Postgraduate Positions

Yale University’s Nondiscrimination/Title IX Statements

Postgraduate positions are short term training positions for recent college graduates who seek research experience prior to graduate or medical school. As with postdoctoral positions, most postgraduate trainees find their positions by contacting faculty directly. Several faculty have posted their open positions below.
 
Once you find a position, your Yale department will assist you with the hiring process. The visa application process for international postdocs will be handled by your department and the Yale Office of International Students and Scholars. It often takes several months for a visa to be approved, and you should factor this time into your plans for coming to Yale.
 
Postgraduate position in the Department of Internal Medicine (Section of Pulmonary, Critical Care and Sleep Medicine)
Posting Date: January 14, 2021

A position is available for a full-time trainee (Postgraduate Research Associate) in Dr. Melissa Knauert’s lab for Critical Care Sleep research. This is a full-time, paid position with insurance benefits, available for start on or about July 1, 2021.

Training

Under the supervision of Dr. Knauert, the post-graduate research candidate will train as an assistant research team member for several multifaceted research projects focused on sleep and circadian disruption in the medical intensive care unit. The trainee will learn key clinical investigation skills including project design, implementation, data collection, data analysis, and publication.

Mentoring

 Dr. Knauert will provide overall training supervision and direct mentoring for the trainee. Mentoring to include a 1:1 meeting, formal mentee/mentor agreement, setting of short and long-term goals, scientific development, and career development. Additional informal mentorship from lab members at various training levels (undergraduate through post-doctoral) will enrich the trainees experience.

Education

Qualifications include a bachelor’s degree in a related discipline.  Prior experience in a research is preferred, but not required. The position is for 1 year. This is an ideal position for an enthusiastic, self-motivated, and reliable candidate with interest in clinical research.

Interested applicants should send a resume with cover letter to Carol Barfield, HR Associate (carol.barfield@yale.edu).

Yale Fellowship in Developmental Neuroscience of Autism
Posting Date: January 11, 2021

The Yale Autism Center of Excellence (ACE) and Yale Social and Affective Neuroscience of Autism Program (SANA) will select one or more highly qualified college graduates for research fellowship positions at the Yale Child Study Center (CSC). The Yale CSC is a leading institution for clinical diagnostic services and multidisciplinary research on ASD involving behavioral neuroscience, physiology, neuroimaging, molecular genetics, and treatment. Through extensive interdepartmental collaborations, the SANA Program brings together experts in developmental psychopathology, experimental psychology, statistics, neuroimaging, eye-tracking, psychophysiology, and computational science.

The program is led by Dr. Kasia Chawarska and co-directed by Drs. Suzanne Macari and Kelly Powell. Collaborators include Drs. Joseph Chang (Statistics and Data Science), Todd Constable and Dustin Scheinost (Radiology and Biomedical Imaging), Laura Ment (Pediatrics), as well as Flora Vaccarino, Wendy Silverman, Fred Volkmar and Jamie McPartland (CSC). For more information and a list of recent publications, visit the lab website: https://medicine.yale.edu/lab/chawarska/

Mentorship and Training

The fellow will be directly mentored by Drs. Chawarska and Vernetti and will be involved in a highly active and productive community of clinical research scientists. With research mentorship, the selected applicant will be expected to guide a research project from the point of experiment design through analysis and publication of results. The fellow will also assist in a variety of scientific activities in the lab, including assisting in the preparation of manuscripts and conference presentations, and providing general assistance relevant to the functioning of the lab. The fellowship’s curriculum also includes participation in weekly research meetings, research tutorials and courses, and other didactic experiences at the Yale Child Study Center, School of Medicine and Departments of Psychology and Statistics.

The Postgraduate Associate position is one year in duration with a salary of $35,700.00. Anticipated start date is September 2021 and may start remotely in accordance with Yale University guidance around COVID-19.

Award Details

Sponsor Institution: Yale Child Study Center, Yale University

Program Director: Katarzyna Chawarska

Additional Faculty: Suzanne Macari, Kelly Powell, Angelina Vernetti

U.S. Citizenship: Not Required

Eligibility Requirements

Applicants with experience in design and implementation of behavioral, eye-tracking, and/or psychophysiological studies, as well as a strong background in statistical methods, including linear mixed models and data-driven analytic approaches using packages such as R, SPSS, SAS and/or MATLAB, will be reviewed favorably.

Postgraduate positions are open to those who will have received a bachelor and/or master’s degree before beginning the position, but not doctoral degrees. Please note that this fellowship is not offered concurrently with graduate studies. However, we hope that the fellowship will serve as an important stepping stone towards future graduate studies. For more specific questions, interested applicants should contact Dr. Angelina Vernetti at sanalab@yale.edu.

Application Information

Application includes 1 copy of each of the following items, preferably in pdf format:

•A completed application cover page – all sections are required.

•A CV

•Official transcripts, undergraduate and graduate (if applicable). Transcripts should be sent directly from the institution.

•A 2-page personal statement containing biographic material, relevant experience, and career goals - can be single or double spaced

•Two letters of recommendation that speak directly to the candidate’s potential. Electronic copies of recommendation letters are preferred and must be emailed to sanalab@yale.edu directly from the recommender. Hard copies may be sent by recommenders in signed and sealed envelopes to the address below.

