Yale Postdoctoral Positions

• PhD in Electrochemistry, Chemistry, or Engineering (Mechanical, Materials Science or Chemical), or related field.
• Demonstrated strong experimental skills and ability to work collaboratively with others.
• Familiarity with some of the methods mentioned above is an advantage, but the ability to rapidly learn and implement new methods is more important.

A postdoc position in genome editing is available in Ailong Ke’s Lab at Yale University, New Haven, USA. We are looking for a highly motivated individual with experiences in genome editing and eukaryotic cell engineering. Experience in high-throughput screening, mouse work, or microbial engineering is a plus. This trainee will interact with mechanistic biologists in the lab to convert RNA-guided processes, such as CRISPR-Cas, into novel genome editing applications, and to test their efficacy in various therapeutic settings. Our lab is particularly strong in generating high-quality mechanisms and the follow-up engineering. Research details can be found in our laboratory and departmental web sites.

Representative publications include Nat Chem Biol. 2024 Jul 8. doi: 10.1038/s41589-024-01669-3; Mol Cell. 2024;84(3):463-475; Science. 2022;377(6612):1278-1285; Science. 2022;376(6600):1476-1481; Nature. 2021;598(7881):515-520; Molecular Cell. 2019;74(5):936-950; Science. 2018;361(6397); Nature. 2017;550(7674):137-141; Cell. 2017;170(1):48-60; Nature. 2016;530(7591):499-503.

QUALIFICATIONS: Candidates are expected to have published at least one first-author paper in a reputable journal and hold a Ph.D. or an M.D. degree before arrival. Please send your CV, list of publications, and three recommendation letters to ailong.ke@yale.edu for consideration.

Postdoctoral positions at the Department of Biomedical Informatics & Data Science at Yale School of Medicine

New Haven, Connecticut (USA)

About the postdoctoral project

We are seeking highly motivated postdoctoral researchers in biomedical informatics and data science to work on projects focused on the development of biomedical blockchain, clinical predictive models, and blockchain-based privacy-preserving learning. The focus will be blockchain technology and machine learning, and candidates with at least one of the backgrounds are welcomed to apply.

Candidate requirements

Candidates must have a PhD in Biomedical Informatics, Data Science, Computer Science, or an informatics/engineering-related field (e.g., Health Informatics, Clinical Informatics, Biomedical Engineering, Electrical Engineering). Those in the final stages of their PhD are also eligible to apply. A good understanding of medical data and/or electronic health records is considered an asset. The successful candidate should be capable of working both independently and as part of a team.

Essential skills

Proficiency and hands-on experience in blockchain technology (preferably Ethereum) and/or machine learning.

Solid foundation in computer network and/or data analysis.

Strong programming skills, preferably in Java.

Ability to work collaboratively in an interdisciplinary team.

Good to have

Experience in smart contract development, preferably in Solidity.

Familiarity with cloud computing and shell script.

Knowledge of biomedical blockchain, clinical predictive models, and/or blockchain-based privacy-preserving learning.

Good understanding of medical data and/or electronic health records.

Soft skills

Excellent English, both written and spoken, and strong communication skills.

Ability to work effectively in teams.

Ability and interest in mentoring junior scientists.

Strong problem-solving and critical-thinking skills.

Good time management and organizational skills.

Ability to work independently and take initiative.

About the Supervisor

The primary supervisor for the project is Dr. Tsung-Ting Kuo, a faculty member of Biomedical Informatics & Data Science and of Surgery at the Yale School of Medicine. More about Dr. Kuo can be found here at: https://medicine.yale.edu/profile/tsung-ting-kuo/.

About the department

The Department of Biomedical Informatics & Data Science (BIDS) is a new department at the intersection of health sciences and information technology. It develops new approaches to organize and analyze biomedical and healthcare data to promote health for all. More information about BIDS can be found here at: https://medicine.yale.edu/biomedical-informatics-data-science/

Research Position (Post-doc) in the Department of Immunobiology 

The Sefik Laboratory, located in the Department of Immunobiology at the Yale School of Medicine seeks a highly motivated postdoctoral scholar to engage in cutting-edge research at the intersection of immunology and chronic inflammatory diseases. As a postdoctoral fellow in our dynamic and collaborative environment, you will have the unique opportunity to elucidate the pathophysiology of these complex conditions using state-of-the-art methodologies.

Under the direction of Dr. Sefik and a team of dedicated collaborators, you will utilize humanized organs and humanized mice harboring a human immune system to elucidate the intricate mechanisms underlying chronic inflammation and fibrosis. Through a combination of in vitro and in vivo approaches, you will contribute to advancing our understanding of these diseases, with the ultimate goal of developing novel therapeutic strategies.

In addition to conducting innovative research, as a postdoctoral scholar in the Sefik Laboratory, you will benefit from a supportive and inclusive community that fosters intellectual growth and career development in the Department of Immunobiology and more broadly Yale University. With a strong commitment to nurturing the next generation of scientific leaders in a diverse research community. As such, applicants from all backgrounds are encouraged to apply.

If you are a motivated and passionate scientist eager to make a meaningful impact in the field of immunobiology, we invite you to apply via esen.sefik@yale.edu to join this newly established laboratory and embark on an exciting journey of discovery and innovation.

Preferred Qualifications

• Ph.D. In immunology or a relevant field
• Experience in infectious diseases and/or in vivo mouse models
• Laboratory skills and research experience
• Data analysis skills
• Teaching and/or mentoring experience
• Strong analytical and problem-solving skills
• Excellent written and verbal communication skills

Description:

Multiple postdoctoral research associate positions are immediately available in Dr. Haoyu Cheng’s Lab (https://hcheng-lab.github.io/) at the Department of Biomedical Informatics and Data Science (BIDS) at Yale University, School of Medicine. Successful candidates will engage in the development of innovative computational algorithms for genome analysis. Potential projects include genome assembly, read alignment, variant calling, pangenome analysis, as well as other related research on cancer and plant genomes.

Preferred qualifications:

• Ph.D. in Computer Science, Bioinformatics, Computational Biology, Statistics, Genetics, or a related field.
•  Strong programming skills. Demonstrated experience in developing algorithms using high-performance languages such as C, C++, or Rust is desirable.
• Demonstrated expertise in analyzing large-scale genomic sequence data.
• A strong track record of scientific publications.
• Good oral and written communication skills in English.

How to apply:

Please email your CV to Dr. Cheng at haoyu.cheng@yale.edu with the subject ‘Postdoc Application - Cheng Lab’. Applications will be reviewed on a rolling basis.

About the PI:

Dr. Haoyu Cheng is an Assistant Professor at the Department of Biomedical Informatics and Data Science (BIDS) at Yale University, starting in July 2024. His research primarily focuses on developing computational methods for genomic data, with a particular emphasis on de novo genome assembly and its applications. He has developed a suite of algorithms for de novo genome assembly, including hifiasm (Cheng et al, Nature Methods, 2021), hifiasm (Hi-C) (Cheng et al, Nature Biotechnology, 2022) and hifiasm (UL) (Cheng et al, Nature Methods, 2024). These algorithms have been widely used by numerous large-scale sequencing projects, such as the Human Pangenome Reference Consortium (HPRC), the Genome in a Bottle (GIAB), the Vertebrate Genomes Project

(VGP), and the Darwin Tree of Life project. His works received the recognition of the K99/R00 Pathway award from the National Institutes of Health (NIH). For more information, please see https://hcheng-lab.github.io/

About the Fellowship

The Office of Career Strategy seeks a 12-month full-time STEM Strategic Initiatives Fellow to conduct a landscape analysis of the local biotech industry; assess the potential for a robust talent pipeline between this industry and Yale STEM graduate students and postdocs; and build relationships with industry partners that expand this pipeline.  The position requires a highly motivated individual with a strong sense of initiative and excellent analytical, research and communication skills.

This fellowship offers a unique opportunity to gain valuable experience in strategic analysis, market and competitive research, industry engagement, and project management. You will work collaboratively with OCS staff, faculty, and other stakeholders within Yale and in industry.  It is an ideal opportunity for individuals passionate about bridging the gap between academia and industry and contributing to developing a thriving biotech ecosystem in Connecticut. It is also well suited for those interested in higher education administration, industry, and management careers.  

Goals of the Fellowship

Under the guidance of the Director of Graduate and Postdoctoral Career Services, the Fellow will produce the following:

Market and Needs Assessment: Conduct a comprehensive analysis of the local biotech ecosystem that includes an assessment of key players and their specialization areas, market growth trends, talent needs, and the current talent acquisition challenges faced by local biotech firms.

