Siyuan (Steven) Wang Lab in the Department of Genetics is seeking postgraduate research fellows interested in biotechnology development, cell biology, quantitative biology and biophysics of the mammalian genome.
Research in our lab focuses on the development and application of state-of-the-art imaging-based omics approaches to understand the spatial organization of mammalian genome and how it impacts cellular states. Recent advances include the development of a highly multiplexed and automated imaging method to trace the spatial folding of genome, or to profile the abundance and single-molecule localizations of hundreds-to-thousands of different RNA species in individual cells (Science 2016 and Science 2015). Please visit our lab website for more information: https://campuspress.yale.edu/wanglab/
The research fellow will actively engage in further development of this set of advanced techniques and/or the application of these techniques to different biological investigations. Individuals with prior experience of molecular and cellular biology, and of mammalian cell culture/tissue are strongly encouraged to apply.
The position is for 1 year, extendable to 2 or more years, with immediate start availability.
To apply, please send your CV and unofficial transcript, and have 2 letters of recommendation sent to firstname.lastname@example.org.
A postgraduate position available in the Division of Human Genetics at Yale Department of Psychiatry. The primary research focus will be to investigate the predisposition to psychiatric disorders and behavioral traits using genome-wide data. Individuals with a strong interest in genetic epidemiology, bioinformatics, statistics, or related fields are encouraged to apply. Computational or programming experience is highly desired.
The successful candidate will receive training in psychiatric genetics and actively participate in Dr. Renato Polimanti’s projects (http://bit.ly/2w7VZlT) funded by the Brain & Behavior Research Foundation, the American Foundation for Suicide Prevention, and the Simons Foundation Autism Research Initiative.
Please email your application including a cover letter, a detailed CV, and contact details of referees to email@example.com.
Nephrology Internal Medicine: Postgraduate associate training positions in clinical research available for 1-2 years.
This position is available for an immediate start date. The lab has several ongoing observational and interventional clinical research studies focusing on better understanding acute kidney injury and the ways it can be treated. The lab also has a focus on machine-learning and approaches to analyzing electronic health record data. This position is a wonderful opportunity for someone interested in learning clinical research methodologies.
Postgraduates will have the opportunity to interact with both patients and healthcare professionals in hospital, clinic and laboratory settings. Responsibilities may include, but are not limited to: assistance in clinical data collection, data quality management, recruiting and interacting with hospital patients for clinical studies, performing experiments, developing presentations, biospecimen processing, and reporting at team meetings. There is also an opportunity to participate in manuscript preparation and sub-studies.
Qualifications include completion of the pre-medical curriculum and/or BA/BS in the life sciences. Computational or programming experience is highly desired. Prior experience in a research lab or hospital is preferred but not required. We seek candidates with a strong desire to contribute to patient-oriented research.
The lab is composed of a great group of physicians, research fellows and study coordinators under Principal Investigator F. Perry Wilson. Interested applicants should send their resume with cover letter to firstname.lastname@example.org.
POSTGRADUATE POSITION IN NEURONAL RNA BIOLOGY
Postgraduate positions are available in Dr. Junjie Guo’s lab in the Department of Neuroscience at Yale School of Medicine. The Guo lab studies a number of inter-disciplinary questions at the intersection between RNA biology and neuroscience. Currently, we are interested in the roles of mRNA and noncoding RNA structures in neural development and a variety of neurodegenerative diseases, taking a combination of computational, biochemical, genetic, and genomic approaches.
You will receive training in a variety of molecular biology and cell biology techniques, actively participate in ongoing projects in the lab, and potentially lead an independent project through its completion.
Start date is flexible and can be as early as October 1, 2017. The position is for 1 year, extendable to 2 years. Recent graduates with strong interest in RNA biology and neuroscience are welcome to apply. Please email your application to email@example.com, including:
• A cover letter describing your past training, research interests and career goals
• A detailed CV
• Contact information of referees
For more information, please visit www.guo-lab.com or contact Dr. Guo by email.
Postgraduate position in the laboratory of Silvia Vilarinho, MD, PhD
The Vilarinho lab at Yale Liver Center and Department of Internal Medicine is seeking highly motivated and dedicated recent college graduates who are passionate about advancing the cellular and molecular understanding of liver function in health and disease.
Our laboratory is interested in using human genetics and genomics paired with highly informative cohorts of patients to discover new liver disease genes. Using cell based models and biochemistry we study how a mutant gene causes the liver phenotype. Thus, by uncovering new liver disease genes, we provide the patient with a diagnosis typically leading to new therapeutic options, prognosis and adequate genetic counseling at the same time we provide new insights into liver biology.
Your main responsabilities will include the developing of cell-based models to study novel gene mutations in liver function using CRISPR/Cas9 gene editing. Furthermore you will actively participate in the projects developing in the lab and will learn the wide array of techniques involved, including whole-exome sequencing analysis, confirmation of mutations using PCR and sanger sequencing, cloning, RNA isolation, rtPCR. Individuals with prior experience in liver, iPSC and/or bioinformatics/computational biology are strongly encouraged to apply.
The position is for 1 year, extendable to 2 years, with immediate start availability.
If you are interested in this position, please send (1) your CV, (2) a brief description of previous research experience and (3) an unofficial transcript to firstname.lastname@example.org.
