Yale Postdoctoral Positions

Yale University’s Nondiscrimination/Title IX Statements

Thank you for investigating postdoctoral opportunities at Yale.  Many faculty do not advertise open positions in their research groups, and you are encouraged to contact them directly to inquire about the possibility of training with them.  Other faculty advertise open positions in scholarly journals in their fields.  Finally, some post job openings on our website, and these positions are listed below.  Please click the links below to read more about each position and to find contact information for applying for the job.

Once you find a postdoctoral position your Yale department will contact you to begin the formal hiring process and to assist you in applying for an immigration visa to enter the United States if you require one.  Information about the visa process may be found at the Yale Office of International Students and Scholars website.

In accordance with university requirements for a safe return to in-person university operations, all faculty, staff, and postdoctoral and postgraduate trainees will be required to be fully vaccinated against COVID-19 by August 1. For additional information, please visit Yale University’s Office of the President . Read Here

Postdoctoral position in Psychiatric Genetics (Gelernter Lab)
Posting Date: July 23, 2021

A postdoctoral position is available for a highly motivated graduate student to join a productive and collaborative research group working on the genetics of psychiatric illness – especially PTSD and substance use disorders. Work will focus on (1) genetics of posttraumatic stress disorder, depression and anxiety, substance use disorders, and many related psychiatric traits in the uniquely-informative Million Veteran Program dataset; and (2) Psychiatric Genomics Consortium projects including these traits, and (3) studies in non-European populations. Through these and several other current projects, we explore large datasets including the Million Veteran Program and the Psychiatric Genomics Consortium. Other projects include a pharmacogenomics clinical trial for depression taking place in the VA system; a study of methamphetamine genetics in Thailand; a new mental health biobank project in the MVP; and studies of epigenetics of psychiatric traits.

The ideal candidate should hold an MD or PhD, and have a strong background in human genetics, including knowledge of genomewide methods, including GWAS and post-GWAS analysis; and comfort with bioinformatics. The candidate should also be able to work cooperatively with peers at Yale and with many other collaborators nationally and internationally; and bring research to publication. Faculty in our closely-collaborative division at Yale School of Medicine includes Drs Renato Polimanti, Janitza Montalvo-Ortiz, and Daniel Levey. Start date is flexible. Applicants should preferably have US citizenship or permanent residency.

Please send application (including CV and contact information for at least three references) by email to Prof. Joel Gelernter at joel.gelernter@yale.edu<mailto:joel.gelernter@yale.edu>

Postdoctoral position with the Center for Outcomes Research and Evaluation (CORE)
Posting Date: July 23, 2021

The Yale/Yale New Haven Hospital Center for Outcomes Research and Evaluation (CORE) is a leading national outcomes research center dedicated to transforming healthcare for the betterment of people and society by leveraging data, analytics, and technology. We have assembled a talented, multidisciplinary group who are committed to developing solutions to the practical needs of medicine and healthcare. Our organization combines the highest academic ideals with a pragmatic approach that emphasizes the production of useful knowledge. We are distinguished by our creativity, dedication, experience, and skills – and our commitment to having our work make a tangible difference to patients, the public, and society. For additional information on CORE, please visit our website: www.medicine.yale.edu/core.

CORE is recruiting a Postdoctoral Associate for its ongoing research program in computational health. The program is recruiting candidates with coding experience in Python and R, with a specific background in analytics on large relational datasets and the electronic health record (EHR). The specific skills include masters or doctoral training in computer science/informatics with an understanding of basics of informatics, and distributed computing with Spark (using Python or R). Successful candidates will participate in a range of research projects spanning various disease conditions with the opportunity to work with leading investigators in the space working on the next generation of knowledge generation in medicine. Career development will be supported through scholarly contributions, including research publications and presentations at national meetings. A PhD or equivalent is a requirement for this position; a background in healthcare analytics is preferred, but not required. The position is currently being offered for 2 years, with the option for extending beyond that time. The renumeration for the position is in line with Yale’s institutional standards.

Interested applicants should send a brief statement of interest and curriculum vitae with contact information for three references to kendall.getek@yale.edu.

Postdoctoral position in Omics of Psychiatry (Levey Lab)
Posting Date: July 23, 2021

Postdoctoral position for a highly motivated graduate student to join the Yale Psychiatry Division of Human Genetics, a productive and collaborative research environment with a focus on the genetics of psychiatric illnesses, behavioral phenotypes, and other complex traits founded by Dr. Joel Gelernter. The successful candidate will work with Dr. Daniel Levey on projects funded by the Brain & Behavior Research Foundation and the U.S. Department of Veterans Affairs, investigating the genetics of depression and anxiety disorders and related psychiatric traits in the VA Million Veteran Program dataset (one of the world’s largest and most informative biobanks) and the Psychiatric Genomics Consortium (the largest experiment in the history of biological psychiatry). Additional opportunities will include the analysis of a growing sample in the deeply phenotyped Yale-Penn cohort with genetics, RNAseq, and epigenetic data. Collaborations with other investigators within the division will be strongly encouraged.

Applicants must have or be about to be awarded a Ph.D. and/or M.D. The ideal candidate will have a strong background in human genetics or transcriptomics, including knowledge of genome-wide methods or RNAseq, including GWAS and downstream in-silico analyses and comfort with bioinformatics. The candidate should also be able to work cooperatively with peers at Yale and with many other collaborators nationally and internationally, and bring research to publication. The start date is flexible.

Please send your application (including CV and contact information for three references) by email to Dr. Levey at daniel.levey@yale.edu<mailto:daniel.levey@yale.edu> with Postdoctoral Associate in the title.

Postdoctoral position in Wildlife Molecular Ecology at Yale University
Posting Date: July 16, 2021

The Applied Wildlife Ecology (AWE) Lab in the Yale School of the Environment invites applications for a Postdoctoral Associate in Wildlife Molecular Ecology. The successful candidate will assist with protocol develop and implication leverage existing carnivore fecal samples as well as future collected soil and snow samples to understand spatial and temporal variation in prey consumption and availability. This work contributes to a new National Science Foundation-funded project (#2140322) on risk management in Detroit coyotes under the supervision of Prof. Nyeema C. Harris. At the frontier of behavioral and urban ecology, results from this project will garner new insights on how resources govern risk assessment, discrimination, and mitigation in apex predators living in cities where 81% of US residents live.

The ideal candidate has a Ph.D. focusing on topics in molecular ecology with exceptional research, writing, and verbal communication skills as well as an inclusive and flexible approach to collaborating with a diverse team of individuals and organizations. Experience with next-generation sequencing, metabarcoding, and eDNA are required. This is a one-year position with an expected reappointment for two additional years upon outstanding performance. The hire will be expected to perform sample processing and molecular analyses, co-author papers, mentor students, and contribute to public engagement and efforts to broaden participation. In addition to a competitive salary and full research support, the successful candidate will receive an annual professional development budget for additional trainings and scouting trips for future research based on their interests.

Yale values diversity among its students, staff, and faculty and strongly encourages applications from minoritized people especially BIPOC scholars and persons with disabilities. Consideration of applicants will begin immediately with the start date negotiable between September 2021 - January 2022.

Interested candidates should email a cover letter and their CV (hyperlink publications) along with a contact list of at least three references and “Coyote Molecular Postdoc” in the subject line to Nyeema C Harris, PhD, Associate Professor of Wildlife and Land Conservation at nyeema.harris@yale.edu.

 
Postdoctoral position in the Department of Emergency Medicine (Gettel Lab)
Posting Date: July 9, 2021

Cameron Gettel, MD, MHS, Assistant Professor, Clinician Scientist, in the Department of Emergency Medicine is actively seeking a Postdoctoral Associate to add to his growing team. This is a new program where Dr. Gettel plans to blend academic emergency medicine, health services research, and health policy as it relates to the growing geriatric population, including persons living with dementia and their caregivers. See duties and qualifications below.

Job Duties

The initial appointment is one year and renewable for up to six years total, with preference given to those who can commit to at least two years in the position.

The position includes opportunities for professional development and interdisciplinary training, as well as the opportunity to be part of the large and vibrant community of health services researchers at Yale University, Department of Emergency Medicine.

  1. Screening, enrollment, medical record data abstraction of in-ED research participants
  2. Secondary data analyses of datasets including HCUP, MCBS, and NHATS/NSOC among others
  3. Coordination of research efforts between sites
  4. Drafting grant proposals and protocols
  5. Primary and/or secondary authorship of original research manuscripts

Qualifications and Skills

  • Doctoral degree (MD or PhD) with interest in mixed methods research, health services research, geriatrics
  • Strong quantitative skills with data cleaning and analysis as well as manuscript drafting and publication
  • Focus on team-oriented research

Application Process

Review of applications will begin immediately and will continue until the position is filled. If interested, please send CV, cover letter and references to Dr. Cameron Gettel at cameron.gettel@yale.edu and Jackie Santana at jackeline.santana@yale.edu.

The anticipated start date is September 2021. In accordance with university requirements for a safe return to in-person university operations, all faculty, staff, and postdoctoral and postgraduate trainees will be required to be fully vaccinated against COVID-19 by August 1. For additional information, please visit https://your.yale.edu/work-yale/workplace-guidance/workplace-guidance-faqs.

Postdoctoral position in the Department of Neuroscience (Liang Lab and Crair Lab)
Posting Date: July 9, 2021

We are looking for a postdoctoral associate to join a collaborative project between the laboratories of Dr. Liang Liang and Dr. Michael Crair in the Department of Neuroscience at Yale School of Medicine. The project will focus on understanding how neural activity contributes to the establishment of thalamic visual function during development. The Liang lab has established an advanced in vivo imaging platform for studying the detailed functional and spatial organization of the visual thalamus in adult mice. The Crair lab has extensive experience imaging and manipulating neural activity in early postnatal mice, and has identified characteristic spatiotemporal patterns of retinal activity that guide neural circuit development. The postdoctoral associate is expected to bridge strengths from both labs to unveil the mechanisms underlying the development of functional selectivity in the early visual system. This position is funded by a Kavli Institute Innovative Research Award. The candidate is expected to lead the project and will be co-mentored by Dr. Liang Liang and Dr. Michael Crair.

An ideal applicant will be someone who can demonstrate the following:

Essential

  • The candidate should be in his/her last year of a PhD program in Neuroscience, Biology or related field, or within 1 year of receiving his/her PhD degree. 
  • An outstanding record of research and scholarly activity.
  • A demonstrable commitment to scientific discovery.
  • Be creative, thoughtful, strongly self-driven and well organized.
  • Have skills and experience in advanced neurophysiological techniques and quantitative data analysis.
  • Have skills and experience with complex surgery in model organisms.

Desirable

  • A good track record of securing fellowship and research funding.
  • In-depth knowledge of a programing language.
  • A good knowledge of the visual system.
  • Have skills and experience in two-photon calcium imaging and image processing

Interested candidates should contact Dr. Liang Liang (liang.liang@yale.edu) and Dr. Michael Crair (michael.crair@yale.edu). The application should include: (1) CV; (2) A brief description of research interests and motivation; (3) Contact information for 3 references.

Postdoctoral position in innate immunity and host-virus interactions (Foxman Lab)
Posting Date: July 7, 2021

The Foxman lab at the Yale School of Medicine is seeking postdoctoral researchers to join our team investigating innate immunity, host-virus interactions, and post-injury tissue repair in the human respiratory tract. Our lab spans the basic to translational spectrum, using patient samples, primary human cells, and organoid models, and techniques such as transcriptomics, proteomics, and single cell RNA Seq.  Background/interest in the following areas a plus: immunology, virology, next generation sequencing, single cell analysis. For more information about our recent work on host-virus interactions in the human respiratory tract, including studies of rhinovirus, influenza, and SARS-CoV-2, see our lab website at https://medicine.yale.edu/lab/foxman/.  

Our lab is in the Yale Department of Laboratory Medicine, and is affiliated with the Yale Department of Immunobiology, affording candidates access to a large network of colleagues doing exciting research and outstanding career development opportunities such as participation in departmental retreats, research in progress talks, and career development programming.  Dr. Foxman is also deeply committed to professional development and creating a plan that enables each post-doc to reach their career goals.

Please email statement of interest, C.V., and names of three references to ellen.foxman@yale.edu.

Requirements: PhD, MD, or MD/PhD and relevant training and publication record.

Forest Carbon in Southern New England Postdoctoral Associate
Posting Date: July 6, 2021
The Forest School at The Yale School of the Environment (YSE) invites applications for a Postdoctoral Associate in Forest Carbon. The successful candidate will assess forest carbon dynamics as they relate to natural disturbance and forest products, with a focus on southern New England. The candidate will work under the mentorship of faculty at The Forest School within YSE, and data from the Yale Forests and Great Mountain Forest will be available. Professors Mark Bradford and Yuan Yao will jointly serve as the primary supervisors, and other faculty at The Forest School will serve as collaborators.
 
The forests of southern New England have received significant attention in recent years for their potential as nature-based climate solutions. However, the carbon dynamics of these forests are highly complex and influenced by past land use, stand dynamics, invasive species, changing climate, and carbon tradeoffs related to forest products. Political debate has often simplified to two alternatives: active management and no management, yet the reality is far more complex. The person in this position will investigate the risks and longevity of carbon stored in forests and forest products in the region in the context of changing forests.
 
Results of this project will include peer-reviewed publication(s) and policy briefs related to carbon stability in southern New England’s forests as it relates to disturbance, stand dynamics, and management. The successful candidate will also investigate the carbon tradeoffs of local forest products and lead the development of best management practices for carbon as a management objective in southern New England forests, while working with a collaborative team of faculty and graduate students at The Forest School focused on forest carbon. We expect this research will better our understanding of the climate mitigation and adaptation of regional forests.
Support for this postdoctoral position comes from the Joseph Steven Taylor Fund at YSE.
 
The position is a one-year appointment with the possibility of two additional years of renewal contingent upon satisfactory performance and availability of funding. Candidates who have a Ph.D. degree in forestry or related fields with peer-reviewed publications related to silviculture and/or forest carbon and statistical modeling/ life-cycle assessment are highly encouraged to apply.
 
Consideration of applicants will begin immediately, but applications will be accepted until July 30, 2021. The start date of the position is negotiable, with a target of September 1, 2021.
 
Interested candidates should email a cover letter and their CV, along with a list of at least three references to Mark Bradford at mark.bradford@yale.edu
 
Application Deadline: July 30th 2021
Anticipated Start Date: September 1st 2021
Postdoctoral position at the School of Public Health (Aksoy Lab)
Posting Date: July 6, 2021

We are inviting motivated Postdoctoral Scientists to join our group to study the physiology, and the molecular and genetic mechanisms involved in host-pathogen interactions in the tsetse fly-African trypanosome system. We study the role of the fly immune system and the influences of tsetse’s endosymbiotic bacteria in the parasite infection process.  We also investigate parasite mediated mechanisms that modify tsetse’s vector competence efficiency and influences the transmission success of trypanosomes to the next mammal in fly saliva. Finally, we are developing transmission blocking vaccines that target antigens present on the parasites in saliva that are deposited to the mammalian bite site.