•Please include your full name on EVERY PAGE of the items listed above. Application

Deadline

February 7, 2021, 11:59 pm EST. Electronic applications (with scanned documents and separate letters of recommendation emailed directly from referees) are preferred and can be sent directly to sanalab@yale.edu. Items not sent electronically can be sent to:

Yale Child Study Center

Yale Social and Affective Neurodevelopment of Autism Program

300 George Street, Suite 900

New Haven, CT 06511

Yale Fellowship in Developmental Psychopathology and Social Neuroscience
Posting Date: January 11, 2021

The Yale Autism Center of Excellence (ACE) and Yale Social and Affective Neuroscience of Autism Program (SANA) will select one or more highly qualified college graduates for research fellowship positions at the Yale Child Study Center (CSC). The Yale CSC is a leading institution for clinical diagnostic services and multidisciplinary research on ASD involving behavioral neuroscience, physiology, neuroimaging, molecular genetics, and treatment. Through extensive interdepartmental collaborations, the SANA Program brings together experts in developmental psychopathology, experimental psychology, statistics, neuroimaging, eye-tracking, psychophysiology, and computational science.

Mentorship

The program is led by Dr. Kasia Chawarska and co-directed by Drs. Suzanne Macari and Kelly Powell. Collaborators include Drs. Joseph Chang (Statistics and Data Science), Todd Constable and Dustin Scheinost (Radiology and Biomedical Imaging), Laura Ment (Pediatrics), as well as Flora Vaccarino, Wendy Silverman, Fred Volkmar and Jamie McPartland (CSC). For more information and a list of recent publications, visit the lab website: https://medicine.yale.edu/lab/chawarska/

Training

The fellowship’s curriculum includes participation in the Yale Autism Program’s weekly science meetings, weekly SANA Program meetings, research tutorials and courses, and other didactic experiences at the Yale Child Study Center, School of Medicine, and Departments of Psychology and Statistics. The primary training experience will be in daily activities related to behavioral, psychophysiological, and eye-tracking studies. The lab has many ongoing neuroimaging studies with fetal, neonatal, and school-aged participants. Fellows are typically involved in aspects of each study ranging from design and implementation of novel behavioral, eye-tracking and psychophysiological experiments, data processing and analysis of experimental data to participating directly in subject characterization by conducting structured parent interviews and assessing participants.

Fellows will assist with data entry, data quality control, videotaping and coding of experimental sessions, as well as grant manuscript and conference abstract preparation. Additionally, fellows will be given an opportunity to prepare their own conference abstract from the point of data collection though data analysis and abstract submission. Successful applicants will be directly mentored by the program directors and faculty and involved in a highly active and productive community of clinical research scientists.

The Postgraduate Associate position is one year in duration with a salary of $35,700.00.

Anticipated start date is September 2021 and may start remotely in accordance with Yale University guidance around COVID-19.

Award Details
Sponsor Institution: Yale Child Study Center, Yale University
Program Director: Katarzyna Chawarska
Additional Faculty: Suzanne Macari, Kelly Powell, Angelina Vernetti
U.S. Citizenship: Not Required
 
Eligibility Requirements
The program will give priority to applicants with prior experience in research with clinical populations and/or with infants and young children. Experience with implementation of behavioral, eye-tracking, and psychophysiological studies, as well as in data processing and analysis will be helpful. The applicants must be proficient in MS Word, Excel, PowerPoint, and have familiarity with database environments such as SQL. Familiarity with packages such as R, SPSS, or SAS will be reviewed favorably.
Postgraduate positions are open to those who will have received a bachelor and/or master’s degree before beginning the position, but not doctoral degrees. Please note that this fellowship is not offered concurrently with graduate studies. However, we hope that the fellowship will serve as an important stepping stone towards future graduate studies. For more specific questions, interested applicants should contact Suzanne Macari at sanalab@yale.edu.
 
Application Information
Application includes 1 copy of each of the following items, preferably in pdf format:
•A completed application cover page – all sections are required.
•A CV
•Official transcripts, undergraduate and graduate (if applicable). Transcripts should be sentdirectly from the institution.
•A 2-page personal statement containing biographic material, relevant experience, and careergoals - can be single or double spaced
•Two letters of recommendation that speak directly to the candidate’s potential.Electronic copies of recommendation letters are preferred and must be emailed tosanalab@yale.edu directly from the recommender. Hard copies may be sent byrecommenders in signed and sealed envelopes to the address below.
•Please include your full name on EVERY PAGE of the items listed above.
 
Application Deadline: February 7, 2021, 11:59 pm EST.
 
