collect, analyze and interpret data in preparation for manuscript publication. They will also possess the ability to communicate in English both verbally and in writing to present experimental findings at internal meetings and scientific conferences.

To apply for this position please submit your CV, a cover letter, and contact details of three references to yujun.cai@yale.edu 

A postdoctoral fellow is sought for a research position in an interdisciplinary vaccine research group. Fellow should have strong quantitative skills and a doctoral degree in epidemiology, global health, economics/econometrics, or another relevant quantitative discipline. PhD in lab sciences with experience in field or clinical work will be considered. Individual with the potential for leadership, a desire to cross interdisciplinary boundaries, and aptitude for developing an independent research portfolio will be strong applicants. Researcher in their first or second postgraduate research year is preferred, but third-year researcher will also be considered.

Examples of duties:

• Coordination of research efforts between different research sites, nationally and internationally
• Drafting grant proposals and protocols
• Primary and/or secondary authorship of original research manuscripts
• Mentoring of predoctoral researchers

Minimum qualifications:

• Doctoral degree in epidemiology, global health, economics/econometrics, or another relevant quantitative discipline
• Strong quantitative skills with data cleaning and analysis as well as manuscript drafting and publication
• High EQ and a strong focus on team-oriented research

Omer Research Group

Omer Research Group is involved with a diverse complement of vaccine research, ranging from field and clinical trials to epidemiological studies and studies on vaccine acceptance and policy. The group also maintains collaborative research relationships with vaccine immunology groups. The group is headed by Saad B. Omer, MBBS, MPH, PhD.

Research Group Environment and Philosophy

Omer Research Group works both domestically and internationally; the postdoctoral positions will focus on a variety of interdisciplinary projects having to do with vaccine research. This group also has an orientation towards strong mentoring and focuses on developing skills as well as the ability to lead an independent research program. We invest in mentee growth and have a culture of mutual support. The group fosters a rigorous scientific research environment but is cognizant of the importance of work-life balance - and works with members to strike a healthy balance between research and personal life.

Interested applicants should send their CV to omer.admin@yale.edu

Yale School of Medicine is seeking a highly motivated Postdoctoral Associate to join a collaborative effort between the laboratories of Laura Niklason MD, PhD (Adjunct Professor in the Departments of Anesthesia and Biomedical Engineering) and William Chang MD, PhD (Assistant Professor in the Department of Medicine and Section of Nephrology). The research project will focus on tissue engineering models of kidney disease. More specifically, the Associate will develop microfluidic devices to model and analyze tubular dysfunction in polycystic kidney disease. The Associate will be supervised by Drs. Niklason and Chang. We are seeking an enthusiastic and motivated scientist who will receive intensive mentorship and training in laboratory research techniques, critical thinking, and problem solving. The Associate will participate in manuscript publications, laboratory group meetings, and will gain critical experience presenting their research.  

Applicants for the position should have an MD, PhD, or equivalent with significant experience in biomaterials, biomedical engineering, or a related field. Experience in bioinformatics would be beneficial.

Application materials consisting of a cover letter and Curriculum Vitae should be submitted electronically to Dr. Chang (w.chang@yale.edu). The cover letter should include research interests, career goals, and contact information for three potential references. Review of applications will begin immediately and will continue until the position is filled.

Research in the Konnikova group is directed at studying the development and maintenance of mucosal immunity at barrier sites such as the intestine and placenta. We are interested in understanding how homeostasis is established and maintained in humans and what goes awry to cause disease such as necrotizing enterocolitis and inflammatory bowel disease in relationship to intestinal health and preterm labor in case of placental biology. We are seeking a motivated and dynamic postdoctoral candidate to join our team who is interested in applying cutting edge techniques including mass cytometry and single cell RNA sequencing in combination with cell biology and organoid approaches to studying development of human mucosal immunity at barrier sites. My group has access to the CyTOF and genomics cores at Yale as well as state-of-the-art cell and molecular imaging facilities. During this time, the successful applicant will obtain further training in translational research, in vivo model systems and a range of immunological techniques.