Stakeholder Engagement: Establish relationships and initiate dialogues with human resource personnel, hiring managers, and other key stakeholders in the local biotech industry. Work with the Yale OCS team to connect students and postdocs with interested employers and promote job and internship opportunities.   

Yale Talent Assessment: Develop an assessment of Yale’s postdocs and Ph.D. graduate students that evaluates their readiness, suitability, and preferences for opportunities in the local biotech industry. Gather data on the career outcomes of Yale postdocs following their Yale appointments via a survey or other method.

Strategic Planning and Program Design: Work with OCS leadership to develop a preliminary strategic plan for a talent pipeline program, including partnership structures and integration with existing educational or professional development programs.

Education and Experience Requirements

Master’s degree (Ph.D. strongly preferred) in the sciences with a strong interest in the biotech industry, and in applying an analytical mindset to real-world, strategic challenges. Research, consulting or industry experience in related disciplines, such as biotechnology, biomedical engineering, biochemistry, biology or physics, is strongly preferred.

• Demonstrated research and analytical skills, including proficiency in gathering, managing, and applying quantitative and qualitative data to inform decision-making. Experience in survey design is helpful but not required.
• Excellent written and verbal communication skills, including presenting complex information to diverse audiences. 
• Experience performing outreach to engage diverse stakeholders and build productive collaborations.
• Strong organizational and time management skills.
• Ability to take initiative and work independently while collaborating effectively within a team.

The salary range for this fellowship position is $65,000 - $85,000.  Information on benefits may be found on this webpage: https://your.yale.edu/work-yale/benefits/benefits-enrollment-2024/postdoctoral-associates-benefits-2024.

To Apply: Candidates should submit their resume and a cover letter outlining their interest in the position and any relevant experience to Hyun Ja Shin, Director of Graduate and Postdoctoral Career Services (hyunja.shin@yale.edu).

Postdoctoral Associate Position – Department of Therapeutic Radiology (Gueble Lab)

The Gueble laboratory in the Department of Therapeutic Radiology at Yale School of Medicine is looking for a highly motivated postdoctoral researcher in translational cancer biology.

Our laboratory seeks to understand and exploit DNA repair abnormalities in cancer with the goal of developing novel anti-cancer strategies.  We are applying a variety of research techniques to study the mechanisms and therapeutic potential of novel DNA modifying agents which take advantage of tumor specific DNA repair defects.  We are also interested in the effect of DNA modifying agents in the context of the tumor microenvironment and in understanding the development of resistance to these agents.  We aim to translate these findings into clinical studies through collaborations within the Yale School of Medicine community.

The postdoctoral associate will develop a research project investigating the mechanisms and therapeutic potential of DNA modifying agents under the mentorship of Dr. Gueble.  Research techniques may include standard molecular biology research assays, tissue culture, mouse xenograft models, genetic manipulation, DNA repair assays, next-generation sequencing, and high-throughput screening assays.  In addition to bench research and data analysis, the postdoctoral associate will participate in manuscript preparation, conference presentations, and development of collaborations with other scientists.

Qualified candidates will have graduated from an PhD or MD/PhD program in a relevant field, such as cellular or molecular biology, cancer biology, genetics, or a similar program.  The candidate must be proficient in cellular and molecular biology research techniques, have a strong interest in translational cancer biology, and be a collaborative and self-motivated scientist.  Prior experience with mouse xenograft models is highly preferred.

To apply, please send a cover letter, curriculum vitae, 1-page research summary, and contact information for three references to:

Susan Gueble, MD, PhD

susan.gueble@yale.edu

Department of Therapeutic Radiology

Yale School of Medicine

Position: Postdoctoral Associate

Department: Pathology

Hiring Faculty: Shaoning Jiang, PhD

A postdoctoral Associate position is available in the laboratory of Dr. Shaoning Jiang in the department of Pathology at Yale University. Research interests of the laboratory focus on epigenetic mechanisms linking inflammation and energy metabolism in the pathogenesis of diabetes and obesity and related metabolic disorders, particularly in the context of developmental origins of health and disease. The candidate will be involved in a recent NIH R01 funded project studying cell-type specific functions of microRNAs in regulating beige and brown fat adipogenesis and crosstalk of adipose stem cells and macrophages. Studies incorporate approaches in primary immune and stem cells, and transgenic mouse models.

Applicants should be highly self-motivated with research experience in cellular and molecular biology, metabolism, and mouse study. Research experience in the fields of immunology, embryology, or stem cell biology is desired (but not required). The candidate must have a PhD degree in a relevant field with a proven record of scientific productivity including at least one first author publication in a peer-reviewed journal. Excellent written and oral communication skills are expected. The candidate will be expected to work independently in the design and execution of experiments with guidance from the principal investigator.

Please send a Curriculum Vitae, and names / contact information for three references to Dr. Shaoning Jiang (shaoning.jiang@yale.edu).

Yale University is an Affirmative Action / Equal Opportunity employer. Yale values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected veterans, and underrepresented minorities.

Postdoctoral Fellow, Material Histories of the Human Record

The certificate program in Material Histories of the Human Record<https://materialhistories.yale.edu/> of the Humanities Program at Yale invites applications for a Postdoctoral Fellow position at Yale University for the 2024-2025 academic year. Candidates must have research, teaching, or curatorial experience relevant to the histories of the book, archival studies, collections-based learning, publication; or cultural heritage stewardship, provenance, book arts, or other relevant field expertise.

This unique opportunity situates the successful candidate within a relevant academic department at Yale and the Yale Library Special Collections. During the two years of this appointment, the Post-Doctoral Fellow will support the Beinecke Library Education program for 15-20 hours per week (the equivalent of one course per semester), work to develop the initiatives associated with the Material Histories certificate in conjunction with the co-directors, and pursue their own research.

The Material Histories certificate program is designed to expose students to multiple forms of expertise within Yale’s special collections libraries, equip emerging scholars with new analytical skills, and teach them the methodologies that scholars, librarians, archivists, conservators, and curators employ as they preserve, interrogate, and steward the human record. This inaugural postdoctoral fellowship is envisioned as a dynamic bridge between the world of libraries, archives, and special collections, and their engagements by faculty, students, artists, and researchers who are located in other parts of the university. The Postdoctoral Fellow must be committed to facilitating these engagements in Yale University’s special collections by the broadest possible group of researchers and support work that utilizes traditional methods of archival and bibliographic research alongside creative, interdisciplinary, and non-traditional approaches to conducting research in the collections.

The Postdoctoral Fellow will:

- support all aspects of the ongoing certificate program
- serve as a resource for graduate and undergraduate students within the program
- oversee publicity, outreach, and communications with the help of an undergraduate student worker
- work to develop programming that engages and creates a sense of community for those involved with the certificate program
- help plan a robust undergraduate certificate curriculum
- develop new initiatives to support the strategic direction, long-term goals, and objectives of the certificate program, including identifying partnerships and collaborations to assist in the development and growth of the program
- contribute to the development and assist in the management of content on the program’s website and monitors all changes and additions to the editorial content

The successful candidate will be intellectually wide-ranging and curious, open to imagining creative solutions and futures for the development of the certificate, have superb analytical, creative, and communication skills in both writing and public speaking, and be an excellent collaborator with the ability to foster collegiality and impart empathy, humility, and a positive outlook in their work. Experience working in an archive, library, museum, or other cultural heritage institution is desirable but not required. This position reports to the co-directors of the Material Histories of the Human Record certificate.

The Postdoctoral Fellow is expected to be in residence in New Haven, Connecticut, for the full duration of the appointment and take an active part in the intellectual exchange with other members of the Material Histories and Yale Library Special Collections communities at Yale. Compensation is competitive and includes benefits and health insurance.
Qualifications
All applicants must have completed their PhD by the time of appointment. Graduate students who are working on their PhDs may apply, but must present proof of having completed and filed their dissertations, even if awaiting formal conferral of the PhD degree. Fluency in English is required, as reading knowledge of at least one other language.
Application Instructions
Applicants should submit a cover letter; a CV; a one-page description of research plans; and a statement of 500-700 words describing their experience and interest in Material Histories of the Human Record (broadly defined). We urge all prospective applicants to read the description of the program on our website<https://materialhistories.yale.edu/> to get a sense of the range of fields we encompass.

Letters of reference are not required at this initial stage but will be requested later.

All information from the applicant should be submitted electronically through Interfolio:

We will accept applications immediately with review beginning on 1 July 2024 and continuing until the selections are final.