We are looking for highly motivated scientists trained in a related field such as entomology, microbiology or immunology.  Our lab provides a collaborative environment and multi-disciplinary training for scientific and career development. Our lab has a track record of training postdoctoral researchers: our postdocts have international conference presentations and first authored original articles in high impact journals. We also have extensive international collaborations with researchers in Africa which provide a rich training environment for our researchers in global health.

The successful candidate will likely have (a) a recent (,4-years) PhD degree in entomology, microbiology or immunology or a related discipline; (b) a track record of research productivity , as evidenced by first authored original publications in high quality peer-reviewed journals; (c) experience in–omics based technologies, and parasite or insect cultures; (d) experience with BSL2 procedures; (e) independence to lead a project as well as willingness to work in a team; (f) an open mind to learn new methods from collaborators and (g) good scientific presentation and writing skills. Previous experience in immunology, parasitology and bioinformatics are preferred. Salary and benefits are according to Yale and NIH guidelines.

Interested candidates may send a CV, personal statement and contact information for three references to Serap Aksoy (serap.aksoy@yale.edu).  Interested candidates can obtain additional information on our work https://ysph.yale.edu/profile/serap_aksoy/.  Below are a few of our recent publications.

1. Aksoy E, Vigneron A, Bing X, Zhao X, O’Neill M, Wu YN, Bangs JD, et al. (2016) Mammalian African trypanosome VSG coat enhances tsetse’s vector competence. Proc Natl Acad Sci U S A 113: 6961-6966.

2. Bing X, Attardo GM, Vigneron A, Aksoy E, Scolari F, Malacrida A, Weiss BL, et al. (2017) Unravelling the relationship between the tsetse fly and its obligate symbiont Wigglesworthia: transcriptomic and metabolomic landscapes reveal highly integrated physiological networks. Proc Biol Sci 284.

3. Vigneron A, O’Neill MB, Weiss BL, Savage AF, Campbell OC, Kamhawi S, Valenzuela JG, Aksoy S. Single-cell RNA sequencing of Trypanosoma brucei from tsetse salivary glands unveils metacyclogenesis and identifies potential transmission blocking antigens. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2613-2621.

4. Michalkova V, Benoit JB, Weiss BL, Attardo GM, Aksoy S (2014) Vitamin B6 generated by obligate symbionts is critical for maintaining proline homeostasis and fecundity in tsetse flies. Appl Environ Microbiol 80: 5844-5853.

5. Weiss BL, Savage AF, Griffith BC, Wu Y, Aksoy S (2014) The Peritrophic Matrix Mediates Differential Infection Outcomes in the Tsetse Fly Gut following Challenge with Commensal, Pathogenic, and Parasitic Microbes. J Immunol 193: 773-782.

6. Vigneron A, Aksoy E, Weiss BL, Bing X, Zhao X, Awuoche EO, O’Neill MB, et al. (2018) A fine-tuned vector-parasite dialogue in tsetse’s cardia determines peritrophic matrix integrity and trypanosome transmission success. PLoS Pathog 14: e1006972.

7. Weiss BL, Wang J, Maltz MA, Wu Y, Aksoy S. Trypanosome infection establishment in the tsetse fly gut is influenced by microbiome-regulated host immune barriers. PLoS Pathog. 2013;9(4):e1003318.

Postdoctoral position in Human Systems Immunology(Konnikova)
Posting Date: June 27, 2021

Research in the Konnikova group is directed at studying the development and maintenance of mucosal immunity at barrier sites such as the intestine and placenta. We are interested in understanding how homeostasis is established and maintained in humans and what goes awry to cause disease such as necrotizing enterocolitis and inflammatory bowel disease in relationship to intestinal health and preterm labor in case of placental biology. We are seeking a motivated and dynamic postdoctoral candidate to join our team who is interested in applying cutting edge techniques including mass cytometry and single cell RNA sequencing in combination with cell biology and organoid approaches to studying development of human mucosal immunity at barrier sites. My group has access to the CyTOF and genomics cores at Yale as well as state-of-the-art cell and molecular imaging facilities. During this time, the successful applicant will obtain further training in translational research, in vivo model systems and a range of immunological techniques.

The candidate will be expected to have an MD, PhD, or MD/PhD with experience in immunology. Preference to candidates with involvement in human immunology will be given, but it is not a requirement. The successful candidate will be self-motivated and have the capacity for independent evaluation of the literature. Prior knowledge in primary cell isolation, flow cytometry, imaging techniques and single cell techniques would be an added benefit. For more information on our group, please visit our website – www.konnikovalab.com.

Interested applicants should send a brief statement of interest and curriculum vitae with contact information for three references to the Principal Investigator, Dr. Liza Konnikova – liza.konnikova@yale.edu.

Wu Tsai Postdoctoral Fellowship
Posting Date: June 23, 2021

Come join a community dedicated to understanding the mind and cognition through integration across disciplines, organisms, and scales.

The Wu Tsai Postdoctoral Fellowship program at Yale seeks scientists who are excited about frontiers in interdisciplinary neuroscience and who represent a diversity of identities, including those from historically underrepresented backgrounds in science.

Apply to one of four priority co-mentored projects, carefully selected for their science and inclusive and supportive training environments, or submit an application to our open track.

Fellows receive:

  • Competitive stipend ($60,000), health benefits, and discretionary training funds for a maximum of three years, upon annual review
  • Cohort-based professional development and community-building activities
  • Access to cutting-edge facilities at the new Wu Tsai Institute

Eligibility:

  • PhD degree or equivalent, awarded within past three years
  • Track record of discoveries and demonstrated level of scientific independence appropriate for a beginning postdoc
  • Self-identifying as being a member of a group underrepresented science. and/or demonstrated commitment to fostering diversity, equity, and inclusion.
  • Interdisciplinary orientation
  • International applicants welcome
  • Current Yale postdocs and PhD students are not eligible to apply

Deadline for applications is August 15.

To apply and for more info see: https://bit.ly/WTIPostdocFellows

Priority areas include:

  • Uncovering the molecular basis of neuroticism, a fundamental personality trait - Explore the effect neuroticism-associated DNA variants on gene expression and develop massively parallel reporter assays to test effects on neural systems. Applicants should have expertise in stem cell biology, neuroscience, massively parallel reporter assays, high-throughput CRISPR genomic manipulations, and/or statistical genetics and epigenetics, and be interested in bridging computational and experimental approaches.
  • Learning the language of thought: machine learning to infer spatiotemporal rules of cognition from mesoscopic calcium imaging data – Infer patterns in brain activity by applying natural language processing to large-scale calcium imaging datasets from awake behaving mice. A background in computer science, applied math, computational biology, machine learning, and experience working with large datasets is preferred. A strong interest (but not necessarily experience) in neuroscience is required.
  • Toward the neural bases of cooperative social interactions through a unique primate model - Unravel the prefrontal mechanisms underlying cooperation using a unique freely behaving marmoset model. Candidates should have experience in at least two of the following areas: non-human primate behavior, electrophysiology, or computational analysis.
  • The functional genomics of human cognition: from molecular and cellular processes though large-scale brain networks - Explore how genetic variation results in cognitive and behavioral differences by developing processes to link data across genetics, genomics, neuroimaging, and behavioral domains. Applicants should have demonstrated expertise in clinical, cognitive, translational, or network neuroscience, computational biology, or genetics.
  • Open Area – If you are an early-career researcher interested in foundational studies of the mind, but do not fit the priority areas above, we still welcome your application. We are particularly interested in candidates from underrepresented backgrounds with expertise in molecular and cellular neuroscience, systems and cognitive neuroscience, computational neuroscience, psychology, data science, artificial intelligence, biomedical engineering, brain-machine interfaces, and neuroethology. Applications in this track will be considered depending on mentor and funding availability.
Postdoctoral position in Inflammatory Skin Disease (Damsky lab)
Posting Date: June 18, 2021

The Damsky lab in the Department of Dermatology is seeking a postdoctoral associate. Broadly, our group studies the immunology of inflammatory skin diseases and novel treatment approaches. More specifically, our interests include:

  • Understanding basic mechanisms of inflammation in the skin
  • Evaluating novel therapies in clinical trials with translational immunologic components that teach us how a targeted intervention alters the underlying immune response
  • Current disease areas include atopic dermatitis, psoriasis, sarcoidosis, alopecia areata, other inflammatory alopecias, granuloma annulare, and others.
  • We also have active projects to evaluate novel molecular diagnostics to inform personalized disease selection in these areas
  • We are also developing new murine models of skin inflammation

Depending on the applicant’s specific interests there would be an opportunity to take a leading role in multiple areas.

Qualifications

  • PhD in relevant fields such as immunobiology, cellular biology, or molecular biology
  • Experience in cell culture, flow cytometry, and other cellular methods
  • Experience with basic molecular techniques, experience with RNAseq, scRNAseq, ATAC-seq a plus but not required
  • Experience with immunofluorescence staining of tissue and fluorescence microscopy a plus but not required
  • Experience with data analysis in R a big plus, if not, a willingness to learn
  • Experience working with mice a plus but not required

Interested candidates should email a CV to:

william.damsky@yale.edu

We are looking to hire immediately and will review applications as they are received, continuing until the position is filled.

Postdoctoral position in the Department of Dermatology(Myung Lab)
Posting Date: June 18, 2021

Peggy Myung, MD, PhD, is seeking a highly motivated post-doctoral research fellow (Ph.D., M.D., or M.D./Ph.D.) for a position in her laboratory in the Department of Dermatology, Yale School of Medicine. In the Myung lab, we study how programs of hair follicle development work at the interface of regeneration and skin tumorigenesis (Developmental Cell, 2019; Cell, 2016). In particular, our lab aims to dissect the molecular and cellular mechanisms that govern embryonic hair follicle development to gain insight into how these same mechanisms are reutilized during adult hair follicle regeneration and or dysregulated in basal cell carcinoma, the most common human skin cancer. As a post-doctoral fellow in our lab, you will have the opportunity to work within a team to perform basic science research that explores the cellular and molecular dynamics that controls these processes, using novel in vivo and genomic approaches. The projects employ a broad range of techniques, including mouse genetics, multi-photon live imaging, quantitative RNA fluorescent in situ hybridization, and single-cell RNA/ATAC sequencing.  Prior research experience using these techniques is a plus but not required. The candidate will also have opportunities to present his/her data at weekly lab meetings and at intramural and national/international conferences. The overall goal is to construct and perform scientific experiments that can be shared with the scientific community at large through peer-reviewed publications and speaking opportunities. In addition, the candidate will be given career development opportunities (e.g. grant-writing and public speaking skills) that are individually tailored to his/her long-term career goals. The ultimate goal is to create an experience that is rewarding and engaging for everyone in the lab and that fosters scientific and professional growth!

The candidate will be expected to perform the following:

  1. Assist with mouse colony management, husbandry and genotyping
  2. RNA in situ hybridization and immunohistochemical stains of mouse or human tissue followed by visualization using various microscopy techniques including multiphoton microscopy, confocal microscopy, and basic immunofluorescence/brightfield microscopy
  3. Basic molecular biology techniques such as quantitative PCR, subcloning, and preparation of RNA for bulk and single-cell RNA sequencing
  4. Preparation of single-cell suspensions from mouse skin for flow cytometry and FACS sorting
  5. Basic tissue culture techniques using primary skin cells and cell lines
  6. Embryonic and adult skin dissections
  7. Intraperitoneal and gavage administration of soluble compounds (e.g. tamoxifen) to mice
  8. Use basic software/statistical tools to analyze genomic data, including R packages for single-cell RNA sequence analysis
  9. Assist with data analysis, interpretation, and generation of figure quality data for publication and/or presentations
  10. Attend intra-mural and extra-mural conferences where he/she can present research data and build professional relationships
  11. Review and present relevant literature at journal clubs or lab meetings
  12. Attend weekly dermatology and/or pathology research in progress conferences as well as weekly lab meetings
  13. Attend one-on-one meetings with the PI to review scientific data/progress and goals and to provide reciprocal constructive feedback
  14. Prepare manuscripts of his/her primary research for publication
  15. Assist with lab organization

Interested candidates should email a cover letter that briefly describes their personal and career goals as well as their research/scientific background, their CV, and at least 3 letters of reference to peggy.myung@yale.edu

Postdoctoral position in the Center of Molecular and Cellular Oncology (Müschen Lab)
Posting Date: June 18, 2021

Our group is interested in comparative analyses of normal lymphocyte development and malignant transformation towards leukemia. We cover research areas with relevance to Immunology, Hematology and Cancer Biology. Our research involves experiments with primary human leukemia cells, normal lymphocyte development in humanized mice, leukemia and stem cell transplantation models, mouse genetics, gene editing, genetic biosensors of signal transduction, optogenetics, classical molecular and cell biology, a strong emphasis on mechanistic studies in oncogenic signal transduction. We strive to promote a culture of diversity and inclusivity for all its members, focusing on career development and innovative approaches to science.

Qualifications: PhD in cell or molecular biology, enthusiasm for science, willingness to think beyond established concepts and to try and learn new experimental and analytical tools. The lab takes a team science approach, being collaborative is important as well.

Your application should include in one single PDF:

CV, brief motivation statement, coordinates of three scientific mentors (references)

Methods/Techniques: Flow cytometry, mass spectrometry/quantitative phosphoprofiling, genetic biosensors of signal transduction, optogenetics, mouse genetics, bone marrow transplantation assays, retroviral gene delivery, whole exome sequencing and RNA-seq-analysis of clonal evolution of leukemia, pre-clinical drug testing in xenotransplantation models.

Recent work of the laboratory: To prevent the production of harmful autoantibodies and autoimmune disease, autoreactive B-cells and pre-malignant clones are eliminated by a process termed negative selection. Despite strict and rigorous negative selection, B-cells frequently give rise to autoimmune diseases and B-cell malignancies such as leukemia and lymphoma. Since humans can live without B-cells for extended periods of time, the Müschen laboratory systematically investigated lineage-specific vulnerabilities that are common in B-cell leukemia/lymphoma but not any other cell type. Contrary to the established dogma, these mechanisms are not only active in preventing autoimmune disease but also represent a novel class of therapeutic oncogenic targets in malignant B-cell tumors. Over the past five years, the Müschen Laboratory established innovative conceptual frameworks for the understanding of B-cell signaling mechanisms and negative selection, some of which are summarized below:

·      We discovered regulation of energy-abundance as the central determinant of negative B-cell selection: Hyperactivation of kinases downstream of an autoreactive B-cell receptor induces ATP-depletion and energy stress (Chen Nature 2015, Shojaee Nature Med 2016, Chan Nature 2017; Pan PNAS 2020).

·      Studying changes of energy-metabolism during B-cell transformation, we discovered that glucose carbon-flux was diverted in a way that left transformed B-cells uniquely vulnerable to inhibition of PP2A, an enzyme that coordinates glycolytic flux with antioxidant protection (Xiao Cell 2018).