The candidate will be expected to have an MD, PhD, or MD/PhD with experience in immunology. Preference to candidates with involvement in human immunology will be given, but it is not a requirement. The successful candidate will be self-motivated and have the capacity for independent evaluation of the literature. Prior knowledge in primary cell isolation, flow cytometry, imaging techniques and single cell techniques would be an added benefit. For more information on our group, please visit our website – www.konnikovalab.com.

Interested applicants should send a brief statement of interest and curriculum vitae with contact information for three references to the Principal Investigator, Dr. Liza Konnikova – liza.konnikova@yale.edu.

The Hayman Lab, led by Thomas Hayman, MD, PhD, in the Department of Therapeutic Radiology at Yale University is recruiting a highly motivated and creative postdoctoral fellow.  We are a cancer biology lab that is focused on utilizing genetic approaches to understand and exploit resistance mechanisms to DNA damage. 

Our research program has a particular interest in studying the interplay between the cell intrinsic immune machinery and DNA repair processes using in vitro cell models, genetic screens (such as CRISPR and RNA interference), and animal models.  We have a strong translational focus that is founded in a preclinical mechanistic understanding of basic biological processes with the ultimate goal of shaping these discoveries into therapeutic strategies for cancer patients.

We are seeking a candidate who will contribute to the discovery and translation of biological processes that modulate tumor responses to DNA damaging therapies (e.g. radiation) and immunotherapy.  Interested applicants should hold a PhD. or M.D. with considerable laboratory experience and a strong background in cancer biology, molecular biology, genetics, radiation biology or other related fields.  Prior experience with in vivo animal tumor models, CRISPR/Cas9, IF/IHC and DNA damage assays is highly desired, but not a requirement.  The candidate should be self-motivated and have a proven track record of productivity.  Excellent written and oral communication skills are expected. 

How to Apply:

Candidates should send a Curriculum Vitae, a cover letter detailing research interests and career goals, and contact information for three references to Dr. Thomas Hayman (thomas.hayman@yale.edu).

The Yale Center for Emotional Intelligence, part of the Child Study Center at the Yale University School of Medicine, conducts research and teaches people of all ages how to develop their emotional intelligence. Our work focuses on (1) the development and impact of social and emotional skills among diverse populations, including education settings and organizations, and (2) the mechanisms by which social and emotional skills and training impact significant life outcomes.

We are looking for a Postdoctoral Associate to join the Adolescent Initiatives Team (PIs: Drs. Jessica Hoffmann and Rachel Baumsteiger). This team works on a range of projects, including (1) the development of a web-based app designed to measure students’ perceptions of school climate; (2) the development of a tool designed to assess students’ momentary emotions and emotion regulation at school; and, (3) the development and testing of the RULER and inspirED: two complementary social emotional learning initiatives for middle and high schools.

The postdoctoral associate’s primary responsibility will be to analyze data across projects. They will also be expected to support in other tasks related to the team’s research, such as the preparation of research articles, grant writing, and the design of future studies. Jessica Hoffmann and Rachel Baumsteiger will oversee day-to-day work assignments and be the primary supervisors. The Director of Research, Dr. Christina Cipriano, will provide additional supervision and professional support.

Skills and Qualifications

• Qualified candidates will have recently completed a PhD in psychology, education, or a related field

• Specialization or demonstrated interest in the study of adolescent development, emotions, and psychological assessment

• Excellent statistics skills, including experience conducting multi-level modeling

• Ability to communicate effectively (e.g., writing research papers, giving presentations)

• Strong project management skills

• Ability to work both independently and collaboratively; an interest in mentorship is preferred

The anticipated start date is July 2021. The position may start remotely in accordance with Yale University guidance around COVID-19.

To Apply

Please send a cover letter and CV to jessica.hoffmann@yale.edu and rachel.baumsteiger@yale.edu. Within your cover letter, please describe your level of familiarity with multi-level modeling.

Reviews of applications will begin immediately and continue until position is filled. Please have three letters of reference available upon request.