For questions, please email: Ayesha.ramachandran@yale.edu<mailto:Ayesha.ramachandran@yale.edu>.

Apply here: https://apply.interfolio.com/146651

Postdoctoral Associate – Germinal Center B Cell Competition and Derived Malignancies (*new* Mlynarczyk Lab)

We are seeking a self-motivated and science-driven postdoctoral associate to join the laboratory of Dr. Coraline Mlynarczyk, opening 7/1/2024 at Yale University. Our lab is part of the Center of Molecular and Cellular Oncology (Yale Cancer Center) and Department of Medicine (Yale School of Medicine), with pending affiliation with the Departments of Immunobiology and Pathology. At the interface between Immunology, Cancer and Metabolism, our inter-disciplinary team will tackle how immuno-metabolic deregulation of germinal centers shapes B cell lymphomagenesis.

Building on our recent discovery of supercompetition as a key mechanism of malignant transformation of germinal center B cells (Mlynarczyk et al Science 2023), (1) the candidate will uncover how reprogramming of T-B immune synapse signals drives B cell competitive fitness in germinal centers and yields B cell lymphomas that are addicted to microenvironmental cues.   Based on the candidate’s prior experience and interests, additional projects will focus on (2) elucidating how germinal center B cells and derived lymphomas satisfy their metabolic needs to sustain intense growth and proliferation; and (3) dissecting the biochemical mechanisms underlying elevated mRNA translation rates in these cells.  Opportunities are also available to develop a novel line of investigation.

Training. The candidate will benefit from the lab’s expertise in precise mouse modelling of the immune response and B cell lymphomagenesis, complex immunological assays, in vivo metabolic flux analyses and high-dimensional flow cytometry. The candidate will carry out functional experiments using mouse models, immune and tumor cells, B cell lymphoma patient-derived xenografts and primary samples. With our collaborators, the candidate will implement state-of-the-art spatial analysis of lymphoid tissues (including single-cell transcriptional and metabolic flux profiles) and single-cell phospho-proteomics.

Mentoring. In the Mlynarczyk lab, each mentee will have short and long-term career development plans and the opportunity to discuss needs, receive and provide feedback yearly (or as needed). Weekly one-on-one meetings will support research progress (focused on experimental design, problem solving, data analysis and interpretation) and continuous development of the mentees. Postdoctoral Associates will write research proposals and receive mentoring for putting together competitive applications, present their work at conferences to engage with the scientific community, contribute to writing manuscripts, publish in peer-reviewed journals and be encouraged to build new collaborations with interdisciplinary experts, locally, nationally, and internationally. Dr. Mlynarczyk has a strong track-record of mentoring postgraduate and graduate students, research technicians and peers, of obtaining peer-reviewed competitive funding and publishing high quality science. Additional mentoring from peers and faculty members will be available from exposure to other labs at Yale and beyond.

Philosophy. We envision to establish ourselves as a new, exciting, and welcoming lab, where everyone can share ideas, provide feedback, and mentor each other. We hope to recruit people that share this spirit and have the desire to facilitate the growth of a new lab and carry out innovative and rigorous science in an evolving field. Discoveries will involve teamwork within the lab and with external collaborators and we are looking forward to fostering a dynamic, diverse, inclusive, and flourishing lab environment, allowing everyone to grow as a scientist and person.

Environment. Our team will initially be composed of 4 members and will grow as our research advances. Our lab is located at 300 George Street, 6^th floor. We share the floor with a combination of young and well-established groups, forming a highly interactive, rich, and vibrant environment for trainees. An open laboratory space, shared floor lounge area and conference rooms will provide the space for fruitful interactions. The newly renovated and fully equipped mouse facility as well as flow core facility are located on the 2^nd floor.  There will opportunities to participate in multi-lab meetings, journal clubs, departmental research-in-progress seminars, and scientific retreats. Additionally, trainees will be integrated into the thriving research, education, and health-care communities as well as training and well-being programs across Yale University.

Qualifications. Applicants must have a recently obtained/upcoming PhD or MD/PhD degree in a relevant field and one first author publication in a peer-reviewed journal. Applicants should have experience in immunology, cancer biology, molecular biology, genetics/genomics or related fields. Experience with mouse work is encouraged but not required if the candidate wants to learn. Most important qualifications are high self-motivation, having a curious mind, enjoying doing science, and excellent written and oral communication skills. Candidates should also be highly organized, honest and reliable, have good attention to detail, be able to multi-task and perform both independently as well as in a team environment.

Responsibilities include:

• Conceptualization, designing and progressive independent execution of experiments to streamline the project’s aims
• Active participation in lab meetings, journal clubs, improving the team’s knowledge
• Providing input and guidance to more junior lab members
• Active fostering of cooperative projects with lab members and external collaborators
• Submitting fellowship applications and contributing to the lab grant proposals
• Helping with lab organization and upkeep, including mouse colony maintenance.

Compensation starts at $68,000 plus benefits. Start date is flexible.

How to apply. Candidates should send an email to coraline.mlynarczyk@yale.edu with “postdoctoral position, candidate’s full name” in the subject line and the following:

1. CV

2. Cover letter: brief statement of research experience, interests, motivation to join our lab and career goals.

3. Representative publications

4. Contact information for 3 references

Interested individuals are also welcome to reach out with any questions. We will review applications on a rolling basis starting June 10.

X (twitter) account @coraline_mly

Website coming soon.

Yale University is an Affirmative Action/Equal Opportunity employer. Yale values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected veterans, and underrepresented minorities.

Postdoctoral Associate in Genomics (Computational)

Yale University, Department of Genetics, Lake Lab.

We are seeking a motivated postdoc to join our growing team in the Yale Center of Genomic Health, Department of Genetics, Yale School of Medicine, the Lake Lab. Our lab uses computational and experimental methods to determine how genetic variation in mitochondria underlie health and disease in humans.

We are specifically looking for a postdoc to spearhead computational projects at the intersection of human genetics and mitochondrial genomics, who will apply and develop new approaches for analyzing genetic variants and their role in disease. We value diversity of backgrounds in our team and seek candidates who can commit to a multiyear appointment, reviewed annually. The start date can be flexible, and as soon as summer 2024.

The lab is in the Yale School of Medicine which offers an outstanding training environment for postdoctoral scientists, with state-of-the-art research facilities and vast resources to support professional development. For more information about our lab and publications see our website: https://www.thelakelab.org/

Responsibilities

• Use bioinformatic tools to analyze large-scale genomics datasets
• Develop and apply methods for analyzing genetic variation
• Prepare high-impact manuscripts for publication and conference presentations
• Attend and present at lab meetings, journal clubs, and departmental seminars
• Contribute to the mentoring of students and junior scientists in the lab
• Assist in the preparation of grant proposals
• Maintain code and pipelines, and support lab operations as needed
• Positively contribute to lab culture

Mentoring & Professional Development

The lab has a strong emphasis on mentorship and values the opportunity to train future leaders in genetics and genomics. The PI will work with the successful candidate to develop and implement a mentorship plan tailor-made for their goals, interests, and needs, and provide ongoing support for the advancement of goals via regular meetings. Mentorship will be provided for fellowship applications, manuscript writing, presentations, and skills for independence. 

The successful candidate will gain access to a range of career development opportunities at Yale. This includes seminars from internationally renowned researchers and ‘Meet the Speaker’ lunches, and professional development and networking activities via the Yale Postdoctoral Association, Yale Office for Career Strategy, and other offices at Yale.

Qualifications

Candidates should have or be close to obtaining a PhD in either genetics, genomics, computational biology, bioinformatics, or a related field.

Experience with programming languages and the command line interface is required. Experience with one or more of the following is desired: large-scale genomic analyses, variant calling, cloud computing, machine learning methods, and or statistical genetics.

The ideal candidate will also demonstrate:

• A high level of drive and initiative, and track record of impactful research outcomes
• Experience writing manuscripts published in peer-reviewed journals
• Ability to work both independently and as part of a team
• Eagerness to learn and establish new methods, and good problem-solving skills
• Excellent communication skills, both written and verbal
• Desire to contribute to the mentorship of students and junior scientists in the lab
• Experience in, or strong understanding of, human genetics research.

Position Information

This is a full-time, in-person position at Yale in the vibrant city of New Haven, Connecticut, with a competitive salary from $68,000 a year and access to a range of benefits.

Application Instructions

Please email (1) a cover letter summarizing your experiences, research interests, and career goals, and why you are interested in pursuing a postdoc in our lab, (2) your CV, including contact details of three references, and (3) when you are available to start, to Dr. Lake at nicole.lake@yale.edu using the subject ‘Postdoc Application - Lake Lab’. Applications will be reviewed on a rolling basis.