·      We discovered that changes in cell-size are orchestrated by BCL6 and MYC. Opposed by MYC, BCL6 decreases cell-size by transcriptionally repressing glucose-uptake in favor of autophagy (Duy Nature 2012; Geng Cancer Cell 2015; Hurtz Genes & Dev 2019).

·      Tracking mechanisms of leukemia-initiation in 1,100 patients, we discovered pathway convergence as a novel therapeutic vulnerability in B-ALL. Only mutations that converged on one central pathway promoted leukemia progression. Genetic reactivation of divergent (suppressed) pathways engaged conflicting biochemical and transcriptional programs and subverted leukemia development. Pharmacological pathway reactivation to create a diverse signaling environment represents a novel strategy to prevent B-ALL relapse and drug-resistance (Chan Nature 2020).

·      Studying biophysical mechanisms of B-cell activation, we discovered that the short endosomal protein IFITM3 acts as a central scaffold for lipid-raft assembly and surface-expression of rafts-associated receptors. Membrane-recruitment of IFITM3 was essential for the initiation of PI3K-signaling, antibody affinity maturation and oncogenic B-cell transformation (Lee Nature 2020).

https://medicine.yale.edu/lab/muschen/

http://www.hhmi.org/scientists/markus-muschen

Postdoctoral position in cancer biology and therapy (Glazer lab)
Posting Date: June 17, 2021

A postdoctoral position is available immediately to study a novel tumor-targeting antibody for cancer therapy. Research in the lab is focused on developing novel approaches to cancer therapy by exploiting synthetic lethal vulnerabilities and leveraging tumor targeting strategies and fundamental mechanistic studies of cancer biology. Recent publications include Sulkowski Nature 2020 (PMID: 32494005) and Kaplan Science Translational Medicine 2019 (PMID: 31092693).

We offer a dynamic and stimulating work environment for conducting cutting-edge research and for facilitating career development. Interested candidates should have a strong research track record. While prior experience in cancer biology, molecular biology, and mouse tumor models is advantageous, we welcome researchers from all biomedical research backgrounds.

Qualified candidates should send their CV and contact information for at least two references to Peter Glazer, Departments of Therapeutic Radiology and Genetics, Yale School of Medicine at: peter.glazer@yale.edu

 

 

Postdoctoral position in Cardiovascular Research (Mani Lab)
Posting Date: June 17, 2021

A NIH funded postdoctoral position is immediately available in the laboratory of Dr. Arya Mani at the Cardiovascular Research Center at Yale University. The exciting project involves in vivo and in vitro molecular- and cellular-based studies to examine the role of Cela2a, a disease gene identified in the lab for atherosclerosis, diabetes and hyperlipidemia (Nature Genetics 2019) in glucose and lipid homeostasis in a mouse model of the disease.

Basic knowledge of molecular biology, cloning, expression analyses in cultured mammalian cells, protein purification, analysis of protein-protein interaction, FACS analysis, small animal handling is necessary. The applicants are closely mentored with the expectation that they work at the bench independently, interpret data, and contribute to the troubleshooting of their experiments. Excellent communication and interpersonal skills are a requirement for this position. Salary based on research experience.

Please submit a single PDF file containing a brief cover letter, CV, research experience and publications and information for 3 references to arya.mani@yale.edu

Postdoctoral position in nuclear phase separation and protein homeostasis (Schlieker Lab)
Posting Date: June 16, 2021

The Schlieker laboratory (https://medicine.yale.edu/lab/schlieker/) is seeking highly motivated researchers to join our collaborative and interdisciplinary team at Yale. Help us to characterize the role of nuclear envelope dynamics and nuclear protein homeostasis in relation to human disease. We also want to build the next generation of global scientific leaders, offering our scientists the mentoring, resources, and creative environment to launch successful careers.

We apply a broad range of interdisciplinary approaches including CRISPR-based genome wide screens, advanced life cell imaging, biochemical reconstitution and structural approaches. With these techniques, we investigate functional genetic networks operating within the nuclear envelope, monitor membrane dynamics both in vivo and in vitro, and mechanistically dissect molecular machines that sculp and remodel nuclear membranes. Ultimately, we want to understand how defects in these processes are tied to human pathology, informing corrective therapy.

Projects are available in these areas: (i) identifying the molecular function of Torsins (essential AAA+ ATPases) in the context of nuclear pore complex assembly (https://doi.org/10.1083/jcb.201910185); (ii) analyzing the function of chaperones in modulating phase separation and protein quality control in the nucleus. (iii) functional and molecular analysis of NOMO, a novel membrane-shaping protein (https://doi.org/10.1101/2021.01.28.428001).

Research environment: Being affiliated with two departments (Department of Molecular Biophysics and Biochemistry and Department of Cell Biology), we embrace collaborative approaches and provide a diverse and nurturing training environment. As a member of the Yale Nucleus Club, we hold regular joint lab meetings labs across three departments, offering exciting opportunities for intellectual exchange, collaborations and skill development in a vibrant scientific community. Postdocs will have access to an impressive variety of state-of-the-art core facilities as well as outstanding educational resources through the Yale Center for Teaching and Learning (https://poorvucenter.yale.edu/Postdocs).

Qualified candidates should have a PhD in biochemistry, cell biology or molecular biology and have strong communication and team skills.

If interested, please contact christian.schlieker@yale.edu with a copy of your resume.

Postdoctoral position in the Section of Pulmonary, Critical Care and Sleep Medicine (Llor Lab)
Posting Date: June 11, 2021

Yale School of Medicine, Section of Digestive Diseases is looking to hire a highly motivated Postdoctoral Associate to drive innovative translational research forward in the field of colorectal cancer. The post-doctoral associate will work under the supervision of Dr. Xavier Llor and Dr. Rosa Xicola on human oriented research projects aimed at understanding several colorectal cancer aspects including disparities, early age of onset, and hereditary forms. The projects encompass a range of aspects that include organoid harvesting and growth, molecular biology, and large data set curation and analysis. The individual will also manage the high-risk registry database. The post-doctoral associate should be able to work independently as well as in a team of translational researchers in the lab and along with other, postdocs, clinical staff, fellows and students. The major experimental tools that will be used include: tissue harvesting and organoid establishment, cell line growth, next-generation sequencing, and data set management and analysis.

Job Qualification:

1. A recent graduate or about to graduate with an MD, MD-PhD, or a PhD in the field of biology or similarly related fields.

2. Experience with translational work is preferred but not necessary.

3. Knowledge of major molecular biology techniques

3. Candidate should be willing to write independent funding applications after first few years of their post-doctoral position with the goal for a career as independent investigator.

The individual will be expected to make a significant contribution to the educational and research missions of the section. There will be opportunities to work on projects autonomously while working collaboratively with faculty, staff, post docs, and students. Supervision of other research personnel and other related duties will be expected. It is an excellent opportunity to learn about biomarker work in the context of clinical medicine and interventional trials.

Review of applications will begin immediately and will continue until the position is filled.  To apply, please submit a cover letter in the body of an email and CV/references as attachments to stacy.giangrande@yale.edu

Postdoctoral position in Chemical Biology Tools to Target Melanoma
Posting Date: June 11, 2021

A postdoctoral position is available immediately to apply the tools of chemical biology to characterize and target novel melanoma driver proteins. Techniques include peptide selection and preparation, chemoproteomics, and cell-based assays. Successful candidates will have a Ph.D. or equivalent with strong preparation in protein or peptide biochemistry, recombinant DNA technology, and cell and molecular biology. Chemical biology experience is preferred. We particularly welcome candidates from backgrounds underrepresented in science to apply.

The position is supported by funding from the Melanoma Research Alliance and the YCC Meyers Award Funds . The candidate will be part of a vibrant collaboration between the research groups of Dr. Ruth Halaban, Yale University Department of Dermatology, and Dr. Sarah Slavoff, Yale University Department of Chemistry. For representative recent publications, see PMID: 33357462, PMID: 33479206, PMID: 31040916, and bioRxiv preprint doi: https://doi.org/10.1101/2021.04.20.440286.

Interested candidates are encouraged to send a CV, description of research interests, and three letters of reference to:

Sarah Slavoff, Ph.D.

Department of Chemistry
Institute of Biomolecular Design and Discovery

Yale University

West Haven, CT 06511

Email: sarah.slavoff@yale.edu

Yale-Boehringer Ingelheim Biomedical Data Science Postdoctoral Fellowship Program 2021-2024
Posting Date: June 4,2021

Yale University and Boehringer Ingelheim are seeking applications for Postdoctoral Researchers for a newly launched Biomedical Data Science Fellowship, which is a three-year full-time program. Applicants with strong biomedical data science background and research experience are invited to submit research proposals for consideration. If approved for a fellowship, they will be jointly mentored throughout the research process by Yale’s faculty and scientists from Boehringer Ingelheim. Fellows will not only have access to Yale’s robust computational resources, biomedical data repositories and faculty expertise, but also benefit from access to Boehringer Ingelheim’s corporate labs, scientists and executives. In addition to receiving research funding and mentorship, program fellows will be invited to participate in campus and corporate visits, networking events, and annual symposia.

A joint selection committee comprising representatives of Yale and Boehringer Ingelheim will set annual data-driven research themes for the program. These themes may include such topics as genomic analysis, biomarkers, data-driven therapeutic research, medical image informatics, precision medicine, and translational medicine. The selection committee will consider proposed research projects’ alignment with prioritized themes in judging submissions and post-doctoral applicants.

The ideal candidate will have earned a PhD degree in the area of, computational biology, bioinformatics, data science, or relevant scientific disciplines, as well as excellent computing skills.

They will have demonstrated analytical and communication skills, including the ability to effectively describe scientific material to both specialized and lay audiences, and strong CVs, preferably having published in high-impact journals and presented at international meetings.

Applicants should submit current CV, short summary of past accomplishments, project proposal that includes a detailed research plan, summary of how the submitted project proposal aligns with the Theme, and a statement of how the Program aligns with your educational and career goals. All information from the applicant should be submitted electronically through https://medicine.yale.edu/cbds/bdsfellowship/application/

The program will be based at the Center for Biomedical Data Science (CBDS) in New Haven, Connecticut. The center is an essential part of a growing data science hub at Yale University, which has identified integrated data science as one of its primary investment areas over the next decade. CBDS is located within Yale School of Medicine and currently supports faculty members and researchers representing such disciplines as bioinformatics, modeling, statistics, computer science, artificial intelligence, mathematics, biology, precision medicine, and public health.

Compensation is competitive and includes health insurance and other benefits afforded to postdoctoral associates at Yale.

Submission deadline: June 21, 2021 12:00am (ET) Review of applications will begin immediately.

Notification to applicants: July 19, 2021

Program start date: September 1, 2021

For more information see https://medicine.yale.edu/cbds/bdsfellowship/            

For questions concerning this search, please contact cbds@yale.edu

Postdoctoral position in Machine Leaning for Brain Image Analysis (Payabvash Lab)
Posting Date: June 4, 2021

The Department of Radiology and Biomedical Imaging at Yale University is seeking highly motivated postdoctoral associate to join our team at Payabvash Lab. The research focus is on application of deep-learning for automated assessment of brain CT and MRI scans in patients with stroke and brain injury. Our goal is to devise novel tools for diagnosis, outcome prediction, and risk-stratification of patients with cerebrovascular diseases, based on wealth of information extracted from medical images and clinical records.

Successful applicants will have the opportunity to work in close collaboration with Department of Biomedical Engineering, and Department of Neurology at Yale. We are working on a large cohort of multi-institutional multi-national datasets to address some of the most pressing needs in patients who are susceptible to brain injury. Postdocs are expected to develop and deploy deep neural networks for medical image analysis, utilizing the available datasets. The postdocs will also oversee and lead graduate students and RAs working in the lab.

Preferred qualifications include:

  • PhD in computer science, electrical engineering, or biomedical engineering
  • Experience with application of CNN for image classification and segmentation – preferably medical images
  • Advanced programming experience and analytical skills
  • A record of publication and/or conference presentations

Qualified candidates should submit a cover letter describing previous programming experience, CV, and three references to: The Department of Radiology and Biomedical Imaging at Yale University is seeking highly motivated postdoctoral associate to join our team at Payabvash Lab. The research focus is on application of deep-learning for automated assessment of brain CT and MRI scans in patients with stroke and brain injury. Our goal is to devise novel tools for diagnosis, outcome prediction, and risk-stratification of patients with cerebrovascular diseases, based on wealth of information extracted from medical images and clinical records.

Successful applicants will have the opportunity to work in close collaboration with Department of Biomedical Engineering, and Department of Neurology at Yale. We are working on a large cohort of multi-institutional multi-national datasets to address some of the most pressing needs in patients who are susceptible to brain injury. Postdocs are expected to develop and deploy deep neural networks for medical image analysis, utilizing the available datasets. The postdocs will also oversee and lead graduate students and RAs working in the lab.

Preferred qualifications include:

  • PhD in computer science, electrical engineering, or biomedical engineering
  • Experience with application of CNN for image classification and segmentation – preferably medical images
  • Advanced programming experience and analytical skills
  • A record of publication and/or conference presentations

Qualified candidates should submit a cover letter describing previous programming experience, CV, and three references to: Payabvash_lab@yale.edu

Postdoctoral position, Bereavement Project, Child Study Center
Posting Date: May 31, 2021

The Yale Child Study Center Bereavement Project is seeking a Postdoctoral Associate to support a grant funded program which provides training and resources for healthcare professionals on topics related to child and family bereavement. The postdoctoral associate’s primary responsibilities will include (1) adapting training materials and developing curricula for various healthcare audiences on topics including (but not limited to) grief theory, child grief, parental grief, perinatal grief, traumatic grief, and how this impacts healthcare professionals, (2) delivering virtual and in-person trainings to nursing students, medical students, residents, fellows, and faculty (3) tracking and evaluating trainings delivered, (4) researching national climate of grief training in medical settings and applying these findings to further adaptations of the curriculum. Under the leadership of Dr. Amanda Lowell (project director) and Dr. Linda Mayes (PI and director of the Yale Child Study Center), the postdoctoral associate will also have a unique opportunity to select and engage in additional research and/or clinical opportunities of interest.

Qualified candidates are those who have recently completed a PhD in psychology, social work, psychiatric nursing, or related field. Competitive applicants will have demonstrated experience in program development, particularly in university health systems. Preference will be given to candidates with prior experience providing trainings, and those with interest in pediatrics and/or grief. Applicants must have strong interpersonal and public speaking skill, as well as the ability to work both independently and collaboratively. Applicants must be citizens or permanent residents of the United States. Applicants need not be licensed in a clinical discipline, as some opportunity for supervised clinical experience will be available if desired.

The position may start remotely in accordance with Yale University guidance around COVID-19 until the university resumes regular on campus operations, which is planned for August 1, 2021 and as determined by the business needs of the department.Review of applications will begin immediately and continue until the position is filled.