A position is available for a full time research trainee (Post Graduate Associate) to work on projects involving molecular testing and measurement of immune biomarkers of solid tumors. The position would include patient interaction and laboratory work focusing on characterizing the immune cells in tumor samples using novel methods. The training would entail learning about molecular and immunologic abnormalities and working with oncologists and pathologists to identify unique features in human cancers that may impact treatment options. Candidates should have a Bachelors or Master’s degree. The position is full-time for a minimum of 1 year to start on or after June 1, 2017.
Post-graduate Research Opportunity in Yale’s Comprehensive Cancer Center
A post-graduate research associate position is available in Katerina Politi’s lab at Yale University. Research in the laboratory is focused on studying the tumor microenvironment of oncogene driven lung cancers and uncovering the mechanisms of resistance to drug therapies. This position is ideal for recent college undergraduates who plan to pursue a career in the biomedical sciences and would like exposure to the laboratory research environment beforehand. In this position post-graduates will learn common and useful methodologies that are practiced routinely in a molecular biology laboratory. Methods include, but are not limited to: PCR, cloning, DNA/RNA extraction, protein extraction, quantitative PCR, and cell culture. The candidate will also have the opportunity to work with and conduct research using genetically engineered mice and perform small animal imaging. In addition to practicing techniques learned during their undergraduate education, candidates will become familiar with how a research laboratory operates on a daily basis. Qualified candidates should have a Bachelor’s Degree in a scientific discipline, demonstrate a willingness and eagerness to learn many different scientific techniques, and must be motivated to learn and work independently with complex methodologies. A minimum and maximum two-year commitment is required. Candidates should send a Curriculum Vitae, a statement of research interests and career goals and the names of three references to: email@example.com.
Yale University is an Equal Opportunity Employer
Postgraduate position in Immunity, Autoimmune skin disease
A postgraduate associate is sought for a position in the laboratory of a Physician-Scientist at Yale School of Medicine. In this position, the candidate will learn to carry out basic science research to understand how immunity develops in health (vaccination, infection) and autoimmune skin disease. This work involves the use of mouse models, human blood and cellular and molecular immunology techniques.
The candidate will be trained to take on the following principle responsibilities: 1. Assist with mouse colony management and genotyping. 2. Perform immune cell isolation and subsequent characterization of phenotype and functional activities using a variety of techniques including flow cytometry, Elisa and Elispot assay, immunofluorescence histology and quantitative real-time PCR. 3. Assist with data analysis and interpretation. Attendance at weekly lab meetings and presentation of data generated is integral to the position.
The ideal candidate has majored in the Biological or Chemical Sciences but lacks a doctoral degree and is seeking advanced training for a defined period of time. Prior research experience is a plus, but is not required.
Interested candidates should email their CV including three references to Dr. Mary Tomayko, MD, PhD, Associate Professor of Dermatology at firstname.lastname@example.org.
We are looking for a thoughtful and motivated recent college graduate, with affinity for invertebrate biology, and an interest in learning cutting-edge molecular techniques. The candidate should hold a major in a biological discipline and have experience in a biological research environment. A strong sense of responsibility and a good eye for animal health are essential.
Our work focusses on the dynamics and regulation of pluripotent stem cells, using the freshwater flatworm Schmidtea mediterranea as a model. Schmidtea mediterranea has the ability to regenerate or repair any part of its body, and can even regrow its entire brain. We study the molecular processes involved in this amazing regenerative ability, using molecular imaging, confocal microscopy, single cell RNA sequencing, and computational analysis.
Your responsibilities will include the monitoring of a novel high-tech recirculation system for animal culture and the expansion of the animal colony. Furthermore you will actively participate in the projects developing in the lab and will learn the wide array of techniques involved, including cloning, RNA synthesis, imaging techniques, and cell sorting. We offer you a dynamic start-up environment in which you will have the chance to grow and really make a difference. For more information on the lab, see our website: www.vanwolfswinkellab.org.
The position is for 1 year, extendable to 2 years, and the ideal start date is August 2017.
To apply, send a CV and a cover letter explaining your motivation to email@example.com. Also please suggest a reference who can evaluate your lab experience.
Postgraduate Research Associate - Chung Lab
A post-undergraduate research associate position is available in the basic science laboratory studying ion channels and reproductive physiology (www.jeanjuchunglab.org). The appointee will assist the principal investigator and work with a post-doctoral associate in multiple aspects of the research project. These include: 1. Genotyping mice carrying mutations in genes that encode sperm-specific calcium channel and other fertility molecules; 2. Performing functional assays and molecular imaging to characterize successful mammalian fertilization and reproduction. The research associate will gain knowledge in gamete biology and skills in molecular & cellular biology, mouse genetics and genome editing, and advanced imaging.
Highly motivated and organized individuals with a Bachelor’s Degree (or Bachelor’s candidates) in Biological Sciences, Biochemistry, or Physics with demonstrated academic achievement are encourage to apply. Strong work ethic is a must and past experience in basic science research with mouse genetics or other molecular and cellular experience are preferred.
To apply, please send (1) a cover letter that describes what you did, and your motivation to apply, (2) a CV, and (3) 2-3 names of references to Jean-Ju Chung at firstname.lastname@example.org
The Yale Child Study Center is a leading institution for the study of human development, from pre-natal neural networks to children and adolescents affected by a wide range of psychiatric disorders and social disabilities. Our postgrad page is regularly updated with opportunities for postgrads to work on basic science in genetics, stem cells, and mice, neurodevelopmental research using multiple imaging methods to observe the brain, data analysis for healthcare quality measures, preschool training, and policy work.
Clink on link below to view current opportunities at the Yale Child Study Center : http://childstudycenter.yale.edu/training/postbacc1/index.aspx