Yale University is an Affirmative Action/Equal Opportunity employer. Yale values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected veterans, and underrepresented minorities.

Postdoctoral Associate Position in Pediatric Critical Care Medicine

We are currently seeking full-time Postdoctoral Associates to be part of our NIH-funded research team at Yale. Our research primarily investigates the outcomes following extracorporeal membrane oxygenation (ECMO) in pediatric critical care.

Research Focus:

The successful candidate will support two primary studies:

1. A qualitative study assessing the impact on parents of children undergoing ECMO, with a focus on post-traumatic stress disorders, anxiety, and depression.
2. An international point-prevalence study to examine the epidemiology and risk factors associated with mental health conditions in these parents.

In supporting these studies, the successful candidate is expected to engage in a variety of research activities including drafting the research protocol in collaboration with the primary investigator, submitting the protocol to the Institutional Review Board (IRB), conducting interviews with parents, collaborating on data analysis, coordinating the international study, developing the case report form, analyzing the research data, and drafting manuscripts for publication.

Training, Mentorship, and Career Development:

The role provides significant opportunities for hands-on experience in pragmatic clinical studies, mixed methods research, and collaborative work across multidisciplinary, multi-site teams.

You will work directly under the guidance of Dr. Oliver Karam, MD, PhD, and collaborate with experts in implementation science, health services research, biostatistics, trauma-related psychopathologies, and critical care research.

The position also includes professional development opportunities such as mentorship, participation in national conferences, grant writing support, and engagement with the broader Yale academic community through seminars and events.

Skills and Qualifications:

• MD degree required (completed before the start of the postdoctoral term).
• Experience in pediatrics.
• Excellent communication, analytical, and problem-solving skills.
• Proficient in both quantitative and qualitative research methodologies.
• Ability to work independently and collaboratively.
• Strong project coordination skills, with experience managing studies across multiple regions. Fluency in at least two European languages is preferred.
• Strong interpersonal skills with effective team collaboration capabilities.

Application Process:

Candidates interested in applying should send the following materials to Dr. Oliver Karam, MD, PhD, via email at oliver.karam@yale.edu:

• A brief letter of interest highlighting your qualifications for the role.
• Curriculum Vitae or Resume.
• A first-authored writing sample.
• Contact information for three references.

Appointment Details: This position is a full-time role, lasting six to twelve months, starting in September 2024, with reviews of applications beginning immediately. Please note, the position is non-renewable.

Postdoctoral Associate Position in Metabolic Inflammation

-The Xinshou Ouyang Lab

-Department of Internal Medicine

A postdoctoral associate position is immediately available for a NIH funded project in the Ouyang lab at Yale University, focusing on research related to metabolic inflammation in the context of obesity, insulin resistance, and NASH/ASH. The lab is dedicated to advancing the understanding the core metabolic signaling in the control of inflammation, emphasizing the impact of RNA metabolism on metabolic disease pathogenesis.

Successful candidate will lead exciting new projects in RNA metabolism including RNA epigenetics and RNA binding proteins in metabolic diseases. They will utilize cell and molecular biology methods, advanced techniques (scRNA-seq, eCLIP-seq, etc.), and genetic animal models to uncover the protein function in RNA metabolism at both cellular and organismal levels. For additional information, please visit our website (https://medicine.yale.edu/profile/xinshou-ouyang/).

Qualifications:

• We are seeking candidates with a Ph.D. in cell and molecular biology, immunology, pharmacology, biomedical science, or a closely related field.
• Preferred qualifications include experience in cell culture and animal experimentation.
• Successful candidates should demonstrate strong motivation, ability work independently and in a team, a proven track record of productivity through peer-reviewed publications, effective communication skills, and less than three years of prior postdoctoral experience.

Benefits:

• We offer personalized career development plans and comprehensive training programs for all lab members.
• Yale University provides access to a wide range of resources, including cutting-edge research facilities, specialized centers, and programs to support our members’ success.
• The lab collaborates closely with various Yale entities, such as the Yale Center for Genome Analysis (YCGA), Mass Spectrometry and Proteomics Resource at the W.M. Keck Foundation Biotechnology Resource Laboratory, Yale Metabolomics Facility, Yale Flow Cytometry Facility, Yale Stem Cell Center, and Yale Institute of Biomolecular Design and Discovery.
• We engage in research collaborations with Yale experts in Immunology, Endocrinology, Pharmacology, Yale Center for RNA Science and Medicine, Yale Computational Biology and Bioinformatics, as well as renowned outside institutions like the Massachusetts Institute of Technology (MIT) and the National Center for Advancing Translational Sciences (NCATS).
• The lab has a strong publication record in prestigious journals, including Cell Metabolism, Nature Communication, Science, Journal of Hepatology, Cell Death & Differentiation, Cell Reports, and more.

How to Apply:

To apply, please send a cover letter expressing your interest, your current CV, and the contact information of three references to Dr. Xinshou Ouyang, via email at xinshou.ouyang@yale.edu.

A NIH-funded post-doctoral position is available in the laboratory of Susan J. Baserga, MD, PhD, in the Departments of Molecular Biophysics and Biochemistry at Yale University and the Yale School of Medicine. The successful candidate will be driving research into the mechanistic biochemical and physiological aspects of how ribosomes are made in eukaryotic cells using model systems ranging from human cell lines and mice to Saccharomyces cerevisiae and Xenopus tropicalis. The successful candidate will not only gain extensive experience working in these model systems but will also receive expert career mentoring. They will develop skills in a wide range of basic biochemical and genetic techniques including, but not limited to, high throughput screening, northern blots, western blots, qPCR, subcellular fractionation, co-immunoprecipitation, immunofluorescence and RNA-seq.

Ribosome biogenesis is essential for cells and developing organisms. As such, ribosome production is often dysregulated in cancer and is implicated in a growing number of congenital human genetic diseases known as the ribosomopathies (a recent paper from our laboratory can be found here at Bryant et al PNAS https://www.pnas.org/doi/full/10.1073/pnas.2017777118). We have also uncovered strong evidence to support a role for the nucleolus and ribosome biogenesis in embryonic development, neurodegenerative diseases, cytoskeletal integrity, and DNA repair, among other cellular processes and diverse signaling pathways (see our papers in Cell Reports, 2018; Molecular Biology of the Cell 2021). This year we have published a landmark study on how microRNAs regulate the making of ribosomes (Nucleic Acids Research 2024), leading us in an entirely new scientific direction to relevant questions of human brain development. The successful candidate will conceptualize and design original research among these themes and execute it in an environment that values teamwork, camaraderie, and intellectual curiosity.  

Candidates must be highly-motivated and have a PhD in the biological sciences, with a degree in biochemistry, genetics, cancer biology, developmental biology, or cell biology preferred. A high level of proficiency in basic laboratory techniques is also required.

For more information about the Baserga laboratory please visit our website at https://basergalab.yale.edu/. If you are interested in this position, please send your CV and cover letter to Dr. Susan J. Baserga at susan.baserga@yale.edu.

Postdoctoral Associate Position, School of Public Health and Department of Biostatistics

New Haven, Connecticut

We are actively recruiting a postdoctoral associate to join the Public Health Data Science and Data Equity research team in the School of Public Health with a primary home in the Department of Biostatistics.

The postdoctoral associate will work with Dr. Bhramar Mukherjee, Ph.D, the inaugural Senior Associate Dean of Public Health Data Science and Data Equity, Anna M.R. Lauder endowed Professor of Biostatistics, Professor of Chronic Disease Epidemiology, Professor of  Statistics and Data Science, with a focus on analysis of electronic health records and real world healthcare data and global health. There may also be opportunities for collaboration with faculty with experience in cancer and cardiovascular diseases. The position is for one year, and is renewable for a second year based on satisfactory performance and progress.

The postdoctoral associate will actively participate in methodological and collaborative research and support writing research grants. Professional development will be an integral part of the position. This position offers postdocs the opportunity to develop expertise in analyzing complex non-probability observational samples and get involved in exciting applications harnessing data from multiple different biobanks. The position will also provide a solid foundation to build a research career in academia, government, or industry.