In accordance with university requirements for a safe return to in-person university operations, all faculty, staff, and postdoctoral and postgraduate trainees will be required to be fully vaccinated against COVID-19 by August 1. For additional information, please visit  https://your.yale.edu/work-yale/workplace-guidance/workplace-guidance-faqs

To apply, please send a single PDF documenting the following to amanda.lowell@yale.edu

1. Cover letter

2. Curriculum vitae

3. Names and contact information of three academic or clinical references familiar with the applicant’s skills and experience (reference letters are not needed at this time)

Postdoctoral position -Mindfulness, Social Connectedness, and Psychological Well-Being Project Team
Posting Date: May 31, 2021

The Yale Center for Emotional Intelligence, part of the Child Study Center at the Yale University School of Medicine, conducts research and teaches people of all ages how to develop their emotional intelligence. Our work focuses on: (1) the development and impact of social and emotional skills among diverse populations, including education settings and organizations, and (2) the mechanisms by which social and emotional skills and training impact significant life outcomes.

We are looking for a Postdoctoral Associate to join our Mindfulness, Social Connectedness, and Psychological Well-Being Project Team. Our team is launching a randomized controlled trial (RCT) in the Fall of 2021 investigating the effects of Compassion Cultivation Training (CCT), Mindfulness-Based Stress Reduction (MBSR), and control group training on college student social connectedness/loneliness, and psychological health and well-being. We are implementing a biopsychosocial, multiple-levels-of-analysis approach that will index college student subjective experiences, social behavior, and biological functioning (e.g, cortisol and interleukin-6). The project goals are to test the efficacy of prosocially-oriented contemplative interventions (CCT) as compared to the more well-studied mindfulness-based interventions (MBSR) in promoting healthy, connected, and meaningful social lives for college students and beyond. We are also interested in understanding for whom the trainings are most effective (demographic moderators, including gender and racial/ethnicity identity) and why (biopsychosocial mediators of intervention effects). The results of this project will inform larger efforts to foster social health and psychological well-being in college students and other chronically stressed populations, including educators and medical professionals.

The postdoctoral associate will be responsible for contributing to: study design; data collection and cleaning; quantitative, qualitative, and mixed methods data analyses, including using machine learning and AI text-based analytic techniques; programing and troubleshooting online study projects on Qualtrics; liaising with participants and intervention trainers inside and outside of Yale University; preparing academic conference proposals; and attending routine meetings at the Yale Center for Emotional Intelligence with Yale staff and our collaborators, and other related tasks as needed. Dr. James Floman will oversee day-to-day work assignments and be the primary supervisor. The Director of Research, Dr. Christina Cipriano, will provide additional supervision and professional support.

Skills and Qualificiations

·         Qualified candidates will have recently completed a PhD in psychology or affective science

·         Specialization in mindfulness, meditation, and contemplative science, affective science and well-being, and/or compassion and prosociality/positive psychology interventions

·         Proficiency in SPSS, Mplus, R, and/or Python

·         Advanced data analysis including experience with structural equation modeling, growth curve modeling, multi-level modeling, and/or experience sampling methods

·         Experience with randomized control trials in psychological or cognitive science

·         Experience with research using biological markers such as cortisol and interleukin-6

·         Machine learning/AI approaches to analyzing open-ended text

·         Excellent time management skills, including comfort working under deadlines

·         Superior written and oral communication skills

·         Ability to work both independently and collaboratively

The anticipated start date is July 2021. The position may start remotely in accordance with Yale University guidance around COVID-19 until the university resumes regular on-campus operations, which is planned for August 1, 2021 and as determined by the business needs of the department.

In accordance with university requirements for a safe return to in-person university operations, all faculty, staff, and postdoctoral and postgraduate trainees will be required to be fully vaccinated against COVID-19 by August 1. For additional information, please visit https://your.yale.edu/work-yale/workplace-guidance/workplace-guidance-faqs.

To Apply

Please send a cover letter and CV to Dr. Annette Ponnock at annette.ponnock@yale.edu. Review of applications will begin immediately and continue until the position is filled. Please have contact information for three references and an academic writing sample available upon request.

ABOUT THE YALE CENTER FOR EMOTIONAL INTELLIGENCE

Emotions drive learning, decision-making, creativity, relationships, and health. The Yale Center for Emotional Intelligence uses the power of emotions to create a more effective and compassionate society. Helping children and adults develop emotional 

Postdoctoral position in Cardiology (Sinusas lab)
Posting Date: May 25, 2021

Work will be under the general direction of Drs. Sinusas and Thorn and will include management of research studies and associated activities in the Yale Translational Research Imaging Center (Y-TRIC). They will actively participate in research design, implementation, and daily operation of the lab related to selected research projects primarily funded by NIH grants.

Essential Duties:

·       Actively participate in research planning and scheduling.

·       Perform literature searches to optimize study protocol and experiments to meet study objectives and aims.

·       Recommend the design and implementation of multifaceted independent research projects related to currently funded projects of Dr. Sinusas.

·       Carry out independent research projects under the guidance of Drs. Sinusas and Thorn with technical support of laboratory staff.

·       Working independently under the general supervision of the Principal Investigator, perform small and large animal experiments that employ novel multimodality imaging techniques including, single photon emission computed tomography (SPECT), computed tomography (CT), echocardiography, x-ray fluoroscopy.

·       Collect, organize, and analyze data for presentation and publication.

·       Prepare reports, tables, and figures and accurately present compiled findings to PI for use in manuscripts and grant applications.

·       Presenting results at local and national meetings.

·       Supervise and train other post-doctoral fellows on techniques, use of equipment, and new experimental techniques.

·       Maintain safety records to comply with Yale policies and procedures regarding use of radiation and biohazards.

·       Prepare documents related to IACUC and IRB submission.

Experience and Training:

Doctoral degree in medicine, veterinary medicine or PhD in biological sciences or engineering.

Skills and Abilities:

·       Preference for experience in imaging and/or image processing.

·       Preference for experience with research on large animals and animal handling (particularly swine).

·       Preference for some surgical experience and post-operative care.

·       Preference for knowledge and or exposure in cardiovascular and/or pulmonary medicine and research.

·       Comfortable with the use of radiotracer and x-ray generating equipment.

Send a CV to Dr. Sinusas at albert.sinusas@yale.edu.

'Postdoctoral position in Vascular Biology investigating the mechanisms that control arterial disorders (Guzman Lab)
Posting Date: May 19, 2021

Postdoctoral positions are available in the Laboratory of Dr. Raul J Guzman, Chief, Division of Vascular and Endovascular Surgery at Yale University School of Medicine.

The research program focuses on investigating the mechanisms that control arterial disorders including calcification and restenosis. The laboratory uses multiple approaches including gene knockdown, overexpression, and deficiency in cell culture, ex vivo organ culture, small animal models, and transgenic mice. Its goal is to identify novel mechanisms that control pathologic arterial responses and to develop therapeutic agents to prevent them.

Qualified applicants are those who have earned a Ph.D. or equivalent degree with a strong background in vascular biology or related fields. The candidates should have prior experience with cell and molecular biology and small animal techniques. Ideal candidates will have the ability to independently design, execute and troubleshoot experiments. They will have the ability to collect, analyze and interpret data in preparation for manuscript publication. They will also possess the ability to communicate in English both verbally and in writing to present experimental findings at internal meetings and scientific conferences.

To apply for this position please submit your CV, a cover letter, and contact details of three references to yujun.cai@yale.edu 

Postdoctoral position in epigenetic dysregulation mechanisms in gastrointestinal cancers
Posting Date: May 11, 2021

A Postdoctoral Fellowship position is available in the laboratory of Dr. Nita Ahuja at the Department of Surgery, Yale School of Medicine. The research in the Ahuja laboratory is focused on understanding the epigenetic dysregulation in various cancers during disease progression using patient samples, patient derived organoids, PDX mouse and various cell line models, as well as translating the findings to develop novel detection biomarkers and identify novel treatment targets.

We are looking for motivated individuals interested in studying the molecular, cellular, and epigenetic dysregulation of gastrointestinal cancers and other disorders. Applicants should have a PhD or MD/PhD in biological sciences, molecular/cell biology, genetics or related fields. The candidate should be self-motivated and have a proven track record of productivity. The candidate should possess excellent written and verbal communication skills, as well as ability to work collaboratively.

Qualified applicants should email the application package (statement of interest, CV, and contact information for three referees) as a single pdf document. To apply or any other questions regarding the position please directly contact Anup Sharma (anup.sharma@yale.edu) for consideration.

Postdoctoral position in Infectious Diseases (Omer Lab)
Posting Date: May 4, 2021

A postdoctoral fellow is sought for a research position in an interdisciplinary vaccine research group. Fellow should have strong quantitative skills and a doctoral degree in epidemiology, global health, economics/econometrics, or another relevant quantitative discipline. PhD in lab sciences with experience in field or clinical work will be considered. Individual with the potential for leadership, a desire to cross interdisciplinary boundaries, and aptitude for developing an independent research portfolio will be strong applicants. Researcher in their first or second postgraduate research year is preferred, but third-year researcher will also be considered.

Examples of duties:

  • Coordination of research efforts between different research sites, nationally and internationally
  • Drafting grant proposals and protocols
  • Primary and/or secondary authorship of original research manuscripts
  • Mentoring of predoctoral researchers

Minimum qualifications:

  • Doctoral degree in epidemiology, global health, economics/econometrics, or another relevant quantitative discipline
  • Strong quantitative skills with data cleaning and analysis as well as manuscript drafting and publication
  • High EQ and a strong focus on team-oriented research

Omer Research Group

Omer Research Group is involved with a diverse complement of vaccine research, ranging from field and clinical trials to epidemiological studies and studies on vaccine acceptance and policy. The group also maintains collaborative research relationships with vaccine immunology groups. The group is headed by Saad B. Omer, MBBS, MPH, PhD.

Research Group Environment and Philosophy

Omer Research Group works both domestically and internationally; the postdoctoral positions will focus on a variety of interdisciplinary projects having to do with vaccine research. This group also has an orientation towards strong mentoring and focuses on developing skills as well as the ability to lead an independent research program. We invest in mentee growth and have a culture of mutual support. The group fosters a rigorous scientific research environment but is cognizant of the importance of work-life balance - and works with members to strike a healthy balance between research and personal life.

Interested applicants should send their CV to omer.admin@yale.edu

Postdoctoral position in biliary cell biology (Gupta Lab)
Posting Date: May 4, 2021

The Gupta Lab, located in the Yale Liver Center is seeking a motivated and dedicated Postdoctoral Associate to join its research program. The lab is focused upon harnessing murine genetics, using human tissue samples, and utilizing single-cell and bulk RNA sequencing technologies to understand cellular crosstalk between biliary epithelial cells and surrounding mesenchymal cells during homeostasis and disease. The major goal of the lab is to dissect how these cell types are perturbed in the disease state to gain greater understanding of human biliary disease.

Postdoctoral training in the lab includes molecular biology, flow cytometry, mouse genetics and surgery, biliary cell isolation, next generation sequencing, confocal/multiphoton imaging, and more. Additionally, candidate will be mentored in research presentation, manuscript preparation, and is further tailored depending on the candidate’s career goals.

Applicants should have an MD, PhD, or MD/PhD with a background in cell and molecular biology, genetics, genomics and/or other related biological fields.

If you are interested in this position, please send (1) your CV, (2) a cover letter with research interests and career goals, and (3) a list of three references for contact to vikas.gupta@yale.edu. Applications will be reviewed on a rolling basis until the position is filled.

Postdoctoral position in tissue engineering models of kidney disease
Posting Date: April 30, 2021

Yale School of Medicine is seeking a highly motivated Postdoctoral Associate to join a collaborative effort between the laboratories of Laura Niklason MD, PhD (Adjunct Professor in the Departments of Anesthesia and Biomedical Engineering) and William Chang MD, PhD (Assistant Professor in the Department of Medicine and Section of Nephrology). The research project will focus on tissue engineering models of kidney disease. More specifically, the Associate will develop microfluidic devices to model and analyze tubular dysfunction in polycystic kidney disease. The Associate will be supervised by Drs. Niklason and Chang. We are seeking an enthusiastic and motivated scientist who will receive intensive mentorship and training in laboratory research techniques, critical thinking, and problem solving. The Associate will participate in manuscript publications, laboratory group meetings, and will gain critical experience presenting their research.  

Applicants for the position should have an MD, PhD, or equivalent with significant experience in biomaterials, biomedical engineering, or a related field. Experience in bioinformatics would be beneficial.

Application materials consisting of a cover letter and Curriculum Vitae should be submitted electronically to Dr. Chang (w.chang@yale.edu). The cover letter should include research interests, career goals, and contact information for three potential references. Review of applications will begin immediately and will continue until the position is filled.

Postdoctoral Fellowship in International Development at Yale, 2021-22
Posting Date: April 22, 2021

The Jackson Institute for Global Affairs and the  Economic Growth Center  (EGC) at Yale are seeking applications for a Postdoctoral Associate in international development for the 2021-22 academic year.

The Postdoctoral Fellow will conduct independent research and collaborate with Jackson Institute and EGC faculty, contributing to the intellectual life within and between the centers.  In the spring semester, the Fellow will be expected to teach Approaches to International Development, a core course for undergraduate students in Yale’s Global Affairs major.  The successful candidate will also be involved in multiple EGC data-oriented initiatives. This includes advising on the development of training materials for economics graduate students on Stata and potentially other programming packages.  In addition, the fellow will have the opportunity to collaborate with a set of EGC faculty on an initiative pushing forward data access and archiving as a public good for development research.

The ideal candidate will have a demonstrated ability in conducting high quality, policy-relevant research on topics in international development and economics. This is a full-time position.  Fellows will be expected to be in full-time residence at Yale for the duration of their appointment.

Applicants should submit a cover letter, CV, one page description of research plans, a writing sample, teaching statement with evidence of teaching excellence, and three letters of recommendation. All information from the applicant should be submitted electronically through Interfolio at  http://apply.interfolio.com/86754  .

Compensation is competitive and includes health insurance and other benefits afforded to postdoctoral associates at Yale. For more information see https://your.yale.edu/enroll#pda .

Review of applications will begin immediately and will continue until the position is filled. For questions concerning this search, please Larisa Satara at larisa.satara@yale.edu.

Postdoctoral position in Human Systems Immunology (Konnikova Lab)
Posting Date: April 21, 2021

Research in the Konnikova group is directed at studying the development and maintenance of mucosal immunity at barrier sites such as the intestine and placenta. We are interested in understanding how homeostasis is established and maintained in humans and what goes awry to cause disease such as necrotizing enterocolitis and inflammatory bowel disease in relationship to intestinal health and preterm labor in case of placental biology. We are seeking a motivated and dynamic postdoctoral candidate to join our team who is interested in applying cutting edge techniques including mass cytometry and single cell RNA sequencing in combination with cell biology and organoid approaches to studying development of human mucosal immunity at barrier sites. My group has access to the CyTOF and genomics cores at Yale as well as state-of-the-art cell and molecular imaging facilities. During this time, the successful applicant will obtain further training in translational research, in vivo model systems and a range of immunological techniques.

The candidate will be expected to have an MD, PhD, or MD/PhD with experience in immunology. Preference to candidates with involvement in human immunology will be given, but it is not a requirement. The successful candidate will be self-motivated and have the capacity for independent evaluation of the literature. Prior knowledge in primary cell isolation, flow cytometry, imaging techniques and single cell techniques would be an added benefit. For more information on our group, please visit our website – www.konnikovalab.com.

