Title of the Position: Postgraduate position in the Escobar-Hoyos lab
Department and School: Department of Therapeutic Radiology
Anticipated appointment dates: December 2025
Email/website: natasha.pintomedici@yale.edu and lyanne.delgadocoka@yale.edu https://medicine.yale.edu/lab/escobar-hoyos/.
INTRODUCTION:
Our mission in the Department of Therapeutic Radiology is teaching and research in clinical and translational radiation oncology, radiobiology, and radiological physics. The Escobar-Hoyos lab focuses on uncovering the biology of pancreatic cancer that can ultimately lead to the development of new efficient therapies to treat this devastating malignancy. Our lab is a multidisciplinary environment involving experts with backgrounds spanning oncology, immunology, bioinformatics, drug delivery, and microbiology. Our projects give our trainees access to cutting-edge technology and unique collaboration opportunities across different Yale Departments within the Yale School of Medicine.
POSITION OVERVIEW:
We are looking for a highly motivated individual interested in a provocative interdisciplinary project that aims to create novel therapies against pancreatic cancer employing mechanistic-based studies. Interested applicants should hold a B.S. or B.A., have fundamental expertise in biology chemistry, and be research oriented. The candidate should be self-motivated, enjoy working and collaborating with the other members, and follow the lab philosophy: nurture a science-driven, collaborative, and respectful environment that allows the team to ask and tackle creative and exciting scientific questions.
The competitive candidate will be involved in the following areas:
Qualifications
- Applicants must have a bachelor’s degree in biology, chemistry, biochemistry, microbiology, or a related scientific discipline. Prior research experience is desirable but not required. Applicants must possess strong communication, organization, and data analysis skills.
- We are seeking a candidate who can start by December 2025 and commit to the position for at least 12 months.
Education
This position provides an immersive training experience designed to support the candidate’s long-term educational and professional aspirations in biomedical research, graduate school, or medical school. Through hands-on research and structured mentorship, the trainee will:
- Build a Strong Scientific Foundation
- Develop expertise in cancer biology, RNA biology, immunology, and translational research.
- Gain technical proficiency in molecular and cellular techniques critical for future research.
- Enhance Analytical and Critical Thinking Skills
- Learn to design and interpret experiments that contribute to the understanding of tumor biology.
- Engage in scientific discussions through lab meetings and journal clubs to refine problem-solving abilities.
- Prepare for the Next Career Stage
- Receive personalized mentorship and career guidance, including application support for graduate or medical school.
- Develop a strong research portfolio, with opportunities to contribute to publications and present findings at conferences.
Training
Through this project, the trainee will be exposed to:
- Cell culturing techniques, such as: culturing of cancer cells, immune cells, and generation of isogenic cell lines through virus transduction.
- Molecular biology experiments, such as western blotting, eCLIP and qRT-PCRs.
- Bacterial culturing and cloning.
- In vivo work, such as mice colony maintenance, immunization, and tumor implantation.
Mentoring
- Dr. Escobar-Hoyos will mentor trainees. They will also be exposed to other laboratory members and their projects, providing additional mentorship.
- Candidates will meet weekly with mentors for project updates, career development, and personal growth.
- The laboratory offers lab meetings to improve science-related skills.
- Candidates will be advised and guided through applying to graduate school, medical school, funding opportunities, and conferences.
- Our website, https://medicine.yale.edu/lab/escobar-hoyos/, has more information on the Escobar-Hoyos lab. Candidates can also check out our newest achievements on Twitter: https://twitter.com/Escobar_Lab.
Candidates interested in applying should e-mail an application package, including a statement of interest, CV, and contact information for three references. Please send your application package to Dr. Natasha Pinto Medici (natasha.pintomedici@yale.edu) and Lyanne Delgado (lyanne.delgadocoka@yale.edu) . Please include your last name and reference to the job posting in the subject line.