Qualifications:

• Completed doctorate in Biostatistics, Statistics, Data Science, Computer Science, Bioinformatics, or a related field by August 1, 2024
• Strong oral and written communication skills, and the ability to work effectively with a wide range of constituencies in a complex and diverse setting
• Proficiency with statistical computing (e.g., R, Python or C/C++)
• Demonstrated capacity to work both collaboratively and independently
• Strong strategic, analytical, and problem-solving skills
• Strong interpersonal and project management skills to facilitate timely and professional deliverables
• Experience with causal inference, machine learning, and artificial intelligence is desirable

Organization: Yale School of Public Health
Department: Biostatistics

Primary Location: New Haven, CT
Education Level: PhD
Shift: Days, 40 hours/week

Work Modality: Flexible, hybrid working arrangements could be accommodated if needed
Expected Start Date: September 1, 2024

To apply:

Interested individuals should submit a (1) CV, (2) cover letter that addresses their specific interest in this position, skills and experiences directly related to this position, and highlight overall research interests and plan, and (3) contact information for three professional references via Interfolio. Review of applications will begin immediately and will continue until the position is filled.

Please apply online:  http://apply.interfolio.com/144336

Questions regarding this position should be directed to ysphfacultyaffairs@yale.edu.

Additional information on the Yale School of Public Health, the Department of Biostatistics and the Department of Chronic Disease Epidemiology at the School of Public Health can be found via the links below:

About Us | Yale School Of Public Health

Biostatistics | Yale School of Public Health

Chronic Disease Epidemiology Department | Yale School of Public Health

Yale University is an Affirmative Action/Equal Opportunity employer. Yale values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected veterans, and underrepresented minorities.

Postdoctoral Associate - Cancer Survivorship and Tobacco Prevention and Cessation Among Survivors

Posting Date: April 4, 2024

A full-time Postdoctoral Associate position is available within the Yale School of Nursing to assist with the project implementation and closely work with Dr. Hermine Poghosyan.  This is a one-year position with a potential to extend for another year and with a start date; July 1^st, 2024. 

We are seeking a highly motivated and creative Postdoctoral Associate with a strong research background to participate as a professional team member and contribute to ongoing research projects in cancer health disparities, tobacco control and cessation. We are seeking scholars with research interests in cancer health disparities, cancer survivorship, lung cancer screening, and tobacco prevention and cessation among cancer survivors.  In this position, the scholar will be encouraged to conduct mentored and independent research with an emphasis on study inception, manuscript writing, and applying for grants and will also have opportunities to further develop their skills as an independent researcher under the mentorship of Dr. Poghosyan.

Responsibilities include:

• Assisting the research team in handling data produced from quantitative and qualitative approaches
• Creating analytic databases
• Developing analytical models under the guidance of the Investigators and the Biostatistician
• Providing support with literature reviews, data analysis, and dissemination of study findings through publications and presentations
• Leading and collaborating on peer-reviewed manuscript publications
• Maintaining IRB compliance and updating IRB protocols as necessary, and
• Performing other duties as assigned. 
• Collaborating proficiently and communicating effectively with colleagues and management teams
• Being able to design and perform hands on experiments and maintain detailed documentation

Qualifications:

• Must have a PhD in a field applicable to cancer research and associated experience in a health-related area such as public health, nursing, psychology, health policy, social or behavioral sciences, or another relevant field. 
• All requirements of the doctoral degree must be completed before the position start date. 
• Recent PhD graduates and candidates with prior postdoctoral experience are both appropriate.
• Primary research interests should be in the areas of cancer health disparities; cancer survivorship; lung cancer screening behavior; tobacco prevention and cessation among cancer survivors.
• Have a high level of pre-doctoral publication activity
• Have excellent analytic and writing skills and demonstrated potential of scholarly research including content-relevant peer-reviewed publications.
• Knowledge of using statistical software, Stata.
• Be able to interpret statistical output and work independently as well as collaboratively

Preferred Education, Experience and Skills: 

• A PhD in Nursing is preferred.
• Strong data analytical skills.
• Experience using and analyzing population-based data.
• Excellent past academic performance evidenced with publications.

Compensation

• Information about salary, benefits, and career development opportunities can be found at https://postdocs.yale.edu/postdocs.

To apply: Please submit a CV, letter of research interests, 3-5 reprints/preprints of publications, and the names and contact information of three individual references to: Dr. Hermine Poghosyan (Hermine.Poghosyan@yale.edu) AND Cindy DeCoste, Research Project Coordinator (Cindy.DeCoste@yale.edu)

Yale University is an Affirmative Action/Equal Opportunity Employer and values diversity among its students, faculty, and staff.  We welcome applications from women, persons with disabilities, underrepresented minority groups, and protected veterans.

Postdoctoral Associate – Yale Imaging and Psychopharmacology Lab

The Yale Imaging and Psychopharmacology (YIP) Lab at Yale University School of Medicine (PI: Dr. Sarah Yip) is seeking a Postdoctoral Research Associate for a 2-3 year appointment working at the interface between neuroimaging, computational psychiatry and predictive analytics. Appointments are available to start in June 2024 or sooner.

The postdoctoral associate will join a diverse, interdisciplinary team committed to understanding brain-behavior relationships using data from both large-scale data initiatives (e.g., ABCD, UKB) and from curated clinical cohorts (e.g., densely sampled longitudinal fMRI data acquired during treatment for substance use disorders). In addition to developing their own research program, the successful candidate will contribute to multiple NIH funded awards. Our lab is primarily located within Psychiatry and collaborates closely with colleagues in Yale’s Child Study and Magnetic Resonance Research Centers. Thus, there are multiple opportunities for translational research.

Qualifications: PhD, MD or MD/PhD in neuroscience, neuroimaging, statistics, psychology, engineering or a related field is required. Previous experience working with neuroimaging and/or computational modeling is required. Fluency in Python, R or similar strongly preferred.

Compensation: The minimum starting salary for this position is $65,000 and fellows will be provided additional funding for discretionary research expenses, including travel.

Yale School of Medicine has an outstanding track record of mentoring national and international postdoctoral scholars from a wide variety of research and clinical backgrounds. Prior fellows in the Yale Imaging and Psychopharmacology Lab have all gone on to either competitive faculty or industry positions upon completion of their postdoc.

The Yale Imaging and Psychopharmacology Lab is committed to cultivating an inclusive and collaborative multidisciplinary environment. We encourage applications from scholars committed to our mission to build a thriving, collaborative, diverse, and inclusive research community.

To apply: Please e-mail a brief letter of interest describing your current experience, skills, and how your future goals align with this position, along with an up-to-date CV and contact information for three references directly to sarah.yip@yale.edu. Please also feel free to direct informal inquiries about this position to sarah.yip@yale.edu.

Postdoctoral Researcher Position in the Hu lab, Yale University School of Medicine

Overview

Dr. Wei Hu’s laboratory at Yale University School of Medicine is recruiting a postdoctoral researcher to join their interdisciplinary team. The Hu Lab is jointly affiliated with the Department of Immunobiology and the Institute of Biomolecular Design and Discovery (IBDD), working at the interface between immunology and chemical biology. The lab utilizes cutting-edge genetic, biochemical, and chemical tools to explore the biology of regulatory T (Treg) cells across various physiological and pathological contexts, including autoimmunity, cancer, and maternal-fetal immunity. The overarching goal is to unravel the context-specific functions of Treg cells at the cellular and molecular levels and develop strategies to manipulate Treg cells for disease intervention. For detailed information, please visit our lab website: www.weihulab.org.

We welcome scientists from diverse backgrounds to join our growing team. The unique dual affiliation with the Department of Immunobiology and IBDD provides an exceptional opportunity for interaction with two vibrant scientific communities at Yale, enabling you to expand your scientific knowledge and vision. You will benefit from regular interaction and prompt feedback from the principal investigator, as well as the flexibility to explore different research directions based on your expertise and interests. Our commitment to the professional growth of team members includes encouraging applications for fellowships and awards, participation in courses and conferences, and engagement in networking and career development activities.

Responsibilities

In collaboration with the principal investigator and aligned with the lab’s overarching theme, the postdoctoral researcher will:

1. Conduct specific research assignments and develop new projects based on personal interests. This involves conceiving projects, designing research strategies, conducting experiments, analyzing and interpreting data, presenting progress in lab meetings and departmental seminars, and preparing manuscripts for publication.
2. Provide technical and scientific expertise to assist and advise other lab members.
3. Assist the PI in laboratory management and contribute to the development of funding proposals.

Requirements

1. Hold a Ph.D. in Biomedical Sciences, Chemistry, or a related field at the time of hiring. A strong background in reproductive biology, functional genomics, chemical biology, or mouse genetics is highly desirable.
2. Demonstrate a passion for scientific discovery, possess the ability to work independently, and be willing to collaborate with team members.