Interested applicants should send a brief statement of interest and curriculum vitae with contact information for three references to the Principal Investigator, Dr. Liza Konnikova – liza.konnikova@yale.edu.

Postdoctoral position in Regulatory RNAs in Cancer (Dimitrova Lab)
Posting Date: April 20, 2021

A postdoctoral position is available in the laboratory of Dr. Nadya Dimitrova, Assistant Professor in the Department of Molecular, Cellular and Developmental Biology at Yale University. Research in the Dimitrova laboratory focuses on investigating the roles of a novel class of genes, called long noncoding RNAs (lncRNAs) in cancer biology. To date, lncRNAs have remained largely uncharacterized but emerging evidence suggests an involvement in a broad range of biological processes and in human disease, including cancer. We select candidates based on their regulation by key oncogenes and tumor suppressors or based on their involvement in cancer processes, such as the DNA damage response, oncogenic transformation, and metastasis.

Our goal is to understand how candidate lncRNAs contribute to oncogenic and tumor suppressive networks at the molecular, cellular, and organismal level and how deregulation of lncRNAs leads to cellular transformation and tumor development. At the molecular level, we aim to elucidate the diverse mechanisms by which cis- and trans-regulatory lncRNAs fine-tune oncogenic and tumor suppressive networks by modulating transcriptional and translational pathways.

At the cellular level, we aim to understand how lncRNAs participate in the decision-making processes in complex transcriptional networks and what are the consequences of lncRNA activity for cellular homeostasis and stress response. Finally, to bring insights into the vastly understudied contribution of lncRNAs to tumorigenesis in vivo, we are testing how inappropriate expression of regulatory lncRNAs influences tumor development in mouse models of lung and breast adenocarcinomas.

A successful candidate will hold a Ph.D. degree, will be highly motivated to perform cutting edge research and to interact with a dynamic, young group of investigators. Candidates from diverse scientific backgrounds are strongly encouraged to apply.

Additional information can be found at dimitrovalab.yale.edu

Candidates should send a CV, names of three references, and a cover letter with a brief statement of future research interests and career goals to: nadya.dimitrova@yale.edu

Postdoctoral position at the Zigler Center in Child Development & Social Policy
Posting Date: April 15, 2021
The Zigler Center in Child Development & Social Policy under the Yale Child Study Center brings together a diverse group of researchers and practitioners in an effort to improve the well-being of children and families by bringing objective child development research into the policy and public arenas.
 
We seek a postdoctoral associate (postdoc) who will be responsible for analyzing data across Zigler Center projects that include (1) a national survey of child care workers around COVID-related issues (one of the largest occupational epidemiology studies ever conducted), and (2) a statewide evaluation of early childhood mental health consultation. The postdoc will also lead and/or assist in data management and data collection of an RCT of early childhood mental health consultation implementing the Infant-Toddler CHILD. The postdoc will also support other tasks related to the team’s research, such as manuscript preparation, grant writing, and the design of future studies.
 
Skills and Qualifications
The successful candidate will have: (1) completed a doctoral degree in psychology, child development, psychometrics, data science, or a related field (ABD acceptable); (2) strong methodological, analytic, and writing skills; (3) specialization or demonstrated interest in the areas of preschool expulsion, equity, social justice, and anti-racism at interpersonal and systemic levels, early childhood mental health consultation, social and emotional learning; (4) the ability to balance attention to detail with a big-picture understanding of research endeavors; (5) an aptitude for and interest in data management and measurement; (6) strong interest in programs and policies aimed at improving the well-being of children and families; and (7) the ability to work both independently and collaboratively. Preference will be given to candidates with expertise in large-scale data management and complex statistical analyses, and mixed methods design. Experience/expertise in legislative and regulatory policy analyses is a plus! Bilingual applicants are highly encouraged to apply.
The postdoctoral position is a one-year appointment with renewal contingent upon satisfactory performance and availability of funding.
The anticipated start date is July 2021. The position may start remotely in accordance with Yale University guidance around COVID-19.
 
 
To Apply
Interested applicants should submit via e-mail a cover letter and CV, a first-authored writing sample, and a minimum of three (3) letters of reference (may be submitted separately, or combined with application package) to: itchild@yale.edu. Incomplete applications will not be reviewed. Please make “Zigler Center Postdoc Position” the subject line of your e-mail. Review of applications will begin immediately and continue until position is filled.
Postdoctoral position in the Department of Pathology (Kluger Lab)
Posting Date: April 13, 2021

Two postdoctoral positions in computational single-cell RNA sequencing and spatial transcriptomics & proteomics are available in the laboratory of Dr. Yuval Kluger at Yale University School of Medicine. The Kluger Lab is affiliated with the Applied Mathematics program in the Department of Mathematics, Computational Biology & Bioinformatics program, as well as the Yale Center for Biomedical Data Science and the Yale Cancer Center.

The group is focused on methodological development of novel computational methods including deep learning, graph theory, and spectral approaches to analyze high-throughput and high-dimensional biomedical data. Most of our current applications concentrate on analysis of data generated in single cell RNA sequencing and spatial transcriptomics/proteomics studies which provide unprecedented opportunities to conduct detailed analyses of cell subpopulations. Fulfilling the promise of these studies and biomarker discovery requires robust computational approaches to support detection of rare phenotypes and unanticipated cellular responses. Current approaches for denoising, calibration, clustering and visualizing of such data types suffer from challenges such as erroneous imputation of non-expressed genes, removal of multivariate batch effects, detection of local differences between cell distributions, and inefficiencies of clustering and dimensional reduction methods of very large datasets. We have developed novel and efficient spectral and neural network prototypes suitable for addressing these issues in high throughput data contexts and further develop and adapt these methods to data generated by our collaborators.

The group is actively engaged in multi-disciplinary national collaborations with large project teams including the SCORCH consortium and the HuBMAP, as well as multiple groups from the Departments of Pathology, Immunobiology, Neurology, Genetics, Internal Medicine and the Cancer Center. The successful candidate will utilize single cell transcriptomics, spatial transcriptomics as well as other genomic, epigenomic and proteomic data from our experimental collaborators and from the public domain and develop novel techniques to characterize a variety of biological systems. The focus will be on immunology, melanoma, and lung cancers studies and single cell characterization of several brain regions relevant to persistent HIV infection and opioid use disorder. The scope of the work could extend to other systems. The successful candidates must be able to work well with groups from different disciplines and to present scientific results in a clear and effective manner.

Research projects may involve, but not limited to:

  • Analysis of high throughput transcriptomics, proteomics, genomics data, such as single cell RNA sequencing data, spatial transcriptomics data in a collaborative setting.
  • Data management and pipeline development for consortiums.
  • Develop and implement new bioinformatics and computational biology algorithms

Qualifications:

  • Ph.D. in Computational Biology, Bioinformatics, Genetics, Computer Science, Applied Mathematics, Statistics, Physics, Engineering or other related fields.
  • Proficiency with the analysis of next generation sequencing data.
  • Ability to develop, implement and benchmark computational methods.
  • Solid programming skills.
  • Experience with Python and R programming languages is preferred.
  • Interest in collaborating with biologists and physician scientists.
  • Familiarity with UNIX and cluster computing is preferred.

Apply:

Qualified candidates who are interested in applying should e-mail an application package, including: statement of interest, CV, and contact information for references. Please send your application package to Dr. Yuval Kluger (yuval.kluger@yale.edu). In the subject line, write “your full name, postdoc application”.

Postdoctoral position in the Department of Therapeutic Radiology (Hayman Lab)
Posting Date: April 12, 2021

The Hayman Lab, led by Thomas Hayman, MD, PhD, in the Department of Therapeutic Radiology at Yale University is recruiting a highly motivated and creative postdoctoral fellow.  We are a cancer biology lab that is focused on utilizing genetic approaches to understand and exploit resistance mechanisms to DNA damage. 

Our research program has a particular interest in studying the interplay between the cell intrinsic immune machinery and DNA repair processes using in vitro cell models, genetic screens (such as CRISPR and RNA interference), and animal models.  We have a strong translational focus that is founded in a preclinical mechanistic understanding of basic biological processes with the ultimate goal of shaping these discoveries into therapeutic strategies for cancer patients.

We are seeking a candidate who will contribute to the discovery and translation of biological processes that modulate tumor responses to DNA damaging therapies (e.g. radiation) and immunotherapy.  Interested applicants should hold a PhD. or M.D. with considerable laboratory experience and a strong background in cancer biology, molecular biology, genetics, radiation biology or other related fields.  Prior experience with in vivo animal tumor models, CRISPR/Cas9, IF/IHC and DNA damage assays is highly desired, but not a requirement.  The candidate should be self-motivated and have a proven track record of productivity.  Excellent written and oral communication skills are expected. 

How to Apply:

Candidates should send a Curriculum Vitae, a cover letter detailing research interests and career goals, and contact information for three references to Dr. Thomas Hayman (thomas.hayman@yale.edu).

Postdoctoral position in the Dept of Cardiovascular Medicine
Posting Date: April 9, 2021

This is a Postdoctoral Research Position opening in the Dept of Cardiovascular Medicine at Yale University School of Medicine. All job duties will be performed in 10 Amistad St, New Haven, CT in a basic research laboratory which focuses on studying the role of complement using humanized disease models. The successful application will work closely with the principal investigator and with another research technician to develop projects which will form the basis for extramural funding applications.

Principal Responsibilities:
1) Perform cell culture using aseptic technique
2) Perform molecular cloning studies
3) Carry out mouse breeding and handling.
4) Communicate results and work-related issues to colleagues and supervisors

Required Education and Experience:
This position requires a PhD degree or equivalent. Prior research experience in cellular immunology and/or molecular cloning are preferred.

Candidates should email a cover letter, CV, and contact information for three references to dan.jane-wit@yale.edu

Postdoctoral position with the Adolescent Initiatives Team at the Yale Center for Emotional Intelligence
Posting Date: April 9, 2021

The Yale Center for Emotional Intelligence, part of the Child Study Center at the Yale University School of Medicine, conducts research and teaches people of all ages how to develop their emotional intelligence. Our work focuses on (1) the development and impact of social and emotional skills among diverse populations, including education settings and organizations, and (2) the mechanisms by which social and emotional skills and training impact significant life outcomes.

We are looking for a Postdoctoral Associate to join the Adolescent Initiatives Team (PIs: Drs. Jessica Hoffmann and Rachel Baumsteiger). This team works on a range of projects, including (1) the development of a web-based app designed to measure students’ perceptions of school climate; (2) the development of a tool designed to assess students’ momentary emotions and emotion regulation at school; and, (3) the development and testing of the RULER and inspirED: two complementary social emotional learning initiatives for middle and high schools.

The postdoctoral associate’s primary responsibility will be to analyze data across projects. They will also be expected to support in other tasks related to the team’s research, such as the preparation of research articles, grant writing, and the design of future studies. Jessica Hoffmann and Rachel Baumsteiger will oversee day-to-day work assignments and be the primary supervisors. The Director of Research, Dr. Christina Cipriano, will provide additional supervision and professional support.

Skills and Qualifications

• Qualified candidates will have recently completed a PhD in psychology, education, or a related field

• Specialization or demonstrated interest in the study of adolescent development, emotions, and psychological assessment

• Excellent statistics skills, including experience conducting multi-level modeling

• Ability to communicate effectively (e.g., writing research papers, giving presentations)

• Strong project management skills

• Ability to work both independently and collaboratively; an interest in mentorship is preferred

The anticipated start date is July 2021. The position may start remotely in accordance with Yale University guidance around COVID-19.

To Apply

Please send a cover letter and CV to jessica.hoffmann@yale.edu and rachel.baumsteiger@yale.edu. Within your cover letter, please describe your level of familiarity with multi-level modeling.

Reviews of applications will begin immediately and continue until position is filled. Please have three letters of reference available upon request.

ABOUT THE YALE CENTER FOR EMOTIONAL INTELLIGENCE

Emotions drive learning, decision making, creativity, relationships, and health. The Yale Center for Emotional Intelligence uses the power of emotions to create a more effective and compassionate society. Helping children and adults develop emotional intelligence is central to the mission of the Center. To date, schools have been at the center of these efforts. RULER, the Center’s signature program, draws on leading pedagogical practices as well as advances in psychology and neuroscience, and it has been honed through years of classroom observation, interviews, and the most demanding evaluations. Creating awareness—both of self and others—about emotions and developing the skills of emotional intelligence can improve children’s prospects in life and contribute, in turn, to healthier, more compassionate families, workplaces, and communities. RULER does this by teaching adults and children the skills of emotional intelligence. Since 2005, more than 600 schools have implemented RULER, affecting the lives of over 500,000 students. Accordingly, we integrate emotional intelligence skill building, the basis of RULER, into their everyday practices and into classroom curricula across grade levels

Postdoctoral position in Membrane Signaling in Mammalian Fertilization (Chung Lab)
Posting Date: April 7, 2021

A postdoctoral position is available in the laboratory of Jean-Ju Chung in Department of Cellular & Molecular Physiology at Yale School of Medicine in New Haven, Connecticut. The Chung lab studies cellular signaling in sperm capacitation and fertilization under normal and pathophysiological conditions using insights from human genetics and mouse models (www.jeanjuchunglab.org). One of current focus is membrane signaling via ion channels and membrane receptors in gametes and gamete interaction. Highly motivated and independent candidate with an inquisitive nature and a quantitative mind are encouraged to apply.

Candidates must have

  • A recent PhD or MD/PhD degree (or candidate) in Biochemistry, Molecular, Cell and Developmental Biology or Reproductive Biology
  • Strong publication record (first author papers in peer-reviewed journals).
  • Strong background in protein biochemistry, advanced imaging techniques and/or experience with mice gametes and embryos.

The ideal applicant will be pursuing an independent scientist and have excellent organization skills, written and verbal communication skills, and willingness to write grant proposals and manuscripts.

To apply, please send a single PDF file to Jean-Ju Chung at jean-ju.chung@yale.edu including

(1) a cover letter with a statement of research interests and career goals, (2) curriculum vitae, and (3) a list of three references with contact details.

Postdoctoral position in Regenerative/Cancer biology ( Dean Yimlamai Lab)
Posting Date: April 5, 2021

Research in the Yimlamai Lab is directed at understanding the drivers of human liver disease, particularly in Pediatric diseases such as biliary atresia and non-alcoholic steatohepatitis. Our focus is in the cell biology of epithelial cells with their microenvironment and we are seeking a motivated, dynamic postdoctoral candidate who is interested in applying cell biology, organoid and animal model approaches to understanding fundamental mechanisms in liver biology. As a member of the Yale Liver center, lab members have access to the Morphology cores with State-of-the-art cell and molecular imaging facilities. During this time, the successful applicant will obtain further training on in vivo models as well as a range of cell and molecular biology techniques.