ABOUT THE YALE CENTER FOR EMOTIONAL INTELLIGENCE

Emotions drive learning, decision making, creativity, relationships, and health. The Yale Center for Emotional Intelligence uses the power of emotions to create a more effective and compassionate society. Helping children and adults develop emotional intelligence is central to the mission of the Center. To date, schools have been at the center of these efforts. RULER, the Center’s signature program, draws on leading pedagogical practices as well as advances in psychology and neuroscience, and it has been honed through years of classroom observation, interviews, and the most demanding evaluations. Creating awareness—both of self and others—about emotions and developing the skills of emotional intelligence can improve children’s prospects in life and contribute, in turn, to healthier, more compassionate families, workplaces, and communities. RULER does this by teaching adults and children the skills of emotional intelligence. Since 2005, more than 600 schools have implemented RULER, affecting the lives of over 500,000 students. Accordingly, we integrate emotional intelligence skill building, the basis of RULER, into their everyday practices and into classroom curricula across grade levels

Research in the Yimlamai Lab is directed at understanding the drivers of human liver disease, particularly in Pediatric diseases such as biliary atresia and non-alcoholic steatohepatitis. Our focus is in the cell biology of epithelial cells with their microenvironment and we are seeking a motivated, dynamic postdoctoral candidate who is interested in applying cell biology, organoid and animal model approaches to understanding fundamental mechanisms in liver biology. As a member of the Yale Liver center, lab members have access to the Morphology cores with State-of-the-art cell and molecular imaging facilities. During this time, the successful applicant will obtain further training on in vivo models as well as a range of cell and molecular biology techniques.

The candidate will be expected to have an MD, PhD, or MD/PhD with experience in cellular and molecular biology. Preference to candidates with involvement in liver pathophysiology will be given, but it is not a requirement. The successful candidate will have the capacity for independent evaluation of the literature. Prior knowledge in cell culture techniques, primary cell isolation/culture, flow cytometry and imaging techniques would be an added benefit. For more information on our group, please see our website – www.liverstemcells.org.

Interested applicants should send a brief statement of interest and curriculum vitae with contact information for three references to the Principal Investigator, Dr. Dean Yimlamai - dean.yimlamai@yale.edu.

The Yale Center for British Art (YCBA) is offering a Postdoctoral Associate position of up to three-years duration in the Curatorial Division. The position is for recent recipients of the PhD (degree granted within the last three years) in the field of British art. The PhD must be completed by the time the position begins and it is expected that the research associate will pursue long-term professional employment during the period of hire.

The Postdoctoral Research Associate will report to the Deputy Director and Chief Curator and contribute to the activities of the Curatorial Division. Specific projects will include the development of an exhibition on the artist Hew Locke alongside a complimentary collections display selected in collaboration with the artist. The Postdoctoral Research Associate will help to curate a display of works by Marc Quinn, undertake research on works in the collection, and collaborate with the Deputy Director and Chief Curator on the reinstallation of the Center’s permanent collection. Additional duties will include writing labels and developing scholarly programs and teaching materials in support of major projects. The postholder will occasionally mentor student interns and participate in programs organized by the Curatorial Division. One day per week will be allotted to pursue personal research in the postholder’s own area of specialization. Limited funds will be available to enable the Postdoctoral Research Associate to present annually at a professional conference.

The closing date for applications is June 7, 2021. Interviews are expected to take place in July.

Application materials should be sent by email and need to include: cover letter, CV, recent writing sample. Two letters of reference should be emailed directly from the referees. Please send all application materials to ycba.paintings@yale.edu, with the subject line Postdoctoral Research Associate Application. For enquiries about the position, please contact martina.droth@yale.edu .

We have an opening for a talented and highlight motivated Postdoc for a 1-year (with potential extension for 2-years) position. The Benveniste lab in the Department of Anesthesiology at Yale University focuses on translational research of neurodegenerative disorders such as cerebral small vessel disease and Alzheimer’s disease Specifically we study the roles of cerebrospinal fluid flow dynamics and glymphatic-lymphatic coupling and explore novel disease modifying therapies. The lab uses a combination of magnetic resonance imaging (MRI), physiological interventions in transgenic and surgical rodent models together with molecular/histological tools.