Salary and Benefits

The salary aligns with the compensation guidelines for postdoctoral researchers at Yale University. The University provides health plans, paid leave, parenting leave, and additional benefits. For more details, please refer to the following links:

Compensation: https://postdocs.yale.edu/policies/compensation

Benefits: https://postdocs.yale.edu/applicants/yale-benefit-summary

How to Apply

Please submit a cover letter, curriculum vitae, and contact information for 2-3 references to wei.hu.wh447@yale.edu. The review of applications will commence immediately, with interviews scheduled for highly rated candidates. The hiring process will continue until the positions are filled.

Postdoctoral Positions in Mucosal Immunity and Intestinal Inflammation (Dr. Clara Abraham)

Investigator: Clara Abraham, MD

Mucosal Immunity and Intestinal Inflammation

Yale University, New Haven, CT

POSTDOCTORAL POSITIONS are available for research on mucosal immunity, intestinal immune homeostasis/intestinal inflammation, and innate immunity. 

The laboratory focuses on understanding mechanisms regulating innate immune responses, host pathogen interactions, and immunological pathways regulating mucosal immunity and inflammatory bowel disease (IBD). The current position will involve examination of molecular, cellular and biochemical mechanisms regulating innate cells and pattern recognition pathways, in particular in the context of genes implicated in IBD.  The ability to incorporate computation approaches to biological questions is also beneficial.  Studies incorporate approaches in both primary human immune cells and in vivo mouse intestinal model systems. 

Education and experience:  Candidates must have a PhD or equivalent degree with a strong background in cellular and molecular immunology, biochemistry, and molecular biology.  Experience in examination of intestinal tissues, multiparameter flow cytometry, and bioinformatics/computational biology is desired. 

Please send curriculum vitae, three names of reference and a one-page summary of research background and interests to Clara Abraham, M.D. (Clara.Abraham@yale.edu)

Yale University is an Affirmative Action/Equal Opportunity Employer.

Postdoctoral position in lipid biology and mass spectrometry in the Zhao Lab at Yale University

We are seeking a postdoctoral fellow to join the laboratory of Dr. Xiaoai Zhao in the Department of Comparative Medicine at Yale University. Zhao lab’s main focus is on the funtional investigation of complex lipids in the context of aging and diseases. Questions that the Zhao lab are interested in include: how do membrane lipids affect cellular function and organismal health during aging and age-related pathologies, what are the organelle-specific lipid contribution in biological processes, and what is the role of complex lipid species in systems metabolism. We use a combination of molecular biology, biochemistry and mass spectrometry in cell and animal models to address these questions. For more information, please visit www.zhaolabyale.com. Interested applicants please send a brief statement of interest and curriculum vitae with contact information for three references to the PI at xiaoai.zhao@yale.edu.

Qualifications:

The successful candidate is expected to develop and apply innovative untargeted lipidomic studies using liquid chromatography mass spectrometry (LS-MS/MS) approaches on a latest Orbitrap MS platform from Thermo. The successful candidate will have completed or will soon complete their Ph.D. degree and should have extensive experience in maintaining and troubleshooting high-resolution MS instruments, particularly orbitrap mass spectrometers. However, substantial prior experiences with other mass spectrometers will also be considered. Hands-on experience in sample preparation and data analysis is preferred. Candidates must have excellent verbal and written communication skills, a strong track record of publications, and the ability to thrive in a dynamic environment with a commitment to excellence.

Opportunities and Benefits:

The candidate will lead research project on the new frontier of functional lipid research in the context of aging and systems metabolism. The Zhao lab is also part of a diverse and vibrant scientific community in the Department of Comparative Medicine and Yale Center for Molecular and Systems Metabolism. This position offers unique opportunity to interact with and learn from labs with broad expertise in metabolism, aging and immunology research. The candidate will also play a pivotal role in the development and shaping of the new Zhao Lab with opportunities to mentor graduate and undergraduate students.

Postdoc compensation and benefits will be according to Yale policies. More information about salaries and other resources can be found at https://postdocs.yale.edu/postdocs.

Join the VACS team!

The Veterans Aging Cohort Study (VACS) team is seeking a Postdoctoral Associate in Pharmacoepidemiology who will be responsible for conducting NIH- and FDA-funded mentored research, focusing primarily, but not exclusively, on deriving real-world evidence on the safety of prescription stimulants among patients with attention deficit hyperactivity disorder (ADHD), and effectiveness of repurposed medications to treat alcohol use disorder in people with and without HIV. More details on the aims and objectives of these grants found below.

The Postdoctoral Associate will join a multi-site, multidisciplinary research team, and be mentored primarily by Dr Christopher Rentsch, PhD, with the opportunity to collaborate with the wider VACS team and external partners through its infrastructure of Cores and Workgroups to acquire experience and knowledge outside of their primarily responsibilities.

The Postdoctoral Associate will be encouraged to articulate research questions of clinical, population health, and mechanistic importance, design research projects, develop detailed analytic plans, perform analyses, interpret results, effectively communicate results orally and in writing, lead and submit results for peer-reviewed publication, and disseminate findings at national and international conferences. 

The ideal candidate will be self-motivated and collaborative, have strong epidemiological skills with some experience using complex, large-scale data (e.g., electronic health records) and a passion for deriving high-quality real-world evidence on medication safety/effectiveness, ideally in the field of addiction.

Responsibilities

• Lead and assist in designing, conducting, and interpreting epidemiological and pharmacoepidemiological research
• Extract and clean very large sources of electronic health records and other routinely-collected data
• Lead and assist with the preparation of abstracts and presentations at national and international scientific meetings and manuscripts for publication, including as lead author 
• Manage elements of larger grants, ensuring compliance with good practice in relation to the conduct of research, and institutional ethics policies
• Undertake high quality research and scholarship, including contributing to drafting major grant proposals and/or leading on drafting smaller grant proposals
• Other duties and responsibilities as assigned or directed by the supervisors, including, but not limited to, travel and attendance of and participation in training and data access activities required for this role

Required Knowledge, Skills and Abilities

• Experience of performing epidemiological or statistical analyses
• Experience extracting and/or analyzing large-scale health datasets, including those derived from electronic health records or other routinely-collected data
• Previous contributions to written output, preferably peer-reviewed
• Proven ability to work independently, as well as collaboratively as part of a research team, and proven ability to meet research deadlines
• Evidence of excellent interpersonal skills, including the ability to communicate effectively both orally and in writing
• Evidence of good organizational skills, including effective time management
• Proficiency in SAS, SQL, or other programming languages

Preferred Knowledge, Skills, and Abilities

• 1-2 years prior post-doctoral experience are preferred but not required
• Some experience of contributing to research grant applications
• Some experience using propensity score approaches, including propensity score matching and/or inverse probability of treatment weighting
• Some knowledge of addiction treatment
• A strong interest and willingness to learn these preferred skills will be reviewed favorably 

This position is jointly funded by NIH and FDA grants and available for a full time (100% FTE) one-year appointment with the possibility of extension upon mutual agreement and availability of funds. Candidates interested in this opportunity are invited to email Dr Christopher Rentsch (christopher.rentsch@yale.edu) with questions, or to apply, with a single PDF including:

1. Cover letter of up to 2 pages detailing previous research experience, interests, and career goals
2. Names and contact information of 2-3 academic references
3. CV

About the projects

FDA funding

The overall aim of this grant is to elucidate current patterns of prescription stimulant receipt and improve our understanding of potential harms associated with these medications. To achieve this aim, these analyses will: 1) characterize patterns of and identify factors associated with receipt of prescription stimulant medication; 2) develop and validate the accuracy of algorithms used to identify patients with ADHD, a key indication of prescription stimulant use, in electronic health record data, and stimulant use disorder codes; and 3) among patients with ADHD, to examine the association between receipt of prescription stimulants and incident addiction, cardiovascular-related health outcomes, and neuropsychiatric outcomes.

NIH funding

The overall aim of this grant is to investigate potential repurposing of medications for alcohol use disorders to provide health benefits in people living with HIV. These analyses will assess whether each medication under investigation is associated with: 1) improvements in direct HIV-related biomarkers, i.e. decrease in HIV RNA levels and/or increase in CD4 count, 2) improved retention on ART, 3) improvement in liver function as measured by clinically relevant biomarkers of liver damage and function; 4) improvement in physical health and physiological frailty; and 5) reduction in pain level.