The candidate will be expected to have an MD, PhD, or MD/PhD with experience in cellular and molecular biology. Preference to candidates with involvement in liver pathophysiology will be given, but it is not a requirement. The successful candidate will have the capacity for independent evaluation of the literature. Prior knowledge in cell culture techniques, primary cell isolation/culture, flow cytometry and imaging techniques would be an added benefit. For more information on our group, please see our website – www.liverstemcells.org.

Interested applicants should send a brief statement of interest and curriculum vitae with contact information for three references to the Principal Investigator, Dr. Dean Yimlamai - dean.yimlamai@yale.edu.

Postdoc position in Biochemistry and Structural Biology (Bleichert lab)
Posting Date: March 30, 2021

The Bleichert lab in the Department of Molecular Biophysics and Biochemistry at Yale University is looking for a highly motivated, goal-driven, and team-oriented postdoctoral associate to join our young and collaborative team. Research in the lab is focused on understanding fundamental mechanisms of chromosome replication and genome stability using interdisciplinary approaches ranging from reconstitution biochemistry, biophysics, structural biology (both cryo-EM and X-ray crystallography), to proteomics. Yale provides an excellent infrastructure for high-resolution cryo-EM with access to a Titan Krios (with K3 detector) and several Glacios TEMs (with K2 detector).  

We offer a dynamic and stimulating work environment for conducting cutting-edge research and for facilitating your career development. We will provide numerous opportunities for training you in complementary techniques, and you will also have the opportunity to enhance your own mentoring and teaching skills by interacting with PhD students and by supervising undergraduate students. Our goal is to provide you with the mentoring and resources to launch your own independent career.

Interested candidates should have recently finished or will soon complete their PhD degree and have a strong research track record. Scientific curiosity and excitement to ask challenging questions is a must. While prior experience in biochemistry, biophysics, structural biology, or proteomics are advantageous, we welcome researchers from all backgrounds.

Qualified candidates should send their CV, a cover letter describing past and future research interests, and the contact information for two to three references to franziska.bleichert@yale.edu.

Postdoctoral position in the Curatorial Division at the Yale Center for British Art
Posting Date: March 29, 2021

The Yale Center for British Art (YCBA) is offering a Postdoctoral Associate position of up to three-years duration in the Curatorial Division. The position is for recent recipients of the PhD (degree granted within the last three years) in the field of British art. The PhD must be completed by the time the position begins and it is expected that the research associate will pursue long-term professional employment during the period of hire.

The Postdoctoral Research Associate will report to the Deputy Director and Chief Curator and contribute to the activities of the Curatorial Division. Specific projects will include the development of an exhibition on the artist Hew Locke alongside a complimentary collections display selected in collaboration with the artist. The Postdoctoral Research Associate will help to curate a display of works by Marc Quinn, undertake research on works in the collection, and collaborate with the Deputy Director and Chief Curator on the reinstallation of the Center’s permanent collection. Additional duties will include writing labels and developing scholarly programs and teaching materials in support of major projects. The postholder will occasionally mentor student interns and participate in programs organized by the Curatorial Division. One day per week will be allotted to pursue personal research in the postholder’s own area of specialization. Limited funds will be available to enable the Postdoctoral Research Associate to present annually at a professional conference.

The closing date for applications is June 7, 2021. Interviews are expected to take place in July.

Application materials should be sent by email and need to include: cover letter, CV, recent writing sample. Two letters of reference should be emailed directly from the referees. Please send all application materials to ycba.paintings@yale.edu, with the subject line Postdoctoral Research Associate Application. For enquiries about the position, please contact martina.droth@yale.edu .

Postdoctoral position at the Liver Center in the Section of Digestive Diseases (Vilarinho Lab)
Posting Date: March 29, 2021

The Vilarinho lab is seeking highly motivated and dedicated individuals who are passionate about advancing the cellular and molecular understanding of liver function in health and disease. The Liver Center provides a stimulating training environment, as well as many collaborative opportunities. Our laboratory is interested in using human genetics and genomics paired with highly informative cohorts of patients to discover new liver disease genes. Using cell based and mouse models as well as biochemistry tools we study how a mutant gene causes the liver phenotype. Thus, by uncovering new liver disease genes, we provide a diagnosis leading to new therapeutic options, and we gain new insight into liver biology.

The postdoctoral training may involve biochemistry, molecular biology, flow cytometry and cell culture methodology, primary cell isolation from mouse models, regular presentation at weekly lab meetings, and figure and manuscript preparation. It may also include mentoring and supervision of undergraduate and postgraduate students.

Successful candidates should have backgrounds in cell and molecular biology, biochemistry, genetics and genomics or other related fields. Individuals with a track record of publications, training in liver biology, iPSC biology and/or bioinformatics and recent PhD graduates are strongly encouraged to apply

If you are interested in this position, please send your CV and a statement of why you are interested in the lab to silvia.vilarinho@yale.edu.

Postdoctoral position in the Department of Anesthesiology (Benveniste lab)
Posting Date: March 29, 2021

We have an opening for a talented and highlight motivated Postdoc for a 1-year (with potential extension for 2-years) position. The Benveniste lab in the Department of Anesthesiology at Yale University focuses on translational research of neurodegenerative disorders such as cerebral small vessel disease and Alzheimer’s disease Specifically we study the roles of cerebrospinal fluid flow dynamics and glymphatic-lymphatic coupling and explore novel disease modifying therapies. The lab uses a combination of magnetic resonance imaging (MRI), physiological interventions in transgenic and surgical rodent models together with molecular/histological tools.

The successful candidate will have hands-on experience in a variety of in vivo and histological processing techniques in particular multiplex immunohistochemical staining of brain and lymph node tissue to support our various projects. The candidate must be proficient in immunohistochemistry/ immunofluorescence staining, perform statistical calculations and data analysis. As a member of the research staff, you will assist Dr. Koundal. Dr. Benveniste and research staff in the lab with the following:

Principal Responsibilities:

  • Assist lab staff with research experiments including non-survival and survival surgery (e.g., lymph vessel ligations, CSF catheter implantation, arterial cannulations), brain dissection and slice preparation
  • Using and understanding a wide variety of histological technique
  • Working with and handling research animals
  • Perform multiplex immunohistochemical staining of rodent brain and lymph node tissue in support of various research projects. Also, must have prior experience in fluorescence microscopy
  • Participate in laboratory meetings and read literature applicable to the research area
  • Help with lab organization and other support duties relating to lab operations, as required
  • Other duties as assigned.

Preferred Qualifications:

  • Bachelor’s degree in Biology or a related field
  • Prior experience working in a research laboratory
  • Excellent analytical, communication, problem solving, and organizational skills

Ability to work both independently and as a team memberAble to learn and perform new techniquesExperience in multiplex immunohistochemistry/ immunofluorescence staining of rodent brain and lymph node tissue.

To Apply:

Please submit a CV and cover letter stating your interest in the position to sunil.koundal@yale.edu or helene.benveniste@yale.edu 

Postdoctoral position in Head and Neck Cancer Research
Posting Date: March 24, 2021

A Postdoctoral Associate position is available in the laboratory of Dr. Barbara Burtness at the Yale Cancer Center, Medical Oncology, Yale University School of Medicine, New Haven, USA. Dr. Burtness’ laboratory focuses on translational cancer research to identify novel therapeutic strategies for the treatment of head and neck cancer, across an extensive research program on targeting cell cycle-related kinases, drug resistance mechanisms and immuno-oncology. This postdoctoral associate will mainly work in wet-bench-based cancer cell biology, molecular biology and in vivo study of tumor models, to understand mechanisms of drug resistance and develop of new therapeutics to treat drug-resistant head and neck cancer, funded by NIH/NCI and NIDCR, DOD, and foundations. Our lab provides a collaborative environment within the university and with external partners. This position will provide multi-disciplinary training for scientific and career development, including opportunities for national/international conference presentations and publication of first-authored original articles.

The postdoctoral training may involve (a) the development and application of genetic screening tools, such as CRISPR/Cas9 libraries, (b) bioinformatic analysis of in house/publicly available genomic datasets, (c) a translational approach using human tissue samples and animal models, (d) wet-bench methods in biochemistry, molecular cell biology and immunology, (e) collaboration with other researchers both inside and outside of Yale, (f) presentation in international conferences, and (g) manuscript preparation and grant applications.

The postdoctoral associate will be mentored directly by Dr. Burtness, with possible co-mentorship from qualified Yale Cancer Center faculty members, or others in the Fox Chase Cancer Center. Applications will be accepted until the position is filled.

Candidates are expected to have (a) a recent PhD degree (<4 years or current PhD students graduating by May 2021) in cell biology, cancer biology, molecular biology, immunology, or a related discipline, (b) hand-on research expertise with animal handling skills (cell culture, transfection/transduction, qRT-PCR, cloning and western blotting, immuno-staining, confocal microscopy, flow cytometry, murine tumor modeling, injections and breeding), (c) first-authored original publication(s) in peer-reviewed journals, (c) independence to lead a project as well as willingness to work as a team player, and (d) good scientific oral presentation and writing skills. Previous experience in organoid culture or tumor immunology is preferred but not required. Previous experience or strong interest in programming languages such as R or Python is highly preferred.  

Please send a CV, statement of interest and 2 potential references to barbara.burtness@yale.edu

Postdoctoral position in Reproductive Immunology (Laboratory of Dr. Vikki Abrahams) in the Department of Obstetrics, Gynecology & Reproductive Sciences
Posting Date: March 23, 2021

The laboratory of  Dr. Vikki Abrahams, PhD in the Department Obstetrics, Gynecology & Reproductive Sciences at Yale School of Medicine is looking to recruit a motivated Postdoctoral scientist.

The Abrahams Lab focuses on understanding the role of innate immune Toll-like receptor, Nod-like receptor and inflammasome family members in placental, fetal membrane, and maternal-fetal immune responses to infectious and non-infectious stimuli, and their role in regulating pregnancy outcome, including those complicated by infections and by autoimmune diseases. The lab uses basic and translational approaches; primarily in human models systems and samples, but also using animal models. The current position will involve studying the mechanisms by which antiphospholipid autoantibodies trigger placental trophoblast inflammation and communication with the maternal vasculature. The position is for 2 years initially and is anticipated to start summer-fall 2021. 

Applicants should have a PhD in a relevant field such as Immunology; Reproductive Sciences; or Cellular and/or Molecular Biology. Prior Reproductive Immunology and/or Reproductive Biology experience is preferred but not essential. Applicants should have skills that include, but are not limited to cell culture, Western blot analysis, ELISA, and qRT-PCR.

Candidates should be enthusiastic, highly organized, self-motivated, hard-working and reliable, with excellent interpersonal and written and oral communication skills. Applicants must have good attention to detail and problem-solving skills, be able to multi-task, and be able to perform both independently as well as in a team environment. Successful applicants will have a strong track record of research productivity, presentations, and publications.

Applicants should email: 1) a Curriculum Vitae; 2) contact information for three references; and 3) a description of their research background and interests and career goals to Dr. Vikki Abrahams (vikki.abrahams@yale.edu)

Postdoctoral position in Pediatric Psychology (Yale Child Study Center)
Posting Date: March 17, 2021
The Yale Child Study Center, in collaboration with Yale New Haven Children’s Hospital, is offering a full-time Pediatric Psychology Postdoctoral Fellowship position for the 2021-2022 training year. Clinical training activities will take place within the pediatric floors, our inpatient psychiatric unit, the pediatric emergency room, several ambulatory specialty clinics, and the Child Study Center’s outpatient clinical services.
The mission of the Yale Child Study Center is to improve the mental health of children and families, advance the understanding of their psychological and developmental needs, and treat and prevent childhood mental illness through the integration of research, clinical practice, and professional training.
The Yale Child Study Center Psychology Training Program takes a scientist practitioner approach to clinical training and seeks to prepare professionals to successfully address the complexities associated with children and families who are psychologically vulnerable. Those trained at the Center work within traditional and nontraditional settings and are trained to embrace diverse roles and responsibilities. An over-riding goal is to demonstrate to fellows, through a combination of applied and didactic experiences, that provision of mental health services to children requires intervention at multiple and interacting levels of influence. Our aim is to prepare future leaders in the areas of clinical service, research, training, policy development and prevention services.
 
Fellowship Rotations:
-Inpatient Pediatric Consultation-Liaison Service: The postdoctoral fellow will work for one full year with the Yale Child Study Center’s multidisciplinary Pediatric CL Service. The C/L Service provides a range of behavioral health services to medically ill children and adolescents for all pediatric inpatient services at Yale New Haven Children’s Hospital.
-Specialty Clinics: The postdoctoral pediatric fellow will provide neuropsychological evaluations as part of the Child Study Center Pediatric Neuropsychology program for 12 months. Additionally, the fellow will provide a range of psychological services in several outpatient pediatric specialty clinics for two-days per week for 6-month rotations (e.g. neurology clinic, gender clinic). There will also be opportunities to co-lead the Comfort Ability Program (https://www.thecomfortability.com/) for pain management.
-Pediatric Emergency Department: The Child Study Center provides crisis evaluation and consultation to the Pediatric Emergency Department at Yale-New Haven Hospital. The postdoctoral fellow will work 1 day/month within the pediatric emergency department conducting these assessments, which are completed in collaboration with hospital social work staff and pediatricians within the ED.
-Children’s Psychiatric Inpatient Service: The postdoctoral fellow will have a 6-month rotation on the Children’s Psychiatric Inpatient unit in which they will serve as a primary clinician. As primary clinicians, fellows develop skills in evidence based individual psychotherapy, as well as behavior consultation for the unit staff in designing therapeutic interventions. The fellow will be a member of the multidisciplinary team comprised of child psychology, child psychiatry, social work, pediatric nurses, special education teachers, and recreation therapists.
 
Curriculum: The training curriculum consists of both generalist and specialized training in assessment, treatment, consultation, knowledge of childhood disorders, and professional development.
Fellows Seminar: Fellows meet weekly with the training director and other faculty to discuss a broad range of clinical and professional issues relevant to the practice of psychology, such as: advances in assessment and treatment, diversity and anti-racism, models of consultation, theories of supervision, and program evaluation, career planning, job preparation, and EPPP study approaches.
Clinical Supervision: In keeping with the multidisciplinary orientation of training at the Child Study Center, fellows may receive supervision from professionals from varied disciplines. Currently, each fellow receives approximately 3 hours of individual supervision each week. An individual supervisor is provided for each pediatric/hospital area of practice.
Pediatric Consultation Liaison Seminar: The fellow participates in a multidisciplinary seminar which covers a range of topics related to assessment approaches and evidence-based practices in pediatric settings.
Departmental Conference: Theoretical, research and clinical work by faculty, trainees, and outside speakers are presented in a Grand Rounds format. All Child Study Center faculty and trainees attend this weekly conference.
 
Eligibility:
 Successful completion of the doctoral requirements and internship requirements of APA approved doctoral programs and internships is strongly preferred. Completion of the dissertation defense before beginning fellowship is required. Preference is given to individuals that have previous clinical experience in pediatric psychology, especially in a hospital setting.
 