The successful candidate will have hands-on experience in a variety of in vivo and histological processing techniques in particular multiplex immunohistochemical staining of brain and lymph node tissue to support our various projects. The candidate must be proficient in immunohistochemistry/ immunofluorescence staining, perform statistical calculations and data analysis. As a member of the research staff, you will assist Dr. Koundal. Dr. Benveniste and research staff in the lab with the following:

Principal Responsibilities:

• Assist lab staff with research experiments including non-survival and survival surgery (e.g., lymph vessel ligations, CSF catheter implantation, arterial cannulations), brain dissection and slice preparation
• Using and understanding a wide variety of histological technique
• Working with and handling research animals
• Perform multiplex immunohistochemical staining of rodent brain and lymph node tissue in support of various research projects. Also, must have prior experience in fluorescence microscopy
• Participate in laboratory meetings and read literature applicable to the research area
• Help with lab organization and other support duties relating to lab operations, as required
• Other duties as assigned.

Preferred Qualifications:

• Bachelor’s degree in Biology or a related field
• Prior experience working in a research laboratory
• Excellent analytical, communication, problem solving, and organizational skills

Ability to work both independently and as a team memberAble to learn and perform new techniquesExperience in multiplex immunohistochemistry/ immunofluorescence staining of rodent brain and lymph node tissue.

To Apply:

Please submit a CV and cover letter stating your interest in the position to sunil.koundal@yale.edu or helene.benveniste@yale.edu 

The laboratory of  Dr. Vikki Abrahams, PhD in the Department Obstetrics, Gynecology & Reproductive Sciences at Yale School of Medicine is looking to recruit a motivated Postdoctoral scientist.

The Abrahams Lab focuses on understanding the role of innate immune Toll-like receptor, Nod-like receptor and inflammasome family members in placental, fetal membrane, and maternal-fetal immune responses to infectious and non-infectious stimuli, and their role in regulating pregnancy outcome, including those complicated by infections and by autoimmune diseases. The lab uses basic and translational approaches; primarily in human models systems and samples, but also using animal models. The current position will involve studying the mechanisms by which antiphospholipid autoantibodies trigger placental trophoblast inflammation and communication with the maternal vasculature. The position is for 2 years initially and is anticipated to start summer-fall 2021. 

Applicants should have a PhD in a relevant field such as Immunology; Reproductive Sciences; or Cellular and/or Molecular Biology. Prior Reproductive Immunology and/or Reproductive Biology experience is preferred but not essential. Applicants should have skills that include, but are not limited to cell culture, Western blot analysis, ELISA, and qRT-PCR.

Candidates should be enthusiastic, highly organized, self-motivated, hard-working and reliable, with excellent interpersonal and written and oral communication skills. Applicants must have good attention to detail and problem-solving skills, be able to multi-task, and be able to perform both independently as well as in a team environment. Successful applicants will have a strong track record of research productivity, presentations, and publications.

Applicants should email: 1) a Curriculum Vitae; 2) contact information for three references; and 3) a description of their research background and interests and career goals to Dr. Vikki Abrahams (vikki.abrahams@yale.edu)

The laboratory of Dr. Kevan Herold in the Immunobiology Dept at Yale University is looking to recruit a motivated Postdoctoral scientist to join our team.  

The Herold lab advances immunology through its focus on understanding the mechanisms of autoimmune disease, primarily Type 1 diabetes. Our studies are translational but involve both the use of human samples and animal models, including humanized mice, where needed to address mechanistic questions. The position is focused on understanding the changes in autoreactive T cells following immune therapies, specifically to identify changes in their numbers, phenotypes and activation, and the pathways that are modulated by the therapy. The samples are acquired from patients receiving anti-T and B cell therapies. The qualified candidate will receive the following while in this position:

Training – The individual will receive training in methods used to analyze research samples by flow cytometry, molecular studies, and with cell culture techniques. If the postdoc has not previously had training in bioinformatics, he/she will be encouraged to learn these methods through course work or other educational opportunities at the University.

Mentoring – The PI (Dr. Herold) will mentor the trainee. In addition, there are members of the laboratory who will provide training in methods.

Education - A PhD in relevant fields such as Immunobiology is required and skills that include, but are not limited to cell culture, flow cytometry, and basic molecular methods. Experience with more advanced molecular methods such as RNA-seq and single cell RNA-seq are preferred.