Electronic applications (with scanned documents and separate letters of recommendation emailed directly from referees) are preferred and can be sent directly to sanalab@yale.edu. Items not sent electronically can be sent to:
Yale Child Study Center
Yale Social and Affective Neurodevelopment of Autism Program
300 George Street, Suite 900
New Haven, CT 06511
Postgraduate position in Ventola Lab at the Yale Child Study Center
Posting Date: January 8, 2021
The Ventola Lab at the Yale Child Study Center and Cogstate is looking to fill two postgraduate (post-baccalaureate) positions associated with studies of brain mechanisms and treatment of neurodevelopmental disorders.
The Yale Child Study Center is a leading institution in autism research. Cogstate is an independent science company that supports clinical trials. The Yale Child Study Center and Cogstate have developed a collaborative partnership to support clinical trials in pediatric and developmental disability populations.
Mentorship
Under Dr. Ventola’s mentorship, selected applicants will be expected guide a predetermined project of research from the point of data collection through analysis and presentation of results. Successful candidates will have a high degree of initiative and independence with strong organizational and interpersonal skills. They must have the ability to work effectively with many types of people across different settings while juggling multiple tasks. Flexibility, endurance, and attention to detail are also essential qualities.
Training
The Yale Child Study Center provides fellows the opportunity to shadow weekly developmental disability clinic rounds, attend Child Study Center Grand Rounds, as well as other departmental Grand Rounds lectures in the School of Medicine in addition to their clinical and research responsibilities. The fellows will be involved in industry-sponsored pharmaceutical trials at Cogstate and gain experience with clinical trial design and methodology, clinician trainings, management of cognitive and behavioral assessments, and statistical approaches.
The fellowship combines elements of experiential learning with supervision, self-directed learning, and shadowing. The primary training experience will be training and experience in Pivotal Response Treatment, an evidence-based treatment for children with ASD. The postgraduate fellow, under the supervision of Dr. Ventola, will hold both clinical and research responsibilities. The fellows will be trained in Pivotal Response Treatment (PRT); an empirically-validated behavioral intervention for children with autism spectrum disorder (ASD). They will then be primary PRT clinicians for children with ASD, under the supervision and mentorship of a licensed psychologist. The fellows will also conduct standardized psychological assessments with children and complete a variety of parent interviews. Lastly, fellows will be involved in direct research within the laboratory using fMRI, EEG, and eye-tracking measures.
 
The Postgraduate Associate position is one year in duration with a salary of $35,700.00. Postgraduate positions are open to those who have recently received a bachelor and/or master’s degree, but not doctoral degrees.
 
Anticipated start date is June 2021 and may start remotely in accordance with Yale University guidance around COVID-19.
 
Eligibility Requirements
BA or BS required. Psychology, Pre-Med, or Neuroscience background required with research experience and experience of working with children.
 
Application Information
Please submit a letter of interest, resume, a copy of academic transcript, and at least two letters of reference to Pamela Ventola, Ph.D., at pamela.ventola@yale.edu.
 
Review of applications will begin immediately and will continue until the position is filled.
Postgraduate position in the Department of Psychiatry (Taylor Lab)
Posting Date: January 4, 2021

The Taylor lab seeks a postgraduate associate to join our team to help us study decision-making and alcohol use in rodent models. The Taylor lab investigates mechanisms underlying decision-making and addiction using operant conditioning, computational modeling, molecular biology, and fiber photometry approaches. Dr. Thompson’s research within the Taylor lab aims to elucidate the role of environmental influences on complex behaviors such as decision-making and maladaptive alcohol use, including dietary manipulations and the role of the gut microbiome.

Training:

This position will provide extensive hands-on and conceptual training in these areas in addition to opportunities for authorship on scientific publications. As a member of the Taylor lab, you would have the opportunity to participate in the weekly Taylor lab meetings, weekly division-wide lab meetings, and weekly seminars on molecular psychiatry research. The Taylor lab is a part of the Molecular Psychiatry Division of the Department of Psychiatry at Yale School of Medicine, a vibrantly collaborative and educational community that is ideal for early stage investigators to receive training in neuroscience approaches and concepts.

Duties may include performing behavioral experiments, rodent colony management, molecular biology experiments, data handling and analysis, or contributions to manuscripts. We seek a candidate who is available immediately and looking for a one year commitment.

Mentorship:

The successful candidate will work with Dr. Summer Thompson, a postdoctoral scholar in the Taylor lab. Dr. Thompson is a dedicated mentor with a track record of trainees successfully advancing in the careers of their choosing. Dr. Thompson will directly train the successful candidate in technical, presentation, and problem-solving skills related to the position, in addition to providing career guidance and support. The Taylor lab is committed to promoting an inclusive and welcoming environment that fosters the development of the next generation of scientists. As such, we are dedicated to the recruitment and retention of individuals from diverse backgrounds.

Education:

Interested candidates should have an academic or technical background in neuroscience, psychology, or a related field with a bachelor’s degree. However, applicants with alternative backgrounds will be considered. If you are enthusiastic, curious, reliable, organized, and a strong communicator, this position may be a good fit for you. Prior laboratory experience and experience handling rodents, particularly mice, is a plus but not required, as this position is will require daily rodent handling.

Interested candidates should contact Dr. Thompson via email (summer.thompson@yale.edu) with a copy of their curriculum vitae and a brief statement explaining the candidate’s background including any prior laboratory experience, the reason for interest in the position, career goals, and availability timeline.

Postgraduate position in the Department of Neurology ( Pitt Lab)
Posting Date: January 4, 2021

A postgraduate student position is available in the laboratory of Dr. David Pitt, MD, Department of Neurology, Yale School of Medicine. We conduct translational research in multiple sclerosis (MS) with the goal of understanding the mechanisms of MS progression. We work with induced pluripotent stem cell (iPSC)-derived CNS cells from MS patients, human CNS autopsy tissue and advanced imaging methods on MS patients.

Training

The successful candidate will receive training in histological techniques (cutting, processing and immune-histochemical staining of human CNS tissue), histopathological evaluation of multiple sclerosis lesions, highly multiplexed fluorescent imaging including computational analysis, and cell culture techniques related to  iPSC-derived astrocytes/microglia cells.