Postdoctoral Fellows are paid $50,629 for a full year. Postdoctoral fellows pay a fee of $50 per month for individual health coverage through Yale Health. Four weeks of vacation/personal time, all Yale holidays, and a holiday recess between Christmas and New Year’s Day are granted to all trainees. Finally, all psychology trainees are appointed Fellows of the Yale University School of Medicine. With this appointment, they receive all the privileges and rights of membership in the Yale University community including access to libraries and other facilities.
 
Salary and Benefits:
Postdoctoral Fellows are paid $50,629 for a full year. Postdoctoral fellows pay a fee of $50 per month for individual health coverage through Yale Health. Four weeks of vacation/personal time, all Yale holidays, and a holiday recess between Christmas and New Year’s Day are granted to all trainees. Finally, all psychology trainees are appointed Fellows of the Yale University School of Medicine. With this appointment, they receive all the privileges and rights of membership in the Yale University community including access to libraries and other facilities.
 
Application Procedures:
1. Submit a letter of interest describing previous clinical training, highlighting experience providing therapy and psychological assessment with children, including experience in pediatric settings, and outlining specific training goals. Include a description of eligibility for post-doctoral fellowship (i.e. internship completion date, dissertation status).
2. Curriculum Vitae
3. Three letters of reference
4. Written Work Sample: Comprehensive Psychological Assessment Report
 
Review of applications will begin immediately and continue until the position is filled.
The preferred start date is July 1, 2021, with flexibility to start in August.
 
Submit your application materials to our administrative assistant: Tasha.Brooks@yale.edu
Postdoctoral position analyzing immune responses in autoimmunity in the Department of Immunobiology
Posting Date: March 17, 2021

The laboratory of Dr. Kevan Herold in the Immunobiology Dept at Yale University is looking to recruit a motivated Postdoctoral scientist to join our team.  

The Herold lab advances immunology through its focus on understanding the mechanisms of autoimmune disease, primarily Type 1 diabetes. Our studies are translational but involve both the use of human samples and animal models, including humanized mice, where needed to address mechanistic questions. The position is focused on understanding the changes in autoreactive T cells following immune therapies, specifically to identify changes in their numbers, phenotypes and activation, and the pathways that are modulated by the therapy. The samples are acquired from patients receiving anti-T and B cell therapies. The qualified candidate will receive the following while in this position:

Training – The individual will receive training in methods used to analyze research samples by flow cytometry, molecular studies, and with cell culture techniques. If the postdoc has not previously had training in bioinformatics, he/she will be encouraged to learn these methods through course work or other educational opportunities at the University.

Mentoring – The PI (Dr. Herold) will mentor the trainee. In addition, there are members of the laboratory who will provide training in methods.

Education - A PhD in relevant fields such as Immunobiology is required and skills that include, but are not limited to cell culture, flow cytometry, and basic molecular methods. Experience with more advanced molecular methods such as RNA-seq and single cell RNA-seq are preferred.

Interested candidates should email their CV and cover letter, with the words “Postdoc Opportunity in the Herold Lab” in the subject line, to dana.kalina@yale.edu to be considered. 

Postdoctoral position in Breast Cancer Research in the Yale Cancer Center
Posting Date: March 15, 2021

Postdoctoral position is available for recent PhD or MD graduates in the laboratory of Dr. Lajos Pusztai, Section of Medical Oncology, Department of Medicine, Yale University School of Medicine.

The successful applicant will work together with bioinformaticians and clinicians on translational research projects in breast cancer. Independence, creative thinking, and motivation are required. Our lab works on identifying novel therapeutic targets for breast cancer through the analysis of the cancer genome and performs functional studies in in vitro an in vivo models.

Desired skills include experience in applying a wide range of molecular and cell biology tools and ability to adopt and learn new methods. Experience in analysis of metabolic pathways and high dimensional gene expression and DNA sequence data is desirable.

Please send CV and list of references to: Lajos Pusztai, MD, DPhil, email: lajos.pusztai@yale.edu

Postdoctoral position to Study the Dynamics of Immunity to SARS-CoV-2
Posting Date: March 15, 2021

A postdoctoral associate position in mathematical/statistical modeling of SARS-CoV-2 immune responses and correlates of protection is available within the Department of Epidemiology of Microbial Diseases at the Yale School of Public Health in collaboration with the Department of Biology and the Emerging Pathogens Institute and at the University of Florida.

Environment

The Department of Epidemiology of Microbial Diseases at the Yale School of Public Health has a tradition of applying advanced laboratory and analytical approaches to integrated community and patient-based investigations for the purpose of delineating the transmission dynamics and evaluating interventions to emerging and neglected infectious diseases, such as Zika, dengue and leptospirosis. It has played a leading role in the public health and research response to the COVID-19 pandemic in the US and internationally.

Job description
We are seeking a postdoctoral associate to analyze longitudinal data from a cohort of individuals infected by SARS-CoV-2. The Yale Schools of Public Health and Medicine and the University of Florida are collaborating to study the dynamics of immune responses to SARS-CoV-2 infection and vaccination. The postdoctoral associate will be based at the Yale School of Public Health and work under the supervision of both Dr. Albert Ko, Department Chair of Epidemiology of Microbial Disease at the Yale University School of Public Health, and Dr. Derek Cummings, Professor in the Department of Biology and the Emerging Pathogens Institute at the University of Florida. There will also be opportunities to work with other members of the project team, including Dr. Wade Schulz, Assistant Professor and Director of Informatics and the Center for Computational Health at Yale. The overall goal of the research is to describe the long-term trajectory of the SARS-CoV-2 pandemic and the effect of vaccines and to refine understanding of the contribution of immune status and function to the risk of multiple outcomes upon SARS-CoV-2 infection. The main research objectives for the postdoctoral position are to develop mathematical and statistical models to analyze longitudinal measurements of immune responses to SARS-CoV-2, measure vaccine effectiveness, identify correlates of protection from infection and disease and understand the contribution of other individual level factors associated with immune responses and risk of COVID-19.

Required skills and qualifications:

  • PhD in one of the following areas: epidemiology, mathematics, statistics, immunology, physics, computer science, population biology or a similarly quantitative discipline.
  • Research experience with mathematical and/or statistical models.
  • Excellent verbal and written communication skills.
  • Strong interest in infectious disease epidemiology.
  • Ability to collate and analyze data, interpret and present results to a high standard using a range of specialized research techniques.
  • Good knowledge of R.
  • Experience in communicating research findings to a non-specialist audience.
  • Ability to work independently but also as part of a larger interdisciplinary research team.

This will be a one-year appointment with the possibility to extend, should both parties agree.

To apply, please submit a CV, statement of interest, and contact information for 3 references.  Please apply online: http://apply.interfolio.com/85223

For questions, please email Ryan Borg (ryan.borg@yale.edu).

Postdoctoral position in the Department of Immunobiology (Herold Lab)
Posting Date: March 10, 2021

We have an opening for a post-doc position in the Herold Laboratory at Yale University in the Department of Immunobiology. The laboratory is focused on understanding the mechanisms of autoimmune disease, primarily Type 1 diabetes. Our studies are translational but involve both the use of human samples and animal models, including humanized mice, where needed to address mechanistic questions.

Position Description

The position is focused on understanding the changes in autoreactive T cells following immune therapies, specifically to identify changes in their numbers, phenotypes and activation, and the pathways that are modulated by the therapy. The samples are acquired from patients receiving anti-T and B cell therapies.

Education

A PhD in relevant fields such as Immunobiology is required and skills that include, but are not limited to cell culture, flow cytometry, and basic molecular methods. Experience with more advanced molecular methods such as RNA-seq and single cell RNA-seq are preferred.

To Apply

If interested, please send CV and contact information to:

Kevan Herold, MD

Professor of Immunology and Internal Medicine

Yale University

300 George St, #353E

New Haven, CT 06853

Postdoctoral position in Pediatric Depression and Suicidality Clinical Trials
Posting Date: March 8, 2021

The Developmental Affective Neuropharmacology (DAN) Lab and Pediatric Treatment Resistant Depression Program at the Yale Child Study Center seek a highly qualified post-doctoral associate to participate in cutting-edge clinical research on adolescent depression and suicidality. This NIMH-funded work assesses novel interventions for treatment-resistant affective disorders in adolescents and incorporates assessment of neuroimaging biomarkers into clinical trial designs.

The DAN Lab at Yale is hiring a post-doctoral associate for training in the context of a clinical trial that tests ketamine as an anti-suicidal agent in teenagers with treatment resistant depression and suicidal thinking, incorporating fMRI imaging to identify biomarkers predictive of treatment response. Responsibilities will include conducting diagnostic and clinical assessments of teenagers with depression and suicidality, providing oral and written clinical feedback to families, and conducting longitudinal assessments of mood and cognition, as well as other research activities within the Yale Pediatric Treatment Resistant Depression Program. Applicants should have experience in the clinical and diagnostic assessment of adolescents with affective disorders; clinical trial experience in adult or pediatric depression is appreciated, but not required.

As part of the broader study, the post-doctoral associate will be part of an interdisciplinary research team conducting a wide range of longitudinal assessments, including diagnostic, observational, and fMRI measures. As part of the appointment, there will be opportunities for supervising post-graduate associates with clinical training, as well as potential for participation in research dissemination through publication or conference presentations. There may also be opportunities to accrue clinical hours for those who are pursing licensure. We are seeking a two-year commitment (all initial appointments are one year, with the potential for renewal).

Eligibility Requirements
(1) Excellent interpersonal and clinical skills; (2) Doctoral degree in clinical, developmental, or school psychology, with emphasis on pediatric mood disorders; (3) Clinical assessment experience with adolescents with psychiatric illness; (4) Preferable research reliability in clinical depression scales such as the Montgomery Asberg Depression Scale (MADRS) and the Children’s Depression Rating Scale-Revised (CDRS-R)
 
Application Information
A complete application includes the following items (please include your full name on every page of your application):
1. Letter of interest
2. Resume or CV
3. Names and contact information for two references
4. Written work sample (de-identified) of a mood disorder assessment
 
Due to the COVID-19 pandemic, please submit applications via email to jennifer.dwyer@yale.eduReview of applications will begin immediately and continue until the position is filled.
 
Submit your application with the subject line: LAST NAME_Position Title (e.g., SMITH_Clinical Post-Doc). For additional questions, interested applicants should contact jennifer.dwyer@yale.edu or call (203) 433-2788.
Direct applications to:
Jennifer Dwyer, M.D., Ph.D.
Assistant Professor of Child Psychiatry and Radiology and Biomedical Imaging
Co-Director, Yale Pediatric Treatment-Resistant Depression Program
Principal Investigator, Reducing Adolescent Suicide Risk: Safety, Efficacy, and Connectome Phenotypes of Intravenous Ketamine
Postdoctoral position in Computational Healthcare Research: Clinical AI and Data Engineering
Posting Date: March 5, 2021

The successful candidate will be working in a team-oriented environment within the Yale School of Medicine Department of Laboratory Medicine studying a wide array of disease states using the innovative applications of data science tools. Clinical areas of interest range from COVID-19 (immune response factors, protection afforded by both natural infection and vaccine derived immunity, and reinfection risk factors) to oncology with the application of high-throughput data analysis pipelines, clinical predictive models, and data visualization techniques.

Mentoring:

We are seeking a postdoctoral associate to work within our team of informaticians, physicians, and computational scientists. The postdoctoral associate will be based in the Department of Laboratory Medicine and will report directly to Dr. Wade Schulz, Assistant Professor; Director of Informatics, Laboratory Medicine; Director, CORE Center for Computational Health, Center for Outcomes Research & Evaluation (CORE). The associate will also be interacting with other collaborators both within and outside of Yale University, including Dr. Albert Ko, Department Chair of Epidemiology of Microbial Disease at the Yale University School of Public Health, and Dr. Harlan Krumholz, Director, Center for Outcomes Research and Evaluation (CORE).

Training:

The postdoctoral associate will be responsible for collating, analyzing, interpreting and presenting results of various studies being conducted. Training will focus on the translation of real world data to evidence to elucidate clinical disease states, facilitate patient care and improve outcomes. The use of advanced computational frameworks will be a focus of the training, including Spark and various machine learning libraries. The use of common data models, such as OMOP, and the integration of electronic health record (EHR) and laboratory information systems (LIS) data into these models, will be key aspects of the training. Machine Learning, AI, and statistical concepts and skills will be developed and used to evaluate the clinical conditions and outcomes being investigated by the study by the team.

Education, Qualifications and Skills:

  • MD, PhD, or MD/PhD with research experience in one of the following areas: epidemiology, bioinformatics, biostatistics, immunology, microbiology, public health, computer science, cancer biology or a similarly quantitative discipline.
  • Health care exposure and experience with medical terminology
  • Research experience with mathematical and/or statistical models.
  • Strong interest in computational healthcare, clinical informatics, and data engineering
  • Ability to collate and analyze data, interpret and present results to a high standard using a range of specialized research techniques.
  • Good knowledge of Python, R, version control, and distributed computing systems.
  • Excellent verbal and written communication skills.
  • Experience in communicating research findings to a non-specialist audience.
  • Ability to work independently but also as part of a larger interdisciplinary research team.

This will be a one-year appointment with the possibility to extend, should both parties agree. Interested candidates should email Wade Schulz (wade.schulz@yale.edu) and David Ferguson (david.ferguson@yale.edu) with a CV, statement of interest and contact information for 2-3 references.

Postdoctoral position in the Department of Pathology ( Liu Lab)
Posting Date: March 2, 2021

The Liu Research Lab in the Department of Pathology at Yale University has an opening for a postdoctoral position.  The lab is focused on understanding the pathogenesis and immunobiology of human solid tumors using quantitative pathology, genetic/epigenetic analysis, in vitro/in vivo cell models, and molecular biology to interrogate relevant immunomodulatory pathways and identify determinants of sensitivity and resistance to treatments, as well as to develop novel therapeutic approaches for cancer. Our lab has access to cutting-edge technology and has unique opportunities to develop translational research projects in human liver and other GI cancers.  More information can be found at https://medicine.yale.edu/lab/chen_liu/research/

We are looking for a highly motivated individual interested in studying cancer immunology and/or cancer epigenetics. Interested applicants should hold a Ph.D. or MD/Ph.D. degree and a strong background in the field of immunology and/or translational oncology. The candidate should be self-motivated with a proven track record of productivity.  In addition to individual projects, the lab encourages a collaborative and positive working environment with other lab members and throughout the University and Cancer Center.

The competitive candidate should have knowledge and expertise in the following areas:

  1. Immune-oncology and immunomodulatory therapies
  2. Solid tumor oncology, cancer epigenetics, and translational pathology
  3. Advanced cancer diagnostics and immune-based anti-cancer therapeutics
  4. Computational analysis of images and large datasets (optional, but preferred)

Candidates with the following qualifications will be given preference:

  1. Interest and expertise in the field of immune-oncology/cancer epigenetics
  2. Productivity, quality of previous projects and independence
  3. Ability and interest to work in translational research within a multidisciplinary team

Qualified candidates who are interested in applying should e-mail an application package, including; statement of interest, CV, and contact information for three references. Please send your application package to Drs. Chen Liu (chen.liu@yale.edu) or Kien Pham (kien.pham@yale.edu) and in the subject line include your last name and reference to the job posting.