Interested candidates should email their CV and cover letter, with the words “Postdoc Opportunity in the Herold Lab” in the subject line, to dana.kalina@yale.edu to be considered. 

A postdoctoral associate position in mathematical/statistical modeling of SARS-CoV-2 immune responses and correlates of protection is available within the Department of Epidemiology of Microbial Diseases at the Yale School of Public Health in collaboration with the Department of Biology and the Emerging Pathogens Institute and at the University of Florida.

Environment

The Department of Epidemiology of Microbial Diseases at the Yale School of Public Health has a tradition of applying advanced laboratory and analytical approaches to integrated community and patient-based investigations for the purpose of delineating the transmission dynamics and evaluating interventions to emerging and neglected infectious diseases, such as Zika, dengue and leptospirosis. It has played a leading role in the public health and research response to the COVID-19 pandemic in the US and internationally.

Job description
We are seeking a postdoctoral associate to analyze longitudinal data from a cohort of individuals infected by SARS-CoV-2. The Yale Schools of Public Health and Medicine and the University of Florida are collaborating to study the dynamics of immune responses to SARS-CoV-2 infection and vaccination. The postdoctoral associate will be based at the Yale School of Public Health and work under the supervision of both Dr. Albert Ko, Department Chair of Epidemiology of Microbial Disease at the Yale University School of Public Health, and Dr. Derek Cummings, Professor in the Department of Biology and the Emerging Pathogens Institute at the University of Florida. There will also be opportunities to work with other members of the project team, including Dr. Wade Schulz, Assistant Professor and Director of Informatics and the Center for Computational Health at Yale. The overall goal of the research is to describe the long-term trajectory of the SARS-CoV-2 pandemic and the effect of vaccines and to refine understanding of the contribution of immune status and function to the risk of multiple outcomes upon SARS-CoV-2 infection. The main research objectives for the postdoctoral position are to develop mathematical and statistical models to analyze longitudinal measurements of immune responses to SARS-CoV-2, measure vaccine effectiveness, identify correlates of protection from infection and disease and understand the contribution of other individual level factors associated with immune responses and risk of COVID-19.

Required skills and qualifications:

• PhD in one of the following areas: epidemiology, mathematics, statistics, immunology, physics, computer science, population biology or a similarly quantitative discipline.
• Research experience with mathematical and/or statistical models.
• Excellent verbal and written communication skills.
• Strong interest in infectious disease epidemiology.
• Ability to collate and analyze data, interpret and present results to a high standard using a range of specialized research techniques.
• Good knowledge of R.
• Experience in communicating research findings to a non-specialist audience.
• Ability to work independently but also as part of a larger interdisciplinary research team.

This will be a one-year appointment with the possibility to extend, should both parties agree.

To apply, please submit a CV, statement of interest, and contact information for 3 references.  Please apply online: http://apply.interfolio.com/85223

For questions, please email Ryan Borg (ryan.borg@yale.edu).

The Developmental Affective Neuropharmacology (DAN) Lab and Pediatric Treatment Resistant Depression Program at the Yale Child Study Center seek a highly qualified post-doctoral associate to participate in cutting-edge clinical research on adolescent depression and suicidality. This NIMH-funded work assesses novel interventions for treatment-resistant affective disorders in adolescents and incorporates assessment of neuroimaging biomarkers into clinical trial designs.

The DAN Lab at Yale is hiring a post-doctoral associate for training in the context of a clinical trial that tests ketamine as an anti-suicidal agent in teenagers with treatment resistant depression and suicidal thinking, incorporating fMRI imaging to identify biomarkers predictive of treatment response. Responsibilities will include conducting diagnostic and clinical assessments of teenagers with depression and suicidality, providing oral and written clinical feedback to families, and conducting longitudinal assessments of mood and cognition, as well as other research activities within the Yale Pediatric Treatment Resistant Depression Program. Applicants should have experience in the clinical and diagnostic assessment of adolescents with affective disorders; clinical trial experience in adult or pediatric depression is appreciated, but not required.