Mentoring

Direct mentorship from Dr. Pitt and several post-docs in the lab. Mentoring includes one-on-one sessions to evaluate multiple sclerosis lesions histologically, weekly one-on-one meetings to design and troubleshoot experiments, and presentations in lab meeting/journal club.

Education

Bachelor’s degree in a biology-related field. Prior research experience is desirable.

The position is available starting February 1st. If interested, please respond with CV to david.pitt@yale.edu.

Postgraduate position in Molecular, Cellular and Developmental Biology (Breslow lab)
Posting Date: January 3, 2021

David Breslow’s lab, part of the Dept. of Molecular, Cellular and Developmental Biology at Yale University, is seeking a full-time post-graduate researcher to support the development of a research program aimed at understanding the functions of the mammalian primary cilium.

The main focus of our research is the mammalian primary cilium, a micron-scale structure protruding from the surface of almost all cells in the human body. Using a combination of functional screening, microscopy and biochemistry, we are investigating the basic processes by which cilia are assembled, maintained, and disassembled. Areas of particular interest include understanding how the cilium serves as an organizing center for select signaling pathways (e.g. Hedgehog signaling) and dissecting the complex interplay between cilium assembly/disassembly and the cell cycle. Additionally, we have a strong interest in applying new technologies to study cilia, including genome-wide CRISPR-based screening and advanced imaging methods. Together, our studies aim to provide fundamental biological insights, to shed light on the pathogenic mechanisms of cilium-based diseases, and to reveal new strategies for targeting Hedgehog-driven cancers.

Training:

The post-graduate researcher will learn a variety of experimental procedures including CRISPR-based mutagenesis, molecular cloning, culture of mouse and human cell lines, and advanced microscopy techniques. Direct mentorship from the PI, and opportunities to pursue independent research will be provided.

Mentoring:

The post-graduate researcher will work closely with Prof. Breslow and other members of the Breslow lab to gain experience in the design, execution, and analysis of experiments. Mentorship in written and oral communication and opportunities for career development will be provided. This position is an excellent fit for researchers interested in gaining research experience and skills before pursuing a Ph.D. in molecular cell biology or a related field.

Minimum requirements: Bachelor’s degree (completed within the last two years) in a biology-related field with significant laboratory coursework.  Prior research experience, particularly in mammalian cell culture, molecular biology, light microscopy, or biochemistry, is highly desirable. Applicants should be motivated, dependable, and highly organized. Strong communication skills and the ability to work effectively within a research team are essential.

The position is available from May 1, 2021 and a start date before July 1, 2021 is strongly preferred. If interested, please send a cover letter briefly summarizing your research experience and goals, a CV, and contact information for 2-3 references to david.breslow@yale.edu

For more information, visit: http://breslowlab.yale.edu

Postgraduate position in Sukhodolsky Lab in the Yale Child Study Center
Posting Date: December 14, 2020

The Sukhodolsky lab at the Yale Child Study Center is looking to fill two postgraduate (post-baccalaureate) positions associated with studies of brain mechanisms and treatment of neurodevelopmental disorders. One position will be primarily responsible for studies of behavioral interventions for children with autism spectrum disorder, including cognitive behavioral therapy for anxiety and behavioral therapy for irritability and the second will be primarily responsible for coordinating a multisite, longitudinal neurogenetics study of gender differences in autism.

Training

Both positions will have responsibilities in study coordination, running subjects through clinical assessments, collecting fMRI and EEG data, and managing study databases. In addition to current studies with children on the autism spectrum, the Sukhodolsky lab conducts clinical research in the areas of childhood disruptive behavior disorders, ADHD, Tourette Syndrome and OCD. Postgraduate associates will gain deep knowledge of developmental psychopathology and will benefit from a collaborative environment by contributing to all projects.

Mentoring

The postgraduate associates will be trained in a variety of aspects of clinical research and will gain experience in childhood neurodevelopmental disorders. The positions include the following learning opportunities:

  1. Learn about autism and developmental psychopathology and behavioral treatments for anxiety and irritability in autism. Train on how to guide children and families through clinical studies of behavioral therapy. Learn to administer, score and interpret measures of social behavior, anxiety and neurocognitive functioning to children and adolescents.
  2. Become familiar with functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). These techniques are used in the Sukhodolsky Lab to examine brain mechanisms of response to cognitive-behavior therapy in youth and gender differences in autism. Postgraduate associates will learn the importance of the interface with families during all parts of the research process.
  3. Learn about behavioral, neuropsychological and neuroimaging research conducted with children with neurodevelopmental disorders. Postgraduate associates will have an opportunity to learn about psychological assessments of symptoms, intelligence, and adaptive functioning as well as neurocognitive tasks for evaluating brain mechanisms of cognitive and emotional functioning.
  4. Additional learning opportunities include: attending weekly grand rounds devoted to various topics in child and adolescent psychology and psychiatry; aiding in preparation and possibly co-author manuscripts based on research studies conducted; learning about data management and analysis procedures in clinical trials.

The Postgraduate Associate position is one year in duration with a salary of $35,700.00.   Postgraduate positions are open to those who have recently received a bachelor and/or master’s degree, but not doctoral degrees. Anticipated start date is June 2021 and may start remotely in accordance with Yale University guidance around COVID-19.