Postdoc position in Cancer Immunology (Lu Lab)
Posting Date: February 25, 2021

A postdoc position is available in Dr. Jun Lu’s laboratory at Yale University School of Medicine. The position is to conduct studies in the exciting field of cancer immunology. Studies will be carried out under existing NIH grants in the laboratory, with the goals of systematically studying epigenetic and signaling regulation in anti-tumor immunity.

The studies will leverage the strengths of the Lu laboratory in cancer, stem cell biology and immunology. Located in the state-of-the-art Yale Stem Cell Center, the Lu laboratory studies non-coding and epigenetic mechanisms in hematopoietic and immune cells. We utilize multidisciplinary tools including mouse models, functional genomics, biochemistry, single-cell genomics, and cell biology approaches such as live-cell and super-resolution imaging.

Postdocs will receive training on research, research management, mentoring, grant writing and career development. Candidates with strong backgrounds in cancer biology, immunology, hematology, epigenetics or RNA biology are particularly encouraged to apply.

Applicants with a Ph.D., M.D. or expecting such a degree in the next year should submit curriculum vitae and names of three references to Dr. Jun Lu (jun.lu@yale.edu).

Postdoctoral position in Behavioral Neuroscience
Posting Date: February 23, 2021
 
The Kim Laboratory at Yale School of Medicine is inviting applications for a postdoctoral position. The main research objective for this position is to define retinal circuits that regulate defensive behavioral responses to threatening stimuli. To identify such circuits, we will utilize mouse genetics, AAV-based neurocircuitry analysis, confocal microscopy and behavioral tests.
 
The ultimate goal is to understand structural and functional properties of the fear-related visual circuits and elucidate the mechanisms that might be responsible for disruption of such circuitry in fear- and anxiety-related disorders.
 
The ideal candidate for this position would have a strong background in behavioral neuroscience or related field. Familiarity with mouse models, in vivo surgery, and/or computer programming would be a plus.
 
Interested candidates should e-mail their application to in-jung.kim@yale.edu. The application should include: (1) CV with a full publication list, (2) a brief description of research interests, (3) contact information for 2-3 references.
Postdoctoral positions in Mucosal Immunity and Intestinal Inflammation (Dr. Clara Abraham)
Posting Date: February 12, 2021

Investigator: Clara Abraham, MD

Mucosal Immunity and Intestinal Inflammation

Yale University, New Haven, CT

Postdoctoral positions are available for research on mucosal immunity, intestinal immune homeostasis/intestinal inflammation, and innate immunity. 

The laboratory focuses on understanding mechanisms regulating innate immune responses, host pathogen interactions, and immunological pathways regulating mucosal immunity and inflammatory bowel disease. The current position will involve examination of molecular and biochemical mechanisms regulating innate cells and pattern recognition pathways, and in vivo intestinal and intestinal-pertinent immune responses, along with potential cross-talk of intestinal immunity with additional immunological sites. Studies incorporate approaches in both primary human immune cells and mouse model systems. 

Education and experience:  Candidates must have a PhD or equivalent degree with a strong background in cellular and molecular immunology, biochemistry, molecular biology, and mouse models of inflammation.  Experience in examination of intestinal tissues, multiparameter flow cytometry, and genetic modification of model organisms is desired. 

To Apply: Please send curriculum vitae, three names of reference and a one page summary of research background and interests to Clara Abraham, M.D. (Clara.Abraham@yale.edu)

Postdoctoral position in RNA biology and Immunology in the Grace Chen Lab
Posting Date: February 2, 2021

We are seeking postdoctoral fellows to join the laboratory of Dr. Grace Chen in the Department of Immunobiology. The Chen lab investigates the mechanisms and regulation of circular RNAs (circRNAs), a newly identified class of ubiquitous RNAs in essentially all eukaryotes and some viruses. Thus far, circRNAs have been found to function as miRNA sponges, regulate transcription, and act as templates for translation. However, there are still many unanswered questions: What other functions do circRNAs possess? How are circRNAs degraded? What are their interacting proteins? Specifically, we aim to understand how different layers of regulation including RNA modifications and cellular localization affect RNA function to enable new insights into both normal function and how dysregulation leads to disease.

The Chen Laboratory applies molecular, cellular, and chemical biology techniques coupled with next-generation sequencing to address these questions. We aim to generate novel therapies based on our new insight about circRNA function and regulation. For more information, visit gracechenlab.org.

Applicants should have recently completed a Ph.D. degree in molecular biology, chemical biology, immunology or genomics. High priority will be given to those candidates with strong backgrounds in RNA or chemical biology.

Interested applicants please send a brief statement of interest and curriculum vitae with contact information for three references to the PI Dr. Grace Chen at ye.grace.chen@yale.edu.

Postdoctoral position in Computational Immunology (Kleinstein Lab)
Posting Date: February 2, 2021

The Kleinstein Lab (Yale School of Medicine, Department of Pathology) is seeking a highly motivated postdoctoral associate in computational immunology. The successful candidates will work in a highly collaborative environment on systems-level human immune profiling studies, with a specific focus on high-throughput B cell receptor (BCR) and T cell receptor (TCR) repertoire analysis (including bulk and single cell RNA-seq + BCR). For interested candidates, there are opportunities for computational methods development.

The Kleinstein lab (https://medicine.yale.edu/lab/kleinstein) pairs big data analyses with immunological expertise to better understand how the dynamic processes of the immune system affect the course of infection, vaccination and autoimmunity. The lab has developed many widely used analysis methods for high-throughput immune profiling data, particularly transcriptomic and B cell receptor repertoire sequencing data (https://medicine.yale.edu/lab/kleinstein/software). We currently make available the Immcantation tool suite (http://immcantation.org), a start-to-finish analytical ecosystem for high-throughput adaptive immune receptor repertoire sequencing (AIRR-seq) datasets.

The biological applications for this position will be related to ongoing NIH-funded collaborations with several experimental/clinical labs, including:

The Shelli Farhadian Lab: The scientific focus of the Farhadian laboratory is to study the neurological effects of systemic infections. The research group focuses on immune and gene expression correlates and biomarkers of neurological dysfunction during and following acute infection. Studies are primarily translational, involving research participants recruited locally. The postdoc will collaborate on studies generating transcriptomic, including AIRR-seq, datasets to characterize patient cohort biospecimens, including from those with acute and post-acute COVID-19, HIV and other infections, with a goal of understanding central nervous system viral immunity through detailed analysis of cerebrospinal fluid immune cells.

The Kevin O’Connor Lab: The scientific focus of the O’Connor lab is to define the mechanisms by which B cells, and the antibodies they produce, affect tissue damage in autoimmunity. A major goal is to define the mechanisms of autoantibody production in human neurologic autoimmune diseases with the aim of improving therapeutic approaches. Examples of specific projects include characterizing the B cell repertoire (using bulk and single cell RNA-seq + BCR) to understand (i) B cell trafficking between disease specific tissues and blood, (ii) B cell clonal persistence through disease course and treatment, (iii) identify correlates of clinical status, and (iv) defining candidate biomarkers correlating with treatment response.

Other biological areas of focus may include Influenza vaccination, Lyme disease and West Nile Virus infection as part of the NIH HIPC (https://immuneprofiling.org).

The ideal candidate will have strong quantitative and programming abilities (ideally R and Python), along with an interest in applying these skills to problems in immunology. A Ph.D. in a quantitative discipline is desired (Bioinformatics, Computer Science, Statistics, Physics, Applied Mathematics, etc.).

Interested candidates should forward a CV and short description of research interests together with the names and addresses of three references to: steven.kleinstein@yale.edu

Review of applications will begin immediately and will continue until the position is filled.

Postdoctoral position with the Autism Biomarkers Consortium for Clinical Trials (ABC-CT)
Posting Date: February 2, 2021

The Autism Biomarkers Consortium for Clinical Trials (ABC-CT) seeks a highly qualified post-doctoral associate to participate in cutting-edge clinical research on autism spectrum disorder at the Yale Child Study Center. The ABC-CT is a network of leading scientists at five sites (Boston Children’s Hospital/Harvard University, University of Washington/Seattle Children’s Research Institute, Duke University, University of California – Los Angeles, and Yale University). The goal of this consortium is to generate a set of reliable behavioral and psychophysiological tools for use in clinical trials with children with ASD. Specifically, we will be working to integrate diagnostic, behavioral, EEG, and eye tracking methods to create biomarkers that can be used to reduce the heterogeneity of autism and indicate efficacy of treatments.

The ABC-CT at Yale is hiring a post-doctoral associate for clinical training in the context of this multi- site, longitudinal research project examining biomarkers in autism. Responsibilities will include conducting diagnostic and clinical assessments of children with ASD, providing oral and written clinical feedback to families, and providing clinical oversight for families’ participation in the ABC-CT, as well as other research studies within the Yale Autism Program. Applicants should have experience in the clinical and diagnostic assessment of children with ASD and other developmental disabilities.

As part of the broader study, the post-doctoral associate will be part of an interdisciplinary research team conducting a wide range of longitudinal assessments, including diagnostic, observational, eye- tracking, and EEG measures. As part of the appointment, there will be opportunities for supervising post-graduate associates with clinical training, as well as potential for participation in research dissemination through publication or conference presentations. The appointment will be for one year, with the potential for renewal.

Yale University is an Affirmative Action/Equal Opportunity employer. Yale values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected veterans, and underrepresented minorities.

Eligibility Requirements

(1) Excellent interpersonal and clinical skills; (2) Doctoral degree in clinical, developmental, or school psychology, with emphasis in developmental disabilities; (3) Clinical assessment experience with children with autism, including cognitive and diagnostic assessment; (4) Preferable research reliability in the Autism Diagnostic Observation Schedule (ADOS) and the Autism Diagnostic Interview – Revised (ADI-R).

Application Information

A complete application includes the following items (please include your full name on every page of your application):

  1. Letter of interest
  2. Resume or CV
  3. Names and contact information for three references
  4. Written work sample (de-identified) of an ASD assessment

Due to the COVID-19 pandemic, please submit applications via email to   mcp.lab@yale.edu 

Submit your application with the subject line: LAST NAME_Position Title (e.g., SMITH_Clinical Post- Doc). For additional questions, interested applicants should contact mcp.lab@yale.edu or call (203) 737-4586.

Direct applications to:

James McPartland, Ph.D.

Professor of Child Psychiatry and Psychology Director, Yale Developmental Disabilities Clinic

Principal Investigator, Autism Biomarkers Consortium for Clinical Trials

http://www.asdbiomarkers.org http://www.autism.fm http://www.mcp-lab.org

Postdoctoral position in single-cell genomics of HIV-induced immune dysfunction (Ho Lab)
Posting Date: January 29, 2021

The Ho Lab at Yale University School of Medicine (https://medicine.yale.edu/lab/yachiho/) is recruiting motivated, productive, independent, and collegial postdoctoral research associates interested in innovative single-cell genomics on HIV-induced immune dysfunction and HIV persistence. This postdoctoral researcher will combine wet-bench molecular biology methods, dry-lab bioinformatic analysis, and a translational approach using clinical samples from people with HIV. The overall goal is to understand mechanism of HIV persistence and guide the development of HIV cure strategies.

Funded by several NIH grants (R01, R61, and UM1), our lab provides a collaborative environment and multi-disciplinary training for scientific and career development. Our lab has a track record of training postdoctoral researchers: our postdocs have international conference presentations and first-authored original articles (Science Translational Medicine and JCI) within three years after they joined the lab. Our lab members have received New Investigator Award, pilot award, and travel grant in the past three years. Our lab is dedicated to recruiting researchers from a diverse background.

The postdoctoral training will involve (a) the development and application of innovative single-cell RNAseq methods (Science Translational Medicine), (b) bioinformatic analysis of single-cell genomics datasets (see bioRxiv below), (c) a translational approach using blood or tissue samples from humans, (d) wet-bench methods in virology (such as sterile cell culture in an enhanced biosafety level 2 (BSL2+) lab), immunology  (such as flow cytometry), and molecular biology (such as CRISPR, real-time PCR, and western blot)(see Journal of Clinical Investigation), (e) collaboration with other researchers both inside and outside of Yale, including virologists, immunologists, bioinformaticians, computer scientists, and clinicians, (f) presentation in international conferences, and (g) manuscript preparation and grant applications.

A successful candidate will likely have (a) a recent (<4 years) PhD degree in genetics, microbiology, molecular biology, immunology, or a related discipline; (b) a track record of research productivity, as evidenced by first-authored original publication(s) in high-quality peer-reviewed journals; (c) experience in programming languages such as R or python; (d) willingness to work with HIV+ samples following BSL2+ procedures; (e) independence to lead a project as well as willingness to work in a team; (f) an open mind to learn new methods from junior researchers and collaborators; (f) good scientific presentation and writing skills. Previous experience and publications in bioinformatics, immunology, or virology is preferred but not required. A successful candidate should expect the initial scope of work to be similar to our recent work posted at bioRxiv. People who have no interest in bioinformatic analysis should not apply. Salary will commensurate with experience and qualifications.

Interested candidates may send a CV, personal statement, and contact information for three referees to ya-chi.ho@yale.edu. Applications will be reviewed on a rolling basis until the position is filled.

References:

Collora et al., bioRxiv 2021, https://www.biorxiv.org/content/10.1101/2021.01.27.428491v1

Liu et al., Science Translational Medicine 2020, PMID 32404504

Yeh et al., Journal of Clinical Investigation 2020, PMID 32573496

Pollack et al., Cell Host Microbe 2017, PMID 28407485

Ho et al., Cell 2013, PMID 24243014

Postdoctoral position in Energy Economics at The Yale School of the Environment
Posting Date: January 22, 2021

The Yale School of the Environment invites applications for a Postdoctoral Associate in Energy Economics. The successful candidate will work on both their own research in energy economics and support a major U.S. Department of Energy-funded project on the co-adoption of solar photovoltaics and related energy technologies under the supervision of Prof. Ken Gillingham.

The project brings to bear unique data, and will allow a deeper understanding of consumer behavior and the effects on the electricity grid of co-adoption. The hire will be expected to perform econometric analyses, co-author papers, and participate fully in the environmental economics community at Yale. The ideal candidate has a Ph.D. focusing on topics in empirical environmental and energy economics with exceptional research, writing, and verbal communication skills, as well as an inclusive and flexible approach to collaborating with a diverse team of individuals and organizations. This is a one-year position with an expected reappointment for a second year upon satisfactory performance.

Yale values diversity among its students, staff, and faculty and strongly encourages applications from and nominations of women, persons with disabilities, protected veterans, and underrepresented minorities. Consideration of applicants will begin immediately, but applications will be accepted until March 1st, 2021. The start date of the position is negotiable, with the default of a July 1st 2021 start date.

Interested candidates should email a cover letter and their CV, along with a list of at least three references to Kenneth Gillingham, PhD, Associate Professor of Environmental & Energy Economics at kenneth.gillingham@yale.edu.