As part of the broader study, the post-doctoral associate will be part of an interdisciplinary research team conducting a wide range of longitudinal assessments, including diagnostic, observational, and fMRI measures. As part of the appointment, there will be opportunities for supervising post-graduate associates with clinical training, as well as potential for participation in research dissemination through publication or conference presentations. There may also be opportunities to accrue clinical hours for those who are pursing licensure. We are seeking a two-year commitment (all initial appointments are one year, with the potential for renewal).

The Liu Research Lab in the Department of Pathology at Yale University has an opening for a postdoctoral position.  The lab is focused on understanding the pathogenesis and immunobiology of human solid tumors using quantitative pathology, genetic/epigenetic analysis, in vitro/in vivo cell models, and molecular biology to interrogate relevant immunomodulatory pathways and identify determinants of sensitivity and resistance to treatments, as well as to develop novel therapeutic approaches for cancer. Our lab has access to cutting-edge technology and has unique opportunities to develop translational research projects in human liver and other GI cancers.  More information can be found at https://medicine.yale.edu/lab/chen_liu/research/

We are looking for a highly motivated individual interested in studying cancer immunology and/or cancer epigenetics. Interested applicants should hold a Ph.D. or MD/Ph.D. degree and a strong background in the field of immunology and/or translational oncology. The candidate should be self-motivated with a proven track record of productivity.  In addition to individual projects, the lab encourages a collaborative and positive working environment with other lab members and throughout the University and Cancer Center.

The competitive candidate should have knowledge and expertise in the following areas:

1. Immune-oncology and immunomodulatory therapies
2. Solid tumor oncology, cancer epigenetics, and translational pathology
3. Advanced cancer diagnostics and immune-based anti-cancer therapeutics
4. Computational analysis of images and large datasets (optional, but preferred)

Candidates with the following qualifications will be given preference:

1. Interest and expertise in the field of immune-oncology/cancer epigenetics
2. Productivity, quality of previous projects and independence
3. Ability and interest to work in translational research within a multidisciplinary team

Qualified candidates who are interested in applying should e-mail an application package, including; statement of interest, CV, and contact information for three references. Please send your application package to Drs. Chen Liu (chen.liu@yale.edu) or Kien Pham (kien.pham@yale.edu) and in the subject line include your last name and reference to the job posting.

We are seeking postdoctoral fellows to join the laboratory of Dr. Grace Chen in the Department of Immunobiology. The Chen lab investigates the mechanisms and regulation of circular RNAs (circRNAs), a newly identified class of ubiquitous RNAs in essentially all eukaryotes and some viruses. Thus far, circRNAs have been found to function as miRNA sponges, regulate transcription, and act as templates for translation. However, there are still many unanswered questions: What other functions do circRNAs possess? How are circRNAs degraded? What are their interacting proteins? Specifically, we aim to understand how different layers of regulation including RNA modifications and cellular localization affect RNA function to enable new insights into both normal function and how dysregulation leads to disease.

The Chen Laboratory applies molecular, cellular, and chemical biology techniques coupled with next-generation sequencing to address these questions. We aim to generate novel therapies based on our new insight about circRNA function and regulation. For more information, visit gracechenlab.org.

Applicants should have recently completed a Ph.D. degree in molecular biology, chemical biology, immunology or genomics. High priority will be given to those candidates with strong backgrounds in RNA or chemical biology.

Interested applicants please send a brief statement of interest and curriculum vitae with contact information for three references to the PI Dr. Grace Chen at ye.grace.chen@yale.edu.

Due to the COVID-19 pandemic, please submit applications via email to   mcp.lab@yale.edu 

Submit your application with the subject line: LAST NAME_Position Title (e.g., SMITH_Clinical Post- Doc). For additional questions, interested applicants should contact mcp.lab@yale.edu or call (203) 737-4586.

Direct applications to:

James McPartland, Ph.D.

Professor of Child Psychiatry and Psychology Director, Yale Developmental Disabilities Clinic

Principal Investigator, Autism Biomarkers Consortium for Clinical Trials

http://www.asdbiomarkers.org http://www.autism.fm http://www.mcp-lab.org