Education

BA or BS required. Psychology, Pre-Med, or Neuroscience background required with research experience and experience of working with children. Please submit a letter of interest, resume, a copy of academic transcript, and at least two letters of reference to Denis Sukhodolsky, Ph.D., at Denis.Sukhodolsky@yale.edu.  Review of applications will begin in immediately and will continue until the position is filled.

Postgraduate position in the Müschen Laboratory (Oncogenic Signaling)
Posting Date: December 11, 2020

Center of Molecular and Cellular Oncology, Yale School of Medicine

Over the past 12 years, our laboratory has developed a multidisciplinary research program focused on oncogenic signaling and clonal evolution in B-cells. Antibody-producing B-cells are under intense selective pressure to remove autoreactive and pre-malignant clones, yet autoimmune disorders and B-cell malignancies such as leukemia are very common and often incurable diseases. By understanding the mechanisms of B-cell selection, we are able to explore new therapeutic targets in B-cell tumors. Our scientific discoveries are driven by the desire to create a stimulating academic environment where we focus on rigorous, collaborative and innovative science. In the laboratory, we promote a culture of inclusivity, mentoring our trainees’ scientific growth, and striving to make science accessible to everyone.

Training

We are seeking a postgraduate associate interested in gaining experience in the fields of cancer genomics, systems biology and bioinformatics. The successful candidate will work closely with the postdoctoral bioinformatician to learn analysis of varied high throughput sequencing experiments performed in our laboratory covering proteomics, transcriptomics, and genomics as well as analysis of public datasets. This includes interpreting, recording, and summarizing analysis results for communication to other lab members as well as parsing and curating large datasets for storage and use in downstream analysis.

Mentoring

Under the guidance of Dr. Markus Müschen and the postdoctoral bioinformatician, the candidate will have the opportunity to contribute to the ongoing research projects and take part in high impact publications. Depending on the interests of the applicant a joint wet-lab/bioinformatics position would also be possible.

Some of our research projects include:

Harnessing negative selection to treat B-cell tumors. We developed the paradigm that, unlike other cancer-types, B-cell malignancies can be treated by targeted engagement of negative selection. This can be achieved by pharmacological kinase-hyperactivation to mimic excessive signaling-strength from autoreactive B-cell receptors. Targeted cancer-therapy is traditionally focused on kinase-inhibitors to suppress oncogenic signaling. Our concept of kinase-hyperactivation effectively represents the opposite (Chen Nature 2015; Shojaee Nature Med 2016).

Metabolic gatekeeper paradigm. We pursue the new concept that negative selection is predicated on a B-lymphoid transcriptional program to restrict glucose-uptake and energy-abundance, a mechanism we termed ‘metabolic gatekeeper’. Given that pathogenic B-cells have higher energy-demands than their normal counterparts, we hypothesize that mechanisms to limit energy-supply safeguard against autoimmune disease and B-cell malignancies by setting low thresholds for elimination based on energy-stress (Chan Nature 2017; Xiao Cell 2018).

Mechanisms of energy-conservation in B-cells. We previously established that B-cells develop under conditions of chronic energy-depletion. Studying how B-cells survive acute surges of energy-consumption during physiological B-cell activation, we discovered a novel dependent feedback-mechanism of energy metabolism. One of these mechanisms involves a well-known cytokine receptor-chain. Ongoing studies illuminate how this receptor has been repurposed in B-cells to function as a dynamic feedback-regulator of energy expenditure (Chan Nature 2020; Lee Nature 2020).

Why do B-cells have the smallest cytoplasm and fewest mitochondria of all cells? Our laboratory has recently developed conceptual models to identify factors that orchestrate the unique morphology of B-cells, to examine why maintenance of a small cell-size is essential for B-cell survival and whether engineered B-cells that harbor more and larger mitochondria are prone to autoimmunity and B-cell tumors (Müschen Nature Rev Cancer 2018; Müschen Nature Rev Immunol 2019).

Education

Candidate must have a Bachelor’s or Master’s degree in biological or computational science and have a track record of experience with bioinformatics - either taught courses or preferably practical experience. The ideal candidate should have a passion for working on challenging research questions in an interdisciplinary team setting, be organized, motivated and have excellent communication and problem-solving skills. Experience in the fields of cancer genomics or hematology is preferred but not required.

Your application should include in one single PDF:

CV, brief motivation statement, coordinates of three scientific mentors (references) sent to Markus Müschen via email (markus.muschen@yale.edu).

Postgraduate position at the Clinical and Translational Research Accelerator
Posting Date: December 8, 2020

A post-graduate research position in clinical and translational research is available in the Department of Pediatrics within the Clinical and Translational Research Accelerator at Yale University. The position is available for one year. The laboratory focuses on improving risk prediction and developing novel biomarkers to assist with clinical decision making and inform clinical trials in children with kidney disease.

Education: Requirements for the position include a BA/BS in the life sciences or completion of the premedical track. Experience with statistics and/or scientific writing is a plus. We seek candidates with a strong desire to contribute to patient-oriented research and obtain medical knowledge. Prior experience in a research laboratory or hospital is preferred but not required. Candidates should be motivated, enthusiastic, and organized.

Training: The candidate will have the opportunity to obtain clinical research experience, interact with patients and healthcare professionals, and work closely with clinical physicians. There is also the opportunity to participate in manuscript publication.