About VACS

The Veterans Aging Cohort Study (VACS) is a well-established, international, collaborative network of epidemiological, statistical, and clinical experts, with an exceptional track record of productivity and development of early career researchers, many of whom have transitioned to independent NIH and VA funding. The team are excited to offer this opportunity to develop and apply advanced epidemiologic and statistical methods on large, complex, national cohorts derived from electronic health records (EHR) at the Department of Veterans Affairs (VA). Over the past 25 years, the VACS team have curated and maintained several well-characterized cohorts based on VA data made possible by the national

VA Corporate Data Warehouse. The Warehouse provides access to all VA EHR data, including hospital and outpatient diagnoses (recorded using International Classification of Diseases, Ninth Revision [ICD-9] and Tenth Revision [ICD-10] codes), pharmacy data (i.e., dispensed outpatient and inpatient prescriptions), and laboratory results as well as clinical notes, vital signs (including weight and height), and health factors data (level of alcohol use collected via the AUDIT-C and smoking).

Yale University is an affirmative Acton/Equal Opportunity Employer and welcomes applications from women, persons with disabilities, protected Veterans and member of minority groups. Applications will be accepted until the position is filled.

Postdoctoral Associate Position in Cancer Biology and Epigenetics

Bakhoum Laboratory – Departments of Ophthalmology & Pathology and Yale Cancer Center.

Overview

We are seeking highly motivated and creative postdoctoral candidates to join our team. Our NIH-funded research is focused on understanding the role of epigenetic dysregulation in melanoma progression and metastasis, with an emphasis on identifying therapeutic targets.

Requirements:

We are looking for candidates who are motivated, creative, and capable of independent research as well as collaborative teamwork. A strong background in cell culture techniques and/or mouse modeling is preferred. Computational skills are preferred but not required.

Lab Culture and Environment

Our lab values interdisciplinary collaboration and the clinical application of research findings. Postdoctoral fellows will have opportunities to work with a diverse team, including medical and graduate students, fostering an environment that encourages independence and the development of innovative ideas. We use a range of techniques including next-generation sequencing, single-cell genomics, high-resolution imaging, and mouse modeling. Our research is supported by both federal and private foundation grants. Candidate will have access to state-of-the-art facilities and equipment.

Career Development

The position offers a supportive environment for professional growth, including mentorship, opportunities to participate in international conferences, and guidance in grant writing.

Application Process

To apply, please submit the following to mbakhoumlab@gmail.com with the subject line “Postdoctoral Position Application”:

• A cover letter detailing your interest in the position, research experience, and career goals.
• Your current CV.
• Contact information for three references.

For more information please visit www.bakhoumlab.org

Postdoc Position- Dr. Jennifer A Kim, MD-PhD

The Division of Neurocritical Care in the Department of Neurology at Yale University is inviting applications for a two-to-three-year postdoctoral position with experience in physiologic signal processing (e.g., EEG) and statistical/machine learning methods. The applicant would be joining the lab of Dr. Jennifer A. Kim MD-PhD, which focuses on predicting complications and poor outcomes after acute brain injuries, such as trauma, stroke or brain hemorrhage, using data from multiple diagnostic modalities.

The main goal of the research will be to perform time-series or image processing and apply statistical and machine learning methods for prediction of complications and poor outcomes after acute brain injury. The position will require both the processing of already collected datasets as well as assistance with the ongoing effort of establishing a larger data set of recordings, which may include some practical implementation, execution, storage, and transfer of new data.

Applicant must have a background in signal processing and experience in statistical modeling or machine learning methods. Programming experience in Python, Matlab, and/or R is a prerequisite. Experience with EEG or other brain physiology recordings is an advantage but not required. A candidate with a strong statistical background is desired; experience with machine learning methods including random forest and deep learning methods is an advantage, but not required.

Good oral and written English communication skills, the ability to work both independently and as part of a team, is a prerequisite. Candidates must be self-motivated. Responsibilities will include design, implementation and dissemination of research including data processing, modeling, and drafting manuscripts.

This appointment as a postdoctoral researcher requires academic qualifications at the PhD or MD level, preferably in Neuroscience, Bio/Statistics, Engineering, Computer Science, or related areas. Interest applicants should send their CV to Sara Jasak at sara.jasak@yale.edu

Position:  Postdoctoral Associate

Department:  Genetics

Hiring Faculty:  Dr. Yong-Hui Jiang

The Jiang laboratory in the Genetics and Neuroscience is seeking highly motivated candidates for a postdoctoral position. Interests in the laboratory focus on developing new treatments for neurogenetic and neurodevelopmental disorders using CRISPR somatic genome editing approach. In collaborating with Dr. Jiangbing Zhou, Professor of Biochemical Engineering, we have developed a new delivery platform for genome editing mediated by Cas9 and dCas9 in brains and other organs. The new delivery platform, termed Stimuli-responsive Traceless Engineering Platform (STEP) is a non-viral and non-nanoparticle based platform that is capable to penetrate to brain very efficiently.  We have recently received a large NIH grant as a part of Phase 2 of NIH Somatic Genome Editing Consortium. The candidate is expected to develop and test a CRISPR/Cas9 editing based treatment for neurogenetic diseases of interests in mouse model as well as in patient derived IPSC and brain organoids.  

Applicants should be highly motivated with experience in molecular biology, neurological techniques, and mouse study. Of particular interest are candidates with research experience neurogenetic disease mouse models.  The candidate must have a recent PhD or MD/PhD degree in a relevant field with a proven track record of scientific productivity including at least one first author publication in a peer-reviewed journal. Excellent written and oral communication skills are expected. The candidate will be expected to work independently in the design and execution of experiments with guidance from the principal investigator. As projects in the laboratory are often highly collaborative, the candidate should be able to work effectively and enthusiastically in a team environment.

Candidates should send a Curriculum Vitae, a statement of research interests and career goals, and names / contact information for three references to: yong-hui.jiang@yale.edu. Anticipated start date is immediately.

Yale University is an Affirmative Action / Equal Opportunity employer. Yale values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected veterans, and underrepresented minorities.

Summary

• Position: Postdoctoral Associate
• Duties: Project director of the Environmental Performance Index (epi.yale.edu)
• Academic unit: Yale Center for Environmental Law & Policy (envirocenter.yale.edu)
• Location: New Haven, CT, USA
• Qualifications: Ph.D. in Environmental Science, Quantitative Social Science, Statistics or Data Science, or a similar discipline
• Term: Summer 2024 – Summer 2026
• Application: Cover letter and CV
• Deadline: Review of applications begins February 1, 2024 and continues until filled.

Position

The Yale Center for Environmental Law & Policy (envirocenter.yale.edu) seeks a Postdoctoral Associate to serve as the project director for the Environmental Performance Index (EPI) (epi.yale.edu). The position will span the Summer of 2024 to the Summer of 2026, culminating in the launch of the 2026 EPI report.

The EPI has been a flagship project of the Center for over twenty years, tracking trends in sustainability and highlighting global leaders in environmental health and ecosystem vitality. Policymakers, researchers, media outlets, and non-governmental organizations rely on the EPI’s data-driven insights to identify environmental priorities and implement more effective sustainability policies.

The Postdoctoral Associate will supervise all aspects of the 2026 EPI analyses and report by: (1) mobilizing a team of data partners, researchers, and sustainability experts; (2) engaging with environmental and health ministries in governments around the world; (3) supervising multiple environmental research streams and data analyses; and (4) overseeing the production of a high-quality report. In addition to the Postdoctoral Associates primary responsibilities as EPI director, we also seek an individual who can engage with the Center’s broader environmental policy agenda.

Essential Duties

• Oversee all elements of the production of the 2026 EPI report, including developing innovative environmental indicators, reviewing data sources, performing statistical analyses, and communicating findings in high-quality publications.
• Work closely with the EPI Team, including Yale faculty, student research assistants, and our partners at Columbia University’s Center for International Earth Science Information Network.
• Contact and consult data partners at other institutions, including academic research centers, think tanks, and non-governmental organizations.
• Ensure methodological rigor and scientific accuracy of the EPI through surveying the latest advances in environmental data, refining existing approaches, introducing new metrics, and engaging with sustainability thought leaders in academic and policy institutions.
• Curate and expand a code library in support of the EPI’s environmental data analyses.
• Coördinate day-to-day operations and administration of the EPI, including hiring and supervising student research assistants, developing and tracking budgets, and managing contracts with data partners.
• Lead the writing of the 2026 EPI report, website, policymakers’ summary, and technical appendix.
• Develop and implement a communication strategy for disseminating the results of the 2026 EPI, including event planning for the release, engagement with news outlets and social media, and other opportunities for presenting the project to diverse audiences.
• Answer inquiries from international media, government officials, academic researchers, and members of civil society.
• Work with Professor Dan Esty, other Yale faculty, and research partners to publish scientific findings and policy insights in high-impact peer-reviewed journals.
• Otherwise support the work of the Center, including contributing to fundraising efforts and writing reports and other materials for donors.