Mentoring: The candidate will have extensive mentoring in clinical and translational research as a part of this position. Weekly mentorship meetings will take place to discuss study design, conducting research, statistical analysis, interpretation of results, and manuscript preparation. Additionally, frequent interactions with physician-scientists, participation in bi-weekly conferences dedicated to methodological issues in ongoing and future research, and frank collaboration on projects within our community make this an ideal environment in which to train while gaining research experience.

Our lab is composed of a multi-disciplinary team of physicians, nurses, research fellows, and study coordinators. Further details about the Clinical and Translational Research Accelerator is available at https://medicine.yale.edu/intmed/ctra/

Review of applications will begin immediately and will continue until the position is filled.  To apply, please submit a cover letter in the body of an email and CV/references as attachments to jason.greenberg@yale.edu

Postgraduate position in Epilepsy Research in Department of Neurosurgery (de Lanerolle Lab)
Posting Date: November 16, 2020

The Epilepsy Research laboratory is looking to hire a Postgraduate Associate to participate in research on the molecular neuropathology of animal and human temporal lobe seizure foci. This position is in the laboratory of Dr. Nihal de Lanerolle. This can be a full or part-time paid position initially for one year.

Training

The postgraduate research associate will train in research methods under the supervision of Dr. de Lanerolle and the senior Research Assistant. The associate will participate in studies on animal models of hyperthermic (fever) seizures to investigate changes in molecular and gene expression during epileptogenesis and chronic spontaneous seizures.

These studies will involve training in the development of the seizure model, animal surgery for implantation of electrodes of detecting neural activity and techniques for video-EEG recording and analysis. Additionally, techniques for extraction of proteins, DNA, RNA and immunoblotting will be used. Also, immunohistochemistry. There will also be opportunities for interacting with members of the clinical epilepsy program and human tissue studies.

Mentoring

The candidate will be mentored by Dr. de Lanerolle to learn proper laboratory procedures, experimental design and planning and writing research reports for publication.

Education

Qualifications required include a Bachelor’s or Master’s degree with expertise in biochemistry & molecular biology. Some familiarity with immunology would be preferred but not essential. Must be comfortable working with rodents. Candidates should be motivated, organized, responsible and enthusiastic.

Review of applications will begin immediately and will continue until the position is filled.  To apply, please submit a cover letter in the body of an email, a CV and names of referees as attachments to nihal.delanerolle@yale.edu.

Postgraduate Associate Position in YSPH, Department of Epidemiology of Microbial Diseases (Dr. Albert Ko)
Posting Date: November 12, 2020

Yale School of Public Health, Department of Epidemiology of Microbial Diseases, is looking to hire a Postgraduate Associate. We are providing an opportunity for a post baccalaureate graduate to perform research on natural history of SARS-CoV-2 infection, engage in cohort studies of people who have been infected with SARS-CoV-2 and evaluate outcomes of reinfection and persistent viral shedding in this cohort. This is a full-time position with benefits.

Training

Under the supervision of Dr. Albert Ko and Wade Schulz, the Postgraduate Associate will receive specific training in performing cohort investigations which includes recruiting participants, implementing follow-up protocols and monitoring the cohort for clinical and virologic outcomes.

Mentoring

The Postgraduate Associate will be mentored by Drs. Ko and Schulz. The research candidate will be enrolling participants by informed consent, performing interviews, entering clinical research data and assisting with data analyses.

Education

Qualifications include a Bachelor’s Degree in disciplines and tracks related to clinical research and public health (health sciences, biology and other exact sciences, premed courses).  Prior experience in research is preferred, but not required. As well, experience with clinical research, database procedures and use of statistical software is preferred but not required.  The position requires a one-year commitment. This is an ideal position for an enthusiastic, self-motivated and reliable candidate with interest in clinical research, public health, and infectious diseases.

Interested applicants should send a cover letter briefly describing career goals, interest in this position and research background along with a resume and contact information for three references to Dava Flowers-Poole at dava.flowers@yale.edu.

Postgraduate position in the Section of Pulmonary, Critical Care and Sleep Medicine (Takyar Lab)
Posting Date: October 26, 2020

Yale School of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine (PCCSM), is looking to hire a highly motivated Postgraduate Associate to drive innovative research projects forward in the laboratory of Dr. Takyar. This is a full-time, paid position with insurance benefits.

Training

Under the supervision of Dr. Takyar, the post-graduate research candidate will train to work as an assistant research team member and participate in molecular investigations on the origins of lung cancer and severe lung inflammation in disease such as asthma and COVID-19. The candidate will have interaction and exposure with physicians and researchers in several institutes at Yale, and receive hands on experience in RNA biochemistry and cellular and animal modeling. The funded projects are related to drug discovery and pave the way for critical thinking in biologic target identification and design of diagnostic and therapeutic interventions.

Mentoring

Candidate will be mentored by myself and senior research coordinator to learn proper laboratory techniques associate with study protocol and will receive guidance in identifying an independent research project.  

Education

Qualifications include a Bachelor’s Degree in a related discipline (biochemistry, molecular biology, immunology, premed).  Prior experience in a research is preferred, but not required. The position requires a one-year commitment. This is an ideal position for an enthusiastic, self-motivated and reliable candidate with interest in molecular biology, RNA biochemistry, cancer, asthma, and lung inflammation.

Postgraduate Associate at the Clinical and Translational Research Accelerator
Posting Date: October 23, 2020

A postgraduate research position in clinical and translational research is available for a one year period in the Department of Internal Medicine within the Clinical and Translational Research Accelerator starting May/June 2021. The lab has several ongoing clinical research studies focusing on developing novel biomarkers related to various kidney pathologies. The position provides direct patient interaction and an introduction to patient-oriented biomedical research. This position will provide training in learning clinical research methodologies including good clinical practices (GCP) and NIH/FDA guidelines. Postgraduate will also have the opportunity to interact with both patients and healthcare professionals in hospital, clinic and laboratory settings. Responsibilities may include, but are not limited to: assistance in clinical data and quality management, consenting/interacting with patients, developing presentations, biospecimen processing, and reporting at team meetings.

Requirements for the position include BA/BS in the life sciences or completion of the pre-medical track. Prior experience in a research laboratory or hospital is preferred but not required. We seek candidates with a strong desire to contribute to patient-oriented research and obtain medical knowledge. The associate will have the opportunity to obtain clinical research experience, interact with patients and healthcare professionals, and work closely with clinical physicians. There is also an opportunity to participate in manuscript publication and to lead sub-studies. 

The lab is composed of a great group of physicians, research fellows, nurses, and study coordinators. Further details about the Program of Applied Translational Research is available at https://medicine.yale.edu/intmed/ctra/

Review of applications will begin immediately and will continue until the position is filled.  To apply, please submit a cover letter in the body of an email and CV/references as attachments to frida.calderon@yale.edu

Postgraduate position in the Department of Dermatology ( Myung Lab)
Posting Date: October 20, 2020

Peggy Myung, MD, PhD, is seeking a post-graduate student for a Postgraduate Associate position in her laboratory in the Department of Dermatology, Yale School of Medicine. The ideal candidate has a strong background in Biological or Chemical Sciences but has not yet received a doctoral degree and is seeking advanced scientific training for one year.

Mentoring/Education

The Postgraduate Associate will also be mentored by the PI and lab members on how to write scientifically, present scientific data, critically review scientific articles, and how to design experiments. This will also entail giving the trainee the opportunity to present his/her data at weekly lab meetings and at national/international conferences. The overall goal is to learn how to design and perform scientific experiments that can be used to develop his/her skills for a future career in science and/or medicine. These career development opportunities (e.g. scientific writing and public speaking skills) will be individually tailored to his/her long-term career goals. The ultimate goal is to create an experience that is rewarding and engaging for everyone in the lab and that fosters scientific and professional growth!

Training

This Postgraduate Associate will be trained to perform basic science research that explores the cellular and molecular dynamics that control skin and hair follicle development, adult hair follicle regeneration and hair follicle stem cell regulation, as well as skin tumorigenesis, using novel live imaging and genomic approaches coupled with classical genetic tools. Specifically, the project uses mouse genetic models to trace the cellular and molecular origins of hair follicle progenitors during development as well as during adult regeneration. In this lab, he/she will be trained to become proficient at a broad range of techniques, including mouse husbandry, multi-photon and confocal imaging, molecular biology, single-cell RNA sequencing, in situ hybridization as well as others.  Prior research experience using basic molecular biology or animal models is a plus but not required.

The Postgraduate Associate will have the opportunity to perform/participate in the following:

  1. Assist with mouse colony management, husbandry and genotyping
  2. Chemical, in situ hybridization and immunohistochemical stains of mouse or human tissue followed by visualization using various microscopy techniques including multiphoton microscopy, confocal microscopy, and basic immunofluorescence/brightfield microscopy
  3. Basic molecular biology techniques such as quantitative PCR, and preparation of RNA for bulk and single-cell RNA sequencing
  4. Basic tissue culture techniques using primary skin cells and cell lines
  5. Administration of soluble compounds to mice to analyze genetic effects of specific genes
  6. Use basic software/statistical tools such as Adobe Photoshop, illustrator, Fiji, etc.
  7. Assist with data analysis, interpretation, and generation of figure quality data for publication and/or presentations
  8. Attend intra-mural and extra-mural conferences where he/she can present research data and develop communication/presentation skills
  9. Attend weekly dermatology and/or pathology research in progress conferences as well as weekly lab meetings
  10. Attend one-on-one meetings with the PI to review scientific data/progress and goals and to provide reciprocal constructive feedback

Interested candidates should email a cover letter that briefly describes their personal and career goals as well as their research/scientific background, their CV, and 3 letters of reference to peggy.myung@yale.edu

Postgraduate position in Human Translational Immunology
Posting Date: October 13, 2020

Postgraduate positions for research on the intestinal and placental mucosal immunology  in the laboratory of Liza Konnikova at Yale University.

Research in the Konnikova group is directed at studying the development and maintenance of mucosal immunity at barrier sites such as the intestine and placenta. We are interested in understanding how homeostasis is established and maintained in humans and what goes awry to cause disease such as necrotizing enterocolitis and inflammatory bowel disease in relationship to intestinal health and preterm labor in case of placental biology. We are seeking a motivated, dynamic individual who is interested in applying cell biology, organoid and immunology approaches to understanding fundamental mechanisms governing the establishment and maintenance of human mucosal immunology in health and disease. During this time, the successful applicant will obtain training in immunologic techniques such as FACS and mass cytometry, in vivo models and translational research.

Research Activities - The Post-graduate will use a combination primary cell culture techniques, FACS and imagining modalities to understand the the mechanisms leading to mucosal immunity.