Education & Experience

• A Ph.D. in Environmental Science or Quantitative Social Science. Possible fields include Climate Science, Environmental Chemistry, Ecology, Sustainability, Public Health, Statistics, Data Science, Economics, Political Science, and Public Policy.
• Experience with statistical analyses and comfort with data analysis.
• Experience in coding (ideally using R, but also Python, Matlab, or a similar data-oriented language).
• Broad knowledge of environmental science and policy, especially in the areas of climate change, biodiversity, and international sustainable development.

Skills & Abilities

The ideal candidate will possess:

• Excellent research, writing, interpersonal, and communication skills;
• Experience with interdisciplinary research and collaborations;
• Demonstrated leadership and project management experience;
• Ability to work under pressure, meet tight deadlines, and manage multiple pressing responsibilities with minimal supervision.

Schedule & Compensation

This is a full-time position for two years to run Summer 2024 – Summer 2026. The start date is flexible, but we cannot offer a deferral. The position requires working during normal business hours throughout the calendar year with occasional travel. Salary is competitive and includes a benefits package through Yale University.

Application Guidelines

• Review of applications will begin on February 1, 2024 and will continue until the position is filled.
• Please email a cover letter and CV as a single PDF to Meghan.Kircher@yale.edu and sebastian.block@yale.edu with the subject “EPI 2026 Post Doc Application”. If your email does not have that in the subject, your application may not get reviewed.
  • Letters may be addressed to Prof. Dan Esty, Yale Center for Environmental Law & Policy, 195 Prospect Street, New Haven, CT 06511.
  • Cover letters should address qualifications for this position rather than summaries of research and publications.
• If invited, candidates may be asked for additional materials, including writing samples and references.

Postdoctoral Associate Position in Social and Behavioral Sciences

Location: Yale School of Public Health

Position Type: Full-time, Postdoctoral Fellowship

Length of position: Renewed annually for up to three years

Start Date: February 5, 2024

Salary Range: $65,000 - $68,000

The Society, Connectedness, and Health (SOCAH) Group at Yale School of Public Health is growing as an important leader in research and solutions to help people in organizations and communities socially connect in ways that increase health and prosperity in multiple areas of life. We are seeking a diligent, hungry, highly motivated, and qualified Postdoctoral Research Associate to join our dynamic research team. This position is based on a newly funded project that focuses on advancing our understanding of the causal impact of neighborhood and individual social connectedness on mental health, as well as other health outcomes, among Black adults in the United States. The Postdoctoral Associate will use: 1) data from the Midlife in the United States (MIDUS) Series, which includes longitudinal and cross-sectional data on over 500 Black adults who reside in Milwaukee, WI; and 2) census-tract spatial identifiers linked to each participant, which will be used as a proxy for neighborhoods. Methodological approaches that will be used in this study include longitudinal analyses, geo-spatial analysis, multilevel analyses, mediation analyses, and qualitative research design and analysis. The Postdoctoral Associate will be at Yale and will collaborate with researchers across several institutions (including Villanova, University of Maryland, Michigan State, The George Washington University). The Postdoctoral Associate will be expected to lead several data management and statistical analyses, writing, and submitting manuscripts for publication. The Postdoctoral Associate will benefit from mentorship on academic advancement (e.g., on writing and winning a K01), have opportunities to write and submit NIH grants, and participate in multiple professional development trainings and opportunities (e.g., developing public speaking skills, attend writing retreats, presenting research from the project at national or international conferences). Review of applications will begin immediately and continue until a qualified candidate is hired. The position may be hybrid (80%) in person at Yale in New Haven with flexibility in schedules including workdays.

Key Responsibilities:

1. Oversee, conduct, and assist with systematic literature reviews of epidemiologic studies on social connectedness and health outcomes among Black people. In addition to conducting and publishing systematic or scoping reviews, the Postdoctoral Associate should develop a system to stay current and abreast of the latest developments in social connectedness and health research to integrate new knowledge into the projects and prepare for new projects.
2. Conduct in-depth research on the effects of social connectedness and mental health outcomes using advanced longitudinal, multilevel, mediation, and spatial epidemiology methods. Prepare and analyze longitudinal datasets for analyses aimed at identifying trends, associations, and potential causal relationships, and identify mediating mechanisms between social connectedness and mental health outcomes.
3. Identify other relevant datasets or collaborate with other researchers who have related datasets that allow for replication and expansion of our primary analyses.
4. Organize and manage complex datasets from the Census bureau, and other independent sources that can be linked to the MIDUS datasets while ensuring data quality and integrity. Merge geographic and other spatial- datasets on social, built, and other environmental variables with individual-level data in the MIDUS. Implement data cleaning and preprocessing techniques as needed.
5. Apply advanced statistical techniques to analyze longitudinal data, hierarchical data such as mixed-effects models, survival analysis, and geospatial analysis to obtain Census-tract level data and perform Bayesian spatial analyses, including Small Area Estimation (SAE) techniques to obtain estimates of the variables for each participant in the dataset.
6. Interpret and communicate results effectively in various formats, including Op-Eds, and blog posts on the SOCAH website and/or social media pages.
7. Assist with developing qualitative research protocols, which includes developing the interview guide, working with other team members to conduct interviews, code, and verify transcribed data, and assist with qualitative data analysis in NVivo or related software.
8. Prepare manuscripts (as first author and second or middle author) for publication in peer-reviewed journals and present research findings at conferences and seminars.
9. Collaborate efficiently and effectively with multidisciplinary teams of researchers, epidemiologists, leadership at community-based organizations, community residents, health geographers, biostatisticians, and public health experts. Examples of collaboration includes organizing communications (e.g., zoom, call, emails) with group members to complete manuscripts on time, to facilitate dissemination of results, obtaining and addressing feedback in a respectful way that centers inclusivity and equity.
10. Provide mentorship and guidance to junior researchers, masters students, and doctoral students who work on the project. Collaboration may include overseeing manuscript writing where you are the lead or second author.

Qualifications:

• Ph.D or Dr.PH in Epidemiology, Public Health, Health Geography, Sociomedical Sciences, Sociology, or a related field with experience working in research examining health disparities, social connectedness, social capital, and related constructs in association with mental health variables  
• A strong background obtaining from multiple sources, wrangling, creating new variables from spatial estimation techniques, and merging geo-spatial data products is essential.
• Experience with or interest in geospatial/spatial epidemiology analysis (Desired)
• Demonstrated expertise in advanced epidemiological methods, including but not limited to longitudinal analysis, survival analysis, multilevel/mixed-effects modeling, and causal inference methods such as mediation analyses, merging nested data, obtaining, and building databases from multiple sources (e.g., Policy Map, American Fact Finder, ESRI Business Analyst)
• Advanced proficiency in R (Required), STATA (Required), and Mplus (Desired) statistical software (as demonstrated by papers published where you used this software)
• Strong analytical and problem-solving skills, with the ability to work with large and complex datasets.
•  Preference will be given to applicants who demonstrate cross-disciplinary and collaborative approaches to the application of social sciences, epidemiology and community-engaged participatory methods.
• Excellent communication skills, both written and oral, for presenting research findings and collaborating effectively with team members and stakeholders.
• A track record of scholarly publications in peer-reviewed journals is a plus.

Application Process:

Please apply online: http://apply.interfolio.com/139067

Interested candidates should submit the following application materials:

1. Cover letter (2-pages max) outlining your doctoral research, your interest in the lab, why you qualify for the position, what unique strengths you bring, and your plans after the position ends.
2. Brief letter (up to 1 page) that describes your positionality in the world, your core values, and commitment health equity, and transforming the lives of marginalized peoples and communities.
3. Curriculum vitae (CV) which shows a list of publications and prior experience.
4. Reprints of two (2) peer reviewed publications you submitted as a first or 2^nd author
5. Names for two letters of reference, at least one from a previous faculty member that you have published with.

Information on benefits for postdoctoral positions can be found here.

Questions regarding this position should be directed to Dr. Yusuf Ransome at yusuf.ransome@yale.edu.
Please put “Postdoctoral Associate” in the subject of the email. Note, there may be delays in email response.

Yale University is an Affirmative Action/Equal Opportunity Employer. Yale values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected Veterans, and underrepresented minorities.