Training - The Post-graduate will receive training in cell biology techniques including cell culture and molecular biology (ie. PCR, next generation sequencing) and immunobiology techniques (ie. FACS, mass cytometry).

Mentoring Plan - The successful candidate will receive daily, hands-on mentoring from members of the Konnikova lab. The candidate will meet with the PI regarding their productivity and interpretation of their data on a weekly basis. Finally, the candidate will be expected to present at lab meetings on a bi-monthly basis.

The candidate will be expected to have a B.A./B.S. in the field of biological or chemical sciences. Some lab experience in cellular and molecular biology or immunology is preferred. Candidates should be a team player, self-motivated, organized, responsible, enthusiastic and eager to learn. For more information on our group, please see our website – www.konnikovalab.com.

Interested applicants should send a brief statement of interest, your work experience and a resume with contact information for three references to the Principal Investigator, Dr. Liza Konnikova (liza.konnikova@yale.edu).

Postgraduate positions for research on the developmental biology, growth and regeneration of the liver are available in the laboratory of Dean Yimlamai
Posting Date: October 7, 2020

Research in the Yimlamai Lab is directed at understanding the drivers of human liver disease, particularly in Pediatric diseases such as biliary atresia and non-alcoholic steatohepatitis. Our focus is in the cell biology of epithelial cells with their microenvironment. We are seeking a motivated, dynamic individual who is interested in applying cell biology, organoid and animal model approaches to understanding fundamental mechanisms in liver biology for eventual application to Pediatric disease. During this time, the successful applicant will obtain training in genetics, in vivo models as well as a range of cell and molecular biology techniques.

Research Activities - The Post-graduate will use a combination of mouse injury models and cell culture techniques to understand the basic mechanisms of liver regeneration.

Training - The Post-graduate will receive training on mouse genetics, cell biology techniques including cell culture and molecular biology (ie. PCR, next generation sequencing) techniques.

Mentoring Plan - The successful candidate will receive daily, hands-on mentoring from members of the Yimlamai lab. The candidate will meet with the PI regarding their productivity and interpretation of their data on a weekly basis.

The candidate will be expected to have a B.A./B.S. in the field of biological sciences, and have some experience in cellular and molecular immunology, biochemistry, or molecular biology. Candidates should be motivated, organized, responsible and enthusiastic. For more information on our group, please see our website – www.liverstemcells.org.

Interested applicants should send a brief statement of interest, your work experience and a resume with contact information for three references to the Principal Investigator, Dr. Dean Yimlamai (dean.yimlamai@yale.edu).

Postgraduate position in the Section of Nephrology (Chang Lab)
Posting Date: September 9, 2020

Yale School of Medicine is seeking a highly motivated Postgraduate Associate to join the laboratory of William Chang MD, PhD. The lab has several ongoing research studies focusing on kidney and vascular tissue engineering.

Training/Mentoring

The Associate will learn how to use microfluidic devices to form microvasculature networks on a chip, and to differentiate kidney organoids from inducible pluripotent stem cells. The associate will work directly with the principal investigator, Dr. Chang.  The Postgraduate Trainee will receive intensive mentorship and training in laboratory research techniques, critical thinking, and problem solving. The Associate will also have an opportunity to participate in manuscript publications, laboratory group meetings, and will gain experience presenting their research.  

Education

Applicants for the position should have a BA/BS in the life sciences, biomedical engineering, or completed a pre-medical track. Prior experience in a research laboratory is preferred but not required.  This is an ideal position for an enthusiastic, self-motivated and reliable candidate with interest in Nephrology and medical research.

Review of applications will begin immediately and will continue until the position is filled.  To apply, please submit a cover letter in the body of an email and CV/references as attachments to Carol Barfield at carol.barfield@yale.edu

Postgraduate position in Reproductive Immunology (Laboratory of Dr. Vikki Abrahams) in the Department of Obstetrics, Gynecology & Reproductive Sciences
Posting Date: September 9, 2020

This is a full time paid 12 month position to work in the laboratory of Dr. Vikki Abrahams, PhD in the Department of Obstetrics, Gynecology & Reproductive Sciences.

The laboratory focuses on understanding the role of innate immune Toll-like receptor and Nod-like receptor family members in placental and maternal-fetal immune responses, and their role in regulating pregnancy outcomes using basic and translational approaches.

Training/Mentoring

The current position will involve basic lab-based research studies examining the effect of antidepressants on placental fetal membrane immunobiology. These studies will utilize a variety of human in vitro models and techniques including tissue and cell culture, Western blot analysis, ELISA and qRT-PCR.

Training and mentoring will be provided for working with lab techniques, and in principles of experimental design, problem solving, and analysis of results. Intellectual and technical contributions will provide opportunities to present data at research meetings and co-authorship on peer-reviewed publications. This is an ideal position for recent graduates interested in strengthening their research experience prior to medical or graduate school.

Education

Applicants should have a BA or BS in a related field. Prior lab-based research experience is preferred. Candidates should be highly organized, self-motivated, hard-working and reliable, with excellent interpersonal and communication skills. Must have good attention to detail and problem-solving skills, be able to multi-task, and be able to perform both independently as well as in a team environment.

Applicants should email: 1) a Curriculum Vitae; 2) contact information for at least two references; 3) a short description of their research background and interests and career goals; and 4) an estimation of their time commitment to Dr. Vikki Abrahams (vikki.abrahams@yale.edu).